Patent application number | Description | Published |
20080206207 | Intracoronary Device And Method Of Use Thereof - Engraftment of therapeutic cells and agents to a target site in an organism is enhanced by mechanical, chemical and biological methods and systems. | 08-28-2008 |
20080287911 | CATHETER WITH LAMINAR FLOW DRUG DELIVERY PROPERTIES - Catheters with laminar flow bioactive agent delivery properties and methods of using for treating or preventing vascular disease are disclosed. | 11-20-2008 |
20100047315 | Stent for Increasing Blood Flow to Ischemic Tissues and a Method of Using the Same - Stents and a method of using the stents to increase blood flow to ischemic tissues in a patient are disclosed. | 02-25-2010 |
20100144635 | METHODS AND COMPOSITIONS TO TREAT MYOCARDIAL CONDITIONS - Methods, devices, kits and compositions to treat a myocardial infarction. In one embodiment, the method includes the prevention of remodeling of the infarct zone of the ventricle. In other embodiments, the method includes the introduction of structurally reinforcing agents. In other embodiments, agents are introduced into a ventricle to increase compliance of the ventricle. In an alternative embodiment, the prevention of remodeling includes the prevention of thinning of the ventricular infarct zone. In another embodiment, the prevention of remodeling and thinning of the infarct zone involves the cross-linking of collagen and prevention of collagen slipping. In other embodiments, the structurally reinforcing agent may be accompanied by other therapeutic agents. These agents may include but are not limited to pro-fibroblastic and angiogenic agents. | 06-10-2010 |
20100233263 | METHODS AND COMPOSITIONS FOR TREATMENT OF LESIONED SITES OF BODY VESSELS - Methods and compositions for inducing apoptosis of cells, such as macrophages, at a lesioned site of a body vessel are disclosed herein. Nitric oxide can be directly or indirectly delivered to a treatment site to increase macrophage apoptosis. Delivery can include site specific delivery of nitric oxide gas, nitric oxide in aqueous solution or a substance(s) which releases nitric oxide or causes nitric oxide to be generated from an endogenous source. Delivery can be achieved by a delivery system such as a catheter assembly, stent or other suitable device. | 09-16-2010 |
20110270225 | METHOD FOR INCREASED UPTAKE OF BENEFICIAL AGENT AND EJECTION FRACTION BY POSTCONDITIONING PROCEDURES - A method for improving tissue uptake of beneficial agent and ejection fraction. | 11-03-2011 |
20110288478 | BALLOON CATHETER EXHIBITING RAPID INFLATION AND DEFLATION - A catheter capable of rapid inflation and deflation and operation by one individual. | 11-24-2011 |
20110319866 | METHODS AND DEVICE FOR SYNERGISTIC MITIGATION OF REPERFUSION INJURY AFTER AN ISCHEMIC EVENT - A method for synergistic mitigation of reperfusion injury after an ischemia event in a subject. | 12-29-2011 |
20120034222 | Nitric Oxide Generating Medical Devices - Medical devices having a catalyst capable of catalyzing the generation of nitric oxide in vivo and methods of treating a vascular condition using the devices are provided. | 02-09-2012 |
20120064098 | Intracoronary Device And Method Of Use Thereof - Engraftment of therapeutic cells and agents to a target site in an organism is enhanced by mechanical, chemical and biological methods and systems. | 03-15-2012 |
20120148609 | INTRACORONARY DEVICE AND METHOD OF USE THEREOF - Engraftment of therapeutic cells and agents to a target site in an organism is enhanced by mechanical, chemical and biological methods and systems. | 06-14-2012 |
20120148668 | INTRACORONARY DEVICE AND METHOD OF USE THEREOF - Engraftment of therapeutic cells and agents to a target site in an organism is enhanced by mechanical, chemical and biological methods and systems. | 06-14-2012 |
20120157751 | INTRACORONARY DEVICE AND METHOD OF USE THEREOF - Engraftment of therapeutic cells and agents to a target site in an organism is enhanced by mechanical, chemical and biological methods and systems. | 06-21-2012 |
20120219521 | METHODS AND COMPOSITIONS TO TREAT MYOCARDIAL CONDITIONS - Methods, devices, kits and compositions to treat a myocardial infarction. In one embodiment, the method includes the prevention of remodeling of the infarct zone of the ventricle. In other embodiments, the method includes the introduction of structurally reinforcing agents. In other embodiments, agents are introduced into a ventricle to increase compliance of the ventricle. In an alternative embodiment, the prevention of remodeling includes the prevention of thinning of the ventricular infarct zone. In another embodiment, the prevention of remodeling and thinning of the infarct zone involves the cross-linking of collagen and prevention of collagen slipping. In other embodiments, the structurally reinforcing agent may be accompanied by other therapeutic agents. These agents may include but are not limited to pro-fibroblastic and angiogenic agents. | 08-30-2012 |
20130060206 | SPIRAL THROMBECTOMY CATHETER - The subject matter relates a catheter having a helical or spiral tip defining an aspiration port for removing obstructions from blood vessels. | 03-07-2013 |
20130103138 | SURFACE MODIFICATION OF MEDICAL DEVICES TO ENHANCE ENDOTHELIAL ADHESION AND COVERAGE - Acceleration of the endothelialization process on implantable medical devices having at least one blood-contacting surface is achieved by a microscale pattern of sub-sections of EC-inductive coatings or EC-conductive coatings and nano/macro textured surfaces. The EC-inductive coating and EC-conductive coating can be applied either on the entire surface of the blood-contacting surface or selective placed on the blood-contacting surface, for example, in particular patterns. In this regard, the EC-conductive and EC-inductive coatings can be selectively placed relative to the textured surface to achieve a desired pattern of texture surface to coatings. | 04-25-2013 |
20130165858 | APPARATUS TO PREVENT REPURFUSION INJURY - Embodiments of a method and apparatus to prevent reperfusion injury. In one embodiment, blood flow proximal to a lesion is occluded. An infusion catheter is advanced to a region distal to the lesion and an anti-reperfusion injury drug is delivered. The lesion may then be treated with a dilating device to reintroduce blood flow to the region distal to the lesion. | 06-27-2013 |
20130317591 | DRUG ELUTING STENT FOR THE TREATMENT OF DIALYSIS GRAFT STENOSES - A drug-eluting stent having a first cell pattern at one end and a second cell pattern on an opposite end. The cells in the first cell pattern have a smaller MCUSA than those in the second cell pattern. An anti-restonic drug can be coated on the first cell pattern and an anti-thrombotic drug on the second, with the anti-thrombotic drug overlaying and covering both the first and second cell patterns. The stent is operatively positionable at a distal graft-vein anastomosis with the first cell pattern adjacent the stenosis, and with the second cell pattern positioned adjacent the vein or the graft. | 11-28-2013 |
20130344047 | Methods And Composition For Treating Heart Failure And Ischemia - Methods and compositions for treating heart failure by administration of beneficial agents to the heart. | 12-26-2013 |
20140052052 | NEEDLE CATHETER FOR DELIVERY OF AGENTS DIRECTLY INTO VESSEL WALL - A system and method for treating a patient including advancing a catheter into the vasculature of the patient, forcing the catheter to adopt a position in contact with a vessel wall, and causing a needle tip to advance into the wall from a lumen in the catheter external surface that is in contact with the wall. | 02-20-2014 |
20140154300 | METHODS AND COMPOSITIONS FOR TREATMENT OF LESIONED SITES OF BODY VESSELS - Methods and compositions for inducing apoptosis of cells, such as macrophages, at a lesioned site of a body vessel are disclosed herein. Nitric oxide can be directly or indirectly delivered to a treatment site to increase macrophage apoptosis. Delivery can include site specific delivery of nitric oxide gas, nitric oxide in aqueous solution or a substance(s) which releases nitric oxide or causes nitric oxide to be generated from an endogenous source. Delivery can be achieved by a delivery system such as a catheter assembly, stent or other suitable device. | 06-05-2014 |
20140212355 | TRANS-ARTERIAL DRUG DELIVERY - It is provided herein methods, devices, and compositions for trans-arterial local delivery of therapeutic agent for the treatment of liver cancers. | 07-31-2014 |
20150073535 | Treatment of coronary artery lesions with a scaffold having vessel scaffold interactions that reduce or prevent angina - Methods of treating coronary artery disease (CAD) with bioresorbable stents resulting in reduced angina or non-ischemic chest pain are described. Methods of treatment and devices for treatment of angina and post-procedural chest pain that include anti-angina agents incorporated into the device are disclosed. | 03-12-2015 |