Ongenae
Al W. Ongenae, Lac Du Bonnet CA
Patent application number | Description | Published |
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20110259459 | Turbo saver - The turbosaver is inserted into The exhaust of an engine with A turbo to prevent the turbo From free spinning with no Lubrication while being Transported with the Engine in the off position | 10-27-2011 |
Nicolas Ongenae, Gentbrugge BE
Patent application number | Description | Published |
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20150140011 | IL-6 BINDING MOLECULES - The present invention provides binding molecules (e.g., antibodies or antigen binding fragments thereof) that specifically bind to and inhibit the biological activity of IL-6 (e.g., human, mouse and non-human primate IL-6). In a preferred embodiment, the antibodies or antigen binding fragments of the invention bind to IL-6 and inhibit its binding to an IL-6 receptor. Such antibodies or antigen binding fragments are particularly useful for treating IL-6-associated diseases or disorders (e.g., inflammatory disease and cancer). | 05-21-2015 |
Nicolas G. H. Ongenae, Gent BE
Patent application number | Description | Published |
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20150218239 | FCRN Antagonists and Methods of Use - Provided are novel FcRn antagonist compositions comprising a variant Fc region that binds specifically to FcRn with increased affinity and reduced pH dependence relative to the native Fc region. Also provided are FcRn antagonists with enhanced CD16 binding affinity. Also provided are methods of treating antibody-mediated disorders (e.g. autoimmune diseases) using the these FcRn antagonist compositions, nucleic acids encoding the FcRn antagonist compositions, recombinant expression vectors and host cells for making the FcRn antagonist compositions, and pharmaceutical compositions comprising the FcRn antagonist compositions. | 08-06-2015 |