Patent application number | Description | Published |
20090093972 | Meter Having Multi-Level User Interface - A meter adapted to determine and store an analyte concentration reading, in particular a glucose concentration reading, and including an interface having a plurality of predefined levels of user features. The predefined levels may be selected by a user based on the user's preferences, needs and abilities. | 04-09-2009 |
20090156923 | Meter Having Post-Meal Test-Time Alarm - A method for using a meter and a meter ( | 06-18-2009 |
20100041083 | METER ADAPTED TO SIMULTANEOUSLY DISPLAY THE NUMBER OF HIGH, LOW AND TOTAL TEST RESULTS - A meter adapted for evaluating, saving and simultaneously displaying the number of analyte concentration readings that are greater than a first predetermined analyte concentration level, the number of analyte concentration readings that are less than a second predetermined analyte concentration level and the total number of analyte concentration readings over a predetermined time interval. | 02-18-2010 |
20110137571 | METER HAVING MULTI-LEVEL USER INTERFACE - A meter adapted to determine and store an analyte concentration reading, in particular a glucose concentration reading, and including an interface having a plurality of predefined levels of user features. The predefined levels may be selected by a user based on the user's preferences, needs and abilities. | 06-09-2011 |
Patent application number | Description | Published |
20080208998 | SYSTEM AND METHOD FOR IMPROVED SYNCHRONIZATION BETWEEN A SERVER AND A CLIENT - A system and method for improved client and server communications, more particularly, an improved protocol that may be used for communication between a client and a server, such as in an email environment. Many features are provided for improved communications. An email server may provide the best message body available for an email message, may transfer an entire data object if requested property or properties are not well defined within the data object, may provide progress data for use in tracking download progress, and may send error information for a data object having an error. Email changes may be optimized at an email server component, even if the email changes occurred at another email server component. An email server may maintain a table of changes that occur to folders at an associated data store, and may notify a subscribed email client component of changes that occur in the table. | 08-28-2008 |
20110161448 | System and Method for Improved Synchronization Between a Server and a Client - A system and method for improved client and server communications, more particularly, an improved protocol that may be used for communication between a client and a server, such as in an email environment. Many features are provided for improved communications. An email server may provide the best message body available for an email message, may transfer an entire data object if requested property or properties are not well defined within the data object, may provide progress data for use in tracking download progress, and may send error information for a data object having an error. Email changes may be optimized at an email server component, even if the email changes occurred at another email server component. An email server may maintain a table of changes that occur to folders at an associated data store, and may notify a subscribed email client component of changes that occur in the table. | 06-30-2011 |
20120209928 | SYSTEM AND METHOD FOR IMPROVED SYNCHRONIZATION BETWEEN A SERVER AND A CLIENT - A system and method for improved client and server communications, more particularly, an improved protocol that may be used for communication between a client and a server, such as in an email environment. Many features are provided for improved communications. An email server may provide the best message body available for an email message, may transfer an entire data object if requested property or properties are not well defined within the data object, may provide progress data for use in tracking download progress, and may send error information for a data object having an error. Email changes may be optimized at an email server component, even if the email changes occurred at another email server component. An email server may maintain a table of changes that occur to folders at an associated data store, and may notify a subscribed email client component of changes that occur in the table. | 08-16-2012 |
20130297709 | SYSTEM AND METHOD FOR IMPROVED SYNCHRONIZATION BETWEEN A SERVER AND A CLIENT - A system and method for improved client and server communications, more particularly, an improved protocol that may be used for communication between a client and a server, such as in an email environment. Many features are provided for improved communications. An email server may provide the best message body available for an email message, may transfer an entire data object if requested property or properties are not well defined within the data object, may provide progress data for use in tracking download progress, and may send error information for a data object having an error. Email changes may be optimized at an email server component, even if the email changes occurred at another email server component. An email server may maintain a table of changes that occur to folders at an associated data store, and may notify a subscribed email client component of changes that occur in the table. | 11-07-2013 |
Patent application number | Description | Published |
20100322777 | COMPRESSOR BLADE | 12-23-2010 |
20120163988 | GAS TURBINE ENGINE AIRFOIL SHAPED COMPONENT - A gas turbine engine airfoil shaped component is disclosed including in one form a compressor blade or vane having a tip portion capable of producing a relatively low pressure near the leading edge of the tip to induce a local jet of stream-wise momentum flow. In one form the tip portion includes a camber angle distribution that produces relatively large change in camber angle near the leading edge but relatively flat distribution for remainder of blade. In one form the tip portion includes relatively large change in camber angle near trailing edge. | 06-28-2012 |
20140255188 | GAS TURBINE ENGINE AIRFLOW MEMBER HAVING SPHERICAL END - A gas turbine engine airflow member is disclosed having spherical interface shapes at a tip end and a hub end. In one embodiment, the airflow member is a fan blade. The spherical interface shapes can be convex or concave. In one form, the tip end spherical shape is axially shifted aft relative to a hub end. The tip end can include relatively little forward portion in an expanding flow path with predominant portion of the tip end in a contracting flow path. Such a configuration can occur with a midpoint and trailing edge located in the contracting flow path. A center of gravity of a swept airflow member having spherical end shape can be located on a pivot axis of the airflow member. Divot depressions can be provided to permit concave flow path shapes. | 09-11-2014 |
20150016983 | SUBSONIC SHOCK STRUT - A gas turbine engine strut is disclosed as having a will forebody positioned upstream of a point of maximum thickness and an aft body positioned downstream of the point of maximum thickness. The aft body includes a discontinuity in a curvature distribution which provides for a “subsonic shock.” The discontinuity in curvature distribution can include in inflection point that marks a transition from a curvature associated with an upstream portion of the aft body to a second curvature associated with a downstream portion of the aft body. In some forms, the aft body can additionally include boundary layer aspiration. The gas turbine engine strut can be symmetrical about a centerline. | 01-15-2015 |
20150128604 | GAS TURBINE ENGINE FLOW PATH GEOMETRY - A flow path surface of a gas turbine engine at the location of a bladed component is disclosed in which the flow path surface includes a cylindrical upstream side and a conical downstream side. The bladed component is located at the intersection of the cylindrical upstream side and the conical downstream side. The cylindrical upstream side can extend from a leading edge of the bladed component, or a point upstream of it, to a location between the leading edge and trailing edge of the component. The conical downstream side can extend past the trailing edge of the bladed component. The bladed component can be a fan blade or a compressor blade. | 05-14-2015 |
Patent application number | Description | Published |
20150062909 | LED LAMP - A LED lamp includes an at least partially optically transmissive enclosure and a base. A LED assembly comprising at least one LED is located in the enclosure and is operable to emit light when energized through an electrical path from the base. A heat sink comprises a heat dissipating portion that is at least partially exposed to the ambient environment and a heat conducting portion that is thermally coupled to the at least one LED. The heat sink is connected to the base by a snap fit connector comprising a deformable first member on one of the base or heat sink engaging a second member on the other one of the heat sink and the base. A retention member holds the first member in engagement with the second member. A seal is positioned between the heat sink and the base, the seal being compressed between the heat sink and the base. | 03-05-2015 |
20150276138 | LED LAMP WITH LED BOARD BRACE - A LED lamp includes an elongated at least partially optically transmissive enclosure having a first end and a second end. LEDs are in the enclosure and are operable to emit light through the enclosure when energized through an electrical path. A first pin is mounted to the first end of the enclosure and a second pin mounted to the second end of the enclosure, the first pin and the second pin are in the electrical path. The LEDs are mounted on an LED board. A plurality of discrete braces are spaced along the length of the LED board and are mounted to the LED board. The braces support and position the LED board in the enclosure. | 10-01-2015 |
20150276139 | LED LAMP WITH LED BOARD BRACE - An enclosure is divided into first and second portions by a theoretical plane defined by a horizontal line. LEDs are mounted on an LED board in the enclosure and are operable to emit light when energized through an electrical path. A first pin is mounted to a first end of the enclosure and a second pin mounted to a second end of the enclosure, both pins being in the electrical path. Braces support the LED board and comprise first and second legs. The first leg and second leg extend to a first point and a second point of intersection of the plane and the internal surface of the enclosure, respectively. A first conductor connects the first pin to the LED board and a second conductor connects the second pin to the LED board. The first conductor and first pin and the second conductor and the second pin are one-piece. | 10-01-2015 |
20150276140 | LED LAMP - An LED lamp includes an elongated at least partially optically transmissive enclosure. The LEDs are mounted on an LED board. The enclosure has a support structure for supporting the LED board. The support structure is formed as one-piece with the enclosure and of an optical material. A pair of end caps are secured to the ends of the enclosure using a snap-fit connection. The end caps retain pins for connecting to a light fixture. | 10-01-2015 |
20150362168 | LED LAMP - A LED lamp comprises an enclosure containing a reflective surface and an optically transmissive exit surface and a base. A LED assembly is mounted on a submount, is located in the enclosure and is operable to emit light when energized through an electrical path from the base. The submount comprises a connector portion having a first electrical contact that is in the electrical path. A first spring contact is electrically coupled to lamp electronics where the lamp electronics and the first spring contact are in the electrical path. A heat sink comprises a heat dissipating portion that is at least partially exposed to the ambient environment and a heat conducting portion that is thermally coupled to the LED assembly. The connector portion is inserted into the heat sink such that the first electrical contact creates an electrical contact coupling with the first spring contact. | 12-17-2015 |
Patent application number | Description | Published |
20110133040 | SUSPENSION SYSTEM FOR MINIMALLY INVASIVE SURGERY - A suspension system for supporting surgical devices inside a patient's body cavity comprising an external frame, a plurality of elongated members extending from the external frame and through the patient's skin into the body cavity, and an internal platform located inside the body cavity. The internal platform includes a plurality of links reconfigurable from a first elongated position wherein the links are substantially aligned along a longitudinal axis for insertion to a second position wherein the links are angled with respect to one another to form a non-linear configuration. | 06-09-2011 |
20110313249 | ENDOLUMINAL CRAWLER - An endoluminal crawler used in endoscopic procedures includes a body and an actuation unit. The body includes a tubular portion. The actuation unit includes an actuator providing a rotational output and a traction belt. The traction belt includes a traction portion and an engaging portion. The traction portion protrudes out of a slot defined in the tubular portion and the engaging portion operatively engages the actuator. | 12-22-2011 |
20120108904 | CLEANER FOR ENDOSCOPE - A surgical scope for viewing a surgical site of a patient including an elongated tube, a viewing lens having an outer surface positioned at the distal portion of the scope, and a lens cleaner positioned at the distal portion and translatable between a first position and a second position. The lens cleaner includes an arcuate wiper having a complementary shape to the shape of the lens. An actuator is spaced proximally of the wiper and actuable to translate the wiper along the outer surface of the lens. | 05-03-2012 |
20120241188 | WIRE GUIDES AND ANCHORS FOR ENDOSCOPY - A wire guide system is provided for use during a endoscopic surgical procedures. The wire guide system includes a cylindrical shaft having a hollow chamber along a longitudinal axis of the cylindrical shaft, a flange fit disposed around the cylindrical shaft and a seal disposed around the cylindrical shaft and abutting the flange. The system may also include an anchor affixed to the cylindrical shaft and having an aperture from which at least one of a sensor, a light, a camera, tissue and/or organs may be suspended therefrom and at least one cable extending from one end of the cylindrical shaft to another end of the cylindrical shaft through the hollow chamber. | 09-27-2012 |
20140135654 | WIRE GUIDES AND ANCHORS FOR ENDOSCOPY - A wire guide system is provided for use during a endoscopic surgical procedures. The wire guide system includes a cylindrical shaft having a hollow chamber along a longitudinal axis of the cylindrical shaft, a flange fit disposed around the cylindrical shaft and a seal disposed around the cylindrical shaft and abutting the flange. The system may also include an anchor affixed to the cylindrical shaft and having an aperture from which at least one of a sensor, a light, a camera, tissue and/or organs may be suspended therefrom and at least one cable extending from one end of the cylindrical shaft to another end of the cylindrical shaft through the hollow chamber. | 05-15-2014 |
Patent application number | Description | Published |
20110288930 | SERVICE FOR ACCEPTING AND SELECTIVELY EXPOSING USER-GENERATED LISTS - An interactive system enables users to generate and submit lists of items (e.g., products) for viewing by other users. The user-generated lists are selectively suggested to users of the system based on their respective behaviors, such as their item viewing activities, searches, and/or item purchases. The system may monitor the behaviors of users who access particular user-generated lists, and based on the monitored behaviors, generate measures of the effectiveness of particular lists (e.g., effectiveness at driving item purchases). The measures of effectiveness may be considered in selecting particular lists to suggest. | 11-24-2011 |
20130151370 | SERVICE FOR ACCEPTING AND SELECTIVELY EXPOSING USER-GENERATED LISTS - An interactive system enables users to generate and submit lists of items (e.g., products selected from an electronic catalog) for viewing by other users. The user-generated lists are selectively suggested to users of the system based (or based in part) on ratings of the user-generated lists. These ratings may, for example, be based on explicit ratings of the lists by users, and/or measures of how effective the respective lists are at driving purchases of items. In some contexts, the system may select one or more user-generated lists to present to a user based on a set of items purchased, viewed, or otherwise selected by the user, or based on the results of a search query submitted by the user. | 06-13-2013 |
Patent application number | Description | Published |
20090265713 | PROACTIVE CORRECTION ALERTS - Computerized methods and systems for creating and documenting protocol orders in a molecular diagnostic laboratory environment are provided. Utilizing the methods and systems described herein, protocol statements may require values to be entered in association therewith prior to permitting access to subsequent protocol orders. Accordingly, more accurate test runs and, consequently, more accurate test results, may be achieved. Additionally, as values associated with protocol statements are electronically captured, in accordance with embodiments hereof, such values may be searched to evaluate trends or identify protocol orders and/or results that may be affected by a later discovered error or the like. | 10-22-2009 |
20100004946 | SHARED PROTOCOL STATEMENTS - Computerized methods and systems for creating and documenting protocol orders in a molecular diagnostic laboratory environment are provided. Utilizing the methods and systems described herein, protocol statements may require values to be entered in association therewith prior to permitting access to subsequent protocol orders. Accordingly, more accurate test runs and, consequently, more accurate test results, may be achieved. Additionally, as values associated with protocol statements are electronically captured, in accordance with embodiments hereof, such values may be searched to evaluate trends or identify protocol orders and/or results that may be affected by a later discovered error or the like. | 01-07-2010 |
20130275361 | ASSOCIATING MULTIPLE DATA SOURCES INTO A WEB-ACCESSIBLE FRAMEWORK - Systems, methods, and computer-readable media for associating multiple data sources into a web-accessible framework. Health data is received from multiple data sources and is used to populate a framework comprising at least one topic focused data mart. Each topic focused data mart has a common structure and is associated with a web service providing standard features supported by each topic focused data mart and custom features specific to a topic associated with each topic focused data mart. In various embodiments, demographic information is received from a clinician and is utilized to present context-specific data derived from the topic focused data mart. | 10-17-2013 |
20150019253 | INTEGRATED DATA CAPTURE USING ALIASING SCHEMES - Methods, systems, and computer-storage media are provided for using a generic aliasing scheme to facilitate electronic transcription of groups of clinical event data extracted from an electronic medical record to case report forms associated with clinical studies. The generic aliasing scheme is also used to electronically transcribe documentation of task completion to case report forms associated with the clinical studies. | 01-15-2015 |
20150032475 | STORING AND DISTRIBUTING PERSONAL GRID RESULTS IN A CLINICAL SETTING - Methods and systems are provided for the communication of personal grid results in a clinical setting. Personal grid results comprise one or more of: 1.) genetic sequences or genetic markers of a genome of the patient, 2.) one or more proteomic profiles of the patient, 3.) one or more genetic sequences or genetic markers of a microbiome of the patient, 4.) one or more transcriptome profiles of the patient, 5.) genetic sequences or genetic markers of a exome of the patient, and 6.) one or more cytogenetic data of the patient. The personal grid results also comprise clinical history, allergies, family history, a belief system, and attributes of the patient. The personal grid results are received by the entity that is responsible for distributing the personal grid results from a first party (or a publisher). The personal grid results are then communicated to a second party (or a subscriber) for a cost. In return, a royalty fee is paid to the first party (or publisher) by the entity responsible for distributing the personal grid results. | 01-29-2015 |
20160110525 | Integrated Data Capture Using Aliasing Schemes - Methods, systems, and computer-storage media are provided for using a generic aliasing scheme to facilitate electronic transcription of groups of clinical event data extracted from an electronic medical record to case report forms associated with clinical studies. The generic aliasing scheme is also used to electronically transcribe documentation of task completion to case report forms associated with the clinical studies. | 04-21-2016 |
Patent application number | Description | Published |
20110161207 | Biological Reagent Catalog - Embodiments relate to providing one or more recommended biological reagents in response to receiving a biological reagent order. An exemplary embodiment includes identifying biological reagents based on a biological reagent order that has been received. Characteristic data of the identified biological reagents may then be evaluated to identify a characteristic conflict among the identified biological reagents. Similarly, inventory data of the identified biological reagents may then be evaluated to identify an inventory conflict among the identified biological reagents. If a conflict, either characteristic or inventory, is identified, a recommendation for an alternative biological reagent may be provided that is free from conflict. Additionally, historical use data may be maintained and referenced to aid in identifying a biological reagent as either a potential biological reagent based on a suspected biological condition or as a substitute biological reagent. | 06-30-2011 |
20130332190 | PROVIDING INDICATIONS OF CLINICAL-TRIAL CRITERIA MODIFICATIONS - Systems and method for providing indications of trial-related attributes are provided. In embodiments, the method includes providing an indication to view a suggested clinical-trial criteria modification(s) that, if implemented, is expected to increase a number of patients eligible for a clinical trial. Thereafter, a suggested criterion modification for a clinical-trial criterion is received. The suggested criterion modification is based on a comparison of aggregated patient data associated with the clinical-trial criterion to the clinical-trial criterion. The indication of the suggested criterion modification for the clinical-trial criterion can be displayed. | 12-12-2013 |
20130332191 | IDENTIFYING PATIENT ELIGIBILITY FOR CLINICAL TRIALS - Systems and method for facilitating clinical-trial referrals are provided. In embodiments, the method includes searching clinical-trial data associated with a plurality of clinical trials to identify one or more clinical trials for which a patient is eligible to participate based on patient data associated with the patient. Such clinical-trial data associated with the plurality of clinical trials can be aggregated in a centralized data store. Thereafter, an indication of the one or more clinical trials for which the patient is eligible is provided. | 12-12-2013 |
20140122113 | PROVIDING INDICATIONS OF CLINICAL-TRIAL CRITERIA MODIFICATIONS - Systems and method for providing indications of trial-related attributes are provided. In embodiments, the method includes providing an indication to view a suggested clinical-trial criteria modification(s) that, if implemented, is expected to increase a number of patients eligible for a clinical trial. Thereafter, a suggested criterion modification for a clinical-trial criterion is received. The suggested criterion modification is based on a comparison of aggregated patient data associated with the clinical-trial criterion to the clinical-trial criterion. The indication of the suggested criterion modification for the clinical-trial criterion can be displayed. | 05-01-2014 |
Patent application number | Description | Published |
20130154224 | AXLE SUSPENSION SYSTEM - An axle suspension system for a vehicle. The axle suspension system may include an axle having an exterior surface and an axle wrap. The axle wrap may include a wrap portion, a cam bracket, and an actuator bracket. The wrap portion may engage the exterior surface. The cam bracket and actuator bracket may be spaced apart and may extend from the wrap portion. | 06-20-2013 |
20140232074 | TRAILER AXLE SUSPENSION SYSTEM AND A METHOD OF CONTROL - A trailer axle suspension system and a method of control. The trailer axle suspension system may be deflated when the trailer is approaching the dock and proximity of the trailer to the dock is within a predetermined limit. | 08-21-2014 |
20140232177 | AXLE ASSEMBLY AND A METHOD OF MANUFACTURE - An axle assembly and a method of manufacture. The axle assembly may have an axle tube that may be formed to increase a wall thickness of an end portion. A spindle may be fastened to the end portion with a fastener that is received in the fastener hole in the end portion. | 08-21-2014 |
20150059945 | Tire Inflation System Having a Passage for Routing Pressurized Gas Through a Hub - A tire inflation system having a conduit, a hub, and a seal assembly. The hub may be rotatably mounted on a spindle and may have a passage. The seal assembly may have a seal passage that fluidly connects the conduit to the passage. | 03-05-2015 |
20150059946 | Tire Inflation System with External Pressurized Gas Routing - A tire inflation system for a vehicle. The tire inflation system may include a gas supply subsystem that may supply pressurized gas to a tire via first conduit that may be connected to an axle shaft. | 03-05-2015 |
20150059947 | Tire Inflation System with Peristaltic Pump - A tire inflation system having a peristaltic pump. The peristaltic pump may output a pressurized gas when a flexible tube of the peristaltic pump rotates with a wheel end assembly about an axis. | 03-05-2015 |
20150075688 | Tire Inflation System with a Passage for Routing Pressurized Gas - A tire inflation system having a spindle that is configured to support a wheel bearing. A passage for routing pressurized gas may be provided with the spindle or with a sleeve that may be disposed on the spindle. | 03-19-2015 |
20150101723 | Tire Inflation System with Axle Driven Pump - A tire inflation system having a spindle, a pump actuating member, and a pump. The pump actuating member may actuate the pump when the pump rotates about an axis, thereby causing the pump to output a pressurized gas. | 04-16-2015 |
Patent application number | Description | Published |
20090253203 | Reprogramming a Cell by Inducing a Pluripotent Gene Through Use of a Small Molecule Modulator - The invention relate to methods, compositions, and kits for reprogramming a cell. In one embodiment, the invention relates to a method comprising inducing the expression of at least one gene that contributes to a cell being pluripotent or multipotent. In yet another embodiment, the method comprises exposing a cell to a small molecule modulator that induces the expression of at least one gene that contributes to a cell being pluripotent or multipotent. In yet another embodiment, the invention relates to a reprogrammed cell and an enriched population of reprogrammed cells that can have characteristics of an ES-like cell can be re- or trans-differentiated into various differentiated cell types. | 10-08-2009 |
20090269763 | Reprogramming a cell by inducing a pluripotent gene through RNA interference - The invention relate to methods, compositions, and kits for reprogramming a cell. In one embodiment, the invention relates to a method for inducing the expression of at least one gene that contributes to a cell being pluripotent or multipotent. In yet another embodiment, the method comprises inhibiting the expression of a gene that codes for a protein involved in transcriptional repression. In yet another embodiment, the invention relates to a reprogrammed cell or an enriched population of reprogrammed cells that can have characteristics of an ES-like cell, which can be re- or trans-differentiated into a differentiated cell type. | 10-29-2009 |
20090275032 | Reprogramming a cell by inducing a pluripotent gene through use of an HDAC modulator - The invention relate to methods, compositions, and kits for reprogramming a cell. In one embodiment, the invention relates to a method comprising inducing the expression of at least one gene that contributes to a cell being pluripotent or multipotent. In yet another embodiment, the method comprises inhibiting the activity of an HDAC with an HDAC inhibitor and inducing the expression of at least one gene that contributes to a cell being pluripotent or multipotent. In still another embodiment, the invention relates to a method for reprogramming comprising exposing a cell to more than one agent to inhibit more than ore type of regulatory protein. In yet another embodiment, the invention relates to a reprogrammed cell or an enriched population of reprogrammed cells that can have characteristics of an ES-like cell, which can be re- or trans-differentiated into various differentiated cell types | 11-05-2009 |
20110059526 | REPROGRAMMING A CELL BY INDUCING A PLURIPOTENT GENE THROUGH USE OF AN HDAC MODULATOR - The invention relate to methods, compositions, and kits for reprogramming a cell. In one embodiment, the invention relates to a method comprising inducing the expression of at least one gene that contributes to a cell being pluripotent or multipotent. In yet another embodiment, the method comprises inhibiting the activity of an HDAC with an HDAC inhibitor and inducing the expression of at least one gene that contributes to a cell being pluripotent or multipotent. In still another embodiment, the invention relates to a method for reprogramming comprising exposing a cell to more than one agent to inhibit more than ore type of regulatory protein. In yet another embodiment, the invention relates to a reprogrammed cell or an enriched population of reprogrammed cells that can have characteristics of an ES-like cell, which can be re- or trans-differentiated into various differentiated cell types | 03-10-2011 |
20120322153 | REPROGRAMMING A CELL BY ACTIVATION OF THE ENDOGENOUS TRANSCRIPTION FACTOR NETWORK - The invention relate to methods, compositions, and kits for reprogramming a cell. In one embodiment, the invention relates to a method comprising inducing the expression of at least one gene that contributes to a cell being pluripotent or multipotent. In yet another embodiment, the method comprises delivering a transcription factor to a cell and exposing said cell to an agent that inhibits the activity, expression, or activity and expression of a gene, which codes for a protein, or a protein involved in transcriptional repression, and selecting a cell, wherein differentiation potential has been restored to said cell. In yet another embodiment, the invention relates to a reprogrammed cell and an enriched population of reprogrammed cells that can have characteristics of an ES-like cell can be re- or trans-differentiated into various differentiated cell types. | 12-20-2012 |
Patent application number | Description | Published |
20080286382 | COMPOSITIONS AND METHODS FOR ESTABLISHING AND/OR MAINTAINING PREGNANCY - The present invention relates to compositions comprising selenium (e.g., organic selenium (e.g., selenized yeast (e.g., SEL-PLEX))) and methods of using the same (e.g., as a therapeutic and/or prophylactic treatment). For example, the present invention provides compositions comprising selenium (e.g., organic selenium (e.g., selenized yeast (e.g., SEL-PLEX))) and methods of using the same for treating and/or preventing one or more conditions (e.g., problems) disorders, and/or diseases related to establishing and/or maintaining a pregnancy. Compositions and methods of the present invention find use in, among other things, research and clinical (e.g., preventative and therapeutic) applications. | 11-20-2008 |
20100247679 | METHODS AND COMPOSITIONS FOR ALTERING CELL FUNCTION - The present invention relates to compositions and methods for altering cell function. In particular, the present invention provides compositions comprising selenium (e.g., SEL-PLEX) and methods of using the same (e.g., as a therapeutic and/or prophylactic treatment). Additionally, the present invention demonstrates that specific forms of selenium (e.g., SEL-PLEX), when administered to a subject, possess the ability to alter (e.g., reduce) gene expression in various tissues (e.g., compared to expression in subjects not administered selenium). | 09-30-2010 |
20110008466 | METHODS AND COMPOSITIONS FOR ALTERING CELL FUNCTION - The present invention relates to compositions and methods for altering cell function. In particular, the present invention provides compositions comprising selenium (e.g., SEL-PLEX) and methods of using the same (e.g., as a therapeutic and/or prophylactic treatment). Additionally, the present invention demonstrates that specific forms of selenium (e.g., SEL-PLEX), when administered to a subject, possess the ability to alter (e.g., reduce) gene expression in various tissues (e.g., compared to expression in subjects not administered selenium). | 01-13-2011 |
20110038889 | METHODS AND COMPOSITIONS FOR ALTERING CELL FUNCTION - The present invention relates to compositions and methods for altering cell function. In particular, the present invention provides compositions comprising selenium (e.g., SEL-PLEX) and methods of using the same (e.g., as a therapeutic and/or prophylactic treatment for neurodegenerative disease). Additionally, the present invention demonstrates that specific forms of selenium (e.g., SEL-PLEX) possess the ability to alter expression of genes associated with disease and/or aging while other forms of selenium (e.g., selenomethionine) do not. | 02-17-2011 |
20110280948 | COMPOSITIONS AND METHODS FOR SEPARATING, CHARACTERIZING AND ADMINISTERING SOLUBLE SELENOGLYCOPROTEINS - The invention relates to soluble selenium compositions and methods of production, separation and purification thereof. In particular the present invention provides methods of preparing water soluble selenoglycoproteins (e.g., via extracting selenoglycoproteins from selenium enriched yeast), methods of supplementing a selenium deficient composition via admixing water soluble selenoglycoproteins with the selenium deficient composition, compositions comprising the water soluble selenoglycoproteins and methods of administering the same. | 11-17-2011 |
20120164234 | COMPOSITIONS AND METHODS FOR SEPARATING, CHARACTERIZING AND ADMINISTERING SOLUBLE SELENOGLYCOPROTEINS - The invention relates to soluble selenium compositions and methods of production, separation and purification thereof. In particular the present invention provides methods of preparing water soluble selenoglycoproteins (e.g., via extracting selenoglycoproteins from selenium enriched yeast), methods of supplementing a selenium deficient composition via admixing water soluble selenoglycoproteins with the selenium deficient composition, compositions comprising the water soluble selenoglycoproteins and methods of administering the same. | 06-28-2012 |
20140348872 | COMPOSITIONS AND METHODS FOR ESTABLISHING AND/OR MAINTAINING PREGNANCY - The present invention relates to compositions comprising selenium (e.g., organic selenium (e.g., selenized yeast (e.g., SEL-PLEX))) and methods of using the same (e.g., as a therapeutic and/or prophylactic treatment). For example, the present invention provides compositions comprising selenium (e.g., organic selenium (e.g., selenized yeast (e.g., SEL-PLEX))) and methods of using the same for treating and/or preventing one or more conditions (e.g., problems) disorders, and/or diseases related to establishing and/or maintaining a pregnancy. Compositions and methods of the present invention find use in, among other things, research and clinical (e.g., preventative and therapeutic) applications. | 11-27-2014 |
20160045533 | COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF - The present application relates to compositions comprising selenium compounds, such as 5′-Methylselenoadenosine, Se-Adenosyl-L-homocysteine, Gamma-glutamyl-methylseleno-cysteine, a compound of Formula (I), Formula (II), or Formula (III), and combinations thereof, and methods of using the same for modulating glucose metabolism in a subject. | 02-18-2016 |
20160082033 | COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF - The present application relates to compositions comprising selenium compounds, such as 5′-Methylselenoadenosine, a compound of Formula (I), and combinations thereof, and methods of using the same for inhibiting β amyloid aggregation, ApoE4 expression, p38 or Tau protein phosphorylation, or increasing Neprilysin and Insulin Degrading Enzyme expression. | 03-24-2016 |
Patent application number | Description | Published |
20110035406 | User Interface for Presenting Search Results for Multiple Regions of a Visual Query - A visual query such as a photograph, screen shot, scanned image, or video frame is submitted to a visual query search system from a client system. The search system processes the visual query by sending it to a plurality of parallel search systems, each implementing a distinct visual query search process. A plurality of results is received from the parallel search systems. Utilizing the search results, an interactive results document is created and sent to the client system. The interactive results document has at least one visual identifier for a sub-portion of the visual query with a selectable link to at least one search result for that sub-portion. The visual identifier may be a bounding box around the respective sub-portion, or a semi-transparent label over the respective sub-portion. Optionally, the bounding box or label is color coded by type of result. | 02-10-2011 |
20110131235 | Actionable Search Results for Street View Visual Queries - A server system receives a visual query and information about the current location of the querying device. The server system sends the query and location information to a visual query search system and receives one or more search results in accordance with the visual query and the location information. From the one or more search results, the server system identifies an entity in the visual query. The server system further identifies a client-side action corresponding to the identified entity and creates an actionable search result element configured to launch the client-side action. For example, if the identified entity were a restaurant the actionable search result elements could include buttons to initiate a telephone call, to read reviews, to map the address, or to make a reservation. If the actionable search result is selected, the client system launches the client-side action in an application distinct from the visual query client application. | 06-02-2011 |
20110131241 | Actionable Search Results for Visual Queries - A server system receives a visual query and identifies an entity in the visual query. The server system further identifies a client-side action corresponding to the identified entity and creates an actionable search result element configured to launch the client-side action. Examples of actionable search result elements are buttons to initiate a telephone call, to initiate email message, to map an address, to make a restaurant reservation, and to provide an option to purchase a product. The entity identified in the visual query may be indirectly associated with a client-side action whose contact address or appropriate link is found in a search result associated with the identified entity. The client system receives and displays the actionable search result element, and upon a user selection of the actionable search result element, launches the client-side action in an application distinct from the visual query client application. | 06-02-2011 |
Patent application number | Description | Published |
20150237155 | PROXY SERVER FAILOVER AND LOAD CLUSTERING - Aspects of the present disclosure involve systems, methods, computer program products, and the like, for providing failover and load clustering features to one or more proxy servers of a content delivery network (CDN). In one embodiment, one or more proxy servers may announce a virtual host internet protocol (IP) and, to provide a failover feature, two or more of the proxy servers may also announce a more generic virtual network IP address that includes a broader range of IP addresses associated with the virtual network IP address. In another embodiment, each of the proxy servers in communication with the router may announce a generic IP network address to the router. In response to receiving a request for content from an end user of the CDN, the router may select a proxy server and load balance the received requests among the proxy servers. | 08-20-2015 |
20150237159 | CONTENT DELIVERY NETWORK ARCHITECTURE WITH EDGE PROXY - Aspects of the present disclosure involve systems, methods, computer program products, and the like, for a content delivery network (CDN) architecture utilizing one or more proxy cache devices between a requesting device and an edge cluster of the CDN. The proxy cache device is a relatively high speed device compared to various possible devices making up one or more edge clusters. Thus, if the proxy has cached the requested content, it is capable of directly servicing the client content request at a faster rate than providing the content from the edge cluster. Otherwise, the proxy cache may request the content from an edge cluster and store the content for quick retrieval in response to additional requests for the content. In one embodiment, the proxy cache may perform an analysis of the request or a series of requests to determine if the content is cached at the proxy cache device. | 08-20-2015 |