Patent application number | Description | Published |
20090246296 | METHOD OF TREATING ISCHEMIA/REPERFUSION INJURY WITH NITROXYL DONORS - Nitroxyl donating compounds are administered prior to the onset of ischemia for the prevention and/or reduction of ischemia/reperfusion injury in subjects at risk for ischemia. Nitroxyl donors also are administered to organs to be transplanted for the prevention and/or reduction of ischemia/reperfusion injury upon reperfusion in a recipient. Nitroxyl donors include any nitroxyl donating compound. In particular cases the nitroxyl donor is a nitroxyl-donating diazeniumdiolate, such as Angeli's salt or IPA/NO. | 10-01-2009 |
20090280194 | USE OF NITROXYL (HNO) FOR THE TREATMENT OF CANCERS OVEREXPRESSING MAT-8 - Compositions and methods for treating hormone dependent or independent cancers overexpressing MAT-8 in a patient by administration of nitroxyl-donating compounds and treating patient suffering from cancers such as prostate cancer, breast cancer, pancreatic cancer, colon cancer and lung cancer. | 11-12-2009 |
20090286883 | TREATMENT OF HEART FAILURE AND ASSOCIATED CONDITIONS BY ADMINISTRATION OF MONOAMINE OXIDASE INHIBITORS - Administration of monoamine oxidase inhibitors is useful in the prevention and treatment of heart failure and incipient heart failure. | 11-19-2009 |
20090298795 | Thiol-Sensitive Positive Inotropes - The present invention relates to methods for treating diastolic dysfunction or a disease, disorder or condition associated with diastolic dysfunction, methods for treating heart failure, methods for modulating SR Ca2+ release and/or uptake, methods for enhancing myocyte relaxation, preload or E2P hydrolysis, and methods for treating ventricular hypertrophy. | 12-03-2009 |
20110081427 | Nitroxyl Progenitors in the Treatment of Heart Failure - Administration of an HNO/NO | 04-07-2011 |
20120201907 | Nitroxyl Progenitors in the Treatment of Heart Failure - Administration of an HNO/NO | 08-09-2012 |
20120231482 | METHOD, KIT OR DIAGNOSTIC FOR THE DETECTION OF REAGENTS WHICH INDUCE ALTERED CONTRACTILITY - A method of screening for compounds that enhance or depress contractile function, based on measuring the formation of heterodimers of contractile fibers (e.g. Tm and actin, myosin heavy and myosin light chains), for example through disulfide bond formation. Diagnostic and prognostic methods and kits are also provided. | 09-13-2012 |
20150011643 | TREATMENT OF HEART FAILURE AND ASSOCIATED CONDITIONS BY ADMINISTRATION OF MONOAMINE OXIDASE INHIBITORS - Administration of monoamine oxidase inhibitors is useful in the prevention and treatment of heart failure and incipient heart failure. | 01-08-2015 |