Michels, DE
André Michels, Borgentreich DE
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20100116839 | Roller storage system - A roller storage system is described consisting of a storage roller (200) for storing banknotes, where the storage roller (200) is operated in a money processing system. The roller storage system is characterized in that | 05-13-2010 |
20120217130 | DEVICE FOR HANDLING VALUE NOTES - The invention relates to a device ( | 08-30-2012 |
20130036951 | APPARATUS FOR TRANSPORTING AND/OR STORING BANKNOTES - The invention relates to a device ( | 02-14-2013 |
André Michels, Borgentreich DE
Patent application number | Description | Published |
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20100116839 | Roller storage system - A roller storage system is described consisting of a storage roller (200) for storing banknotes, where the storage roller (200) is operated in a money processing system. The roller storage system is characterized in that | 05-13-2010 |
Andrè Michels, Borgentreich-Grosseneder DE
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20110017766 | Roller storage system - A roller storage system ( | 01-27-2011 |
20120205221 | DEVICE AND METHOD FOR HANDLING VALUE NOTES - The invention relates to a device ( | 08-16-2012 |
Andrè Michels, Borgentreich-Grosseneder DE
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20100072220 | Optimised Guidance Of Documents In Self-Service Systems - A roller storage system for storing sheet-type objects, in particular bank notes, is proposed, comprising a first film drum ( | 03-25-2010 |
20100133289 | ROLLER STORAGE SYSTEM FOR SHEET-TYPE OBJECTS - A roller storage system is proposed for storing sheet-like items, especially bank notes, comprising at least one film drum ( | 06-03-2010 |
20110017766 | Roller storage system - A roller storage system ( | 01-27-2011 |
20150021385 | CASH BOX WITH DUAL-ROLL STORAGE SYSTEM - The invention relates to a cash box ( | 01-22-2015 |
Andreas Michels, Duesseldorf DE
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20090258406 | Use of esterases for separating plastics - The invention relates to agents containing esterases, and to the use thereof for dressing fibres, in particular, artificial fibres, washing and cleaning agents comprising esterases and corresponding washing and cleaning methods, in addition to additional technical areas of application. The invention also relates to the use of esterases for protecting against or reducing and/or preventing pilling, preferably in textiles, particularly plastic fibres, more preferably polyester fibres, in addition to the use of esterases for separating the plastics, in particular, polyester compounds. The invention further relates to novel esterases and to sufficiently related proteins and to derivatives thereof, agents containing them and to the use thereof. | 10-15-2009 |
20100062964 | Benzophenone or Benzoic Acid Anilide Derivatives containing Carboxyl Groups as Enzyme Stabilizers - Washing and cleaning agents containing benzophenone or benzole anilide derivatives containing carboxyl groups, which function as protease inhibitors and are suitable as enzyme stabilizers. Additional subjects are the use of such compounds as reversible inhibitors of a protease and consequently for a washing or cleaning agent formulation, and additional methods and uses relating thereto. | 03-11-2010 |
Andreas Michels, Walzbachtal DE
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20110317274 | COUPLING DEVICE FOR DETACHABLY CONNECTING AN EYEPIECE OF AN ENDOSCOPE OPTICAL SYSTEM WITH A CAMERA LENS - A coupling device for detachably connecting an eyepiece of an endoscope optical system with a camera lens includes a receptacle for the eyepiece, attachment means for securing the eyepiece in the receptacle, and a manually activated handle arranged on the outside for releasing the attachment. The attachment means are controlled by the eyepiece so as to automatically attach the eyepiece in the receptacle while introducing the eyepiece into the receptacle. | 12-29-2011 |
Andreas Michels, Dusseldorf DE
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20100210502 | Polycyclic Compounds as Enzyme Stabilizers - The present invention relates to laundry and cleaning agents containing polycyclic compounds that act as protease inhibitors and are therefore suitable enzyme stabilizers. | 08-19-2010 |
20100227789 | Washing Agent having Stabilized Enzymes - The present application relates to washing and cleaning agents, containing phosphate compounds having aliphatic and/or aromatic residues, which act as enzyme stabilizers. Further subjects are the use of such compounds as reversible inhibitors of enzymes, in particular of proteolytic enzymes, and thus as stabilizers in washing or cleaning agents, and further methods and uses correlated therewith | 09-09-2010 |
Antje Michels, Dortmund DE
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20090278038 | Method and device for generating positively and/or negatively ionized gas analytes for gas analysis - A solution is supposed to be created with a method for generating positively and/or negatively ionized gas analytes for gas analysis in an ion mobility spectrometer or in a mass spectrometer, with which method the gas analyte can be ionized without the restrictions of previous ionization methods for gas analysis in an ion mobility spectrometer or in a mass spectrometer, forming positive and/or negative ions. | 11-12-2009 |
Christoph Michels, Saarbrucken DE
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20140377122 | CAST IRON MATERIAL AND MOTOR VEHICLE PART MADE OF THE CAST IRON MATERIAL - The invention relates to a cast iron material with lamellar graphite formation. It further relates to a motor vehicle part made of the cast iron material. | 12-25-2014 |
Daniel Michels, Reutlingen DE
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20140231976 | METHOD FOR PRODUCING A SOLDER JOINT - The invention relates to a method for producing a solder joint between at least one base part ( | 08-21-2014 |
Dirk Michels, Aachen DE
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20150051436 | INTRAVASCULAR BLOOD PUMP - An intravascular blood pump having a drive section ( | 02-19-2015 |
Erhard Michels, Stade DE
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20150225566 | POLYURETHANE CASTING RESINS AND POTTING COMPOUNDS PRODUCED THEREFROM - The invention relates to polyurethane casting resins for producing polyurethane potting compounds, which can be obtained from a reaction mixture of polyisocyanates, polyepoxides, polyols, latent catalysts and optionally additives. The invention also relates to a method for producing said compounds. | 08-13-2015 |
Erhard Michels, Koln DE
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20080319096 | POLYISOCYANATES AND POLYURETHANES CONTAINING POLYMER MODIFIERS AND THEIR USE - The invention relates to polymer-modified polyisocyanates and to polyurethanes prepared therefrom, and to their use in the production of polyurethane molded bodies. The polyisocyanates are modified with thermoplastic vinyl polymers having a number average molecular weight of from 15 to 90 kg/mol. | 12-25-2008 |
20100280212 | POLYMER DISPERSIONS IN POLYESTER POLYOLS - The present invention relates to polymer dispersions in polyester polyols, a process for producing them and their use for the production of polyurethanes, in particular microcellular polyurethanes. These polyester polyols have sulfur atoms and are free of olefinically unsaturated groups. | 11-04-2010 |
Erwin Michels, Kail DE
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20080245179 | Pedal simulation device - The invention relates to a pedal simulation device for simulating the reaction behaviour of a pedal, in particular of a brake pedal of a vehicle brake system, comprising a cylinder, a piston disposed displaceably inside the cylinder and coupled to the pedal and delimiting a working chamber inside the cylinder, a resetting element which, upon an actuation of the pedal, exerts a resetting force on the pedal, and a modelling device, which is fluidically connected to the working chamber, for influencing the reaction behaviour of the pedal. In the invention, for achieving the reaction behaviour it is provided that, upon an actuation of the pedal, by means of the modelling device a vacuum, which is arising or has arisen in the working chamber, is built up. | 10-09-2008 |
20100244547 | BRAKE EQUIPMENT FOR A LAND VEHICLE - Brake equipment comprising a hydraulic, single- or multi-circuit braking system of a land vehicle having an electric drive for executing a regenerative braking of the land vehicle by means of at least one electric machine in or on the drive train of the vehicle and also a braking of the land vehicle by means of at least one wheel brake. A brake pedal and at least one sensor are used to detect a braking requirement of the driver. A master cylinder is used to supply pressurized hydraulic fluid into at least one brake circuit that supplies at least one wheel brake in accordance with the braking requirement. Associated with at least one brake circuit is an electrohydraulic control unit comprising at least a first connection for hydraulic fluid and at least a second connection for hydraulic fluid. An electronic control unit controls components of the electrohydraulic control unit such as a hydraulic pump and switching valves as a function of a braking requirement and/or sensor signals that represent ambient quantities or characteristic quantities coming from the braking system. A regenerative brake unit has at least a first connection for hydraulic fluid and at least a second connection for hydraulic fluid and is hydraulically coupled into at least one of the brake circuits between the master cylinder and at least one of the wheel brakes. The regenerative brake unit is actuated by the electronic control unit to bring about the effect that, in the event of a regenerative braking operation, the volume of hydraulic fluid corresponding to the braking requirement is not supplied into the wheel brakes, but is stored. | 09-30-2010 |
Frank Michels, Kleve DE
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20110256997 | FOLDING METHOD AND APPARATUS FOR MAKING A CARTON - An apparatus for making a box from a foldable blank having a central polygonal floor panel and a plurality of outwardly projecting side panels has a frame, a supply on the frame holding the blank, a folder on the frame above the supply, and a feeder having a grab engageable with the blank in the supply and movable to a position above the folder. The feeder picks up the blank with the grab, moves the picked-up blank and grab up to above the folder, and deposits the picked-up blank in the folder that folds the deposited blank into a box. | 10-20-2011 |
20110286825 | APPARATUS FOR LIFTING A GROUP OF CONTAINERS OR THE LIKE - An array of objects stands on a flexible web on a horizontal support, and a frame at the accumulation region gathers the objects at the downstream end into a group having a plurality of transverse rows. A transport element formed as a blind has an end edge and is shifted shiftable atop the web upstream in the direction between a ready position with the end edge spaced from the group standing on the web and a pickup position underlying the entire group. A lifting element underneath the web moves jointly with the transport element such that the web is raised immediately upstream of the end edge of the transport element to raise downstream edges of the objects and the transport element is engageable between the objects in the group and the web so the transport element can slide underneath the objects in the group. | 11-24-2011 |
20140373483 | PACKAGING METHOD AND APPARATUS - An apparatus for wrapping a stack of objects vertical side faces and a horizontal top face has a unit for wrapping a film wrapper around the stack such that respective sections of the wrapper extend upward from each of the side faces. A first welder welds ends the film wrapper together at one of the side faces of the stack. A fold-over device folding the film sections over onto the top face of the stack. A second welder welds the folded-over film sections together on the top face of the stack. | 12-25-2014 |
Frank Michels, Speyer DE
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20140156634 | UNIFICATION OF SEARCH AND ANALYTICS - A system includes reception of a request conforming to a modeled query and join filter criteria, the request comprising a first subrequest associated with a search attribute view and a second subrequest associated with an analytical view, definition of a join between the search attribute view and the analytical view based on one or more view attributes of the search attribute view, and filtering of a result set associated with the first subrequest based on the join and on the join filter criteria. | 06-05-2014 |
Frank Michels, Heilberscheid DE
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20140234608 | Colored polymeric molded bodies, and method and device for producing the molded bodies - A method is provided for producing colored molded bodies based on the following steps: (a) plasticising a polymeric material and blending the material with one or more dyes to form a molding compound by means of a gelation unit equipped with a metering apparatus for dyes; (b) optionally temporarily storing the molding compound obtained in step (a); (c) charging a molding device with the molding compound; and (d) producing the molded body; wherein the ratio of dye to polymeric material is automatically regulated using a colorimeter and an electronic control, and in step (a) color values are measured at the molding compound located in the gelation unit and transmitted as a signal to the electronic control. | 08-21-2014 |
Frank-Rolf Michels, Kleve DE
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20100071317 | APPARATUS FOR PULLING FOIL HOOD DOWN OVER LARGE OBJECT - An apparatus for pulling a tubular film down over a large object has at least two guide and roller assemblies each flanking the object and each movable vertically along the object. Each assembly has a guide, an outer roller and an inner roller. The film is gathered by positioning the assemblies in an upper position, orienting the inner rollers generally below the outer rollers, and rotating the rollers while gripping the hood between them to pull the tube down and form it into folds beneath the roller assemblies. The film is pulled down over the object by orienting the inner rollers generally above the outer rollers, and then shifting the roller assemblies downward while rotating the rollers so as to pull the tube up and unfold it. | 03-25-2010 |
20110146209 | METHOD OF AND APPARATUS FOR WRAPPING A STACK OF OBJECTS WITH A FILM - An apparatus for wrapping a stack of objects with a film has first and second supplies of films and a pull-down device shiftable vertically along the stack of objects. A film-feed head has a drive roller rotatable about an axis in the film feed head and first and second pairs of counterrollers angularly offset from each other relative to the drive-roller axis. The drive roller and the pairs of counterrollers are relatively shiftable between end positions in each of which one of the pairs is spaced from the drive roller and the other pair is engaged with the drive roller. The first and second films pass between the respective first and second pairs and the drive roller. An actuator can shift the first and the second pairs of rollers relative the drive roller for pinching the films against the drive roller and, on rotation of the drive roller. | 06-23-2011 |
20110146210 | METHOD OF AND APPARATUS FOR WRAPPING A STACK OF OBJECTS WITH A FILM - An apparatus for wrapping a stack of objects with a film has a film supply holding the film and a support including only two vertical masts adjacent the film supply and juxtaposed with the stack to be wrapped. A pull-down device is shiftable vertically along the two masts next to the stack. A film-feed head is also shiftable vertically along the two masts. The film extends from the supply through the film-feed head to the pull-down device. A film-storing means or looper is provided in the film-feed head for storing a variable length of the film in the head. | 06-23-2011 |
20110185687 | APPARATUS FOR WRAPPING A STACK OF OBJECTS WITH A FILM - An apparatus for wrapping an object with a film has a film-feed head having a drive for pulling the film from a supply and feeding it in a feed direction through the head toward an object to be wrapped with the film and a pull-down device downstream in the direction from the head for drawing the film around the object. A blower directs a stream of air in the feed head parallel and immediately adjacent to the film and in the feed direction so as to entrain the film in the direction. | 08-04-2011 |
20110258970 | METHOD AND APPARATUS FOR WRAPPING A FOIL AROUND A STACK OF OBJECTS - An apparatus for wrapping a film around each of a sequence of objects passing sequentially through a wrapping station has a supply of the film adjacent the station, a feed head at the station having a base, a support carried on the base and rotatable relative thereto about a vertical axis, and a feeder on the base for pulling the film off the supply and feeding it to the support. A film storer carried on the support is operable to take in and store a length of film fed to the support by the feeder. A pull-down device in the station is vertically displaceable below the feed head. | 10-27-2011 |
Georg Michels, Aalen DE
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20150105002 | TOOL FOR THE POLISHING OF OPTICAL SURFACES - A tool for the polishing of an optical surface has a base which has an active surface facing the optical surface. An intermediate layer is arranged on the active surface of the base. A polishing agent carrier is arranged on the elastic intermediate layer. The elastic intermediate layer projects radially beyond the active surface of the base and the polishing agent carrier projects radially beyond the elastic intermediate layer. | 04-16-2015 |
Gisbert Michels, Leverkusen DE
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20130158183 | IMPACT MODIFIED POLYCARBONATE COMPOSITIONS - The invention relates to thermoplastic polycarbonate compositions which are impact-modified with ABS type polymers, said polycarbonate compositions being impact-modified with ABS type polymers are characterized by their excellent low temperature ductility, good processing properties expressed by relatively high melt volume rate (MVR) and good hydrolytic stability. | 06-20-2013 |
Horst Michels, Melsungen DE
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20110053015 | Control Method for a Fuel Cell System and Fuel Cell System - In a method for controlling a fuel cell system that is designed to react a fuel with an oxidant, the fuel cell system can be switched between an idle condition and an active operating condition. In the idle condition, energy is supplied to an energy consumer, at least in part, from an energy storage device, and the fuel is moved actively within the fuel cell system. | 03-03-2011 |
Jan Stefan Michels, Paderborn DE
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20120091818 | SYSTEM FOR SUPPLYING BUS SUBSCRIBER MODULES WITH CONTACTLESS ENERGY AND DATA - A supply system for supplying in a contact-free manner electrical energy and data signals to a subscriber module, including a support member, a supply bar mounted on the support member, which supply bar supports primary energy and data interfaces, and at least one bus subscriber module mounted on the support member, which bus subscriber module includes secondary energy and data interfaces arranged adjacent and spaced from the primary energy and data interfaces, respectively, whereby electrical energy and data signals supplied to the primary interfaces are transmitted in a contact-free manner to the secondary interfaces, respectively. Preferably the support member is a mounting rail having an inverted top-hat configuration, with the supply bar being mounted longitudinally in the space defined by the horizontal bottom and vertical side walls of the mounting rail. | 04-19-2012 |
Juergen Michels, Koln DE
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20120195791 | Method for Deactivating Undesired Contaminations in Leech Extracts - The present invention provides a method for inactivating viruses and/or bacteria in medicinal-leech extracts by means of electromagnetic radiation. | 08-02-2012 |
Jürgen Michels, Dossenheim DE
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20080289523 | Anilox Printing Unit and Printing Press Having an Anilox Printing Unit - An anilox printing unit includes, as inking unit rolls, an ink applicator roll and an engraved roll mounted in rapid change roll sockets, for removing the engraved roll from the roll sockets and inserting another engraved roll into the roll sockets by an operator. The engraved roll is hollow and a temperature control fluid flows therethrough. The engraved roll and the ink applicator roll each have bearer rings. A device which presses the bearer rings of one inking unit roll against the bearer rings of the other inking unit roll has springs for compensating for diameter differences as a result of manufacturing tolerances between the bearer rings of the engraved roll and the bearer rings of the other engraved roll and for compensating for thermally induced diameter changes of the bearer rings of the engraved roll. A printing press having an anilox printing unit is also provided. | 11-27-2008 |
20090078136 | Printing Press with Bearer Rings - A printing press includes a first rotary body with a first bearer ring and a second rotary body with an axle which eccentrically supports a second bearer ring. The second bearer ring is in rolling contact with the first bearer ring and is rotatably coupled to the second rotary body. | 03-26-2009 |
20090193988 | Printing Press Having an Anilox Inking Unit with an Associated Washing Device - A printing press includes an anilox inking unit having an engraved roller and a washing device with a feed device for introducing detergent and a removal device for removing the detergent and printing ink. Further rollers are disposed between the feed device and the engraved roller and between the engraved roller and the removal device, as viewed in a conveying direction of the detergent. An effective length of the further rollers increases from the feed device to the removal device. | 08-06-2009 |
20100083857 | Printing Press - A printing press includes a roller having a first antifriction bearing and a second antifriction bearing. The first antifriction bearing has rolling bodies, a first ring and a second ring. One of the two rings forms an outer ring and the other of the two rings forms an inner ring. Roller sockets are configured as quick action changing devices for receiving the anti-friction bearings during insertion of the roller into the printing press. The first antifriction bearing is configured as an axial floating bearing with a considerable axial movement play of the rolling bodies between the latter and one of the rings. The second antifriction bearing is configured as an axial locating bearing without such a considerable axial movement play. A centering device centers one of the rings relative to the other. | 04-08-2010 |
Jürgen Michels, Ladenburg DE
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20110192305 | INK CONTROL METHOD FOR PRINTING PRESSES HAVING SHORT INKING UNITS - A method for closed-loop or open-loop control of ink feed in lithographic offset printing presses having at least one inking unit, a control unit and an operating element for adjusting the ink feed across a predetermined ink feed control range, includes subdividing the predetermined control range into partial ranges in the control unit. At least one adjustment parameter of the inking unit or the printing press is assigned to each partial range in the control unit. The control unit determines the appropriate partial range as a function of the ink feed selected with the operating element and adjusts the selected ink feed in the inking unit with associated adjustment parameters in the inking unit and/or in the printing press. | 08-11-2011 |
Jürgen Michels, Dossenheim DE
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20100083857 | Printing Press - A printing press includes a roller having a first antifriction bearing and a second antifriction bearing. The first antifriction bearing has rolling bodies, a first ring and a second ring. One of the two rings forms an outer ring and the other of the two rings forms an inner ring. Roller sockets are configured as quick action changing devices for receiving the anti-friction bearings during insertion of the roller into the printing press. The first antifriction bearing is configured as an axial floating bearing with a considerable axial movement play of the rolling bodies between the latter and one of the rings. The second antifriction bearing is configured as an axial locating bearing without such a considerable axial movement play. A centering device centers one of the rings relative to the other. | 04-08-2010 |
Karsten Michels, Magdeburg DE
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20100132355 | Internal Combustion Engine - An internal combustion engine, in particular an Otto-cycle engine, has an exhaust gas turbocharger and a mechanical charger, wherein a compressor of the exhaust gas turbo charger is disposed upstream of the mechanical charger in the air channel for combustion air such that the compressor of the exhaust gas turbocharger draws combustion air directly from an air filter. A first charge air cooler is disposed downstream of the compressor of the exhaust gas turbocharger and upstream of the mechanical charger. A second charge air cooler is disposed downstream of the mechanical charger. The first charge air cooler, the second charge air cooler, the mechanical charger, and an intake manifold are all arranged in a single charge air cooling module, wherein direct fuel injection into the combustion chambers of the internal combustion engine is provided for supplying fuel. | 06-03-2010 |
Karsten Michels, Dreieich DE
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20140025240 | KINETIC ENERGY CONSUMER MODE CONTROL - A system for providing a set point increase for a vehicle combustion engine includes a control that is operable to control vehicle secondary systems to control the power consumption of the vehicle secondary systems to increase a mechanical load to the vehicle combustion engine. The load increase of the combustion engine may be for increasing the lost heat, which enhances the filtering of exhaust gases of the vehicle combustion engine. The lost heat may be utilized to increase the heat of a carbon particle filter, through which exhaust gases flow. | 01-23-2014 |
Manfred Michels, Koln DE
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20140138922 | Axle Suspension and Axle Lift for a Vehicle Axle - An axle suspension for a vehicle axle guided by a trailing arm and also, furthermore, an axle lift for a vehicle axle are proposed. The axle lift includes a force element ( | 05-22-2014 |
20150115565 | Axle fixation for a sprung vehicle axle - The invention relates to an axle fixation, an axle plate ( | 04-30-2015 |
Markus Michels, Stuttgart DE
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20140217817 | CONTROL DEVICE FOR A DC-TO-DC CONVERTER OF AN ELECTRICAL DRIVE SYSTEM, AND A METHOD FOR OPERATING A DC-TO-DC CONVERTER - The invention relates to an electrical drive system of a hybrid vehicle, comprising: a traction battery ( | 08-07-2014 |
Markus Michels, Langenau DE
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20110233096 | CONTAINER ARRANGEMENT - The invention relates to a container assembly with a box- or bowl-shaped container bottom part ( | 09-29-2011 |
Martin Michels, Koln DE
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20110083984 | Substituted 2,3-dihydroimidazo[1,2-c]quinazoline Derivatives Useful for Treating Hyper-Proliferative Disorders and Diseases Associated with Angiogenesis - This invention relates to novel 2,3-dihydroimidazo[1,2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients. | 04-14-2011 |
20110207731 | SUBSTITUTED 4-(INDAZOLYL)-1,4-DIHYDROPYRIDINES AND METHODS OF USE THEREOF - This invention relates to novel 4-(indazolyl)-1,4-dihydropyridine og the following formula (I) derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly cancer and other proliferative disorders. | 08-25-2011 |
20120035409 | BI- AND TRICYCLIC INDAZOLE-SUBSTITUTED 1,4-DIHYDROPYRIDINE DERIVATIVES AND USES THEREOF - This invention relates to novel bi- and tricyclic indazole-substituted 1,4-dihydropyridine derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly cancer and other proliferative disorders. | 02-09-2012 |
20120190709 | Indazolyl-substituted dihydroisoxa-zolopyridines and methods of use thereof - This invention relates to novel 4-(indazol-5-yl)-4,7-dihydroisoxazolo[5,4-b]pyridine derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly cancer and other proliferative disorders. | 07-26-2012 |
20120264785 | Fluoro-substituted 3,5-dicyano-4-(1H-indazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine derivatives and methods of use thereof - The present invention relates to novel fluoro-substituted 3,5-dicyano-4-(1H-indazol-5-yl)-2,6-dimethyl-1,4-dihy-dropyridine derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly cancer and other proliferative disorders. | 10-18-2012 |
20120270905 | FLUORINATED 2,6-DIALKYL-3,5-DICYANO-4-(1H-INDAZOL-5-YL)-1,4-DIHYDROPYRIDINES AND METHODS OF USE THEREOF - The present invention relates to novel fluorinated 2,6-dialkyl-3,5-dicyano-4-(1H-indazol-5-yl)-1,4-dihydropyridine derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly cancer and other proliferative disorders. | 10-25-2012 |
20130005773 | FLUORO-SUBSTITUTED 2-ARYL-3,5-DICYANO-4-INDAZOLYL-6-METHYL-1,4-DIHYDROPYRIDINES AND USES THEREOF - The present invention relates to novel, fluoro-substituted 2-aryl-3,5-dicyano-4-(1H-indazol-5-yl)-6-methyl-1,4-dihydropyridine derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly Cancer and other proliferative disorders. | 01-03-2013 |
20130131055 | FUROPYRIDINYL-SUBSTITUTED 1,4-DIHYDROPYRIDINE DERIVATIVES AND METHODS OF USE THEREOF - This invention relates to novel 4-(furo[3,2-c]pyridin-2-yl)-1,4-dihydropyridine derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly cancer and other proliferative disorders. | 05-23-2013 |
20130261113 | SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS - This invention relates to novel 2,3-dihydroimidazo[1,2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients. | 10-03-2013 |
Martin Michels, Cologne DE
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20100179125 | SUBSTITUTED 4-AMINO-PYRROLOTRIAZINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS - This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients. | 07-15-2010 |
Martin Michels, Koeln DE
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20080275018 | ANTIBACTERIAL AMIDE-MACROCYCLES V - The invention relates to antibacterial amide-macrocycles of formula (I), in which R | 11-06-2008 |
20080300231 | Antibacterial amide macrocycles VI - The invention relates to antibacterial amide macrocycles and methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, in particular of bacterial infections. | 12-04-2008 |
20080306040 | Antibacterial amide macrocycles VII - The invention relates to antibacterial amide macrocycles and methods for their preparation, their use for the treatment and/or prophylaxis of diseases as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially bacterial infections. | 12-11-2008 |
20110172221 | ANNELLATED 4-(INDAZOLYL)-1,4-DIHYDROPYRIDINE DERIVATIVES AND METHODS OF USE THEREOF - This invention relates to novel annellated 4-(indazolyl)-1,4-dihydropyridine derivatives having protein tyrosine kinase inhibitory activity, to a process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions, particularly cancer and other proliferative disorders. | 07-14-2011 |
Mathias Michels, Lennestadt DE
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20110289761 | Force-Transmitting Element, Sliding Sleeve, Arrangement and Method for Producing a Non-Detachable Workpiece Connection - A force-transmitting element for non-detachable workpiece connections includes a flange portion and a transmitting portion, wherein the transmitting portion has a substantially cylindrical inner peripheral surface and wherein the wall thickness of the transmitting portion tapers at least in sections from the end close to the flange portion to the end remote from the flange portion. An operationally reliable non-detachable workpiece connection can be obtained despite relatively small dimensions of the force-transmitting element. The end of the transmitting portion which is close to the flange portion has at least one latching depression on the outer peripheral surface. | 12-01-2011 |
Paul Michels, Arzbach DE
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20150024137 | Method for the application of an aqueous treatment solution on the surface of a moved steel strip - An apparatus and method for the application of an aqueous treatment solution onto the surface of a steel strip that is moved, at a prespecified strip speed, in a direction of movement of the strip, with the following steps: drying of the moving steel strip with a gas flow; application of the aqueous solution on at least one surface of the steel strip with a rotary sprayer with several spray rotors that are situated next to one another, transverse to the direction of movement of the strip, to which the aqueous treatment solution is supplied and which are rotated by a drive, so as to spray the treatment solution, as a result of centrifugal force, in the form of a spray jet, onto the surface of the steel strip and, there, to form a wet film of the aqueous treatment solution; equalization of the applied wet film of the aqueous treatment solution by driven smoothing rollers; and drying of the applied wet film of the aqueous treatment solution. | 01-22-2015 |
Ralf Michels, Leverkusen DE
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20150276116 | SEALING DEVICE - The invention relates to a sealing device for cylindrical or conical orifices, which is composed of an elongate sealing body made from elastically deformable material, the following components being provided for the deformation of the sealing body: a tension bolt extending through the middle, free passage region of the sealing body, a pressure sleeve seated at the inner end of the tension bolt, a brace which is arranged at the outer end of the tension bolt and through which the tension bolt engages, and an actuation element which acts upon the outer end, projecting through the brace, of the tension bolt and which, when a tensile force is exerted upon the tension bolt, enlarges the sealing body and at the same time its outer circumference. | 10-01-2015 |
Robert Michels, Thierhaupten DE
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20080209852 | Joining Assembly and Method for Joining Components - A joining assembly includes metallic, ceramic, polymeric and/or fiber-reinforced components, which have at least one joining surface with at least one recess and/or raised area with an undercut. The joining assembly also includes a joining element that conforms in size and shape to the recess and/or the raised area of the components to be joined and has at least one flexible rim area. The flexible rim area can be placed in a form-locking and force-locking interconnection with the recesses and/or raised areas of the components to be joined. A method for joining components is also provided. | 09-04-2008 |
20090302552 | Sealing Material - A sealing material is formed as a planar laminate compound made of at least two layers of a graphite film with a maximum density of 1.6 g/cm | 12-10-2009 |
20130032750 | GRAPHITE-CONTAINING PLATE AND METHOD FOR PRODUCING A GRAPHITE-CONTAINING PLATE - A graphite-containing plate contains a solidified mixture of substantially evenly distributed graphite particles and plastic particles. In the method, graphite particles and plastics particles are mixed to form a mixture of substantially uniform distribution. The mixture is subsequently solidified. | 02-07-2013 |
20130168040 | CEILING OR WALL ELEMENT WITH A HEATING OR COOLING REGISTER - A ceiling or wall element for fixing to a ceiling or a wall is provided with a frame that has a base plate which can be fixed to the ceiling and/or to the wall. A heating or cooling register is arranged in or on the frame. A non-woven fabric and a perforated graphite film are disposed between the base plate of the frame and the heating or cooling register. | 07-04-2013 |
20130192793 | DEVICE FOR TEMPERATURE CONTROL OF A ROOM - A device for tempering a room includes at least one component that forms a thermal accumulator and has a surface oriented towards the room. Tubes that are thermally coupled to the component can be traversed by a heating or cooling medium. The tubes are integrated into a panel that contains expanded graphite or is made of expanded graphite. The panel is in areal thermal contact with the surface of the component that faces towards the room. | 08-01-2013 |
Thomas Michels, Dortmund Germany DE
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20140338074 | MICROSCOPE PROBE AND METHOD FOR USE OF SAME - A microscope probe includes a substrate; an optical resonator disposed on the substrate and including an optical resonance property; a displacement member disposed on the substrate and separated from the optical resonator, the displacement member including: a first end disposed distal to the optical resonator; and a second end disposed proximate to the optical resonator; and a coupling member disposed on the substrate and connecting the displacement member to the substrate, wherein the first end is configured to probe a sample and to be displaced in response to a condition of the sample, the displacement member is configured to communicate displacement of the first end to the second end, and the second end is configured to change the optical resonance property in response to displacement of the second end | 11-13-2014 |
Thorsten Michels, Gross-Gerau DE
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20110086432 | DEVICE FOR MIXING A LIQUID SAMPLE - A device and a process for mixing a liquid sample in an automated analysis instrument comprises a support arm, a holder for a liquid container, a flexible intermediate element, arranged between the support arm and the holder for the liquid container, a shaking apparatus, and a coupling apparatus arranged on the holder for the liquid container, wherein the coupling apparatus can establish a detachable connection between the shaking apparatus and the holder for the liquid container. | 04-14-2011 |
20120072027 | METHOD AND APPARATUS FOR LOW-VOLUME ANALYZER WITH FIXED AND VARIABLE INDEXING - A sample analyzer with fixed and variable indexing that is structured and arranged to align reaction vessels, e.g., cuvettes, at a pre-determined, fixed point while maintaining a positional sequence using variable indexing. Variable indexing allows cuvettes to be presented to multiple, fixed point resources at multiple occasions in a systematic progression in a highly efficient manner. The presentation of cuvettes to multiple, fixed point resources at multiple times is superior to existing indexing. | 03-22-2012 |
20130195718 | Method for Heating a Volume of Liquid in a Heated Pipetting Needle - The invention relates to a pipetting device for automatic analysis instruments and a method for heating a volume of liquid in a heated pipetting needle. | 08-01-2013 |