Patent application number | Description | Published |
20100121319 | METHODS AND DEVICES FOR APPLYING ENERGY TO BODILY TISSUES - Devices and methods are disclosed for treating tissue with microwave energy. Such devices and methods are able to treat cavities or surface tissue by creating one or more area or volumetric lesions. Also disclosed are flexible, low-profile devices that can be inserted non-invasively or minimally invasively near or into the target tissue as well as microwave antennas designed to generate ablation profiles that can ablate a large area or a large volume of target tissue in a single ablation. The devices include antennas wherein the field profile generated by an antenna is tailored and optimized for a particular clinical application. The antennas use unique properties of microwaves such as interaction of a microwave field with a metallic object and the use of additional shaping elements to shape the microwave field. | 05-13-2010 |
20100125269 | MICROWAVE TREATMENT DEVICES AND METHODS - The present invention discloses medical systems and methods adapted for the delivery of various medical components such as microwave antennas within or on a body for performing one or more medical procedures. Several embodiments herein disclose medical systems comprising a combination of one or more medical components and one or more elongate steerable or non-steerable arms that are adapted to mechanically manipulate the one or more medical components. Several embodiments of microwave antennas are disclosed that comprise an additional diagnostic or therapeutic modality located on or in the vicinity of the microwave antennas. | 05-20-2010 |
20100137857 | METHODS AND DEVICES FOR APPLYING ENERGY TO BODILY TISSUES - Devices and methods for treating tissue with microwave energy used in applications such as destroying a soft tissue by microwave ablation and/or creating point, line, area or volumetric lesions. Various embodiments of flexible, low-profile devices are also disclosed where such device can be inserted non-invasively or minimally invasively near or into the target tissue such as cardiac tissue. The devices disclosed herein comprise antennas wherein the field profile generated by an antenna is tailored and optimized for a particular clinical application. The antennas use unique properties of microwaves such as interaction of a microwave field with one or more conductive or non-conductive shaping elements to shape or redistribute the microwave field. | 06-03-2010 |
20110004205 | METHODS AND DEVICES FOR DELIVERING MICROWAVE ENERGY - The invention comprises novel microwave antennas wherein the microwave field profile generated by an antenna is tailored and optimized for a particular clinical application. The antennas disclosed herein incorporate one or more additional elements called shaping elements that use unique properties of microwaves such as interaction of a microwave field with one or more conductive or non-conductive elements to shape or redistribute the microwave field. Such shaping elements may be used to reduce the undesired backward coupling of the emitted microwave field to the transmission line. Such shaping elements may be used to increase the power efficiency of the antenna. The invention also discloses devices and methods for treating tissue with microwave energy emitted from the antennas for use in applications such as destroying a soil tissue by microwave ablation. | 01-06-2011 |
20110125145 | DEVICES AND METHODS FOR CREATING CONTINUOUS LESIONS - The present invention discloses devices and methods for creating multiple lesions using ablation devices in anatomical regions such as the heart, for example to treat cardiac arrhythmias. The present invention discloses methods and devices to create continuous lesions using area ablation devices. The present invention discloses various embodiments of reference assemblies for accurately positioning ablation devices having ablating portions, especially deployable ablation portions adapted for area ablation. The ablation devices are positioned using the reference assemblies in the anatomy to create one or more lesions. The present invention also discloses several method embodiments for creating continuous lesions using deployable ablating portions to produce two or more overlapping lesions. | 05-26-2011 |
20130256302 | RETURNED POWER FOR MICROWAVE APPLICATIONS - The present invention related to devices and methods that use returned power (RP) measurements during microwave energy delivery to perform one or more functions. For example, microwave devices and systems that comprise one or more features to measure the returned microwave power. One or more measurements of the returned microwave power may be used to obtain information about one or more of: antenna shape, system status and system performance. One or more measurements of the returned microwave power shaping elements may also be used to obtain information about one or more properties of the target material. The invention also discloses devices and methods for delivering microwave energy to a variety of target materials to achieve a variety of desired microwave effects. | 10-03-2013 |
20140187895 | DELIVERY SYSTEM FOR DELIVERING A MEDICAL DEVICE TO A LOCATION WITHIN A PATIENT'S BODY - Devices, systems and methods are provided for deployment of one or more functional devices, such as therapeutic and/or diagnostic medical devices and/or positioning devices, at various locations relative to a defined operative path. The devices, systems, and methods can include a guide system and a positioning element. The guide system defines the operative path when deployed within a patient's body. The positioning element cooperates with the guide system to define one or more positions relative the defined operative path from which the one or more functional devices are deployed. The present inventions allow for the accurate and reliable placement of the one or more functional devices at the one or more positions relative the operative path. In one embodiment, the functional device is an ablation device adapted to ablate cardiac tissue for the treatment of cardiac arrhythmias, such as atrial fibrillation. | 07-03-2014 |
20140190960 | RETURNED POWER FOR MICROWAVE APPLICATIONS - The present invention related to devices and methods that use returned power (RP) measurements during microwave energy delivery to perform one or more functions. For example, microwave devices and systems that comprise one or more features to measure the returned microwave power. One or more measurements of the returned microwave power may be used to obtain information about one or more of: antenna shape, system status and system performance. One or more measurements of the returned microwave power shaping elements may also be used to obtain information about one or more properties of the target material. The invention also discloses devices and methods for delivering microwave energy to a variety of target materials to achieve a variety of desired microwave effects. | 07-10-2014 |
20140358140 | MICROWAVE TREATMENT DEVICES AND METHODS - The present invention discloses embodiments of microwave antennas and other energy delivery systems. The present invention also discloses systems and methods for the delivery of various medical components within or on a body for performing one or more medical procedures. Several embodiments herein disclose medical systems comprising a combination of one or more medical components and one or more elongate steerable or non-steerable arms that are adapted to mechanically manipulate the one or more medical components. Several embodiments of microwave antennas are disclosed that comprise an additional diagnostic or therapeutic modality located on or in the vicinity of the microwave antennas. | 12-04-2014 |
Patent application number | Description | Published |
20100122269 | Supervisory Process Control And Manufacturing Information System Application Having A Layered Architecture - A supervisory process control and manufacturing information system application is disclosed. The components of the application are distributable to a plurality of networked computer devices in a multi-layered hierarchical manner wherein lower layers host higher installed layers of application components. Application objects reside at a relatively high level of the distributed application architecture and model entities within a process control system. Engine objects host execution of the application objects in a run-time environment. Thus, application objects are not deployed until a host engine object with which they are associated have been deployed. Engine objects are hosted by platform objects. The platform objects correspond to a physical computer system component for executing the engine objects and associated application objects. A configuration facility presents a variety of views including deployment and model views of the application. The views incorporate the relationships of the objects that make up the distributed application. | 05-13-2010 |
20100211928 | Supervisory Process Control And Manufacturing Information System Application Having An Extensible Component Model - A template-based supervisory process control and manufacturing information application development facility is disclosed that includes a number of time-saving application development tools that significantly enhance design productivity and allow re-using of previously developed application building blocks. The development facility includes an application object template library that stores a set of previously defined application object templates. The template library is accessed by developers through a configuration utility that facilitates specifying instances of the set of previously defined application object templates to be included in an application. Thereafter, application objects are instantiated from the selected ones of the set of previously defined application object templates in a build of the specified application. | 08-19-2010 |
20110172965 | Remotely Monitoring/Diagnosing Distributed Components Of A Supervisory Process Control And Manufacturing Information Application From A Central Location - A centralized diagnostics management tool is disclosed that facilitates centralized monitoring of distributed components of a supervisory process control and manufacturing information application. The centralized diagnostics management tool includes a diagnostics management console shell that is customized according to a set of software modules that interface to data sources to populate views supported by the console shell. The console shell includes a set of view templates including controls for manipulating graphically displayed representations of data rendered by the distributed components. The console shell also includes an interface for exchanging requests and data with an extensible set of software modules that provide data links to ones of the set of distributed components. The software modules also define the customizable portions of the view rendered by the console shell. | 07-14-2011 |
20130139227 | Security Architecture For A Process Control Platform Executing Applications - A security component within a supervisory process control and manufacturing information system comprising a set of user roles corresponding to different types of users within the information system, a set of security groups defining a set of security permissions with regard to a set of objects, wherein each security group includes an access definition relating the security permissions to at least one of the set of user roles, and a set of user accounts assigned to at least one of the defined roles thereby indirectly defining access rights with regard to the set of objects having restricted access within the system. The security permissions within the supervisory process control and manufacturing information system are assigned at an object attribute level. | 05-30-2013 |
20130261773 | SUPERVISORY PROCESS CONTROL AND MANUFACTURING INFORMATION SYSTEM APPLICATION HAVING AN EXTENSIBLE COMPONENT MODEL - A template-based supervisory process control and manufacturing information application development facility is disclosed that includes a number of time-saving application development tools that significantly enhance design productivity and allow re-using of previously developed application building blocks. The development facility includes an application object template library that stores a set of previously defined application object templates. The template library is accessed by developers through a configuration utility that facilitates specifying instances of the set of previously defined application object templates to be included in an application. Thereafter, application objects are instantiated from the selected ones of the set of previously defined application object templates in a build of the specified application. | 10-03-2013 |
20130298139 | INTERNATIONALIZATION OF OBJECTS EXECUTABLE IN A SUPERVISORY PROCESS CONTROL AND MANUFACTURING INFORMATION SYSTEM - An application object for a supervisory process control and manufacturing information system application distributable to a plurality of networked computer devices and having a layered architecture, the application object comprising a set of text entries listed in a first language, a dictionary within each object drafted to enable the set of text entries to be translated into a plurality of multiple languages, and a set of one or more translation fields for storing text in each of the plurality of languages corresponding to the set of text entries listed in the first language. | 11-07-2013 |
20140189788 | Security Architecture For A Process Control Platform Executing Applications - A security component within a supervisory process control and manufacturing information system comprising a set of user roles corresponding to different types of users within the information system, a set of security groups defining a set of security permissions with regard to a set of objects, wherein each security group includes an access definition relating the security permissions to at least one of the set of user roles, and a set of user accounts assigned to at least one of the defined roles thereby indirectly defining access rights with regard to the set of objects having restricted access within the system. The security permissions within the supervisory process control and manufacturing information system are assigned at an object attribute level. | 07-03-2014 |
20150039112 | SUPERVISORY PROCESS CONTROL AND MANUFACTURING INFORMATION SYSTEM APPLICATION HAVING AN EXTENSIBLE COMPONENT MODEL - A template-based supervisory process control and manufacturing information application development facility is disclosed that includes a number of time-saving application development tools that significantly enhance design productivity and allow re-using of previously developed application building blocks. The development facility includes an application object template library that stores a set of previously defined application object templates. The template library is accessed by developers through a configuration utility that facilitates specifying instances of the set of previously defined application object templates to be included in an application. Thereafter, application objects are instantiated from the selected ones of the set of previously defined application object templates in a build of the specified application. | 02-05-2015 |
Patent application number | Description | Published |
20100076890 | GUI-BASED WALLET PROGRAM FOR ONLINE TRANSACTIONS - Provided is a method and a GUI-based software application that acts as a wallet with network interconnectivity for enabling a user to securely and seamlessly conduct transactions with his or her online financial transaction program by means of a computer or a wireless handheld device without having to depend on an Internet browser. | 03-25-2010 |
20100082468 | FUNDING ON-LINE ACCOUNTS - A system generates an identifier when a consumer deposits cash, where a new unique identifier is generated with each transaction. The consumer receives the identifier and the identifier (along with the amount of cash deposit) is communicated to a payment provider for storage. The consumer may then access and fund an on-line account with the financial services provider by first accessing the account and entering the unique character identifier, which the system processes. If the identifier is valid, e.g., an actual stored identifier within the system associated with a cash amount, then the system transfers that amount to the consumer's account. At this point, the consumer may use the account to make an on-line transaction or purchase with the newly funded amount. | 04-01-2010 |
20110087597 | FUNDING ON-LINE ACCOUNTS - A system generates an identifier when a consumer deposits cash, where a new unique identifier is generated with each transaction. The consumer receives the identifier and the identifier (along with the amount of cash deposit) is communicated to a payment provider for storage. The consumer may then access and fund an on-line account with the financial services provider by first accessing the account and entering the unique character identifier, which the system processes. If the identifier is valid, e.g., an actual stored identifier within the system associated with a cash amount, then the system transfers that amount to the consumer's account. At this point, the consumer may use the account to make an on-line transaction or purchase with the newly funded amount. | 04-14-2011 |
20150248675 | FUNDING ON-LINE ACCOUNTS - A system generates an identifier when a consumer deposits cash, where a new unique identifier is generated with each transaction. The consumer receives the identifier and the identifier (along with the amount of cash deposit) is communicated to a payment provider for storage. The consumer may then access and fund an on-line account with the financial services provider by first accessing the account and entering the unique character identifier, which the system processes. If the identifier is valid, e.g., an actual stored identifier within the system associated with a cash amount, then the system transfers that amount to the consumer's account. At this point, the consumer may use the account to make an on-line transaction or purchase with the newly funded amount. | 09-03-2015 |
Patent application number | Description | Published |
20110086866 | INHIBITORS OF BRUTON'S TYROSINE KINASE - Described herein are kinase inhibitor compounds, methods for synthesizing such inhibitors, and methods for using such inhibitors in the treatment of diseases. Further described herein are methods, assays and systems for determining an appropriate inhibitor of a protein, including a kinase. | 04-14-2011 |
20110311624 | FORMULATIONS OF HISTONE DEACETYLASE INHIBITOR AND USES THEREOF - Dosing regimens, methods of treatment, controlled release formulations, and combination therapies that include an HDAC inhibitor, or a pharmaceutically acceptable salt thereof, are described. | 12-22-2011 |
20120087915 | USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) - Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile. | 04-12-2012 |
20120100138 | THE USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) - Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile. | 04-26-2012 |
20120183535 | USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) - Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile. | 07-19-2012 |
20130018032 | INHIBITORS OF BRUTON'S TYROSINE KINASE - Described herein are kinase inhibitor compounds, methods for synthesizing such inhibitors, and methods for using such inhibitors in the treatment of diseases. Further described herein are methods, assays and systems for determining an appropriate inhibitor of a protein, including a kinase. | 01-17-2013 |
20130195852 | USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) - Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile. | 08-01-2013 |
20130202611 | USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) - Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile. | 08-08-2013 |
20130273030 | USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) - Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile. | 10-17-2013 |
20130310402 | USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) - Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile. | 11-21-2013 |
20140057862 | FORMULATIONS OF HISTONE DEACETYLASE INHIBITOR AND USES THEROF - Dosing regimens, methods of treatment, controlled release formulations, and combination therapies that include an HDAC inhibitor, or a pharmaceutically acceptable salt thereof, are described. | 02-27-2014 |
20140080844 | INHIBITORS OF BRUTON'S TYROSINE KINASE - Described herein are kinase inhibitor compounds, methods for synthesizing such inhibitors, and methods for using such inhibitors in the treatment of diseases. Further described herein are methods, assays and systems for determining an appropriate inhibitor of a protein, including a kinase. | 03-20-2014 |
20140194446 | USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) - Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile. | 07-10-2014 |
20140303191 | USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) - Methods are provided for treating a hematologic cancer comprising administering an anticancer agent to a subject identified as having an increased mobilization of a subpopulation of lymphocytes from a malignancy following administration of an irreversible Btk inhibitor. Methods also are provided for identification of subjects for treatment and the analysis of cells mobilized from a hematologic malignancy following administration of an irreversible Btk inhibitor. | 10-09-2014 |
20140341989 | FORMULATIONS OF HISTONE DEACETYLASE INHIBITOR IN COMBINATION WITH BENDAMUSTINE AND USES THEREOF - Dosing regimens, methods of treatment, controlled release formulations, and combination therapies that include bendamustine, or a pharmaceutically acceptable salt thereof and an HDAC inhibitor, or a pharmaceutically acceptable salt thereof, are described. | 11-20-2014 |
20140371241 | TEC FAMILY KINASE INHIBITOR ADJUVANT THERAPY - Described herein are methods and compositions comprising a covalent TEC family kinase inhibitor for use in adjuvant therapy, including adjuvant cancer therapy, vaccination and treatment of immune disorders and pathogenic infections. | 12-18-2014 |
20150031710 | USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) - Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile. | 01-29-2015 |
20150031711 | USE OF INHIBITORS OF BRUTON'S TYROSINE KINASE (BTK) - Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile. | 01-29-2015 |
20150111912 | INHIBITORS OF BRUTON'S TYROSINE KINASE - Described herein are kinase inhibitor compounds, methods for synthesizing such inhibitors, and methods for using such inhibitors in the treatment of diseases. Further described herein are methods, assays and systems for determining an appropriate inhibitor of a protein, including a kinase. | 04-23-2015 |