Michael Nicholas
Michael Nicholas Guerini, Gilroy, CA US
Patent application number | Description | Published |
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20140335566 | MOBILE VESSEL OR CARRIER FOR THE MANUFACTURING PRODUCTION AND PURIFICATION OF BIOLOGICS - Embodiments described herein relate to mobile biologics production systems that can be transported to a site where a production of biologics is required, and is operable to produce the biologics on-site on demand. A mobile biologics production system can include a mobile carrier configured to be trailered to a biologics production location. The mobile carrier defines an interior volume configured to provide an aseptic environment for manufacturing, production, and purification of biologics. A production sub-system disposed in the interior volume includes a single-use bioreactor configured to grow biologics which can include microbes, mammalian cell lines, insect cell lines, and plant cell lines. The bioreactor is controlled by a controller, and can have a working capacity of less than about 100 L. A purification sub-system disposed in the internal volume is fluidically coupled to the production sub-system and configured to produce a finished biologic product. | 11-13-2014 |
Michael Nicholas Mandikos, Queensland AU
Patent application number | Description | Published |
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20120219924 | ILLUMINATING DENTAL INSTRUMENT, COUPLING AND METHOD OF USE - A dental instrument, or a coupling connectable to the dental instrument, comprises an illuminator having a plurality of light emitting diodes that are each capable of emitting light at a selected wavelength in a range 260 to 880 nm. White or near white light emitting diodes may also be included together with a switch. Fluorescence-based diagnosis can be assisted by the use of a single dye or mixture of dyes. Light of about 400-540 nm wavelength may be used to distinguish composite, porcelain or other tooth coloured filling materials from normal tooth structures. Light of about 260-450 nm wavelength may be used to identify dental caries, calculus and/or dental plaque. Light of about 350-500 nm wavelength may be used to cure dental composite. Typically, the dental instrument is, or comprises, a drill, de-scaler, or other instruments such as for cleaning, examination or diagnosis of dental conditions. | 08-30-2012 |
Michael Nicholas Mantzouris, Scarsdale, NY US
Patent application number | Description | Published |
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20130066653 | Apparatus and method for linking a pacemaker or a defibrillator to an electronic healthcare record - A computer-implemented method, including accessing, with a communication device, a computer in which is stored a healthcare record, or a medical record, of, for, or regarding, an individual or a patient, accessing, with the communication device, the healthcare record or the medical record of, for, or regarding, the individual or the patient, accessing or linking to a pacemaker, a pacemaker monitor, a defibrillator, or a defibrillator monitor, of or associated with the individual or the patient, with or using the communication device, and performing, via, with, or using, the communication device, a control, a monitoring, a diagnostic, a programming, a re-programming, a repair, a calibration, a setting, or a re-setting, action, operation, or function, on, regarding, or relating to, the pacemaker, the pacemaker monitor, the defibrillator, or the defibrillator monitor. | 03-14-2013 |
Michael Nicholas Pitsakis, Coral, PA US
Patent application number | Description | Published |
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20080312723 | Apparatus and Method for Inducing Suspended Animation Using Rapid, Whole Body, Profound Hypothermia - Disclosed is a transportable apparatus that maintains a large volume of a cold solution at a preset low temperature and rapidly delivers it to an irresuscitable patient's thoracic aorta at a preset and controlled flow rate, while monitoring pressure and eliminating the introduction of air embolisms into the patient, for the purpose of inducing profound hypothermia and suspended animation until proper treatment of the patient is available. The induction of suspended animation is intended for preservation of viability of the brain, heart, and organs for subsequent repair and resuscitation or for organ harvesting. The procedure may be performed by emergency personnel on the scene of an accident and/or while the patient is being transported in an emergency vehicle, or while in a hospital. | 12-18-2008 |