Patent application number | Description | Published |
20080226739 | Hierarchically self-assembling linear-dendritic hybrid polymers for delivery of biologically active agents - A linear-dendritic hybrid polymer for encapsulating biologically active materials. The hybrid polymer includes a ligand for a predetermined target, a dendron, and a polyethylene glycol (PEG) chain linking the ligand to the dendron. | 09-18-2008 |
20090005727 | Acoustically controlled substance delivery device - Embodiments of a system including a remotely controlled substance delivery device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, a delivery device or related device may be placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. The concentration of a substance in the fluid to be delivered may be modified by a remote control signal. In selected embodiments, an acoustic control signal may be used. | 01-01-2009 |
20090018704 | Method and system for control of osmotic pump device - Embodiments of a system including a remotely controlled osmotic pump device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, an osmotic pump device is placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the osmotic pump device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used. | 01-15-2009 |
20090024114 | Method and system for control of osmotic pump device - Embodiments of a system including a remotely controlled osmotic pump device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, an osmotic pump device is placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the osmotic pump device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used. | 01-22-2009 |
20090054877 | Acoustically controlled substance delivery device - Embodiments of a system including a remotely controlled substance delivery device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, a delivery device or related device may be placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. The concentration of a substance in the fluid to be delivered may be modified by a remote control signal. In selected embodiments, an acoustic control signal may be used. | 02-26-2009 |
20090084844 | Specialty stents with flow control features or the like - Methods and systems are described for obtaining a parameter relating to a stent inventory shortage or to a specific patient and for configuring a stent in response. For example, the response may involve configuring a stent with a flow occlusion portion in response to the obtained parameter relating to the stent inventory shortage, configuring a stent with a flow occlusion portion in response to receiving the parameter relating to the specific patient, or specializing one or more stents in response to obtaining the parameter relating to the stent inventory shortage. | 04-02-2009 |
20090104250 | Medical or veterinary digestive tract utilization systems and methods - Systems and methods are described for implementing or deploying medical or veterinary utility modules (a) operable for mooring at least partly within a digestive tract, (b) small enough to pass through the tract per vias naturales and including a wireless-control component, (c) having one or more attachment protrusions positionable adjacent to a mucous membrane, (d) configured to facilitate redundant modes of attachment, (e) facilitating a “primary” material supply deployable within a stomach for an extended and/or controllable period, (f) moored by one or more adaptable extender modules supported by a subject's head or neck, and/or (g) configured to facilitate supporting at least a sensor within a subject's body lumen for up to a day or more. | 04-23-2009 |
20090105531 | Disintegrating digestive tract interaction system - Systems and methods are described for configuring several modules each individually small enough to pass through a digestive tract; and a tether or other means for releasably configuring at least the several modules in a group. Such a tether may (directly or indirectly) couple some of the modules via at least a gap in another module from which the tether may slip free, in some embodiments. Such methods may include modes of administering a medication or otherwise taking an action in response to the one or more phenomena. | 04-23-2009 |
20090105561 | Medical or veterinary digestive tract utilization systems and methods - Systems and methods are described for implementing or deploying medical or veterinary utility modules (a) operable for mooring at least partly within a digestive tract, (b) small enough to pass through the tract per vias naturales and including a wireless-control component, (c) having one or more attachment protrusions positionable adjacent to a mucous membrane, (d) configured to facilitate redundant modes of attachment, (e) facilitating a “primary” material supply deployable within a stomach for an extended and/or controllable period, (f) moored by one or more adaptable extender modules supported by a subject's head or neck, and/or (g) configured to facilitate supporting at least a sensor within a subject's body lumen for up to a day or more. | 04-23-2009 |
20090105694 | Medical or veterinary digestive tract utilization systems and methods - Systems and methods are described for implementing or deploying medical or veterinary utility modules (a) operable for mooring at least partly within a digestive tract, (b) small enough to pass through the tract per vias naturales and including a wireless-control component, (c) having one or more attachment protrusions positionable adjacent to a mucous membrane, (d) configured to facilitate redundant modes of attachment, (e) facilitating a “primary” material supply deployable within a stomach for an extended and/or controllable period, (f) moored by one or more adaptable extender modules supported by a subject's head or neck, and/or (g) configured to facilitate supporting at least a sensor within a subject's body lumen for up to a day or more. | 04-23-2009 |
20090110714 | Medical or veterinary digestive tract utilization systems and methods - Systems and methods are described for implementing or deploying medical or veterinary utility modules comprising a first module operable in a digestive or respiratory tract to engage a second module, optionally by a magnetic field. Alternatively or additionally, systems may be operable to remain in situ and also operable to permit a therapeutic material dispensation. In some contexts, for example, systems or methods may dispense a therapeutic material via a subject's throat or elsewhere in the digestive or respiratory tract. | 04-30-2009 |
20090111184 | Chromosome selection - Systems, methods, compositions and apparatus relating to genome, chromosome, and mitochondria selection are disclosed. | 04-30-2009 |
20090111185 | Female genome selection - Systems, methods, compositions and apparatus relating to genome, chromosome, and mitochondria selection are disclosed. | 04-30-2009 |
20090111764 | Mitochondrial selection - Systems, methods, compositions and apparatus relating to genome, chromosome, and mitochondria selection are disclosed. | 04-30-2009 |
20090112048 | Medical or veterinary digestive tract utilization systems and methods - Systems and methods are described for implementing or deploying medical or veterinary utility modules (a) operable for mooring at least partly within a digestive tract, (b) small enough to pass through the tract per vias naturales and including a wireless-control component, (c) having one or more attachment protrusions positionable adjacent to a mucous membrane, (d) configured to facilitate redundant modes of attachment, (e) facilitating a “primary” material supply deployable within a stomach for an extended and/or controllable period, (f) moored by one or more adaptable extender modules supported by a subject's head or neck, and/or (g) configured to facilitate supporting at least a sensor within a subject's body lumen for up to a day or more. | 04-30-2009 |
20090112189 | Medical or veterinary digestive tract utilization systems and methods - Systems and methods are described for implementing or deploying medical or veterinary utility modules (a) operable for mooring at least partly within a digestive tract, (b) small enough to pass through the tract per vias naturales and including a wireless-control component, (c) having one or more attachment protrusions positionable adjacent to a mucous membrane, (d) configured to facilitate redundant modes of attachment, (e) facilitating a “primary” material supply deployable within a stomach for an extended and/or controllable period, (f) moored by one or more adaptable extender modules supported by a subject's head or neck, and/or (g) configured to facilitate supporting at least a sensor within a subject's body lumen for up to a day or more. | 04-30-2009 |
20090112190 | Medical or veterinary digestive tract utilization systems and methods - Systems and methods are described for implementing or deploying medical or veterinary utility modules comprising a first module operable in a digestive or respiratory tract to engage a second module, optionally by a magnetic field. Alternatively or additionally, systems may be operable to remain in situ and also operable to permit a therapeutic material dispensation. In some contexts, for example, systems or methods may dispense a therapeutic material via a subject's throat or elsewhere in the digestive or respiratory tract. | 04-30-2009 |
20090112191 | Medical or veterinary digestive tract utilization systems and methods - Systems and methods are described for implementing or deploying medical or veterinary utility modules comprising a first module operable in a digestive or respiratory tract to engage a second module, optionally by a magnetic field. Alternatively or additionally, systems may be operable to remain in situ and also operable to permit a therapeutic material dispensation. In some contexts, for example, systems or methods may dispense a therapeutic material via a subject's throat or elsewhere in the digestive or respiratory tract. | 04-30-2009 |
20090137866 | Medical or veterinary digestive tract utilization systems and methods - Systems and methods are described for implementing or deploying medical or veterinary utility modules (a) operable for mooring at least partly within a digestive tract, (b) small enough to pass through the tract per vias naturales and including a wireless-control component, (c) having one or more attachment protrusions positionable adjacent to a mucous membrane, (d) configured to facilitate redundant modes of attachment, (e) facilitating a “primary” material supply deployable within a stomach for an extended and/or controllable period, (f) moored by one or more adaptable extender modules supported by a subject's head or neck, and/or (g) configured to facilitate supporting at least a sensor within a subject's body lumen for up to a day or more. | 05-28-2009 |
20090162249 | Acoustically controlled reaction device - Embodiments of a system including a remotely controlled reaction device and associated controller are described. Methods of use and control of the device are also disclosed. According to various embodiments, a reaction device is placed in an environment in order to perform a chemical reaction in an environment. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. In selected embodiments, an acoustic control signal may be used. | 06-25-2009 |
20090162250 | Acoustically controlled reaction device - Embodiments of a system including a remotely controlled reaction device and associated controller are described. Methods of use and control of the device are also disclosed. According to various embodiments, a reaction device is placed in an environment in order to perform a chemical reaction in an environment. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. In selected embodiments, an acoustic control signal may be used. | 06-25-2009 |
20090192449 | Adaptive dispensation in a digestive tract - Systems and methods are described for implementing a bioactive material selection from within a digestive tract and transmitting a wireless signal indicating at least the bioactive material selection from within the digestive tract. | 07-30-2009 |
20090263359 | Particulate Delivery Vehicles for Embryoid Bodies - The present invention provides a vehicle for delivering various chemicals, compositions and proteins to stem cells and embryoid bodies. The vehicle may be biocompatible and biodegradable polymer microparticles. Typically the particles will contain at least a growth factor for delivery to the embryoid bodies, and generally the growth factor induces differentiation of the cells in the embryoid body along a specific lineage. The present invention also provides methods for directing differentiation of the cells in the embryoid body. | 10-22-2009 |
20100009914 | METHOD OF PROTECTING SENSITIVE MOLECULES FROM A PHOTO-POLYMERIZING ENVIRONMENT - In one embodiment, the present invention is a substrate system of photo-polymerizable monomers and bioactive molecules admixed with the monomers and shielded from the monomers by an insoluble material that undergoes a solid-gel transition at body temperature. Upon polymerization, the monomers produce a cross-linked structure and the shielded bioactive molecules are protected from attack in the polymerized environment. In different aspects, the substrate system is used for drug delivery and tissue engineering and protection of enzymes, proteins and growth factors. In another embodiment, the present invention is a drug delivery system of photo-polymerizable monomers, drug molecules associated with the monomers and shielded from the monomers by an insoluble material that undergoes a solid-gel transition at body temperature, and a photopolymerizing means for polymerizing the monomers to produce a cross-linked structure including the drug molecules. | 01-14-2010 |
20100030185 | Remote controller for substance delivery system - Embodiments of a system including a remotely controlled substance delivery device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, a delivery device or related device may be placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. The concentration of a substance in the fluid to be delivered may be modified by a remote control signal. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used. | 02-04-2010 |
20100076414 | Remote control of substance delivery system - Embodiments of a system including a remotely controlled substance delivery device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, a delivery device or related device may be placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. The concentration of a substance in the fluid to be delivered may be modified by a remote control signal. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used. | 03-25-2010 |
20100076415 | Remote control of substance delivery system - Embodiments of a system including a remotely controlled substance delivery device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, a delivery device or related device may be placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. The concentration of a substance in the fluid to be delivered may be modified by a remote control signal. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used. | 03-25-2010 |
20100092425 | Nicotine Immunonanotherapeutics - The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface having a plurality of nicotine moieties. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof. For example, the present invention nanocarriers capable of eliciting an immune response and the production of anti-nicotine antibodies. | 04-15-2010 |
20100099176 | Systems for genome selection - Systems, methods, compositions and apparatus relating to genome selection are disclosed. | 04-22-2010 |
20100099197 | Systems for genome selection - Systems, methods, compositions and apparatus relating to genome selection are disclosed. | 04-22-2010 |
20100129392 | Targeting of Antigen Presenting Cells with Immunonanotherapeutics - The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface. The nanocarriers are capable of targeting antigen presenting cells when administered to a subject. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof. | 05-27-2010 |
20100129439 | Adjuvant Incorporation in Immunonanotherapeutics - The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface and an immunostimulatory moiety. In some embodiments, the immunostimulatory moiety is an adjuvant. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof. | 05-27-2010 |
20100163020 | Method for administering an inhalable compound - A method may include dispensing a dose of an inhalable compound according to a dosing instruction set; and maintaining a hands-free article for dispensing the inhalable compound in an operable dispensing position. | 07-01-2010 |
20100163024 | Methods and systems for presenting an inhalation experience - Methods, computer program products, and systems are described that include accepting an indication of a bioactive agent-dispensing inhalation device and presenting an indication of an artificial sensory experience at least partially based on accepting an indication of a bioactive agent-dispensing inhalation device. | 07-01-2010 |
20100163025 | Methods and systems for presenting an inhalation experience - Methods, computer program products, and systems are described that include accepting an indication of a bioactive agent-dispensing inhalation device and presenting an indication of an artificial sensory experience at least partially based on accepting an indication of a bioactive agent-dispensing inhalation device. | 07-01-2010 |
20100163026 | Methods and systems for presenting an inhalation experience - Methods, computer program products, and systems are described that include accepting an indication of at least one health-related condition and presenting an indication of at least one artificial sensory experience and an indication of at least one inhalation therapy at least partially based on the accepting at least one indication of a health-related condition. | 07-01-2010 |
20100163027 | Methods and systems for presenting an inhalation experience - Methods, computer program products, and systems are described that include accepting at least one indication of use of an inhalation device configured to dispense a bioactive agent to an individual and presenting at least one artificial sensory experience to monitor at least one desired effect of the bioactive agent on the individual. | 07-01-2010 |
20100163028 | Methods and systems for presenting an inhalation experience - Methods, computer program products, and systems are described that include monitoring at least one health attribute of an individual during an artificial sensory experience, associating a characteristic of the artificial sensory experience with the at least one health attribute of the individual, and modifying at least one of an inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on associating a characteristic of the artificial sensory experience with the at least one health attribute of the individual. | 07-01-2010 |
20100163029 | Method for administering an inhalable compound - A method may include dispensing a dose of an inhalable compound according to a dosing instruction set; and maintaining a hands-free article for dispensing the inhalable compound in an operable dispensing position. | 07-01-2010 |
20100163033 | Methods and systems for presenting an inhalation experience - Methods, computer program products, and systems are described that include accepting an indication of at least one health-related condition and presenting an indication of at least one artificial sensory experience and an indication of at least one inhalation therapy at least partially based on the accepting at least one indication of a health-related condition. | 07-01-2010 |
20100163034 | Methods and systems for presenting an inhalation experience - Methods, computer program products, and systems are described that include detecting in an exhalant at least one indication of bioactive agent use by an individual and altering at least one artificial sensory experience at least partly based on the at least one indication of bioactive agent use by an individual. | 07-01-2010 |
20100163035 | Methods and systems for presenting an inhalation experience - Methods, computer program products, and systems are described that include accepting at least one indication of use of an inhalation device configured to dispense a bioactive agent to an individual and presenting at Least one artificial sensory experience to monitor at Least one side effect of the bioactive agent on the individual. | 07-01-2010 |
20100163036 | Methods and systems for presenting an inhalation experience - Methods, computer program products, and systems are described that include measuring at least one effect of an inhalation device-dispensed bioactive agent and artificial sensory experience on an individual and modifying at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on the at least one effect. | 07-01-2010 |
20100163037 | Methods and systems for presenting an inhalation experience - Methods, computer program products, and systems are described that include measuring at least one effect of an inhalation device-dispensed bioactive agent and artificial sensory experience on an individual and modifying at least one of the inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on the at least one effect. | 07-01-2010 |
20100163038 | Methods and systems for presenting an inhalation experience - Methods, computer program products, and systems are described that include accepting an indication of a schedule for administration of an inhalation device-dispensed bioactive agent to an individual and presenting an indication of an artificial sensory experience at least partly based on the accepting an indication of the schedule for administration of the inhalation device-dispensed bioactive agent to the individual. | 07-01-2010 |
20100163039 | Method for administering an inhalable compound - A method may include dispensing a dose of an inhalable compound according to a dosing instruction set; and maintaining a hands-free article for dispensing the inhalable compound in an operable dispensing position. | 07-01-2010 |
20100163040 | Method for administering an inhalable compound - A method may include dispensing a dose of an inhalable compound according to a dosing instruction set; and maintaining a hands-free article for dispensing the inhalable compound in an operable dispensing position. | 07-01-2010 |
20100163041 | Method for administering an inhalable compound - A method may include dispensing a dose of an inhalable compound according to a dosing instruction set; and maintaining a hands-free article for dispensing the inhalable compound in an operable dispensing position. | 07-01-2010 |
20100164729 | Methods and systems for presenting an inhalation experience - Methods, computer program products, and systems are described that include accepting an indication of an individual's compliance with an artificial sensory experience and presenting an indication of an inhalation device-dispensed bioactive agent at least partially based on the indication of the individual's compliance with the artificial sensory experience. | 07-01-2010 |
20100166613 | Methods and systems for presenting an inhalation experience - Methods, computer program products, and systems are described that include detecting in an exhalant at least one indication of bioactive agent use by an individual and altering at least one artificial sensory experience at least partly based on the at least one indication of bioactive agent use by an individual. | 07-01-2010 |
20100168525 | Methods and systems for presenting an inhalation experience - Methods, computer program products, and systems are described that include accepting at least one indication of use of an inhalation device configured to dispense a bioactive agent to an individual and presenting at least one artificial sensory experience to monitor at least one desired effect of the bioactive agent on the individual. | 07-01-2010 |
20100168529 | Methods and systems for presenting an inhalation experience - Methods, computer program products, and systems are described that include monitoring at least one health attribute of an individual during an artificial sensory experience, associating a characteristic of the artificial sensory experience with the at least one health attribute of the individual, and modifying at least one of an inhalation device-dispensed bioactive agent or the artificial sensory experience at least partially based on associating a characteristic of the artificial sensory experience with the at least one health attribute of the individual. | 07-01-2010 |
20100168602 | Methods and systems for presenting an inhalation experience - Methods, computer program products, and systems are described that include accepting at least one indication of use of an inhalation device configured to dispense a bioactive agent to an individual and presenting at least one artificial sensory experience to monitor at least one side effect of the bioactive agent on the individual. | 07-01-2010 |
20100169259 | Methods and systems for presenting an inhalation experience - Methods, computer program products, and systems are described that include accepting an indication of an individual's compliance with an artificial sensory experience and presenting an indication of an inhalation device-dispensed bioactive agent at least partially based on the indication of the individual's compliance with the artificial sensory experience. | 07-01-2010 |
20100169260 | Methods and systems for presenting an inhalation experience - Methods, computer program products, and systems are described that include accepting an indication of a schedule for administration of an inhalation device-dispensed bioactive agent to an individual and presenting an indication of an artificial sensory experience at least partly based on the accepting an indication of the schedule for administration of the inhalation device-dispensed bioactive agent to the individual. | 07-01-2010 |
20100173308 | Systems for genome selection - Systems, methods, compositions and apparatus relating to genome selection are disclosed. | 07-08-2010 |
20100174493 | Systems for genome selection - Systems, methods, compositions and apparatus relating to genome selection are disclosed. | 07-08-2010 |
20100178687 | Systems for genome selection - Systems, methods, compositions and apparatus relating to genome selection are disclosed. | 07-15-2010 |
20100183727 | Immunonanotherapeutics that Provide IgG Humoral Response Without T-Cell Antigen - The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides synthetic nanocarriers capable of eliciting an immune system response in the form of antibody production, wherein the nanocarriers lack any T cell antigens. In some embodiments, the invention provides nanocarriers that comprise an immunofeature surface, which provides high avidity binding of the nanocarriers to antigen presenting cells. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof. | 07-22-2010 |
20100196899 | Systems for genome selection - Systems, methods, compositions and apparatus relating to genome selection are disclosed. | 08-05-2010 |
20100197002 | Systems for genome selection - Systems, methods, compositions and apparatus relating to genome selection are disclosed. | 08-05-2010 |
20100203530 | Systems for genome selection - Systems, methods, compositions and apparatus relating to genome selection are disclosed. | 08-12-2010 |
20100216226 | Device, system, and method for controllably reducing inflammatory mediators in a subject - Devices, systems, and methods are provided for controlling an inflammatory response in a subject. Devices, systems, and methods are provided that alter the functional structure of one or more inflammatory mediators in the peripheral blood of the subject. The device or system is useful in a method for treating an inflammatory disease or condition in the subject. | 08-26-2010 |
20100217172 | Device, system, and method for controllably reducing inflammatory mediators in a subject - Devices, systems, and methods are provided for controlling an inflammatory response in a subject. Devices, systems, and methods are provided that alter the functional structure of one or more inflammatory mediators in the peripheral blood of the subject. The device or system is useful in a method for treating an inflammatory disease or condition in the subject. | 08-26-2010 |
20100217173 | Device, system, and method for controllably reducing inflammatory mediators in a subject - Devices, systems, and methods are provided for controlling an inflammatory response in a subject. Extracorporeal devices, systems, and methods are provided that alter the functional structure of one or more inflammatory mediators in the peripheral blood of the subject. The device or system is useful in a method for treating an inflammatory disease or condition in the subject. | 08-26-2010 |
20100221721 | System for genome selection - Systems, methods, compositions and apparatus relating to genome selection are disclosed. | 09-02-2010 |
20100228234 | Device for actively removing a target cell from blood or lymph of a vertebrate subject - Devices, systems, and methods are described herein for controlling the level of one or more target cell types in the blood fluid and/or lymph fluid of a vertebrate subject. Devices and systems are provided that include a body defining at least one lumen configured for fluid flow; at least one controllable flow barrier to the at least one lumen; one or more sensor configured to detect one or more target cell types in blood fluid or lymph fluid of a vertebrate subject; at least one treatment region disposed within the at least one lumen; at least one reactive component disposed in the at least one treatment region, the at least one reactive component configured to modulate a physiological effect of the one or more target cell types in the vertebrate subject; and at least one controller in communication with the one or more sensor and in communication with the at least one controllable flow barrier to the at least one lumen; wherein the at least one controller is configured to open or close the at least one controllable flow barrier in response to the one or more sensor. | 09-09-2010 |
20100255057 | Device for actively removing a target cell from blood or lymph of a vertebrate subject - Devices, systems, and methods are described herein for controlling the level of one or more target cell types in the blood fluid and/or lymph fluid of a vertebrate subject. Devices and systems are provided that include a body defining at least one lumen configured for fluid flow; at least one controllable flow barrier to the at least one lumen; one or more sensor configured to detect one or more target cell types in blood fluid or lymph fluid of a vertebrate subject; at least one treatment region disposed within the at least one lumen; at least one reactive component disposed in the at least one treatment region, the at least one reactive component configured to modulate a physiological effect of the one or more target cell types in the vertebrate subject; and at least one controller in communication with the one or more sensor and in communication with the at least one controllable flow barrier to the at least one lumen; wherein the at least one controller is configured to open or close the at least one controllable flow barrier in response to the one or more sensor. | 10-07-2010 |
20100255489 | Systems for genome selection - Systems, methods, compositions and apparatus relating to genome selection are disclosed. | 10-07-2010 |
20100268199 | Device for passively removing a target component from blood or lymph of a vertebrate subject - Devices, systems, and methods are described herein for controlling or modulating the levels of one or more target components in the blood and/or lymph of a vertebrate subject. Devices and systems are provided that include a body defining at least one lumen configured for fluid flow; at least one controllable flow barrier to fluid flow into the at least one lumen; at least one first reservoir disposed within the body and configured to include one or more bifunctional tags, wherein the one or more bifunctional tags are configured to selectively bind to one or more target components in one or more of blood fluid or lymph fluid of a vertebrate subject; at least one treatment region disposed within the at least one lumen; and at least one second reservoir disposed in the at least one treatment region and configured to include one or more reactive components, wherein the one or more reactive components are configured to sequester the one or more bifunctional tags when bound to the one or more target components. | 10-21-2010 |
20100272771 | Device including bone cage and method for treatment of disease in a subject - Devices, methods, and systems are described for controlling pathogenic condition or disease in a subject. Devices are described that include one or more bone cages. The device including one or more bone cages can be configured to include one or more immunogens and one or more adjuvants. The device including one or more bone cages can be configured to, and/or structured to at least partially or completely surround one or more cells or tissues that produce one or more immunogens and/or one or more adjuvants. The device is useful in a method for treating a pathogenic condition or disease in the subject. | 10-28-2010 |
20100272776 | Device including bone cage and method for treatment of disease in a subject - Devices, methods, and systems are described for controlling pathogenic condition or disease in a subject. Devices are described that include one or more bone cages. The device including one or more bone cages can be configured to include one or more immunogens and one or more adjuvants. The device including one or more bone cages can be configured to, and/or structured to at least partially or completely surround one or more cells or tissues that produce one or more immunogens and/or one or more adjuvants. The device is useful in a method for treating a pathogenic condition or disease in the subject. | 10-28-2010 |
20100280686 | Awarding privileges to a vehicle based upon one or more fuel utilization characteristics - A device may include a determination module for determining at least one of a status indicative of combustible fuel utilization or a status indicative of electricity utilization for propelling a hybrid vehicle; and a transmitter coupled with the determination module for transmitting the at least one of the status indicative of combustible fuel utilization or the status indicative of electricity utilization for the hybrid vehicle to an off-site entity. | 11-04-2010 |
20100280688 | Awarding standings to a vehicle based upon one or more fuel utilization characteristics - A method may include receiving at least one of a status indicative of combustible fuel utilization or a status indicative of electricity utilization for a hybrid vehicle; and allocating a standing based upon the at least one of the status indicative of combustible fuel utilization or the status indicative of electricity utilization for the vehicle, wherein the standing is allocated upon receipt of the status. | 11-04-2010 |
20100280689 | Awarding standings to a vehicle based upon one or more fuel utilization characteristics - A method may include receiving at least one of a status indicative of combustible fuel utilization or a status indicative of electricity utilization for a hybrid vehicle; and allocating a standing based upon the at least one of the status indicative of combustible fuel utilization or the status indicative of electricity utilization for the vehicle, wherein the standing is allocated upon receipt of the status. | 11-04-2010 |
20100280690 | Awarding standings to a vehicle based upon one or more fuel utilization characteristics - A method may include receiving at least one of a status indicative of combustible fuel utilization or a status indicative of electricity utilization for a hybrid vehicle; and allocating a standing based upon the at least one of the status indicative of combustible fuel utilization or the status indicative of electricity utilization for the vehicle, wherein the standing is allocated upon receipt of the status. | 11-04-2010 |
20100280691 | Awarding standings to a vehicle based upon one or more fuel utilization characteristics - A method may include receiving at least one of a status indicative of combustible fuel utilization or a status indicative of electricity utilization for a hybrid vehicle; and allocating a standing based upon the at least one of the status indicative of combustible fuel utilization or the status indicative of electricity utilization for the vehicle, wherein the standing is allocated upon receipt of the status. | 11-04-2010 |
20100280692 | Awarding standings to a vehicle based upon one or more fuel utilization characteristics - A method may include receiving at least one of a status indicative of combustible fuel utilization or a status indicative of electricity utilization for a hybrid vehicle; and allocating a standing based upon the at least one of the status indicative of combustible fuel utilization or the status indicative of electricity utilization for the vehicle, wherein the standing is allocated upon receipt of the status. | 11-04-2010 |
20100280693 | Awarding standings to a vehicle based upon one or more fuel utilization characteristics - A method may include receiving at least one of a status indicative of combustible fuel utilization or a status indicative of electricity utilization for a hybrid vehicle; and allocating a standing based upon the at least one of the status indicative of combustible fuel utilization or the status indicative of electricity utilization for the vehicle, wherein the standing is allocated upon receipt of the status. | 11-04-2010 |
20100280703 | Awarding Privileges to a vehicle based upon one or more fuel utilization characteristics - A device may include a determination module for determining at least one of a status indicative of combustible fuel utilization or a status indicative of electricity utilization for propelling a hybrid vehicle; and a transmitter coupled with the determination module for transmitting the at least one of the status indicative of combustible fuel utilization or the status indicative of electricity utilization for the hybrid vehicle to an off-site entity. | 11-04-2010 |
20100280704 | Awarding standings to a vehicle based upon one or more fuel utilization characteristics - A method may include, but is not limited to, receiving a status indicative of combustible fuel utilization in comparison to electricity utilization for a vehicle and conveying a standing, the standing based upon the status indicative of combustible fuel utilization in comparison to electricity utilization for the vehicle. | 11-04-2010 |
20100280705 | Awarding standings to a vehicle based upon one or more fuel utilization characteristics - A method may include, but is not limited to, transmitting to an off-site entity a status indicative of combustible fuel utilization in comparison to electricity utilization from a vehicle. | 11-04-2010 |
20100280706 | Awarding standings to a vehicle based upon one or more fuel utilization characteristics - A method may include, but is not limited to, querying a hybrid vehicle for at least one of a status indicative of combustible fuel utilization or a status indicative of electricity utilization for the vehicle. | 11-04-2010 |
20100280707 | Awarding standings to a vehicle based upon one or more fuel utilization characteristics - A method may include, but is not limited to, receiving at least one of a status indicative of combustible fuel utilization or a status indicative of electricity utilization for a hybrid vehicle and forwarding to an off-site entity the at least one of the status indicative of combustible fuel utilization or the status indicative of electricity utilization for the vehicle. | 11-04-2010 |
20100280708 | Awarding standings to a vehicle based upon one or more fuel utilization characteristics - A method may include, but is not limited to, transmitting to an off-site entity at least one of a status indicative of combustible fuel utilization or a status indicative of electricity utilization from a hybrid vehicle. | 11-04-2010 |
20100280709 | Awarding standings to a vehicle based upon one or more fuel utilization characteristics - A method may include, but is not limited to, receiving a status indicative of combustible fuel utilization in comparison to electricity utilization for a vehicle and forwarding to an off-site entity the status indicative of combustible fuel utilization in comparison to electricity utilization for the vehicle. | 11-04-2010 |
20100280885 | Awarding privileges to a vehicle based upon one or more fuel utilization characteristics - A device may include a determination module for determining at least one of a status indicative of combustible fuel utilization or a status indicative of electricity utilization for propelling a hybrid vehicle; and a transmitter coupled with the determination module for transmitting the at least one of the status indicative of combustible fuel utilization or the status indicative of electricity utilization for the hybrid vehicle to an off-site entity. | 11-04-2010 |
20100280886 | Awarding privileges to a vehicle based upon one or more fuel utilization characteristics - A device may include a determination module for determining at least one of a status indicative of combustible fuel utilization or a status indicative of electricity utilization for propelling a hybrid vehicle; and a transmitter coupled with the determination module for transmitting the at Least one of the status indicative of combustible fuel utilization or the status indicative of electricity utilization for the hybrid vehicle to an off-site entity. | 11-04-2010 |
20100280887 | Awarding privileges to a vehicle based upon one or more fuel utilization characteristics - A device may include a determination module for determining at least one of a status indicative of combustible fuel utilization or a status indicative of electricity utilization for propelling a hybrid vehicle; and a transmitter coupled with the determination module for transmitting the at least one of the status indicative of combustible fuel utilization or the status indicative of electricity utilization for the hybrid vehicle to an off-site entity. | 11-04-2010 |
20100280888 | Awarding privileges to a vehicle based upon one or more fuel utilization characteristics - A device may include a determination module for determining at least one of a status indicative of combustible fuel utilization or a status indicative of electricity utilization for propelling a hybrid vehicle; and a transmitter coupled with the determination module for transmitting the at least one of the status indicative of combustible fuel utilization or the status indicative of electricity utilization for the hybrid vehicle to an off-site entity. | 11-04-2010 |
20100298766 | Device for passively removing a target component from blood or lymph of a vertebrate subject - Devices, systems, and methods are described herein for controlling or modulating the levels of one or more target components in the blood and/or lymph of a vertebrate subject. Devices and systems are provided that include a body defining at least one lumen configured for fluid flow; at least one controllable flow barrier to fluid flow into the at least one lumen; at least one first reservoir disposed within the body and configured to include one or more bifunctional tags, wherein the one or more bifunctional tags are configured to selectively bind to one or more target components in one or more of blood fluid or lymph fluid of a vertebrate subject; at least one treatment region disposed within the at least one lumen; and at least one second reservoir disposed in the at least one treatment region and configured to include one or more reactive components, wherein the one or more reactive components are configured to sequester the one or more bifunctional tags when bound to the one or more target components. | 11-25-2010 |
20110021965 | ADHESIVE ARTICLES - An adhesive article includes a biocompatible and at least partially biodegradable substrate having a surface; and a plurality of protrusions extending from the surface. The protrusions include a biocompatible and at least partially biodegradable material, and have an average height of less than approximately 1,000 micrometers. | 01-27-2011 |
20110034908 | Device for actively removing a target component from blood or lymph of a vertebrate subject - Devices, systems, and methods are disclosed herein for modulating the levels of one or more target components in the blood and/or lymph of a vertebrate subject for treatment of a disease or condition in the vertebrate subject. An implantable device is provided which includes a body defining at least one lumen configured for fluid flow; at least one first reservoir in communication with at least one lumen; one or more energy sources configured to provide energy to elicit one or more signal responses associated with one or more labels that bind to one or more target components in one or more of blood fluid or lymph fluid of the vertebrate subject; one or more sensors configured to detect the one or more signal responses associated with one or more labeled target components; and one or more reactive components in communication with the at least one lumen for release responsive to the one or more sensors. | 02-10-2011 |
20110082412 | Device for actively removing a target component from blood or lymph of a vertebrate subject - Devices, systems, and methods are disclosed herein for modulating the levels of one or more target components in the blood and/or lymph of a vertebrate subject for treatment of a disease or condition in the vertebrate subject. An implantable device is provided which includes a body defining at least one lumen configured for fluid flow; at least one first reservoir in communication with at least one lumen; one or more energy sources configured to provide energy to elicit one or more signal responses associated with one or more labels that bind to one or more target components in one or more of blood fluid or lymph fluid of the vertebrate subject; one or more sensors configured to detect the one or more signal responses associated with one or more labeled target components; and one or more reactive components in communication with the at least one lumen for release responsive to the one or more sensors. | 04-07-2011 |
20110106354 | Awarding standings to a vehicle based upon one or more fuel utilization characteristics - A method may include, but is not limited to, querying a vehicle for a status indicative of combustible fuel utilization in comparison to electricity utilization for the vehicle. | 05-05-2011 |
20110106591 | Awarding standings to a vehicle based upon one or more fuel utilization characteristics - A method may include, but is not limited to, receiving at least one of a status indicative of combustible fuel utilization or a status indicative of electricity utilization for a hybrid vehicle and conveying a standing, the standing based upon the at least one of the status indicative of combustible fuel utilization or the status indicative of electricity utilization for the vehicle. | 05-05-2011 |
20110143355 | Systems for genome selection - Systems, methods, compositions and apparatus relating to genome selection are disclosed. | 06-16-2011 |
20110148753 | Identifying a characteristic of an individual utilizing facial recognition and providing a display for the individual - A method may include automatically remotely identifying at least one characteristic of an individual via facial recognition; and providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. A system may include a facial recognition module configured for automatically remotely identifying at least one characteristic of an individual via facial recognition; and a display module coupled with the facial recognition module, the display module configured for providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. | 06-23-2011 |
20110150276 | Identifying a characteristic of an individual utilizing facial recognition and providing a display for the individual - A method may include automatically remotely identifying at least one characteristic of an individual via facial recognition; and providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. A system may include a facial recognition module configured for automatically remotely identifying at least one characteristic of an individual via facial recognition; and a display module coupled with the facial recognition module, the display module configured for providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. | 06-23-2011 |
20110150294 | Identifying a characteristic of an individual utilizing facial recognition and providing a display for the individual - A method may include automatically remotely identifying at least one characteristic of an individual via facial recognition; and providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. A system may include a facial recognition module configured for automatically remotely identifying at least one characteristic of an individual via facial recognition; and a display module coupled with the facial recognition module, the display module configured for providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. | 06-23-2011 |
20110150295 | Identifying a characteristic of an individual utilizing facial recognition and providing a display for the individual - A method may include automatically remotely identifying at least one characteristic of an individual via facial recognition; and providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. A system may include a facial recognition module configured for automatically remotely identifying at least one characteristic of an individual via facial recognition; and a display module coupled with the facial recognition module, the display module configured for providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. | 06-23-2011 |
20110150296 | Identifying a characteristic of an individual utilizing facial recognition and providing a display for the individual - A method may include automatically remotely identifying at least one characteristic of an individual via facial recognition; and providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. A system may include a facial recognition module configured for automatically remotely identifying at least one characteristic of an individual via facial recognition; and a display module coupled with the facial recognition module, the display module configured for providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. | 06-23-2011 |
20110150297 | Identifying a characteristic of an individual utilizing facial recognition and providing a display for the individual - A method may include automatically remotely identifying at least one characteristic of an individual via facial recognition; and providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. A system may include a facial recognition module configured for automatically remotely identifying at least one characteristic of an individual via facial recognition; and a display module coupled with the facial recognition module, the display module configured for providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. | 06-23-2011 |
20110150298 | Identifying a characteristic of an individual utilizing facial recognition and providing a display for the individual - A method may include automatically remotely identifying at least one characteristic of an individual via facial recognition; and providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. A system may include a facial recognition module configured for automatically remotely identifying at least one characteristic of an individual via facial recognition; and a display module coupled with the facial recognition module, the display module configured for providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. | 06-23-2011 |
20110150299 | Identifying a characteristic of an individual utilizing facial recognition and providing a display for the individual - A method may include automatically remotely identifying at least one characteristic of an individual via facial recognition; and providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. A system may include a facial recognition module configured for automatically remotely identifying at least one characteristic of an individual via facial recognition; and a display module coupled with the facial recognition module, the display module configured for providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. | 06-23-2011 |
20110183867 | Polymer arrays for biofilm adhesion testing - This invention relates to a method of screening arrays of polymers having pre-determined surface energies. The polymer arrays of the present invention can be used to screen for microorganism adherence. More specifically the arrays can be used to screen for adherence of particular bacteria or fungi to particular polymers in the array. Furthermore, this invention relates to a method combining in-situ polymer synthesis with physico-chemical characterisation of the resulting polymer array and subsequent biological assays of bacterial or fungal adherence. This allows for high throughput screening and characterisation of candidate polymers which are not susceptible to bacterial or fungal adherence or which can be used to support bacterial or fungal adherence where such is required. The arrays can also be used to screen for inhibition or promotion of biofilm formation. | 07-28-2011 |
20110206245 | Identifying a characteristic of an individual utilizing facial recognition and providing a display for the individual - A method may include automatically remotely identifying at least one characteristic of an individual via facial recognition; and providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. A system may include means for automatically remotely identifying at least one characteristic of an individual via facial recognition; and means for providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. | 08-25-2011 |
20110211738 | Identifying a characteristic of an individual utilizing facial recognition and providing a display for the individual - A method may include automatically remotely identifying at least one characteristic of an individual via facial recognition; and providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. A system may include means for automatically remotely identifying at least one characteristic of an individual via facial recognition; and means for providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. | 09-01-2011 |
20110211739 | Identifying a characteristic of an individual utilizing facial recognition and providing a display for the individual - A method may include automatically remotely identifying at least one characteristic of an individual via facial recognition; and providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. A system may include means for automatically remotely identifying at least one characteristic of an individual via facial recognition; and means for providing a display for the individual, the display having a content at least partially based on the identified at least one characteristic of the individual. | 09-01-2011 |
20110256205 | Bone cell delivery device - Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects. | 10-20-2011 |
20110278942 | Wearable power source carryable by a health care provider - Described embodiments include a system, an apparatus, and a method. A described system includes a portable energy source configured to supply electrical or radiant power, and configured to be carried proximate to a first body portion of a health care provider. The system also includes a portable power transmitter configured to wirelessly transfer the electrical or radiant power supplied by the portable energy source from the portable energy source to a wireless power receiver connected to a handheld medical device. The system further includes a connective structure configured to transfer the electrical or radiant power supplied by the portable energy source between the portable energy source and the portable power transmitter, and configured to be carried proximate to the body of the health care provider. | 11-17-2011 |
20110278943 | System including wearable power receiver and wearable power-output device - Described embodiments include a system, apparatus, and method. A described wearable power supply system configured to be usable after sterilization includes a portable energy source configured to supply electrical or radiant power, and configured to be carried by a person proximate to a first body portion of the person. The system also includes a portable power-output device configured to interact with a power-receiving device connected to a powerable handheld device, and configured to be carried by the person proximate to a second body portion at a position distal of a shoulder joint of the person. If interacting, the supplied electrical or radiant power is transferred from the portable power-output device to the power-receiving device. The system further includes a connective structure configured to transfer the supplied electrical or radiant power between the portable energy source and the power-output device. | 11-17-2011 |
20110278944 | Wearable power-output device operable to deliver wirelessly received power - Described embodiments include a system, an apparatus, and a method. A described system includes a power receiver configured to wirelessly receive a first power from a wireless power transmitter source, and configured to be carried by a health care provider. The system also includes an energy storage device configured to store energy derived from the first power, to supply a second power, and configured to be carried by the health care provider. The system further includes a power-output device configured to interact with a power-receiving device connected to a handheld medical device, and configured to be carried by the health care provider proximate. If interacting, a third power is transferred from the power-output device to the power-receiving device. The system also includes a first connective structure configured to transfer the first power between the portable power receiver and the energy storage device, and configured to be carried by the health care provider. | 11-17-2011 |
20110278956 | System including wearable power receiver and wearable power-output device - Described embodiments include a system, apparatus, and method. A described system includes a power-receiving connector configured to be usable after sterilization, to releasably couple with a power-source connector, and configured to be carried by a health care provider proximate to a first body portion. If coupled, the power-receiving connector is operable to receive an electrical or radiant power from the power-source connector. The system also includes a power-output device configured to be usable after sterilization, to interact with a power-receiving device connected to a handheld medical device, and configured to be carried by the health care provider proximate to a second body portion. If interacting, the received electrical or radiant power is transferred from the power-output device to the power-receiving device. The system further includes a wearable connective structure configured to be usable after sterilization, and to transfer the received electrical or radiant power from the power-receiving connector to the power-output device. | 11-17-2011 |
20110278957 | Wearable power source - Described embodiments include a system, an apparatus, and a method. A described system includes a portable energy source configured to supply electrical or radiant power and configured to be carried proximate to a first body portion of a health care provider. The system also includes a power-output connector configured to releasably couple with a power-receiving connector connected to a handheld medical device, the power-output connector configured to be carried proximate to a second body portion at a position distal of a shoulder joint of the health care provider. If coupled, the power-output connector and the power-receiving connector are operable to transfer the electrical or radiant power supplied by the portable energy source. The system further includes a connective structure configured to transfer the electrical or radiant power supplied by the portable energy source between the portable energy source and the power-output connector. | 11-17-2011 |
20110280922 | DEVICES AND METHODS FOR TREATING AND/OR PREVENTING DISEASES - The invention relates to a therapeutic device for the delivery of therapeutic agents, e.g. a peptide such as leuprolide, via the vagina to a female mammal. In some embodiments, the invention also relates to methods for the treatment of obesity and eating disorders, diabetes, multiple sclerosis (MS), endometriosis, uterine fibroids, polycystic ovarian disease, various cancers such as breast cancer, acne, hirsutism, microbial or fungal or viral infections such as bacterial vaginosis or AIDS/HIV, and chronic diseases using a disclosed vaginal device. | 11-17-2011 |
20110282415 | Wearable wireless power transmitter - Described embodiments include a system, an apparatus, and a method. A described system includes a portable power receiver configured to wirelessly receive electrical or radiant power from a wireless power transmitter source, and configured to be carried by a health care provider proximate to a first body portion of the health care provider. The system also includes a portable power-output device configured to interact with a power-receiving device connected to a handheld medical device, and configured to be carried by the health care provider proximate to a second body portion of the health care provider. If interacting, the electrical or radiant power is transferred from the portable power-output device to the power-receiving device. The system further includes a connective structure configured to transfer the electrical or radiant power between the portable power receiver and the portable power-output device. | 11-17-2011 |
20120089414 | Specialty Stents with flow control features or the like - Methods and systems are described for receiving a parameter relating to a specific patient and for configuring a stent with a flow occlusion portion in response to receiving the parameter relating to the specific patient. | 04-12-2012 |
20120109039 | Device, system, and method for controllably reducing inflammatory mediators in a subject - Devices, systems, and methods are provided for controlling an inflammatory response in a subject. Extracorporeal devices, systems, and methods are provided that alter the functional structure of one or more inflammatory mediators in the peripheral blood of the subject. The device or system is useful in a method for treating an inflammatory disease or condition in the subject. | 05-03-2012 |
20120136270 | Methods and Systems for Presenting an Inhalation Experience - Methods, computer program products, and systems are described that include detecting in an exhalant at least one indication of bioactive agent use by an individual and altering at least one artificial sensory experience at least partly based on the at least one indication of bioactive agent use by an individual. | 05-31-2012 |
20120195943 | Bone delivery device - Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects. | 08-02-2012 |
20120223293 | Biodegradable Electronic Devices - Biodegradable electronic devices may include a biodegradable semiconducting material and a biodegradable substrate layer for providing mechanical support to the biodegradable semiconducting material. | 09-06-2012 |
20120238944 | Device for Actively Removing a Target Cell from Blood or Lymph of a Vertebrate Subject - Devices, systems, and methods are described herein for controlling the level of one or more target cell types in the blood fluid and/or lymph fluid of a vertebrate subject. Devices, systems, and methods are provided that include a body defining at least one lumen configured for fluid flow; at least one controllable flow barrier to the at least one lumen; one or more sensor configured to detect one or more target cell types in blood fluid or lymph fluid of a vertebrate subject; at least one treatment region disposed within the at least one lumen; at least one reactive component disposed in the at least one treatment region; and at least one controller in communication with the one or more sensor and in communication with the at least one controllable flow barrier to the at least one lumen. | 09-20-2012 |
20120238945 | Device for Actively Removing a Target Cell from Blood or Lymph of a Vertebrate Subject - Devices, systems, and methods are described herein for controlling the level of one or more target cell types in the blood fluid and/or lymph fluid of a vertebrate subject. Devices, systems, and methods are provided that include a body defining at least one lumen configured for fluid flow; at least one controllable flow barrier to the at least one lumen; one or more sensor configured to detect one or more target cell types in blood fluid or lymph fluid of a vertebrate subject; at least one treatment region disposed within the at least one lumen; at least one reactive component disposed in the at least one treatment region; and at least one controller in communication with the one or more sensor and in communication with the at least one controllable flow barrier to the at least one lumen. | 09-20-2012 |
20120238948 | Device for Actively Removing a Target Cell from Blood or Lymph of a Vertebrate Subject - Devices, systems, and methods are described herein for controlling the level of one or more target cell types in the blood fluid and/or lymph fluid of a vertebrate subject. Devices and systems are provided that include a body defining at least one lumen configured for fluid flow; at least one controllable flow barrier to the at least one lumen; one or more sensor configured to detect one or more target cell types in blood fluid or lymph fluid of a vertebrate subject; at least one treatment region disposed within the at least one lumen; at least one reactive component disposed in the at least one treatment region; and at least one controller in communication with the one or more sensor and in communication with the at least one controllable flow barrier to the at least one lumen. | 09-20-2012 |
20120271228 | SUBSTANCE DELIVERY SYSTEM - Embodiments of a system including a remotely controlled substance delivery device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, a delivery device or related device may be placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. The concentration of a substance in the fluid to be delivered may be modified by a remote control signal. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used. | 10-25-2012 |
20120289943 | OSMOTIC PUMP WITH REMOTELY CONTROLLED OSMOTIC FLOW RATE - Embodiments of a system including a remotely controlled osmotic pump device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, an osmotic pump device is placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the osmotic pump device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used. | 11-15-2012 |
20130018665 | Specialty stents with flow control features or the likeAANM Jung; Edward K.Y.AACI BellevueAAST WAAACO USAAGP Jung; Edward K.Y. Bellevue WA USAANM Langer; RobertAACI NewtonAAST MAAACO USAAGP Langer; Robert Newton MA USAANM Leuthardt; Eric C.AACI St. LouisAAST MOAACO USAAGP Leuthardt; Eric C. St. Louis MO USAANM Levien; Royce A.AACI LexingtonAAST MAAACO USAAGP Levien; Royce A. Lexington MA USAANM Lord; Robert W.AACI SeattleAAST WAAACO USAAGP Lord; Robert W. Seattle WA USAANM Malamud; Mark A.AACI SeattleAAST WAAACO USAAGP Malamud; Mark A. Seattle WA USAANM Rinaldo, JR.; John D.AACI BellevueAAST WAAACO USAAGP Rinaldo, JR.; John D. Bellevue WA USAANM Tegreene; Clarence T.AACI BellevueAAST WAAACO USAAGP Tegreene; Clarence T. Bellevue WA USAANM Wood, JR.; Lowell L.AACI LivermoteAAST CAAACO USAAGP Wood, JR.; Lowell L. Livermote CA US - Methods and systems are described for obtaining a parameter relating to a stent inventory shortage and for specializing one or more stents in response to obtaining the parameter relating to the stent inventory shortage. | 01-17-2013 |
20130039966 | Bone Semi-Permeable Device - Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects. | 02-14-2013 |
20130101637 | Bone Semi-Permeable Device - Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects. | 04-25-2013 |
20130101638 | BONE SEMI-PERMEABLE DEVICE - Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects. | 04-25-2013 |
20130101639 | BONE SEMI-PERMEABLE DEVICE - Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects. | 04-25-2013 |
20130109934 | Device for Passively Removing a Target Component from Blood or Lymph of a Vertebrate Subject | 05-02-2013 |
20130112897 | Systems, devices, methods, and compositions including fluidized x-ray shielding compositions - Systems, devices, methods, and compositions are described for providing an x-ray shielding system including a flexible layer including a support structure having a plurality of interconnected interstitial spaces that provide a circulation network for an x-ray shielding fluid composition. | 05-09-2013 |
20130112898 | Systems, devices, methods, and compositions including fluidized x-ray shielding compositions - Systems, devices, methods, and compositions are described for providing an x-ray shielding system including a flexible layer including a support structure having a plurality of interconnected interstitial spaces that provide a circulation network for an x-ray shielding fluid composition. | 05-09-2013 |
20130112924 | Systems, devices, methods, and compositions including fluidized x-ray shielding compositions - Systems, devices, methods, and compositions are described for providing an x-ray shielding system including a flexible layer including a support structure having a plurality of interconnected interstitial spaces that provide a circulation network for an x-ray shielding fluid composition. | 05-09-2013 |
20130131627 | Device for Passively Removing a Target Component from Blood or Lymph of a Vertebrate Subject - Devices, systems, and methods are described herein for controlling or modulating the levels of one or more target components in the blood and/or lymph of a vertebrate subject. Devices and systems are provided that include a body defining at least one lumen configured for fluid flow; at least one controllable flow barrier to fluid flow into the at least one lumen; at least one first reservoir disposed within the body and configured to include one or more bifunctional tags, wherein the one or more bifunctional tags are configured to selectively bind to one or more target components in one or more of blood fluid or lymph fluid of a vertebrate subject; at least one treatment region disposed within the at least one lumen; and at least one second reservoir disposed in the at least one treatment region and configured to include one or more reactive components, wherein the one or more reactive components are configured to sequester the one or more bifunctional tags when bound to the one or more target components. | 05-23-2013 |
20130197417 | DEVICE, SYSTEM, AND METHOD FOR CONTROLLABLY REDUCING INFLAMMATORY MEDIATORS IN A SUBJECT - Devices, systems, and methods are provided for controlling an inflammatory response in a subject. Extracorporeal devices, systems, and methods are provided that alter the functional structure of one or more inflammatory mediators in the peripheral blood of the subject. The device or system is useful in a method for treating an inflammatory disease or condition in the subject. | 08-01-2013 |
20130234367 | Highly convertible endolumenal prostheses and methods of manufacture - Endolumenal prostheses that readily and extensively convert from a delivery configuration to a deployed configuration are disclosed. Endolumenal prostheses may be fabricated from one or more shape memory polymers, a high modulus elastomer, a polymer that is both elastomeric and exhibits shape memory behavior, a hydrogel, or some combination thereof. Polymers used to fabricate the prostheses are selectively synthesized to exhibit desired characteristics such as crystallinity, strain fixity rate, strain recovery rate, elasticity, tensile strength, mechanical strength, cross-linking density, extent physical cross-linking, extent of covalent cross-linking, extent of interpenetrating networks, rate of erosion, heat of fusion, crystallization temperature, and acidity during erosion. The endolumenal prostheses convert to the deployed configuration following delivery to a treatment site, upon exposure to an initiator either present within the body naturally or introduced into the body. | 09-12-2013 |
20130287688 | NOVEL COMPOSITIONS AND USES OF ANTI-HYPERTENSION AGENTS FOR CANCER THERAPY - Methods and compositions for improving the delivery and/or efficacy of a therapy (e.g., a cancer therapy) are disclosed. In one embodiment, methods and compositions for treating or preventing a cancer (e.g., a solid tumor such as a desmoplastic tumor) by administering to a subject an anti-hypertensive agent, as a single agent or in combination with a microenvironment modulator and/or a therapy, e.g., a cancer therapy (for example, a therapeutic agent or therapy, including immunotherapy (e.g., antibodies, vaccine, cell-based), nanotherapeutics, radiation therapy, photodynamic therapy, low molecular weight chemotherapeutics, molecularly targeted therapeutics and/or oxygen radical) are disclosed. | 10-31-2013 |
20130331792 | DEVICE AND USES THEREOF - The present disclosure provides devices and uses thereof. A devices disclosed herein comprises one or more tips, wherein the one or more tips are designed and constructed to initiate penetration by the device; and one or more protrusions in a region adjacent to each tip. In some embodiments, one or more protrusions can be constructed and arranged so that the required penetration force is reduced as compared with that observed for an otherwise identical device lacking the one or more protrusions. Additionally or alternatively, one or more protrusions can be constructed and arranged such that the required pull-out force is increased as compared with that observed for an otherwise identical device lacking the one or more protrusions. | 12-12-2013 |
20130338768 | BREAST IMPLANT WITH ANALYTE SENSORS AND INTERNAL POWER SOURCE - Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; a plurality of sensor modules attached to the shell, the sensor modules oriented to detect one or more analytes in a fluid adjacent to the shell, the sensor modules positioned at a distance from each other, wherein each of the plurality of sensor modules includes a unique identifier; and at least one power source operably attached to the plurality of sensor modules. | 12-19-2013 |
20130338769 | BREAST IMPLANT WITH ANALYTE SENSORS RESPONSIVE TO EXTERNAL POWER SOURCE - Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the plurality of sensor modules oriented to detect one or more analytes in a fluid adjacent to the shell, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source. | 12-19-2013 |
20130338770 | BREAST IMPLANT WITH COVERING, ANALYTE SENSORS AND INTERNAL POWER SOURCE - Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; at least one fluid-permeable cover, the cover completely enveloping the shell; a plurality of sensor modules attached to the shell, the sensor modules oriented to detect one or more analytes in a fluid between the shell and the cover, the sensor modules positioned at a distance from each other, wherein each of the plurality of sensor modules includes a unique identifier; and at least one power source operably attached to the plurality of sensor modules. | 12-19-2013 |
20130338771 | BREAST IMPLANT WITH COVERING AND ANALYTE SENSORS RESPONSIVE TO EXTERNAL POWER SOURCE - Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; at least one fluid-permeable cover, the cover completely enveloping the shell; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the sensor modules oriented to detect one or more analytes in a fluid between the shell and the cover, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source. | 12-19-2013 |
20130338772 | BREAST IMPLANT WITH REGIONALIZED ANALYTE SENSORS AND INTERNAL POWER SOURCE - Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; a plurality of projections extending from an external surface of the shell, the projections forming a plurality of compartments adjacent to the external surface of the shell; at least one fluid-permeable cover attached to the projections, the cover completely enveloping the shell and the plurality of projections; a plurality of sensor modules attached to the shell, each of the sensor modules oriented to detect one or more analytes in a fluid within one of the plurality of compartments, wherein each of the plurality of sensor modules includes a unique identifier; and at least one power source operably attached to the plurality of sensor modules. | 12-19-2013 |
20130338773 | BREAST IMPLANT WITH REGIONALIZED ANALYTE SENSORS RESPONSIVE TO EXTERNAL POWER SOURCE - Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; a plurality of projections extending from an external surface of the shell, the projections forming a plurality of compartments adjacent to the external surface of the shell; at least one fluid-permeable cover attached to the projections, the cover completely enveloping the shell and the plurality of projections; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the sensor modules oriented to detect one or more analytes in a fluid within one of the plurality of compartments, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source. | 12-19-2013 |
20140039451 | DEVICES AND METHODS FOR WEARABLE INJECTION GUIDES - Wearable injection guides and manufacture and use thereof are described, which include: a rigid material formed to substantially conform in shape to a topography of a body region of an individual, the rigid material substantially impenetrable to an injection needle, and the rigid material including one or more injection needle access regions arranged in a treatment pattern. | 02-06-2014 |
20140039452 | DEVICES AND METHODS FOR WEARABLE INJECTION GUIDES - Wearable injection guides and manufacture and use thereof are described, which include: a rigid needle-penetrable material having an inner surface and an outer surface, the inner surface having form-fitting contours substantially conforming to a topography of a body region of an individual and the outer surface including one or more fiducials indication of at least one treatment parameter. | 02-06-2014 |
20140039658 | SYSTEMS AND METHODS FOR WEARABLE INJECTION GUIDES - Systems and methods for wearable injection guides are described, which include: acquiring one or more digital images of a body region of an individual with at least one image capture device; creating a digitally rendered model of a wearable injection guide from the one or more digital images of the body region of the individual; adding one or more digitally rendered fiducials indicative of at least one treatment parameter to the digitally rendered model of the wearable injection guide; and forming the wearable injection guide from the digitally rendered model of the wearable injection guide, the formed wearable injection guide including one or more fiducials corresponding to the one or more digitally rendered fiducials on the digitally rendered model of the wearable injection guide. | 02-06-2014 |
20140088717 | ARTIFICIAL JOINT COMPONENTS INCLUDING SYNOVIAL FLUID DEFLECTING STRUCTURES - Artificial joint prosthetic components including synovial fluid deflection structures are described. Embodiments of artificial joint prosthesis include those with: a bone-facing surface of a artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis; and at least one fluid deflection structure positioned on the non-contact surface, the fluid deflection structure positioned to deflect synovial fluid away from the bone-prosthesis interface in vivo. | 03-27-2014 |
20140088718 | ARTIFICIAL JOINT COMPONENTS INCLUDING SYNOVIAL FLUID DEFLECTING STRUCTURES AND PARTICLE RETAINING STRUCTURES - Artificial joint prostheses, including hip, knee and shoulder joints, are described. In some aspects, an artificial joint prosthesis includes: a bone-facing surface of an artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis, the non-contact surface adjacent to the bone-facing surface of the artificial joint prosthesis; at least one fluid deflection structure attached to the non-contact surface, the fluid deflection structure positioned to direct a flow of synovial fluid away from the bone-prosthesis interface in vivo; and at least one particle retaining structure positioned to contact the directed flow of synovial fluid and configured to retain particles present within the synovial fluid. | 03-27-2014 |
20140088719 | ARTIFICIAL JOINT COMPONENTS INCLUDING MECHANIZED SYNOVIAL FLUID DEFLECTING STRUCTURES - Prosthetic artificial joints are described, including hip, knee and shoulder joints. In some embodiments, a artificial joint prosthesis includes: a bone-facing surface of a artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis, the non-contact surface adjacent to the bone-facing surface of the artificial joint prosthesis; at least one fluid deflection structure positioned adjacent to the non-contact surface, the fluid deflection structure positioned to deflect synovial fluid away from the bone-prosthesis interface in vivo; and a mechanism attached to the fluid deflection structure, the mechanism operable to move the fluid deflection structure to direct synovial fluid away from the bone-prosthesis interface in vivo. | 03-27-2014 |
20140088720 | ARTIFICIAL JOINT COMPONENTS INCLUDING MECHANIZED SYNOVIAL FLUID DEFLECTING STRUCTURES AND PARTICLE RETAINING STRUCTURES - Prosthetic artificial joints are described, including hip, knee and shoulder joints. In some embodiments, an artificial joint prosthesis includes: a bone-facing surface of a artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis, the non-contact surface adjacent to the bone-facing surface of the artificial joint prosthesis; at least one fluid deflection structure positioned adjacent to the non-contact surface, the fluid deflection structure positioned to deflect synovial fluid away from the bone-prosthesis interface in vivo; a mechanism attached to the fluid deflection structure, the mechanism operable to move the fluid deflection structure to direct synovial fluid away from the bone-prosthesis interface in vivo; and at least one particle retaining structure positioned to contact the directed flow of synovial fluid and configured to retain non-physiological particles present within the synovial fluid. | 03-27-2014 |
20140088721 | ARTIFICIAL JOINT COMPONENTS INCLUDING INTEGRAL MAGNETIC FIELDS CONFIGURED TO DEFLECT WEAR DEBRIS PARTICLES - Prosthetic artificial joints are described, including hip, knee and shoulder joints. In some embodiments, an artificial joint prosthesis includes: a bone-facing surface of a artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a first component of the artificial joint prosthesis including a contact surface of the artificial joint prosthesis, the first component fabricated from at least one polymer and a plurality of magnetic particles; and a second component of the artificial joint prosthesis including at least one magnet configured to create a magnetic field within the artificial joint, the at least one magnet positioned to form a magnetic field directed to influence a location of debris including the magnetic particles in the joint to a position distinct from the bone-prosthesis interface in vivo. | 03-27-2014 |
20140121636 | SYSTEMS AND METHODS FOR GUIDING INJECTIONS - Systems and methods are described herein for guided injection, which include: one or more controllable light-emitting elements configured to emit non-destructive light and a computing device operably connected to the one or more controllable light-emitting elements configured to emit non-destructive light, the computing device including a processor operable to receive at least one digital representation of a body region of an individual, the body region of the individual including one or more physical registration landmarks, the at least one digital representation including one or more digitally registered injection sites and one or more digital registration landmarks corresponding to the one or more physical registration landmarks on the body region; and control the one or more controllable light-emitting elements to illuminate a location of a surface of the body region of the individual corresponding in location to at least one of the one or more digitally registered injection sites. | 05-01-2014 |
20140121637 | SYSTEMS AND METHODS FOR GENERATING AN INJECTION GUIDE - System and methods are described herein for generating an injection guide, which include receiving one or more digital images of a body region of an individual, the body region including one or more physical registration landmarks, generating at least one digital representation of the body region using the one or more digital images, the at least one digital representation including one or more digital registration landmarks corresponding to the one or more physical registration landmarks on the body region, adding one or more digitally registered injection sites to the at least one digital representation of the body region in an injection-treatment pattern, the one or more digitally registered injection sites registered relative to the one or more digital registration landmarks, and generating one or more output signals having information for controlling one or more controllable light-emitting elements to illuminate a location on a surface of the body region of the individual corresponding in location to at least one of the one or more digitally registered injection sites. | 05-01-2014 |
20140139652 | PULSED PROJECTION SYSTEM FOR 3D VIDEO - A 3D-display system alternates between directing light representing a left-eye view of a 3D image to a viewer's left eye and directing light representing a right-eye view of a 3D image to a viewer's right eye. To direct the light towards the viewer's eyes, the system receives eye-location data relative to a display device from an eye-tracking system and uses light deflectors, such as acousto-optic, electro-optic, and passive optical deflectors, to aim the light in a particular direction. | 05-22-2014 |
20140220346 | MODULAR POLYMER HYDROGEL NANOPARTICLES AND METHODS OF THEIR MANUFACTURE - In certain embodiments, a nano-sized vehicle (e.g., a nanogel comprising nanoparticles) is provided herein for drug delivery with tunable biodistribution, low toxicity, and degradability, and with demonstrated targeting to bone. The composition is useful, for example, in the treatment of bone disease, particularly bone metastases from cancers such as breast, prostate, or lung cancer. | 08-07-2014 |
20140243995 | STACKED PLANAR SHEET TISSUE ENGINEERING SCAFFOLDS WITH 3D STRUCTURAL ORDER - A three-dimensional tissue engineering scaffold device and related methods are disclosed herein. The tissue engineering scaffold includes a plurality of polymers sheets. Each polymer sheet includes a plurality of micro-scale pores defined through the polymer sheet. The polymer sheets of the tissue engineering scaffold are aligned and stacked such that some of the pores of neighboring sheets are offset along at least one axis of the pores. The offset pores create features within the tissue engineering scaffold. In some implementations, the tissue engineering scaffold device is seeded with cells. In certain implementations, the tissue engineering scaffold is either implanted into a patient or used to grow functional tissue ex vivo. | 08-28-2014 |
20140257496 | ARTIFICIAL JOINT COMPONENTS INCLUDING SYNOVIAL FLUID DEFLECTING STRUCTURES AND PARTICLE RETAINING STRUCTURES - Artificial joint prostheses, including hip, knee and shoulder joints, are described. In some aspects, an artificial joint prosthesis includes: a bone-facing surface of an artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis, the non-contact surface adjacent to the bone-facing surface of the artificial joint prosthesis; at least one fluid deflection structure attached to the non-contact surface, the fluid deflection structure positioned to direct a flow of synovial fluid away from the bone-prosthesis interface in vivo; and at least one particle retaining structure positioned to contact the directed flow of synovial fluid and configured to retain particles present within the synovial fluid. | 09-11-2014 |
20140257497 | ARTIFICIAL JOINT COMPONENTS INCLUDING MECHANIZED SYNOVIAL FLUID DEFLECTING STRUCTURES - Prosthetic artificial joints are described, including hip, knee and shoulder joints. In some embodiments, a artificial joint prosthesis includes: a bone-facing surface of a artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis, the non-contact surface adjacent to the bone-facing surface of the artificial joint prosthesis; at least one fluid deflection structure positioned adjacent to the non-contact surface, the fluid deflection structure positioned to deflect synovial fluid away from the bone-prosthesis interface in vivo; and a mechanism attached to the fluid deflection structure, the mechanism operable to move the fluid deflection structure to direct synovial fluid away from the bone-prosthesis interface in vivo. | 09-11-2014 |
20140257498 | ARTIFICIAL JOINT COMPONENTS INCLUDING MECHANIZED SYNOVIAL FLUID DEFLECTING STRUCTURES AND PARTICLE RETAINING STRUCTURES - Prosthetic artificial joints are described, including hip, knee and shoulder joints. In some embodiments, an artificial joint prosthesis includes: a bone-facing surface of a artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis, the non-contact surface adjacent to the bone-facing surface of the artificial joint prosthesis; at least one fluid deflection structure positioned adjacent to the non-contact surface, the fluid deflection structure positioned to deflect synovial fluid away from the bone-prosthesis interface in vivo; a mechanism attached to the fluid deflection structure, the mechanism operable to move the fluid deflection structure to direct synovial fluid away from the bone-prosthesis interface in vivo; and at least one particle retaining structure positioned to contact the directed flow of synovial fluid and configured to retain non-physiological particles present within the synovial fluid. | 09-11-2014 |
20140277519 | ARTIFICIAL JOINT COMPONENTS INCLUDING SYNOVIAL FLUID DEFLECTING STRUCTURES - Artificial joint prosthetic components including synovial fluid deflection structures are described. Embodiments of artificial joint prosthesis include those with: a bone-facing surface of a artificial joint prosthesis, the bone-facing surface configured to face a bone-prosthesis interface in vivo; a non-contact surface of the artificial joint prosthesis; and at least one fluid deflection structure positioned on the non-contact surface, the fluid deflection structure positioned to deflect synovial fluid away from the bone-prosthesis interface in vivo. | 09-18-2014 |
20140288647 | BREAST IMPLANT WITH REGIONALIZED ANALYTE SENSORS RESPONSIVE TO EXTERNAL POWER SOURCE - Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; a plurality of projections extending from an external surface of the shell, the projections forming a plurality of compartments adjacent to the external surface of the shell; at least one fluid-permeable cover attached to the projections, the cover completely enveloping the shell and the plurality of projections; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the sensor modules oriented to detect one or more analytes in a fluid within one of the plurality of compartments, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source. | 09-25-2014 |
20140296663 | BREAST IMPLANT WITH COVERING AND ANALYTE SENSORS RESPONSIVE TO EXTERNAL POWER SOURCE - Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; at least one fluid-permeable cover, the cover completely enveloping the shell; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the sensor modules oriented to detect one or more analytes in a fluid between the shell and the cover, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source. | 10-02-2014 |
20140296978 | BREAST IMPLANT WITH REGIONALIZED ANALYTE SENSORS AND INTERNAL POWER SOURCE - Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; a plurality of projections extending from an external surface of the shell, the projections forming a plurality of compartments adjacent to the external surface of the shell; at least one fluid-permeable cover attached to the projections, the cover completely enveloping the shell and the plurality of projections; a plurality of sensor modules attached to the shell, each of the sensor modules oriented to detect one or more analytes in a fluid within one of the plurality of compartments, wherein each of the plurality of sensor modules includes a unique identifier; and at least one power source operably attached to the plurality of sensor modules. | 10-02-2014 |
20140303605 | ACTIVE TREMOR CONTROL IN SURGICAL INSTRUMENTS RESPONSIVE TO A PARTICULAR USER - Described embodiments include a method. The method includes initiating a hand tremor characterization mode of a handheld or hand operated surgical instrument having a working tip. The method includes detecting a hand tremble motion imparted by a user during the characterization mode. The method includes recognizing a pattern in the detected hand tremble motion and saving the recognized pattern in a computer storage media. The method includes initiating a hand tremor suppression mode of the surgical instrument. The method includes detecting a hand tremble motion in the surgical instrument imparted by a user during the suppression mode. The method includes retrieving the recognized pattern from the computer storage media. The method includes stabilizing the working tip by activating an actuator, the activation responsive to the recognized pattern and to the detected user-imparted hand tremble motion during the suppression mode. | 10-09-2014 |
20140303660 | ACTIVE TREMOR CONTROL IN SURGICAL INSTRUMENTS - Described embodiments include a handheld or hand operated surgical instrument. The instrument includes an elongated member having a longitudinal axis and a handle portion. The instrument includes a working tip coupled to the elongated member. The instrument includes a sensor configured to detect a user-imparted hand tremble motion. The instrument includes a flexible beam element of the elongated member located in-between the handle portion and the working tip, and configured to reversibly bend, extend, or rotate with respect to the longitudinal axis. The instrument includes an actuator physically coupled to the flexible beam element and configured to reversibly bend, extend, or rotate the flexible beam element with respect to the longitudinal axis. The instrument includes a controller configured to stabilize the working tip by activating the actuator in a manner responsive to the detected user-imparted hand tremble motion in at least one degree of freedom. | 10-09-2014 |
20140312135 | ODORANT-RELEASING UTENSIL - In an aspect, an eating utensil includes a controllable odorant emitter for delivering an odorant to a person who is eating or drinking from the eating utensil. The odorant may be delivered orthonasally or retronasally. The odorant may be used to stimulate or suppress appetite. In an aspect, a controllable odorant emitter is provided in an attachment that may be removably secured to an eating utensil. Related methods and systems for delivering odorant in connection with use of an eating utensil are described. | 10-23-2014 |
20150064146 | Blood Brain Barrier Device - Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects. | 03-05-2015 |