Milan, US
Aileen Milan, San Diego, CA US
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20090176976 | NITRILASES - The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature. | 07-09-2009 |
20100086986 | Nitrilases and Methods for Making and Using Them - The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature. | 04-08-2010 |
20100273659 | Nitrilases, Nucleic Acids Encoding Them and Methods for Making and Using Them - The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature. | 10-28-2010 |
20110263839 | Nucleic Acids Encoding Nitrilases - The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature. | 10-27-2011 |
20120010104 | GROWTH SELECTION METHOD - The invention provides growth selection methods for screening an environmental or a mixed population library of nucleic acids comprising uncharacterized nucleic acids for the presence of a nucleic acid encoding an enzyme of interest. In one aspect, methods for screening and identification of enzymes, e.g., transaminases, nitrilases, aldolases, epoxide hydrolases are provided. Methods for the production and screening of gene libraries generated from nucleic acids isolated from more than one organism for enzymes of interest, e.g., transaminases, nitrilases, aldolases, epoxide hydrolases, are also provided. | 01-12-2012 |
20130177949 | NITRILASES - The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature. | 07-11-2013 |
David J. Milan, Newton, MA US
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20130310351 | Treating Long QT Syndrome - This document relates to compounds useful for treating cardiac arrhythmias, for example, long QT syndrome. Also provided herein are methods and materials for using such compounds to shorten myocardial repolarization time in a patient. | 11-21-2013 |
Giulio Milan, Northville, MI US
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20140268480 | HIGH VOLTAGE CONNECTION SEALING METHOD FOR CORONA IGNITION COIL - A corona igniter assembly | 09-18-2014 |
Henry Milan, Rochester, MI US
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20080215775 | UNIVERSAL SERIAL BUS HUB WITH WIRELESS COMMUNICATION TO REMOTE PERIPHERAL DEVICES - A wireless USB hub for connecting a plurality of remote peripheral devices to a computer for communication therewith without the need to physically connect the peripheral devices to the hub via a cable connection. The wireless USB hub includes a receiver for receiving wireless data transmissions from one or more remote peripheral devices. The wireless USB hub further includes a hub controller for passing appropriate peripheral device information to a USB upstream port and then to a computer. | 09-04-2008 |
20080293274 | SELECTIVE FLASH MEMORY DRIVE WITH QUICK CONNECTOR - A flash memory device having a housing for enclosing a flash memory drive, a host chip for selectively operating the flash memory drive in a host mode or a slave mode, and a control chip for controlling the operations of the flash memory device. The flash memory device further includes a universal connector mounted in the housing and configured for electrical connection to enable the connection of the flash memory device to at least one peripheral device. The flash memory device also preferably including a display screen and interface control for user operations of the device. | 11-27-2008 |
20100218042 | UNIVERSAL SERIAL BUS HUB WITH WIRELESS COMMUNICATION TO REMOTE PERIPHERAL DEVICES - A wireless USB hub for connecting a plurality of remote peripheral devices to a computer for communication therewith without the need to physically connect the peripheral devices to the hub via a cable connection. The wireless USB hub includes a receiver for receiving wireless data transmissions from one or more remote peripheral devices. The wireless USB hub further includes a hub controller for passing appropriate peripheral device information to a USB upstream port and then to a computer. | 08-26-2010 |
20120102372 | UNIVERSAL SERIAL BUS HUB WITH WIRELESS COMMUNICATION TO REMOTE PERIPHERAL DEVICES - A wireless USB hub for connecting a plurality of remote peripheral devices to a computer for communication therewith without the need to physically connect the peripheral devices to the hub via a cable connection. The wireless USB hub includes a receiver for receiving wireless data transmissions from one or more remote peripheral devices. The wireless USB hub further includes a hub controller for passing appropriate peripheral device information to a USB upstream port and then to a computer. | 04-26-2012 |
James Edward Milan, Buxton, ME US
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20120300205 | METHOD OF NORMALIZING A FLUORESCENCE ANALYZER - A method of normalizing an analyzer response value of a fluorescence analyzer is provided. The method includes measuring an excitation spectrum of the analyzer and measuring an emission sensitivity spectrum of the analyzer. Next, a normalization factor based at least in part upon the excitation spectrum of the analyzer and the emission sensitivity spectrum of the analyzer is determined. The sample is then analyzed to obtain an uncorrected analyzer response value. A normalized analyzer response value is calculated based at least in part upon the uncorrected analyzer response value and the normalization factor. | 11-29-2012 |
Jennifer Milan, Westminister, CO US
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20150364022 | ALARM FATIGUE MANAGEMENT SYSTEMS AND METHODS - An apparatus for modifying alarms at a medical device for alarm fatigue management is provided and includes an alarm monitor, an alarm filter, an alarm modifier, a memory element for storing data, and a processor that executes instructions associated with the data, wherein the processor and the memory element cooperate such that the apparatus is configured for receiving an alarm condition from an alarm management engine, the alarm condition based on an alarm fatigue level of a user of the medical device, the alarm fatigue level based on at least a user fatigue model, a medical device model and a patient condition, receiving an alarm from the medical device, modifying the alarm according to the alarm condition, the alarm condition being configured to increase a likelihood of the user responding to the modified alarm, and generating an alarm indicator based on the modification. | 12-17-2015 |
Jose Ortillio Milan, Greensboro, NC US
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20090306166 | Method of Controlling Phytopathogenic Diseases on Turfgrass - A method of controlling phytopathogenic diseases on turfgrass or on seeds thereof, which comprises applying to the turfgrass, the locus thereof or seeds thereof a composition, that, in addition to formulation adjuvants, comprises a fungicidally effective amount of at least one compound of formula I | 12-10-2009 |
Jose Otilio Milan, Greensboro, NC US
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20120225921 | METHOD OF CONTROLLING PHYTOPATHOGENIC DISEASES ON TURFGRASS - A method of controlling phytopathogenic diseases on turfgrass or on seeds thereof, which comprises applying to the turfgrass, the locus thereof or seeds thereof a composition, that, in addition to formulation adjuvants, comprises a fungicidally effective amount of at least one compound of formula I | 09-06-2012 |
Joseph Milan, Mercer Island, WA US
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20130063495 | THUMBNAIL ZOOM - File exploration is facilitated by enabling zoom with respect to a thumbnail as a function of an identified point of interest. More particularly, a scaled thumbnail of the same size as a thumbnail can be presented as a function of an identified point of interest. Furthermore, navigation, among other things, is enabled to allow panning with respect to a scaled thumbnail, for instance. | 03-14-2013 |
Joseph Dallas Milan, Mercer Island, WA US
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20130229429 | Deterministic Visual Indication of User Data Context - A VCI (visual context indicator) color is assigned deterministically and proactively at runtime to user data contexts, and is not stored in the database, spreadsheet, or other context. VCI colors can be high contrast friendly colors. The same color is assigned to a given context each time the application runs unless the context's identifying property has changed. Color assignments are not made by users or by the application's designer, but are done instead by hashing from a context's identifying property into a VCI color palette containing, e.g., eight to sixteen colors. Unlike text-selection coloring, VCI coloring is based on the user data context's identifying property. The color assignment visually indicates context by displaying the context's name in the VCI color, or by displaying a graphical element in the VCI color near the context name. VCI color assignment also shows the occurrence and result of changes in user data context. | 09-05-2013 |
20150082245 | Deterministic Visual Indication of User Data Context - A VCI (visual context indicator) color is assigned deterministically and proactively at runtime to user data contexts, and is not stored in the database, spreadsheet, or other context. VCI colors can be high contrast friendly colors. The same color is assigned to a given context each time the application runs unless the context's identifying property has changed. Color assignments are not made by users or by the application's designer, but are done instead by hashing from a context's identifying property into a VCI color palette containing, e.g., eight to sixteen colors. Unlike text-selection coloring, VCI coloring is based on the user data context's identifying property. The color assignment visually indicates context by displaying the context's name in the VCI color, or by displaying a graphical element in the VCI color near the context name. VCI color assignment also shows the occurrence and result of changes in user data context. | 03-19-2015 |
Jucovic Milan, Durham, NC US
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20110023194 | ENGINEERING ZYMOGEN FOR CONDITIONAL TOXICITY - The ADP-ribosyltransferase, Vip2, exerts its intracellular toxicity in insects by modifying actin and preventing actin polymerization. Due to the nature of this toxin, expression of Vip2 in planta is lethal to the plant. Described herein are methods of making zymogens of toxic proteins that are benign in a non-target organism and are activated in a target organism. Disclosed herein are methods of engineering a random propeptide library at a terminus of a toxic protein and selecting for malfunctional variants in yeast. Using this method a selected proenzyme possesses reduced enzymatic activity as compared to the wild-type Vip2 protein, but remains a potent toxin towards corn rootworm larvae. The Vip2 zymogen can be proteolytically activated by corn rootworm digestive proteases. | 01-27-2011 |
Lucic Milan, East Windsor, CT US
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20140169944 | Debris Filter for Motor Cooling Inlet on Ram Air Fan - A ram air fan has a fan impeller and a motor. The impeller and motor are mounted within a housing. An inlet header delivers air to an inlet for the fan. An air supply system delivers air from an internal cavity of the inlet header to the motor and air bearings. The air supply system includes a conduit extending through the housing. A connection from the conduit extends from a J-shaped tube mounted within the inlet header. The J-shaped tube extends to a remote end, with a perforated member positioned on the remote end. | 06-19-2014 |
Mariana Milan, Hackettstown, NJ US
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20150327550 | ENVIRONMENT-FRIENDLY, BIODEGRADABLE, VOC-FREE, NON-CORROSIVE AQUEOUS SOLUTION OF 1, 2-BENZISOTHIAZOLIN-3-ONE (BIT) AND PROCESS FOR PREPARING THE SAME - What is described herein is an environment-friendly, biodegradable, non-corrosive aqueous solution of isothiazolin-3-one comprising: (i) at least about 5 wt. % to about 50 wt. % of 1,2-benzisothiazolin-3-one (BIT); (ii) about 5 wt. % to 15 wt. % of neutralizing agent; (iii) about 0.01 wt. % to about 20 wt. % of at least one biodegradable chelating agent; (iv) about 0.01 wt. % to about 20 wt. % of at least one alkyl polyglucoside, a solubilizer; (v) about 0.1 wt. % to about 2.0 wt. % of polyvinyl alcohol (PVA), a crystal modifier; and (vi) about 50% to about 85% by wt. of water; and wherein said aqueous solution is free from volatile organic compounds (VOC's), glycerols, polyglycerols, derivatives of glycerols, glycols, polyglycols and/or derivatives of glycols, and wherein, the frozen aqueous solution of isothiazolin-3-one is capable of completely thawing within two hours at room temperature or at about 25° C. to about 30° C. | 11-19-2015 |
Michael Milan, Bethesda, MD US
Michael Milan, Chantilly, VA US
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20140117030 | Beverage Container Lid - A beverage container lid includes an interior cover, an exterior cover, and a hinge connecting the interior cover to the exterior cover. The beverage container is versatile in that it may be adapted for use with a beverage container containing a cold beverage, a hot beverage, or a foamy or creamy beverage. The beverage container lid preferably includes a spout, straw perforations, an elevated portion, a reservoir bottom, a well portion, and a pair of retaining walls preventing direct flow of beverage from a pair of openings in the interior cover to the spout. Methods of use and methods of making a the beverage container lid are also described. | 05-01-2014 |
Michael Milan, Lisbon, OH US
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20130264353 | APPARATUS FOR MIXING, COOLING, AND DISPENSING A CONTAINERIZED BEVERAGE - A smoothie dispenser ( | 10-10-2013 |
Michael Milan, South Riding, VA US
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20150305531 | BEVERAGE CONTAINER LID - A beverage container lid includes an interior cover, an exterior cover, and a hinge connecting the interior cover to the exterior cover. The beverage container is versatile in that it may be adapted for use with a beverage container containing a cold beverage, a hot beverage, or a foamy or creamy beverage. The beverage container lid preferably includes a spout, straw perforations, an elevated portion, a reservoir bottom, a well portion, and a pair of retaining walls preventing direct flow of beverage from a pair of openings in the interior cover to the spout. Methods of use and methods of making a beverage container lid are also described. | 10-29-2015 |
Michael Milan, Raleigh, NC US
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20130214013 | Adaptor and Tips for Caulking Tubes - A dispensing adaptor is disclosed for tubes of high viscosity compositions. The adaptor includes an adaptor body, the interior of which defines a tube tip receiving opening having a size and shape corresponding to the tip of a tube of high viscosity composition, an adapter tip on the adaptor body through which the tip receiving opening continues, a custom tip for the adapter tip that fits on the adapter tip, and at least two sets of custom tip attachments on the adapter body. | 08-22-2013 |
Michael Milan, Potomac, MD US
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20090108006 | Beverage container lid having liquid cooling effect - Disclosed is a lid for a beverage container including external and internal covers, which may be coupled together to define a cooling reservoir there between to receive and cool hot liquids that may be held in the beverage container. The external cover having ventilation holes and a dispensing spout for dispensing the liquid therein to the user. The internal cover includes a plurality of walls used for directed the hot liquid that enters from the beverage container. A plurality of entrance apertures are disposed in the interior cover, allowing the hot liquid to enter the reservoir. A plurality of dispensing walls cooperate to direct the hot liquid entering through the entrance apertures and to separate the hot liquid from cooled liquid exiting the reservoir through a dispensing aperture disposed in the spout. | 04-30-2009 |
Sandra Milan, Orinda, CA US
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20150335650 | METHODS OF TREATING PR-POSITIVE, LUMINAL A BREAST CANCER WITH PI3K INHIBITOR, PICTILISIB - Methods and compositions are provided for treating breast cancer in patients with a PI3K inhibitor, GDC-0941 in combination with an endocrine therapy agent. | 11-26-2015 |
Terri Milan, Austin, TX US
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20100242199 | Wearable Footwear-Based Cleaning Apparatus - A wearable cleaning apparatus includes a sole incorporating a fastening system, the fastening system including a bottom surface configured to enable secure attachment of one or more alternate bottom portions, the one or more alternate bottom portions including at least one bottom surface configured for cleaning one or more surfaces; and an upper foot receiving portion integrally extending from the sole to form a foot receiving portion of the wearable cleaning apparatus. | 09-30-2010 |
Trcka Milan, Northridge, CA US
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20100298825 | Treatment System With A Pulse Forming Network For Achieving Plasma In Tissue - A system for providing electrical energy to tissue to treat the tissue, including a pair of output electrodes for delivering the electrical energy to the tissue, a pulse forming network for generating short high voltage pulses of electrical energy; an isolation transformer disposed between the pulse forming network and the pair of output electrodes to deliver the short high voltage pulses of electrical energy from the pulse forming network to the pair of output electrodes and to provide voltage isolation between the pulse forming network and the electrodes, and a common mode choke disposed between the isolation transformer and the pair of output electrodes to keep the pulse current flowing out from the first electrode approximately equal to the pulse current flowing back into the second electrode to substantially reduce stray or leakage currents in the tissue. The high voltage pulses of electrical energy may be about 100 to 400 nanoseconds in duration and about 10 kilovolts to about 20 kilovolts in initial peak magnitude. Related methods are also disclosed. | 11-25-2010 |