Pearlman, US
Adam S. Pearlman, Orlando, FL US
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20090305177 | Portable, self-contained fire and water decorative display - A portable, self-contained fire and water apparatus for decorative display. A fireplace for outdoor use in aquatic locations such as a pool, pond or lake. A device that produces a gas flame that burns on the waters surface. The device can be further be enhanced with optional ornamental or informational attachments such as a dragon igniting flaming waters or a sports team helmet floating in a pool surrounded by flames. A method of displaying a decorative or informational display employing a gas flame that burns on a waters surface. | 12-10-2009 |
Adam Sidney Pearlman, Orlando, FL US
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20150084590 | MULTI-CELLULAR CHARGING STATION FOR ELECTRONIC DEVICES AND METHOD OF USE - A new and useful multi-cellular charging station for electronic devices which provides public access to electrical power for the purpose of charging electronic devices such as mobile phones, is secure, accepts payment, and is configurable. Typical situations and settings that would benefit from the availability of such an invention would be tourist areas, bars, lounges, lobbies and other spaces frequented by the public. The apparatus essentially comprises a plurality of locking cells, with a charging means in each. Said cells can be adjoined in a variety of configurations. The invention can further comprise an enclosure and centralized payment means. | 03-26-2015 |
Alexander Pearlman, New York, NY US
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20140221229 | GENOMIC SIGNATURES OF METASTASIS IN PROSTATE CANCER - A method of determining the risk of metastasis of prostate cancer in a human subject who has or had prostate cancer is disclosed herein. The method is based on detecting in a prostate sample from the subject the number of copies per cell of genes and/or genomic regions of a metastatic gene signature set disclosed herein, and determining alternations in the number of copies per cell of the genes and/or genomic regions in the signature set, as compared to the number of copies per cell in non-cancer cells, thereby determining the risk of prostate cancer metastasis. | 08-07-2014 |
Bruce Allen Pearlman, Westfield, NJ US
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20090247743 | PREPARATION OF BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN - Disclosed are materials and methods for preparing optically active β-amino acids of Formula 1, | 10-01-2009 |
20090299093 | Preparation of Gamma-Amino Acids Having Affinity for The Alpha-2-Delta Protein - Disclosed are materials and methods for preparing optically active γ-amino acids of Formula 1, | 12-03-2009 |
Craig Pearlman, Chalfont, PA US
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20150382052 | SYSTEMS AND METHODS FOR GENERATING FOR DISPLAY AN INTERACTIVE MEDIA GUIDE BASED ON USER HISTORY - Systems and methods for efficiently loading interactive media guide data based on user history are provided. A plurality of asset descriptions associated with a first media asset is received. A second media asset related to the first media asset is identified. An asset description is selected form the plurality of asset descriptions based on user history of accessing the second media asset. Data for the first media asset is loaded. Data for the first media asset comprises the selected asset description. | 12-31-2015 |
20150382069 | SYSTEMS AND METHODS FOR LOADING INTERACTIVE MEDIA GUIDE DATA BASED ON USER HISTORY - Systems and methods for efficiently loading interactive media guide data based on user history are provided. A plurality of asset descriptions associated with a first media asset is received. A second media asset related to the first media asset is identified. An asset description is selected form the plurality of asset descriptions based on user history of accessing the second media asset. Data for the first media asset is loaded. Data for the first media asset comprises the selected asset description. | 12-31-2015 |
Dale L. Pearlman, Menlo Park, CA US
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20130123221 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF SKIN DISEASES - Provided herein are compositions, methods and devices for the treatment of skin diseases and disorders in an individual. Described herein are pharmaceutical compositions comprising a non-homogenous vehicle, an alcohol selected from ethanol, isopropanol or n-propanol, at least one excipient, and, optionally, at least one pharmaceutical agent. Additionally, methods are described for the use of said pharmaceutical compositions for the treatment of skin diseases and disorders, and devices are described for the preparation of said pharmaceutical compositions. | 05-16-2013 |
20130243825 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF SKIN DISEASES - Provided herein are chemical matrices, compositions, and methods for the treatment of skin diseases and disorders in an individual. Said chemical matrices and compositions comprise an alcohol selected from ethanol, isopropanol or n-propanol, at least one excipient, and, a corticosteroid, wherein the alcohol is distributed within the chemical matrix as a microbubble and the corticosteroid is present in less than the standardized topical corticosteroid concentration. Additionally, methods are described for the use of said chemical matrices and compositions for the treatment of skin diseases and disorders. | 09-19-2013 |
20130244987 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF SKIN DISEASES - Provided herein are chemical matrices, compositions, methods and devices for the treatment of skin diseases and disorders in an individual. Described herein are non-homogenous chemical matrices and compositions comprising an alcohol selected from ethanol, isopropanol or n-propanol, at least one excipient, and, optionally, at least one pharmaceutical agent, wherein the alcohol is distributed within the chemical matrix as a microbubble. Additionally, methods are described for the use of said chemical matrices and compositions for the treatment of skin diseases and disorders. | 09-19-2013 |
20140024629 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF SKIN DISEASES - Provided herein are chemical matrices, compositions, methods and devices for the treatment of skin diseases and disorders in an individual. Described herein are non-homogenous chemical matrices and compositions comprising an alcohol selected from ethanol, isopropanol or n-propanol, at least one excipient, and, optionally, at least one pharmaceutical agent, wherein the alcohol is distributed within the chemical matrix as a microbubble. Additionally, methods are described for the use of said chemical matrices and compositions for the treatment of skin diseases and disorders. | 01-23-2014 |
20140179649 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF SKIN DISEASES - Provided herein are chemical matrices, compositions, and methods for the treatment of skin diseases and disorders in an individual. Said chemical matrices and compositions comprise an alcohol selected from ethanol, isopropanol or n-propanol, at least one excipient, and, a corticosteroid, wherein the alcohol is distributed within the chemical matrix as a microbubble and the corticosteroid is present in less than the standardized topical corticosteroid concentration. Additionally, methods are described for the use of said chemical matrices and compositions for the treatment of skin diseases and disorders. | 06-26-2014 |
Edward S. Pearlman, South Portland, ME US
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20090095142 | Fingering guide for string instrument (Finger Finder) - An instructional and reference device, for use by violinists, violists, and cellists, is constructed using an outer sleeve or pocket with a sliding panel. The outer sleeve has a larger and a smaller opening, each positioned to reveal information imprinted on the sliding panel. The information revealed through the smaller opening may include musical keys and key signatures. The outer sleeve is imprinted with the names of the strings above the larger opening, through which is revealed the appropriate fingering used on each string when playing in the musical key displayed in the smaller opening of the outer sleeve. Several different inner panels can be used in this musical slide rule, making available fingering information relevant to violin, viola, cello, and/or variants thereof, for different hand positions on these instruments; different inner panels can be used to display fingering information for various positions on the fingerboards of these instruments. Fingering for classical scales of major and minor keys for various modes, and ethnic and stylistic scale patterns, such as are used in jazz, blues, and musical styles native to subcultures around the world may be provided. The inner panel displays the numbers of the appropriate fingers on each string, their relative spacing on each string in each selected musical key, and through various colors or other means may indicate the locations of the root notes of each major and minor key, and arpeggio notes. | 04-16-2009 |
Eric Pearlman, Lakeline, OH US
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20110105426 | COMPOSITIONS AND METHODS FOR TREATING CORNEAL INFLAMMATION - A method of treating corneal inflammation in a subject includes administering to the subject a therapeutically effective amount of a TLR4 antagonist. | 05-05-2011 |
20150306073 | THIOREDOXIN PROTEIN INHIBITORS AND USES THEREOF - A method of treating a fungal infection in a subject including administering to the subject a therapeutically effective amount of a thioredoxin protein inhibitor to treat the fungal infection in the subject. | 10-29-2015 |
Eric Pearlman, Cleveland, OH US
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20150366948 | FUNGAL IRON ACQUISITION INHIBITORS AND USES THEREOF - A method of treating a fungal infection in a subject includes topically administering to the subject a therapeutically effective amount of a fungal iron acquisition inhibitor to treat fungal infection in the subject. | 12-24-2015 |
Howard Pearlman, Haddon Township, NJ US
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20150191352 | FUEL REFORMING SYSTEM AND PROCESS - Fuel reforming processes and systems are disclosed. The fuel reforming process includes providing a fuel reformer, the fuel reformer comprising a reaction zone configured for exothermic partial oxidation to generate reformates and a heat exchanger extending from the reaction zone, the heat exchanger configured to expel the reformates through a reformate path and receive fuel-rich reactants through a fuel path, generating the reformates by the exothermic partial oxidation of the fuel-rich reactants within the reaction zone, heating the fuel-rich reactants in reaction zone with the heat exchanger by heat from the reformates in the reformate path. The process is energetically self-sustained and operates without a catalyst. The fuel reforming system includes the fuel reformer with a spiral heat exchanger and a component capable of operation with the reformates and incompatible with combustion products, such as a fuel cell. | 07-09-2015 |
Jason Ellis Pearlman, Lloyd Harbor, NY US
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20140274375 | SYSTEMS AND METHODS OF FOLLOWING GAME-RELATED CONTENT BASED ON KEYWORDS - A system, machine-readable storage medium storing at least one program, and a computer-implemented method for following game-related content based on keywords is provided. A game server receives a web feed request for a web feed to be displayed on a client device, where the web feed request includes a keyword identifying a type of content to be displayed in the web feed. The game server identifies web feed content to be displayed in the web feed, including identifying content relevant to the keyword. The web feed content may include game content associated with one or more computer-implemented games. The client device is provided with the web feed content to be displayed in the web feed. | 09-18-2014 |
20140274376 | SYSTEMS AND METHODS OF PROVIDING PARENTAL CONTROLS FOR GAME CONTENT - A system, machine-readable storage medium storing at least one program, and a computer-implemented method of providing parental controls for game content is provided. A game server receives a request to access game content associated with a computer-implemented game, including receiving the game request from a game user interface on a client device. In response to the game request, the game server identifies that a safe mode is enabled, where the safe mode prevents restricted game content from being displayed on the game user interface. Safe mode game content in accordance with the safe mode is accessed and provided to the game user interface on the client device, where the safe mode game content includes the requested game content without the restricted game content. | 09-18-2014 |
John Pearlman, Berlin, MA US
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20120167482 | ABRASIVE ARTICLE AND METHOD OF FORMING - An abrasive article having a substrate, a tacking film overlying the substrate, abrasive particles comprising a coating layer bonded to the tacking film such that a bond between the coating layer and the tacking film defines a metallic bonding region, and a bonding layer overlying the abrasive particles and the tacking film, | 07-05-2012 |
20130061535 | ABRASIVE ARTICLE AND METHOD OF FORMING - An abrasive article having a substrate, a tacking film overlying the substrate, abrasive particles comprising a coating layer bonded to the tacking film such that a bond between the coating layer and the tacking film defines a metallic bonding region, and a bonding layer overlying the abrasive particles and the tacking film, | 03-14-2013 |
20130205676 | ABRASIVE ARTICLE AND METHOD OF FORMING - An abrasive article including a substrate made of a wire, abrasive particles affixed to the substrate, the abrasive particles having a first coating layer overlying the abrasive particles, and a second coating layer different than the first coating layer overlying the first coating layer. The abrasive article further including a bonding layer overlying the substrate and abrasive particles. | 08-15-2013 |
20140007513 | ABRASIVE ARTICLE AND METHOD OF FORMING - An abrasive article includes a substrate comprising an elongated body, a tacking layer comprising tin overlying the substrate, and a first type of abrasive particle comprising an agglomerated particle overlying the tacking layer. | 01-09-2014 |
20140017985 | ABRASIVE ARTICLE AND METHOD OF FORMING - An abrasive article includes a substrate, a tacking layer overlying the substrate, a first type of abrasive particle overlying the tacking layer, at least about 5% and not greater than about 99% of a total amount of the first type of abrasive particle has an exposed surface, and a bonding layer overlying at least a portion of the abrasive particles and the tacking layer. | 01-16-2014 |
20140323020 | GRINDING AND POLISHING TOOL - A grinding tool includes a shank having an axis, and at least two abrasive portions mounted directly to and in contact with the shank without a hub therebetween. Each of the abrasive portions has a substantially identical profile formed therein. | 10-30-2014 |
Jonathan Pearlman, Pittsburgh, PA US
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20110245747 | Splint for treatment of musculoskeletal injury of the hand - A splint for treatment of a joint including a generally longitudinal body including first and second portions forming inner and outer splint layers, with the second portion being rollable onto the first portion to form the splint. The outer splint layer may include a longitudinal cavity for insertion of a stay, and/or may include a fluted section for permitting insertion of a stay between the inner and outer splint layers. The longitudinal body may be linear or curved. The first and second portions may include areas having different thicknesses for adding rigidity to the splint structure at a predetermined location. The splint may include a cutout for exposing a predetermined portion of a user's finger. The splint may be made of a flexible material such as rubber, silicone and/or urethane. The splint may include a reduced friction surface layer for minimizing sticking of the splint during donning. | 10-06-2011 |
Jonathan L. Pearlman, Pittsburgh, PA US
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20080319359 | PORTABLE COMPRESSION DEVICE - A portable compression device for compressing at least a portion of a mammal's limb is provided. The portable compression device can use mechanical compression to apply an external pressure to the portion of the limb to thereby propagate blood flow return in the direction of the mammal's heart. In at least one embodiment, the portable compression device can accomplish this mechanical compression through the use of at least one frame, actuator, drum, and flexible elongate member. The actuator can move the drum between a first position and a second position. The flexible elongate member can be engaged with at least a portion of the drum and can at least partially circumscribe a portion of the limb of the mammal, such that the movement of the drum between the first and second positions can apply tension to the flexible elongate member to thereby apply a compressive force to the limb. | 12-25-2008 |
20110162905 | STEERING MECHANISM FOR A PERSONAL VEHICLE - Steering mechanism that increases adjustability. The steering mechanism can have different gear ratios between the input rotation from the user and the output rotation on the drive wheel. The steering device will allow users to employ a pushing or pulling motion for steering instead of pushing to turn in one direction and pulling to turn in the opposite direction. Users with weaker torso strength may not be able to maintain their balance when they pull on a steering tiller. Allowing users to choose the type of motion for steering, and to supplement one motion with the other, creating flexibility and support for users with various abilities. Lastly, the steering system should not impede a user transferring into and out of the personal vehicle. | 07-07-2011 |
20130197732 | ACTIVE STABILITY DEVICES AND SYSTEMS FOR MOBILE DEVICES - A system for use with a mobile device includes at least one sensor to sense a variable related to tilting of the mobile device and at least one activatable system in operative connection with the sensor. The at least one activatable system increases stability of the mobile device upon actuation/change in state thereof on the basis of data measured by the at least one sensor. A variable related to tilting includes variables that indicate concurrent, actual tilting as described herein as well as variables predictive of imminent tilting. Activatable systems hereof change state upon actuation or activation to increase stability of the mobile device by reducing, eliminating or preventing tilting. | 08-01-2013 |
20150198440 | PATHWAY MEASUREMENT DEVICES, SYSTEMS AND METHODS - A pathway measurement system hereof includes a rigid frame and a mobility system attached to the frame. The mobility system includes at least one movable element which is adapted to contact a surface of a pathway via which the frame may be moved relative to the pathway. The pathway measurement system further includes at least one sensor adapted to measure at least one characteristic of a pathway. The pathway measurement system has a first mode of operation in which the mobility system moves the frame along the pathway to move the at least one sensor relative to the pathway. The at least one sensor is connected to the pathway system such that a distance between the at least one sensor and an axis of rotation of one of the moveable elements remains constant in the first mode of operation. In general, the at least one sensor is isolated from any compliance or suspension system. | 07-16-2015 |
20150209207 | SEATING FUNCTION MONITORING AND COACHING SYSTEM - A wheelchair system includes a wheelchair including at least one adjustable seating function, a sensor system in operative connection with the wheelchair which includes at least one sensor to measure or sense a position of the at least one adjustable seating function, a processor system in operative connection with the sensor system, a memory system in operative connection with the processor system, and a communication system in operative connection with the processor system. The communication system is, for example, adapted to wirelessly communicate with one or more remote systems (that is, a system remote from the wheelchair; for example a remote system or server, which may include a database). The wheelchair system further includes a user interface system in operative connection with the processor system and at least one application stored on the memory system and executable by the processor system. The at least one application is executable to provide information via the user interface system to a user of the wheelchair related to data from the sensor system to assist the user to adjust the position of at least one adjustable seating in accordance with parameters stored in the memory system. | 07-30-2015 |
Jonathan Lee Pearlman, Pittsburgh, PA US
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20100276975 | ANGLE ADJUSTABLE BACKREST MOUNTING - Angle adjustable backrest made of a lightweight, durable, adjustable, backrest for ultralight manual wheelchairs. Light-weight material can include composites for a rigid backrest for promotion of healthier and functional interface. Angle adjustment can be any desired range such as a range from −5 degree to 55 degrees (i.e. 85 degrees to 145 degree with respect to horizontal with the seat). No tools are necessary for any of the angle adjustments. The backrest has a horizontal adjustment (fore-aft) that can be any desired range such as 1 inch. The height selection depends on the length of the wheelchair frame tubes. The present invention improves the ease and simplicity of adjusting the backrest by or for the user, as well as enhances the aesthetic appearance and adds features necessary for achieving commercial readiness. The present invention can be retro fit onto a wide range for ultralight wheelchairs. | 11-04-2010 |
20110162166 | MOBILE CASTER - Caster alignment mechanism having a first component operably connected to a leg of a mobile device and a second component operably connected to a caster of the mobile device. The first and second components are positioned in parallel orientation to each other wherein alignment. of the caster with the leg of the mobile device is achieved by the attractive characteristics of the first component with an upper magnet to the second component with a lower magnet. One embodiment of the caster alignment mechanism includes a fixed gap between the upper magnet and the lower magnet for an always engaged or “on” mode. The fixed gap can be adjusted to vary magnetic field strength depending on user specifications for ease of turning. Another embodiment of the caster alignment mechanism includes a switching mechanism to change modes between engaged or “on” mode and disengaged or “off” mode. | 07-07-2011 |
Justin D. Pearlman, Hanover, NH US
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20090264782 | METHOD OF AND SYSTEM FOR SIGNAL SEPARATION DURING MULTIVARIATE PHYSIOLOGICAL MONITORING - Multiple electrode contacts make electrical connections to the anterior and/or posterior chest for multivariate characterization of the electrical activation of the heart. A central processing unit derives synthetic composite electrographic signals as well as flag signals for specific purposes. A preferred embodiment uses this system to trigger or gate magnetic resonance imaging, eliminating or reducing problems from small or inverted R-waves, lead detachment, noise, flow signal, gradient changes, and rhythm changes, more reliably flagging the onset of electrical activation of the ventricles. Additional derived data are ST-segment shifts, filling times, and respiratory cycle. Filling times may be used for greatly improved imaging in the presence of rhythm disturbances, such as atrial fibrillation. Respiratory cycle may be used as a respiratory trigger to control for the effects of breathing on the heart position and image quality. | 10-22-2009 |
20100056938 | METHOD AND SYSTEM FOR SIGNAL SEPARATION DURING MULTIVARIATE PHYSIOLOGICAL MONITORING - Multiple electrode contacts make electrical connections to the anterior and/or posterior chest for multivariate characterization of the electrical activation of the heart. A central processing unit derives synthetic composite electrographic signals as well as flag signals for specific purposes. A preferred embodiment uses this system to trigger or gate magnetic resonance imaging, eliminating or reducing problems from small or inverted R-waves, lead detachment, noise, flow signal, gradient changes, and rhythm changes, more reliably flagging the onset of electrical activation of the ventricles. Additional derived data are ST-segment shifts, filling times, and respiratory cycle. Filling times may be used for greatly improved imaging in the presence of rhythm disturbances, such as atrial fibrillation. Respiratory cycle may be used as a respiratory trigger to control for the effects of breathing on the heart position and image quality. | 03-04-2010 |
Laura Pearlman, Pasadena, CA US
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20110060607 | HEALTH CARE INFORMATION SYSTEMS - A health care information provider system may provide information about health care objects managed by a health care provider. A name generating system may generate an object name for each of the health care objects which may include provider information indicative of the identity of the health care provider which manages the health care object, and object information indicative of the identity of the health care object. The object information may be devoid of any personal health information, even in a form which can be decrypted by a decryption key. | 03-10-2011 |
Lawrence Ahlfert Pearlman, Black Hawk, CO US
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20150272094 | "Smart" Semi-Autonomous Trawler Fishing Net - A system for reducing trawl bycatch through the use of a “flying”, “steerable” element of a towable or trawlerable fishing net, consisting of one or more hydrofoils at the mouth of the net, which maintains either a consistent height over the seabed or a pre-determined depth in the water, semi-autonomously. This negates the need, per the prior art in trawling and fishing technology, for heavy rollers on the bottom of the net, or heavy side “doors”. The present-day use of prior art ruins the ecosystem directly through physical damage to coral, sea bed hatcheries, etc., and indirectly by requiring increased fuel use on the trawling vessel and thus creating more emissions. This invention addresses those problems providing a better, cleaner and less destructive technology for fishing. | 10-01-2015 |
Leah Pearlman, San Francisco, CA US
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20150082462 | Selective Content Accessibility in a Social Network - A social networking service encourages users to post content to a communication channel with varying levels of accessibility to other users. Users may select how content will be published and control the accessibility of uploaded content using a privacy setting for each content item that the user posts. The privacy setting defines, or identifies, the set of connections who may view the posted content item. The posted content item is placed in a particular communication channel in the social networking service, such as a newsfeed or stream, where the content item can be viewed by those who are permitted to view it according to its associated privacy setting. Varying granularities of privacy settings provide flexibility for content accessibility on a social networking service. | 03-19-2015 |
Leah Pearlman, Denver, CO US
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20100318571 | Selective Content Accessibility in a Social Network - A social networking service encourages users to post content to a communication channel with varying levels of accessibility to other users. Users may select how content will be published and control the accessibility of uploaded content using a privacy setting for each content item that the user posts. The privacy setting defines, or identifies, the set of connections who may view the posted content item. The posted content item is placed in a particular communication channel in the social networking service, such as a newsfeed or stream, where the content item can be viewed by those who are permitted to view it according to its associated privacy setting. Varying granularities of privacy settings provide flexibility for content accessibility on a social networking service. | 12-16-2010 |
20130019319 | Selective Content Accessibility in a Social Network - A social networking service encourages users to post content to a communication channel with varying levels of accessibility to other users. Users may select how content will be published and control the accessibility of uploaded content using a privacy setting for each content item that the user posts. The privacy setting defines, or identifies, the set of connections who may view the posted content item. The posted content item is placed in a particular communication channel in the social networking service, such as a newsfeed or stream, where the content item can be viewed by those who are permitted to view it according to its associated privacy setting. Varying granularities of privacy settings provide flexibility for content accessibility on a social networking service. | 01-17-2013 |
Marc Pearlman, Niskayuna, NY US
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20150382231 | DYNAMIC ADJUSTMENT OF A WIRELESS NETWORK MEDIA ACCESS CONTROL PARAMETER - According to some embodiments, information associated with collisions occurring as packets are exchanged through a wireless network may be measured. At least one media access control parameter may then be automatically and dynamically adjusted to achieve a throughput requirement, at a relatively low latency, while reducing collisions in the wireless network. | 12-31-2015 |
Paul S. Pearlman, Thornton, PA US
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20090182163 | PROCESS FOR MAKING AND REFINING 3-PENTENENITRILE, AND FOR REFINING 2-METHYL-3-BUTENENITRILE - The invention provides an integrated, continuous process for the production of 3-pentenenitrile, the refining of 3-pentenenitrile, and the refining of 2-methyl-3-butenenitrile, the process comprising: | 07-16-2009 |
20090182164 | HYDROCYANATION OF PENTENENITRILES - The invention provides a hydrocyanation process to produce adiponitrile and other dinitriles having six carbon atoms, in the presence of catalyst composition comprising a zero-valent nickel and at least one bidentate phosphorus-containing ligand wherein the bidentate phosphorus-containing ligand gives acceptable results according to at least one protocol of the 2-Pentenenitrile Hydrocyanation Test Method. | 07-16-2009 |
20130053583 | DEPOLYMERIZATION OF OLIGOMERIC CYCLIC ETHERS - The present invention provides a method for depolymerization of a mixture comprising oligomeric cyclic ethers resulting from copolymerization of at least one tetrahydrofuran and at least one other cyclic ether to recover tetrahydrofuran monomer. | 02-28-2013 |
20130189753 | METHODS FOR BIOSYNTHESIZING 1,3 BUTADIENE - This document describes biochemical pathways for producing butadiene by forming two vinyl groups in a butadiene synthesis substrate. These pathways described herein rely on enzymes such as mevalonate diphosphate decarboxylase, isoprene synthase, and dehydratases for the final enzymatic step. | 07-25-2013 |
20130210090 | METHODS OF MAKING NYLON INTERMEDIATES FROM GLYCEROL - Embodiments of the invention relate to the enzymatic conversion of bioderived feedstocks to commercially valuable chemicals. The enzymatic conversions of the embodiments of the invention offer the potential for lower cost routes to these value-added chemicals. Some of the chemicals that are useful include nylon intermediates such as caprolactam, adipic acid, 1,6-hexamethylene diamine; butanediols such as 1,4-butanediol, 1,3-butanediol, and 2,3-butanediol; butanols such as 1-butanol, and 2-butanol; succinic acid, butadiene, isoprene, and 3-hydroxypropanoic acid. | 08-15-2013 |
20130210104 | METHODS OF PRODUCING FOUR CARBON MOLECULES - Disclosed are methods for producing butadiene from one or more of several diverse feedstocks including bioderived feedstocks, renewable feedstocks, petrochemical feedstocks and natural gas. | 08-15-2013 |
20130217081 | BIOCATALYTIC METHODS TO CONVERT CYCLOHEXANE OXIDATION PROCESS WASTE STREAMS TO USEFUL PRODUCTS - The invention relates to methods for enriching monomer content in a cycloalkane oxidation process mixed organic waste stream. In particular, the methods involve combining a biocatalyst with a mixed organic waste stream from a cycloalkane oxidation process, and enzymatically converting dimeric and/or oligomeric components of said waste stream into monomeric components. The methods may enrich the content of diacids, adipic acid, and/or other α,ω-difunctional C6 alkanes in the mixed organic waste stream. Additionally, the treated mixed organic waste streams may have improved burning efficiency. | 08-22-2013 |
20130224807 | METHODS OF PRODUCING CARBOXYLIC ACIDS - The invention relates to methods for enriching monomer content in a cycloalkane oxidation process mixed organic waste stream. In particular, the methods involve combining a biocatalyst with a mixed organic waste stream from a cycloalkane oxidation process, and enzymatically converting dimeric and/or oligomeric components of said waste stream into monomeric components. The methods may enrich the content of diacids, adipic acid, and/or other α,ω-difunctional C6 alkanes in the mixed organic waste stream. Additionally, the treated mixed organic waste streams may have improved burning efficiency. | 08-29-2013 |
20140141482 | METHODS FOR BIOSYNTHESIZING 1,3 BUTADIENE - This document describes biochemical pathways for producing butadiene by forming two vinyl groups in a butadiene synthesis substrate. These pathways described herein rely on enzymes such as mevalonate diphosphate decarboxylase, isoprene synthase, and dehydratases for the final enzymatic step. | 05-22-2014 |
20140186904 | Methods Of Producing 7-Carbon Chemicals Via Methyl-Ester Shielded Carbon Chain Elongation - This document describes biochemical pathways for producing pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a C7 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on enzymes or homologs accepting methyl ester shielded dicarboxylic acid substrates. | 07-03-2014 |
20140193861 | Methods Of Producing 7-Carbon Chemicals Via Aromatic Compounds - This document describes biochemical pathways for producing pimelic acid, 7-aminoheptanoate, 7-hydroxyheptanoate, heptamethylenediamine, or 1,7-heptanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a C7 aliphatic backbone substrate produced from chorismate or benzoate. These pathways, metabolic engineering and cultivation strategies described herein rely on the anaerobic benzoyl-CoA degradation pathway enzymes. | 07-10-2014 |
20140193862 | Methods Of Producing 7-Carbon Chemicals Via Carbon Chain Elongation Associated With Cyclohexane Carboxylate Synthesis - This document describes biochemical pathways for producing pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a C7 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on the carbon chain elongation enzymes or homologs thereof associated with the cyclohexane carboxylate biosynthesis from | 07-10-2014 |
20140193863 | Methods Of Producing 7-Carbon Chemicals Via C1 Carbon Chain Elongation Associated With Coenzyme B Synthesis - This document describes biochemical pathways for producing pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol by forming one or two terminal functional groups, each comprised of carboxyl, amine or hydroxyl group, in a C7 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on the C1 elongation enzymes or homolog associated with coenzyme B biosynthesis. | 07-10-2014 |
20140193864 | Methods Of Producing 7-Carbon Chemicals Via Pyruvate And Succinate Semialdehyde Aldol Condensation - This document describes biochemical pathways for producing one or more of pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine and 1,7-heptanediol by forming one or two terminal functional groups, comprised of carboxyl, amine or hydroxyl groups, in a C7 aliphatic backbone substrate produced from succinate semialdehyde or pyruvate. These pathways, metabolic engineering and cultivation strategies described herein rely on the aldol condensation of succinate semialdehyde and pyruvate. | 07-10-2014 |
20140193865 | Methods Of Producing 7-Carbon Chemicals From Long Chain Fatty Acids Via Oxidative Cleavage - This document describes biochemical pathways for producing pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a C7 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on the fatty acid synthesis pathway and oxidative cleavage of long chain acyl-[acp] intermediates by a monooxgenase (e.g., cytochrome P450) such as that encoded by BioI from microorganisms such as | 07-10-2014 |
20140242655 | Bioconversion Process for Producing Nylon-7, Nylon-7, 7 and Polyesters - Embodiments of the present invention relate to methods for the biosynthesis of di- or trifunctional C7 alkanes in the presence of isolated enzymes or in the presence of a recombinant host cell expressing those enzymes. The di- or trifunctional C7 alkanes are useful as intermediates in the production of nylon-7, nylon-7,x, nylon-x,7, and polyesters. | 08-28-2014 |
20150337275 | BIOCONVERSION PROCESS FOR PRODUCING NYLON-7, NYLON-7,7 AND POLYESTERS - Embodiments of the present invention relate to methods for the biosynthesis of di- or trifunctional C7 alkanes in the presence of isolated enzymes or in the presence of a recombinant host cell expressing those enzymes. The di- or trifunctional C7 alkanes are useful as intermediates in the production of nylon-7, nylon-7,x, nylon-x,7, and polyesters. | 11-26-2015 |
Philip A. Pearlman, Broomall, PA US
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20130334153 | ORGANIZATIONAL STRUCTURE FOR SUPPORTING AN OBJECT IN A VERTICAL MANNER - An organizational structure for supporting an object in at least a generally vertical manner includes a generally planar first support surface having a first end and an opposing second end. The first support surface extends in a first plane. A generally planar second support surface has a first end and an opposing second end. The second support surface extends in a second plane. The second plane extends generally perpendicularly to the first plane. A plurality of laterally spaced-apart strands extends parallel to one another. A first end of each strand is secured to the first support surface at a location spaced-apart from the first and second ends thereof. An opposing second end of each strand is secured to the second support surface at a location spaced-apart from the first and second ends thereof. | 12-19-2013 |
Richard Pearlman, Carlsbad, CA US
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20100030466 | System and Method for Hybrid Off-Board Navigation - A system, method and apparatus for hybrid off-board vehicle navigation are disclosed. In the system, a multi-stop route package is created and sent from a route server to a navigation device. The route package can include a collection of vehicle attributes and corresponding road restrictions for guiding the vehicle towards its destination. The server can optionally push the route package to the vehicle in an email message or other stored communication. When an off-route condition is detected, the navigation device can send a route request to the server that includes the vehicle attributes and the corresponding road restrictions. The server can respond with a partial route correction that is determined based on the vehicle attributes and road restrictions. | 02-04-2010 |
20130185193 | FRAUD MINIMIZATION AND ANALYTICS THROUGH GEOSPATIAL COMPARISON OF VEHICLE LOCATION AND TRANSACTION SITUS - A method comprising determining that a transaction associated with a purchase of a fuel of a vehicle equipped with a geospatial positioning device is associated with a unique identifier of a fuel card is disclosed. The method may comprise comparing a present geospatial location of the vehicle with a situs where the transaction associated with the purchase of the fuel of the vehicle is determined when a distance between the vehicle and the situs where the transaction associated with the purchase of the fuel of the vehicle occurs is within a threshold limit. The method may also comprise generating an alert communication to a party based on a transgression of the vehicle from the threshold limit. | 07-18-2013 |
20150112584 | SYSTEM AND METHOD FOR HYBRID OFF-BOARD NAVIGATION - A system, method and apparatus for hybrid off-board vehicle navigation are disclosed. In the system, a multi-stop route package is created and sent from a route server to a navigation device. The route package can include a collection of vehicle attributes and corresponding road restrictions for guiding the vehicle towards its destination. The server can optionally push the route package to the vehicle in an email message or other stored communication. When an off-route condition is detected, the navigation device can send a route request to the server that includes the vehicle attributes and the corresponding road restrictions. The server can respond with a partial route correction that is determined based on the vehicle attributes and road restrictions. | 04-23-2015 |
Richard Frank Pearlman, Carlsbad, CA US
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20130141249 | GEOSPATIAL DATA BASED ASSESSMENT OF DRIVER BEHAVIOR - A method of geospatial data based assessment driver behavior to improve driver safety and efficiency is disclosed. A method of a server device may comprise determining that a telemetry data is associated with a vehicle communicatively coupled with the server device and comparing the telemetry data with a driver objective data. A variance between the telemetry data and the driver objective data may then be determined. A performance score may be generated upon comparison of the variance to a threshold limit and/or the driver objective data. The performance score may be published along with other performance scores of other drivers in other vehicles also communicatively coupled with the server device to a reporting dashboard module. Elements of game theory may be implemented to create a team driving challenge and/or a driver performance program to generate the performance score to improve driver safety and efficiency for commercial fleets. | 06-06-2013 |
20130302757 | GEOSPATIAL DATA BASED ASSESSMENT OF DRIVER BEHAVIOR - A method of geospatial data based assessment driver behavior to improve driver safety and efficiency is disclosed. A method of a server device may comprise determining that a telemetry data is associated with a vehicle communicatively coupled with the server device and comparing the telemetry data with a driver objective data. A variance between the telemetry data and the driver objective data may then be determined. A performance score may be generated upon comparison of the variance to a threshold limit and/or the driver objective data. The performance score may be published along with other performance scores of other drivers in other vehicles also communicatively coupled with the server device to a reporting dashboard module. Elements of game theory may be implemented to create a team driving challenge and/or a driver performance program to generate the performance score to improve driver safety and efficiency for commercial fleets. | 11-14-2013 |
20140012634 | GEOSPATIAL DATA BASED ASSESSMENT OF FLEET DRIVER BEHAVIOR - Disclosed are methods, devices, and systems to assess the performance of a fleet driver using a geospatial tracking device. In one embodiment, a method is disclosed comprising determining a baseline travel time of a fleet vehicle traveling a fleet route from a departure location to an arrival location; obtaining a dispatch estimated travel time of the fleet vehicle traveling the fleet route from a dispatcher; obtaining a driver estimated travel time of the fleet vehicle; determining an actual travel time of the fleet vehicle traveling the fleet route through a geospatial tracking device; and generating a driver performance score of the driver of the fleet vehicle for a duration of the fleet route based on the baseline travel time, the dispatch estimated travel time, the driver estimated travel time, and/or the actual travel time. | 01-09-2014 |
20150019270 | OPERATOR BENEFITS AND REWARDS THROUGH SENSORY TRACKING OF A VEHICLE - Disclosed are a method, a device and/or a system of an operator benefits and rewards through sensory tracking of a vehicle. In one aspect, a method includes associating a private vehicle with an individual. A behavior of the individual is monitored when the individual is operating the private vehicle. The method includes determining whether the individual is adhering to a set of parameters set by an entity. Information is presented to the individual that they have earned a credit towards a benefit based on operating of the private vehicle. The entity may be permitted to configure the set of parameters and set a weight to each of the set of parameters. A punitive measure may be provided when the set of parameters is violated. A curfew range may be set on the private vehicle such that a movement of the private vehicle is limited to the curfew range. | 01-15-2015 |
Rodney Pearlman, El Granada, CA US
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20100158905 | COMBINATION THERAPY OF ARTHRITIS WITH TRANILAST - Combination therapy is disclosed herein for the treatment an arthritic condition (e.g. rheumatoid arthritis, osteoarthritis or psoriatic arthritis). The therapies disclosed herein comprise administering tranilast or an analogous compound in combination with a pharmaceutical agent, such as a non-steroidal anti-inflammatory drug, a disease-modifying drug, a COX-2 inhibitor, an antibiotic, an analgesic or combination thereof. | 06-24-2010 |
20100160351 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING HYPERURICEMIA AND RELATED DISORDERS - Disclosed is a pharmaceutical composition comprising (a) a first therapeutic agent, wherein the first therapeutic agent is a compound of formula II: | 06-24-2010 |
20150174076 | MUCOADHESIVE DEVICES FOR DELIVERY OF ACTIVE AGENTS - Described herein are systems and methods for transmucosal delivery of active agents. In some embodiments, a system may comprise one or more mucoadhesive devices configured for release of an active agent. | 06-25-2015 |