Nick A.
Nick A. Benkirane, Boca Raton, FL US
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20090231361 | RAPID LOCALIZED LANGUAGE DEVELOPMENT FOR VIDEO MATRIX SWITCHING SYSTEM - Systems and methods are provided for selecting a subset of Unicode characters and overlaying the Unicode characters on graphical images, videos or other media that are displayed on a user interface. The Unicode characters may include both ASCII characters and non-ASCII characters. Tools are provided for dynamically modifying and selecting image patterns, symbols or icons that represent non-ASCII and ASCII character fonts. Applications are provided for editing, verifying and managing the image patterns, symbols or icons that represent character fonts. | 09-17-2009 |
Nick A. Cicone, Rochester Hills, MI US
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20140311109 | PUSH LOCK DIFFERENTIAL PRESSURE SENSOR - A diesel particulate filter is provided and may include a filter housing having an inlet and an outlet and a filter element disposed within the filter housing. A first metal conduit may be in fluid communication with an interior of the filter housing between the inlet and the filter element and a second metal conduit may be in fluid communication with the interior of the filter housing between the filter element and the outlet. A sensor assembly including a sensor housing may have a first port receiving the first metal conduit and a second port receiving the second metal conduit. | 10-23-2014 |
Nick A. Mould, Norman, OK US
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20080263323 | Reconfigurable Computing Architectures: Dynamic and Steering Vector Methods - A reconfigurable processor including a plurality of reconfigurable slots, a memory, an instruction queue, a configuration selection unit, and a configuration loader. The plurality of reconfigurable slots are capable of forming reconfigurable execution units. The memory stores a plurality of steering vector processing hardware configurations for configuring the reconfigurable execution units. The instruction queue stores a plurality of instructions to be executed by at least one of the reconfigurable execution units. The configuration selection unit analyzes the dependency of instructions stored in the instruction queue to determine an error metric value for each of the steering vector processing hardware configurations indicative of an ability of a reconfigurable slot configured with the steering vector processing hardware configuration to execute the instructions in the instruction queue, and chooses one of the steering vector processing hardware configurations based upon the error metric values. The configuration loader determines whether one or more of the reconfigurable slots are available and reconfigures at least one of the reconfigurable slots with at least a part of the chosen steering vector processing hardware configuration responsive to at least one of the reconfigurable slots being available. | 10-23-2008 |
Nick A. Nolcheff, Chandler, AZ US
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20080273982 | BLADE ATTACHMENT RETENTION DEVICE - A component for a gas turbine engine includes a rotor disk, a plurality of blade attachments, a plurality of retention flanges, and a plurality of retention tabs. The rotor disk has a plurality of slots formed in an outer surface thereof. Each blade attachment has an attachment region configured to be partially disposed within one of the slots. The plurality of retention flanges extend from the rotor disk outer surface, to thereby at least inhibit axial movement of the blade attachment, when the attachment region is fitted inside its corresponding slot. A retention tab extends from each attachment region and engages one of the retention flanges. | 11-06-2008 |
20090304502 | PRE-DIFFUSER FOR CENTRIFUGAL COMPRESSOR - A diffuser system for a compressor for a gas turbine engine, the compressor having an impeller and the gas turbine engine having a combustor and a fuel injector proximate to the combustor, includes a first diffuser and a second diffuser. The first diffuser is configured to receive compressed air from the impeller. The second diffuser is coupled to receive the compressed air from the first diffuser. The second diffuser comprises a housing comprising a first wall and a second wall. The first and second walls form a diffuser flow passage therebetween. The first wall or the second wall, or both, further form an opening through the first and second walls for the fuel injector to pass through when removed from the combustor. | 12-10-2009 |
20100111688 | AXIAL-CENTRIFUGAL COMPRESSOR WITH PORTED SHROUD - A compressor includes a housing, a rotor, an impeller, and a ported shroud. The rotor is mounted within the housing, and has a first leading edge and a first trailing edge. The rotor is operable, upon rotation thereof, to compress air and to discharge the air in an approximately axial direction. The impeller is mounted within the housing, and has a second leading edge and a second trailing edge. The impeller is operable, upon rotation thereof, to receive the air discharged from the rotor, to further compress the air, and to discharge the air in an approximately radial direction. The shroud at least partially surrounds the impeller. The shroud has an opening therein to at least facilitate allowing the air to travel upstream of the opening. | 05-06-2010 |
Nick A. Paras, Thousand Oaks, CA US
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20110251199 | NITROGEN-CONTAINING BICYCLIC HETEROARYL COMPOUNDS AND METHODS OF USE - The present invention comprises a new class of compounds capable of modulating Raf kinase and, accordingly, useful for treatment of Raf kinase mediated diseases, including melanomas, tumors and other cancer-related conditions. The compounds have a general Formula I | 10-13-2011 |
Nick A. Paras, San Francisco, CA US
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20120329830 | Amino Heteroaryl Compounds as Beta-Secretase Modulators and Methods of Use - The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula I wherein ring A, B | 12-27-2012 |
20130018064 | Amino Heteroaryl Compounds as Beta-Secretase Modulators and Methods of UseAANM Paras; Nick A.AACI San FranciscoAAST CAAACO USAAGP Paras; Nick A. San Francisco CA USAANM Cheng; YuanAACI Newbury ParkAAST CAAACO USAAGP Cheng; Yuan Newbury Park CA USAANM Powers; TimothyAACI MalibuAAST CAAACO USAAGP Powers; Timothy Malibu CA USAANM Brown; JamesAACI MoorparkAAST CAAACO USAAGP Brown; James Moorpark CA USAANM Hitchcock; Stephen A.AACI JupiterAAST FLAACO USAAGP Hitchcock; Stephen A. Jupiter FL USAANM Judd; TedAACI Simi ValleyAAST CAAACO USAAGP Judd; Ted Simi Valley CA USAANM Lopez; PatriciaAACI West HillsAAST CAAACO USAAGP Lopez; Patricia West Hills CA USAANM Xue; QiufenAACI Newbury ParkAAST CAAACO USAAGP Xue; Qiufen Newbury Park CA USAANM Yang; BryantAACI Simi ValleyAAST CAAACO USAAGP Yang; Bryant Simi Valley CA US - The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula I, wherein ring A, B | 01-17-2013 |
20130040931 | Amino Heteroaryl Compounds as Beta-Secretase Modulators and Methods of Use - The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula (I); wherein ring A, B | 02-14-2013 |
20140045828 | AMINO-OXAZINES AND AMINO-DIHYDROTHIAZINE COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE - The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula I | 02-13-2014 |
Nick A. Paras, Glendale, CA US
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20100010014 | AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE - The invention relates to aminopyrimidine compounds useful for treating diseases mediated by polo-like kinase 1 (Plk1). The invention also relates to the therapeutic use of such aminopyrimidine compounds and compositions thereof in treating disease states associated with abnormal cell growth and unwanted cell proliferation. | 01-14-2010 |
20110251186 | Amino-Oxazines and Amino-Dihydrothiazine Compounds as Beta-Secretase Modulators and Methods of Use - The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and related conditions. In one embodiment, the compounds have a general Formula I | 10-13-2011 |
20110251190 | SPIRO-TETRACYCLIC RING COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE - The present invention comprises a new class of compounds useful for the modulation of Beta-secretase enzyme activity and for the treatment of Beta-secretase mediated diseases, including Alzheimer's disease (AD) and other related conditions. In one embodiment, the compounds have a general Formula I | 10-13-2011 |
Nick A. Paras, Pacifica, CA US
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20160068545 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN - Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, | 03-10-2016 |
Nick A. Shkumat, Houston, TX US
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20090207966 | IMAGE ACQUISITION FOR DUAL ENERGY IMAGING - Acquisition techniques for dual energy (DE) chest imaging system. Technique factors include the added x-ray filtration, kVp pair, and the allocation of dose between low- and high-energy projections, with total dose equal to or less than that of a conventional chest radiograph. Factors are described which maximize lung nodule detectability as characterized by the signal difference to noise ratio (SDNR) in DE chest images. kVp pair and dose allocation are described using a chest phantom presenting simulated lung nodules and ribs for thin, average, and thick body habitus. Low- and high-energy techniques ranged from 60-90 kVp and 120-150 kVp, respectively, with peak soft-tissue SDNR achieved at [60/120] kVp for patient thicknesses and levels of imaging dose. A strong dependence on the kVp of the low-energy projection was observed. | 08-20-2009 |
Nick A. Shkumat, Hamilton CA
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20080198964 | CARDIAC GATING FOR DUAL-ENERGY IMAGING - Methods are provided for cardiac gating of multiple-energy projection radiographic imaging utilizing an apparatus that measures the patient's peripheral blood perfusion. The choice of methods is dependant on the patient's heart rate and the delays inherent in the imaging system. A first method allows for imaging during the diastole period of the current cardiac cycle. A second method provides an implemented delay to acquire the image during the diastole period of a subsequent cardiac cycle. The use of the apparatus that measures the patient's peripheral blood perfusion allows for an efficient and convenient means of cardiac gating while avoiding occlusion of diagnostically important anatomy. | 08-21-2008 |
Nick A. Siefers, Oak Creek, WI US
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20080287204 | SYSTEM AND METHOD FOR ANALYZING BOWLING BALL MOTION - A system and method for graphically and statistically analyzing and predicting the motion of a bowling ball. In one embodiment, the system includes an automatic precision ball thrower, a computer aided tracking system (“C.A.T.S.”), and a computing device. Certain static properties of the bowling ball are recorded as independent variables. The automatic precision ball thrower is used to throw the bowling ball down the lane a number of times and the C.A.T.S. records various dynamic characteristics of its path. This data is received by the computing device which uses it to calculate a plurality of dependent variables associated with the path of the bowling ball. The computing device relates the independent variables to the dependent variables using multivariable regression analysis, yielding a set of equations which can be used to predict the dependent variables (or dynamic characteristics) of a second bowling ball given a set of independent variables (or static characteristics of the second bowling ball). | 11-20-2008 |