Patent application number | Description | Published |
20100261613 | METHODS FOR INFLAMMATORY DISEASE MANAGEMENT - Quantitative expression datasets are created and used in the identification, monitoring and treatment of disease states and characterization of biological conditions. Quantitative datasets are derived from subject samples and enable evaluation of a biological condition. Such quantitative datasets may be used to provide an output score indicative of the biological state of a subject through analysis against a profile dataset. | 10-14-2010 |
20110137851 | BIOMARKERS AND METHODS FOR MEASURING AND MONITORING INFLAMMATORY DISEASE ACTIVITY - Biomarkers useful for diagnosing and assessing inflammatory disease are provided, along with kits for measuring their expression. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples. The biomarkers include at least two biomarkers selected from the DAIMRK group and the score is a disease activity index (DAI). | 06-09-2011 |
20120116685 | Methods, System, And Medium For Associating Rheumatoid Arthritis Subjects With Cardiovascular Disease - The present invention relates to a system and a medium for analyzing one or more analytes in rheumatoid arthritis subjects to determine whether the subject is at increased risk of diseases such as a cardiovascular disease, the subject's current cardiovascular disease burden, and the likelihood of cardiovascular disease progression in the subject. In addition, the present invention further provides methods for analyzing data to determine risk of cardiovascular disease, current cardiovascular disease burden, and the likelihood of cardiovascular disease progression in a rheumatoid arthritis subject. | 05-10-2012 |
20130073213 | Gene Expression-Based Differential Diagnostic Model for Rheumatoid Arthritis - Biomarkers useful for differential diagnosis for rheumatoid arthritis from samples of peripheral blood mononuclear cells are provided, along with kits for measuring their expression. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples. | 03-21-2013 |
20130149398 | COMPOSITIONS OF HERBAL FORMULATIONS AND USES THEREOF - Disclosed herein are herbal formulations for relief from symptoms of skin disease. The formulations can also be combined with an active or inactive pharmaceutical ingredient, and/or a pharmaceutically acceptable excipient. | 06-13-2013 |
20140128276 | CYTOKINE PROFILES AS METHODS FOR DIAGNOSIS AND PROGNOSIS OF IRRITABLE BOWEL SYNDROME - Methods, devices, and kits for diagnosing or evaluating irritable bowel syndrome employ an analysis for the presence and amount of specific cytokines. The levels of such cytokines provide an index for diagnosis and/or evaluation of therapeutic response. Samples to be tested include peripheral blood, serum, plasma, or tissue from a human subject having or suspected of having Irritable Bowel Syndrome. | 05-08-2014 |
20140142861 | Biomarkers For Predicting Progressive Joint Damage - A method scores a sample, by receiving a first dataset associated with a first sample obtained from a first subject, wherein said first dataset comprises quantitative data for at least two markers selected from the group consisting of: CCL22; CHI3L1; COMP; CRP; CSF1; CXCL10; EGF; ICAM1; ICAM3; ICTP; IL1B; IL2RA; IL6; IL6R; IL8; LEP; MMP1; MMP3; PYD; RETN; SAA1; THBD; TIMP1; TNFRSF11B; TNFRSF1A; TNFSF11; VCAM1; and VEGFA; and determining a first SDI score from said first dataset using an interpretation function, wherein the first SDI score provides a quantitative measure of the rate of change in joint structural damage in said first subject. | 05-22-2014 |
20140200826 | Methods For Inflammatory Disease Management - Quantitative datasets are created and used in the identification, monitoring and treatment of disease states and characterization of biological conditions. | 07-17-2014 |
20140303902 | Methods, System, and Medium for Associating Rheumatoid Arthritis Subjects with Cardiovascular Disease - The present invention relates to a system and a medium for analyzing one or more analytes in rheumatoid arthritis subjects to determine whether the subject is at increased risk of diseases such as a cardiovascular disease, the subject's current cardiovascular disease burden, and the likelihood of cardiovascular disease progression in the subject. In addition, the present invention further provides methods for analyzing data to determine risk of cardiovascular disease, current cardiovascular disease burden, and the likelihood of cardiovascular disease progression in a rheumatoid arthritis subject. | 10-09-2014 |