Patent application number | Description | Published |
20120095287 | IMAGING AND EVALUATING EMBRYOS, OOCYTES, AND STEM CELLS - Methods, compositions and kits for determining the developmental potential of one or more embryos or pluripotent cells and/or the presence of chromosomal abnormalities in one or more embryos or pluripotent cells are provided. These methods, compositions and kits find use in identifying embryos and oocytes in vitro that are most useful in treating infertility in humans. | 04-19-2012 |
20130162795 | IMAGING AND EVALUATING EMBRYOS, OOCYTES, AND STEM CELLS - Methods, compositions and kits for determining the developmental potential of one or more embryos or pluripotent cells and/or the presence of chromosomal abnormalities in one or more embryos or pluripotent cells are provided. These methods, compositions and kits find use in identifying embryos and oocytes in vitro that are most useful in treating infertility in humans. | 06-27-2013 |
20130165745 | IMAGING AND EVALUATING EMBRYOS, OOCYTES, AND STEM CELLS - Methods, compositions and kits for determining the developmental potential of one or more embryos or pluripotent cells and/or the presence of chromosomal abnormalities in one or more embryos or pluripotent cells are provided. These methods, compositions and kits find use in identifying embryos and oocytes in vitro that are most useful in treating infertility in humans. | 06-27-2013 |
20130184518 | MECHANICAL BIOMARKERS FOR OOCYTE AND EMBRYO VIABILITY - Provided are methods for the determination of the viability of a mammalian embryo or a potential embryo generated from a mammalian oocyte, comprising applying a mechanical stimulus to the embryo or oocyte, detecting a temporal response of the embryo or oocyte to the mechanical stimulus, and deriving measurements for one or more parameters from the temporal response, the measurements being indicative of viability. Also provided are methods for selecting an embryo for transfer and methods for enhancing the viability of an embryo or oocyte. | 07-18-2013 |
20130225431 | ASSESSMENT OF CELLULAR FRAGMENTATION DYNAMICS FOR DETECTION OF HUMAN EMBRYONIC ANEUPLOIDY - Methods of evaluating the developmental potential of human embryos are disclosed. In particular, the invention relates to methods of detecting embryonic aneuploidy by assessment of cellular fragmentation dynamics in individual blastomeres of embryos up to the 4-cell stage. The methods of the invention should improve in vitro fertilization (IVF) outcomes by reducing inadvertent transfer of non-viable embryos likely to result in spontaneous miscarriage. | 08-29-2013 |
20140349334 | NON-INVASIVE IMAGING TO THE BLASTOCYST STAGE FOR THE DETECTION OF HUMAN EMBRYONIC ANEUPLOIDY - Methods are provided for the non-invasive imaging of embryos to determine whether they are euploid or aneuploid. | 11-27-2014 |
20160109428 | MECHANICAL BIOMARKERS FOR OOCYTE AND EMBRYO VIABILITY - Provided are methods for the determination of the viability of a mammalian embryo or a potential embryo generated from a mammalian oocyte, comprising applying a mechanical stimulus to the embryo or oocyte, detecting a temporal response of the embryo or oocyte to the mechanical stimulus, and deriving measurements for one or more parameters from the temporal response, the measurements being indicative of viability. Also provided are methods for selecting an embryo for transfer and methods for enhancing the viability of an embryo or oocyte. | 04-21-2016 |
20160137975 | GENERATION OF MALE GERM CELLS - Methods are provided for the generation of male germ cells from somatic cells. Included are methods of non-integrative reprogramming for germ cell differentiation with a reduced risk of neoplasia during in vivo differentiation by the inclusion of VASA with the reprogramming factors. Also included are methods of generating male germ cells from reprogrammed pluripotent cells by direct injection of the reprogrammed cells into the seminiferous tubules. In some embodiments the somatic cells are derived from a male with oligospermia or azoospermia, which may be the result of a genetic abnormality in Azoospermia Factor (AZF) region. | 05-19-2016 |