Patent application number | Description | Published |
20150230713 | Devices, Systems, and Methods and Associated Display Screens for Assessment of Vessels - Devices, systems, and methods for visually depicting a vessel and evaluating treatment options are disclosed. The methods can include obtaining pressure measurements from first and second instruments positioned within a vessel of a patient while the second instrument is moved longitudinally through the vessel from a first position to a second position and the first instrument remains stationary within the vessel; and outputting a visual representation of the pressure measurements obtained by the first and second instruments on a display, the output visual representation including a graphical display of a pressure ratio of the obtained pressure measurements and at least a portion of a pressure waveform of the obtained pressure measurements identifying a diagnostic period utilized in calculating the pressure ratio. | 08-20-2015 |
20150238096 | Devices, Systems, and Methods and Associated Display Screens for Assessment of Vessels - Devices, systems, and methods for visually depicting a vessel and evaluating treatment options are disclosed. The methods can include obtaining pressure measurements from first and second instruments positioned within a vessel of a patient while the second instrument is moved longitudinally through the vessel from a first position to a second position and the first instrument remains stationary within the vessel; and outputting a visual representation of the pressure measurements obtained by the first and second instruments on a display, the output visual representation including a graphical display of a pressure ratio of the obtained pressure measurements and at least a portion of a pressure waveform of the obtained pressure measurements identifying a diagnostic period utilized in calculating the pressure ratio. | 08-27-2015 |
20160073972 | BEDSIDE CONTROLLER FOR ASSESSMENT OF VESSELS AND ASSOCIATED DEVICES, SYSTEMS, AND METHODS - Devices, systems, and methods for evaluating a vessel of a patient are provided. The method includes outputting, to a touch-sensitive display of a bedside controller, a screen display including: a visual representation of a first pressure ratio of pressure measurements obtained by first and second instruments positioned within a vessel while the second instrument is moved from a distal position to a proximal position relative a stenosis and the first instrument remains stationary; and a first proximal pressure waveform and a first distal pressure waveform; receiving, through the touch-sensitive display of the bedside controller, a user touch input on the first proximal pressure waveform and/or the first distal pressure waveform identifying a time at which pressure measurements were obtained; and modifying the screen display, in response to the user touch input, to further include a visual representation of the obtained pressure measurements corresponding to the identified time. | 03-17-2016 |
Patent application number | Description | Published |
20130120296 | Medical Mounting System and Method - A bedside controller includes an integrally formed housing and self-contained mounting structure disposed on the housing. The mounting structure includes a mounting channel defined in the housing and a retaining clamp disposed above the mounting channel and configured to releasably secure a mounting platform within the mounting channel such that the bedside controller is mounted to the mounting platform. The bedside controller also includes a touch-sensitive display disposed within a surface of the housing and configured to display images and receive user input on the surface, a processor disposed within the housing, a communication module disposed within the housing, communicatively coupled to the processor, and configured to transmit and receive medical data, and a battery disposed within the integrally formed housing and electrically coupled to the touch-sensitive display, the processor, and the communication module. | 05-16-2013 |
20130120297 | Medical Measuring System and Method - A method of performing measurements on medical images with a bedside controller includes receiving, through a touch-sensitive display on the bedside controller, a user measurement input on an image displayed on the display, the user measurement input including a start point defined by a point of initial contact with the touch-sensitive display and an end point defined by a point of last contact with the touch-sensitive display. The method also includes selecting a measurement mode based on a shape of the user measurement input and calculating a measurement value associated with the user measurement input based on the measurement mode. | 05-16-2013 |
20130123616 | Medical Workflow System and Method - A method of conducting a medical workflow with a touch-sensitive bedside controller is disclosed. The method includes initiating a medical workflow using a graphical user interface on the bedside controller, positioning an imaging tool within a patient's body based on images captured by the imaging tools and displayed on the bedside controller, controlling the commencement and termination of a recordation of images captured by the imaging tool using the graphical user interface on the bedside controller, navigating through the recorded images to identify an image of interest using the graphical user interface on the bedside controller, and performing measurements on the image of interest using the graphical user interface on the bedside controller. | 05-16-2013 |
20140100440 | SYSTEM AND METHOD FOR INSTANT AND AUTOMATIC BORDER DETECTION - The invention generally relates to medical imaging systems that instantly and/or automatically detect borders. Embodiments of the invention provide an imaging system that automatically detects a border at a location within a vessel in response only to navigational input moving the image to that location. In some embodiments, systems and methods of the invention operate such that when a doctor moves an imaging catheter to a new location with in tissue, the system essentially instantly finds, and optionally displays, the border(s), calculates an occlusion, or both. | 04-10-2014 |
20140181716 | Gesture-Based Interface for a Multi-Modality Medical Imaging System - Systems and methods for multi-modality data processing are provided. Some embodiments are particularly directed to interpreting gesture-based commands in a multi-modality processing system. In one embodiment, a method for interpreting user input in a medical processing system includes receiving a state designator corresponding to a mode of operation of the medical processing system, where the mode of operation includes a value representative of a modality selected from the group consisting of: IVUS, OCT, pressure, and flow. A list of active commands is generated based on the received state designator. A user input sequence is received from one or more user input devices. The medical processing system correlates the user input sequence to a command of the list of active commands, and the command is utilized to control operation of a component of the system. The list of active command may include a subset of commands common to multiple modalities. | 06-26-2014 |
20150112152 | Devices, Systems, and Methods for Assessing a Vessel With Optimized Proximal and Distal Pressure Measurements Obtained Without the Use of a Hyperemic Agent - Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to assess the severity of a stenosis in the coronary arteries without the administration of a hyperemic agent. In some embodiments, the devices, systems, and methods of the present disclosure are configured to optimize proximal and distal pressure measurements utilized to assess the vessel. | 04-23-2015 |
20150119705 | Devices, Systems, and Methods for Vessel Assessment - Devices, systems, and methods for visually depicting a vessel and evaluating risk associated with a condition of the vessel are disclosed. In one embodiment, a method of evaluating a vessel of a patient includes obtaining physiology measurements from a first instrument and a second instrument positioned within the vessel of the patient while the second instrument is moved longitudinally through the vessel from a first position to a second position and the first instrument remains stationary within the vessel; outputting the physiology measurements and an image of the vessel on a display, the output image including visualizations based on the obtained physiology measurements; and evaluating whether to perform to surgical procedure based on the physiology measurements and the image of the vessel. | 04-30-2015 |
Patent application number | Description | Published |
20100048547 | PI 3-KINASE INHIBITORS AND METHODS OF THEIR USE - Phosphatidylinositol (PI) 3-kinase inhibitor compounds, their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases, including proliferative diseases, inflammatory and obstructive airways diseases, allergic conditions, autoimmune and cardiovascular diseases. | 02-25-2010 |
20100075965 | PI3 KINASE INHIBITORS AND METHODS OF THEIR USE - Phosphatidylinositol (PI) 3 kinase inhibitor compounds, their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, phospholipid kinases, G-protein coupled receptors, and phosphatases. | 03-25-2010 |
20120225859 | PYRIMIDINE DERIVATIVES USED AS PI-3 KINASE INHIBITORS - Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases. | 09-06-2012 |
Patent application number | Description | Published |
20090018439 | Marker delivery divice with releasable plug - The invention is directed to marker delivery devices and methods of using such devices. The delivery devices embodying features of the invention include a delivery cannula with a discharge opening and a releasable plug disposed in the inner lumen of the delivery cannula so as to at least partially occlude the discharge opening. The releasable plug prevents ingress of tissue, body fluids and the like into the bore of the tube, and prevents the premature discharge of any markers proximal to the releasable plug from passing through the discharge opening before the distal end of the cannula is properly positioned at a desired location within a patient's body. The releasable plug preferably has an MRI detectable element. Preferably, at least one remotely detectable marker mass is provided in the inner lumen of the cannula proximal to the releasable plug. | 01-15-2009 |
20090171198 | Powdered marker - The marker delivery system described has a delivery tube or cannula which has a bioabsorbable powdered mass and a radiographically detectable element within an inner lumen thereof. The powdered material is a starch such as USP (corn) starch or other suitable polysaccharide. The radiographically detectable element may be disposed within or coupled to a bioabsorbable pellet. | 07-02-2009 |
20100094169 | Plugged tip delivery tube for marker placement - The invention provides marker delivery devices, assemblies, and methods. Assemblies embodying features of the invention include marker delivery devices having a delivery tube with an orifice, markers, and a plug releasably disposed in the tube occluding the orifice. The plug prevents markers from passing through the orifice before the marker is to be placed at a desired location within a patient's body, prevents ingress of tissue into the bore of the tube, and allows markers to pass out of the orifice when marker delivery is desired. Guidance of a delivery tube to a desired location within a patient's body may include the use of an imaging device, with or without the use of a guide cannula. The plug may itself serve as a marker, and may be the sole marker. Markers may be detectable by ultrasound, X-ray, magnetic resonance imaging, and other imaging devices, and may include bioactive elements. | 04-15-2010 |
20110166448 | MARKER DELIVERY DEVICE WITH RELEASABLE PLUG - A marker delivery device includes an elongated delivery cannula which has a distal end section, an inner lumen and a discharge opening in the distal end section in communication with the inner lumen. At least one elongated fibrous marker body is slidably disposed within the inner lumen of the elongated delivery cannula. The at least one elongated fibrous marker body includes a plurality of bioabsorbable polymeric strands. The strands are compressed to a compressed configuration and bound together in the compressed configuration with a polymer binding agent prior to insertion into the elongated delivery cannula. A releasable plug is disposed within a distal portion of the inner lumen and distal to the at least one elongated fibrous marker body so as to at least partially occlude the discharge opening in the distal end section. | 07-07-2011 |
20110184280 | INTRACORPOREAL MARKER AND MARKER DELIVERY DEVICE - An elongated intracorporeal remotely detectable marker includes a core of bioabsorbable fibers. An outer jacket of bioabsorbable fibers is disposed around at least part of the core. In one embodiment, for example, the core has a longitudinal extent and a pair of opposed ends, and the outer jacket is disposed around the longitudinal extent of the core, with the pair of opposed ends being exposed. | 07-28-2011 |
20120215230 | PLUGGED TIP DELIVERY TUBE FOR MARKER PLACEMENT - An intracorporeal marker delivery device includes a delivery tube which has a distal tip, a discharge orifice and an inner bore extending to the discharge orifice. A plug is releasably secured within the inner bore. The plug may itself serve as a marker, and may be the sole marker. Markers may be positioned proximal to the plug, and may be detectable by ultrasound, X-ray, magnetic resonance imaging, and other imaging devices, and may include bioactive elements. | 08-23-2012 |
20130144157 | MARKER DELIVERY DEVICE WITH RELEASABLE PLUG - A marker delivery device includes an elongated delivery cannula which has a distal end section, an inner lumen and a discharge opening in the distal end section in communication with the inner lumen. At least one elongated fibrous marker body is slidably disposed within the inner lumen of the elongated delivery cannula. The at least one elongated fibrous marker body includes a plurality of bioabsorbable polymeric strands. The strands are compressed to a compressed configuration and bound together in the compressed configuration with a polymer binding agent prior to insertion into the elongated delivery cannula. | 06-06-2013 |
20130281847 | INTRACORPOREAL MARKER AND MARKER DELIVERY DEVICE - An intracorporeal marker system includes a tissue marker pellet comprised of a polysaccharide material. The intracorporeal marker system may also include a fibrous marker of bioabsorbable fibers. In one embodiment, for example, an outer layer of bioabsorbable fibers is disposed around at least part of an inner core of bioabsorbable fibers. | 10-24-2013 |
20150141805 | MARKER DELIVERY DEVICE WITH RELEASABLE PLUG - A marker delivery device includes an elongated delivery cannula which has a distal end section, an inner lumen and a discharge opening in the distal end section in communication with the inner lumen. A plunger is slidably disposed within the inner lumen of the elongated delivery cannula. The plunger has a distal end. At least one elongated fibrous marker body is pre-formed prior to being inserted into the inner lumen of the elongated delivery cannula. The at least one elongated fibrous marker body is slidably disposed within the inner lumen of the elongated delivery cannula at a location distal to the distal end of the plunger. The pre-formed at least one elongated fibrous marker body includes a fibrous material compressed and impregnated with a binding agent and freeze dried in the compressed condition. A releasable plug is disposed within a distal portion of the inner lumen and distal to the at least one elongated fibrous marker body. | 05-21-2015 |
Patent application number | Description | Published |
20140287711 | EMERGENCY MOBILE NOTIFICATION HANDLING - Systems and methods for handling emergency notification messages such as Commercial Mobile Alert System (CMAS) alerts. In one example, a mobile communications device receives a text-based emergency alert message, converts at least some of the message content into an audio format, and then audibly plays the message. Such a system may enable additional persons to receive emergency notifications who otherwise may not receive them, for example, persons with visual impairments, or persons using communications devices that are unable to display text. In another example arrangement, a response center receives a text-based message, recognizes that a particular remote communications device is not capable of displaying the text-based message, derives from the content of the text-based electronic notification message data or signals that render at least some of the content of the text-based electronic notification message into an audio format, and transmits the data or signals to the communications device. | 09-25-2014 |
20150110255 | EMERGENCY MOBILE NOTIFICATION HANDLING - Systems and methods for handling emergency notification messages such as Commercial Mobile Alert System (CMAS) alerts. In an example scenario, a call center maintains personal profiles of a number of clients, including contact information for persons or other entities designated by the clients to receive information about the clients. The call center receives from a device associated with a particular client of the call center that the client's device has received a text-based emergency notification message. The call center notifies one or more of the designated entities. The notification may include the content of the emergency notification message, and may include an audio version of the notification message. An indication or the notification message may also be placed in a database accessible to one or more of the designated persons or entities. | 04-23-2015 |
Patent application number | Description | Published |
20110048575 | VISCOUS MATERIAL NONCONTACT JETTING SYSTEM - A viscous material noncontact jetting system has a jetting dispenser mounted for relative motion with respect to a surface. A control is operable to cause the jetting dispenser to jet a viscous material droplet that is applied to the surface as a viscous material dot. A device, such as a camera or weigh scale, is connected to the control and provides a feedback signal representing a size-related physical characteristic of the dot applied to the surface. The size-related physical characteristics of subsequently applied dots is controlled by heating and cooling, or adjusting a piston stroke in the jetting dispenser, in response to the size-related physical characteristic feedback. Dispensed material volume control and velocity offset compensation are also provided. | 03-03-2011 |
20110184569 | VISCOUS MATERIAL NONCONTACT JETTING SYSTEM - A viscous material noncontact jetting system has a jetting dispenser mounted for relative motion with respect to a surface. A control is operable to cause the jetting dispenser to jet a viscous material droplet that is applied to the surface as a viscous material dot. A device, such as a camera or weigh scale, is connected to the control and provides a feedback signal representing a size-related physical characteristic of the dot applied to the surface. The size-related physical characteristics of subsequently applied dots is controlled by heating and cooling, or adjusting a piston stroke in the jetting dispenser, in response to the size-related physical characteristic feedback. Dispensed material volume control and velocity offset compensation are also provided. | 07-28-2011 |
20120285990 | Viscous Material Noncontact Jetting System - A viscous material noncontact jetting system has a jetting dispenser mounted for relative motion with respect to a surface. A control is operable to cause the jetting dispenser to jet a viscous material droplet that is applied to the surface as a viscous material dot. A device, such as a camera or weigh scale, is connected to the control and provides a feedback signal representing a size-related physical characteristic of the dot applied to the surface. The size-related physical characteristics of subsequently applied dots is controlled by heating and cooling, or adjusting a piston stroke in the jetting dispenser, in response to the size-related physical characteristic feedback. Dispensed material volume control and velocity offset compensation are also provided. | 11-15-2012 |
Patent application number | Description | Published |
20080207997 | METHOD AND APPARATUS FOR CONTINUOUS GUIDANCE OF ENDOSCOPY - Methods and apparatus provide continuous guidance of endoscopy during a live procedure. A data-set based on 3D image data is pre-computed including reference information representative of a predefined route through a body organ to a final destination. A plurality of live real endoscopic (RE) images are displayed as an operator maneuvers an endoscope within the body organ. A registration and tracking algorithm registers the data-set to one or more of the RE images and continuously maintains the registration as the endoscope is locally maneuvered. Additional information related to the final destination is then presented enabling the endoscope operator to decide on a final maneuver for the procedure. The reference information may include 3D organ surfaces, 3D routes through an organ system, or 3D regions of interest (ROIs), as well as a virtual endoscopic (VE) image generated from the precomputed data-set. The preferred method includes the step of superimposing one or both of the 3D routes and ROIs on one or both of the RE and VE images. The 3D organ surfaces and routes may correspond to the surfaces and paths of a tracheobronchial airway tree extracted, for example, from 3D MDCT images of the chest. | 08-28-2008 |
20100280365 | GUIDANCE METHOD BASED ON 3D-2D POSE ESTIMATION AND 3D-CT REGISTRATION WITH APPLICATION TO LIVE BRONCHOSCOPY - A method provides guidance to the physician during a live bronchoscopy or other endoscopic procedures. The 3D motion of the bronchoscope is estimated using a fast coarse tracking step followed by a fine registration step. The tracking is based on finding a set of corresponding feature points across a plurality of consecutive bronchoscopic video frames, then estimating for the new pose of the bronchoscope. In the preferred embodiment the pose estimation is based on linearization of the rotation matrix. By giving a set of corresponding points across the current bronchoscopic video image, and the CT-based virtual image as an input, the same method can also be used for manual registration. The fine registration step is preferably a gradient-based Gauss-Newton method that maximizes the correlation between the bronchoscopic video image and the CT-based virtual image. The continuous guidance is provided by estimating the 3D motion of the bronchoscope in a loop. Since depth-map information is available, tracking can be done by solving a 3D-2D pose estimation problem. A 3D-2D pose estimation problem is more constrained than a 2D-2D pose estimation problem and does not suffer from the limitations associated with computing an essential matrix. The use of correlation-based cost, instead of mutual information as a registration cost, makes it simpler to use gradient-based methods for registration. | 11-04-2010 |
20110128352 | FAST 3D-2D IMAGE REGISTRATION METHOD WITH APPLICATION TO CONTINUOUSLY GUIDED ENDOSCOPY - A novel framework for fast and continuous registration between two imaging modalities is disclosed. The approach makes it possible to completely determine the rigid transformation between multiple sources at real-time or near real-time frame-rates in order to localize the cameras and register the two sources. A disclosed example includes computing or capturing a set of reference images within a known environment, complete with corresponding depth maps and image gradients. The collection of these images and depth maps constitutes the reference source. The second source is a real-time or near-real time source which may include a live video feed. Given one frame from this video feed, and starting from an initial guess of viewpoint, the real-time video frame is warped to the nearest viewing site of the reference source. An image difference is computed between the warped video frame and the reference image. The viewpoint is updated via a Gauss-Newton parameter update and certain of the steps are repeated for each frame until the viewpoint converges or the next video frame becomes available. The final viewpoint gives an estimate of the relative rotation and translation between the camera at that particular video frame and the reference source. The invention has far-reaching applications, particularly in the field of assisted endoscopy, including bronchoscopy and colonoscopy. Other applications include aerial and ground-based navigation. | 06-02-2011 |
20110184238 | IMAGE-BASED GLOBAL REGISTRATION SYSTEM AND METHOD APPLICABLE TO BRONCHOSCOPY GUIDANCE - A global registration system and method identifies bronchoscope position without the need for significant bronchoscope maneuvers, technician intervention, or electromagnetic sensors. Virtual bronchoscopy (VB) renderings of a 3D airway tree are obtained including VB views of branch positions within the airway tree. At least one real bronchoscopic (RB) video frame is received from a bronchoscope inserted into the airway tree. An algorithm according to the invention is executed on a computer to identify the several most likely branch positions having a VB view closest to the received RB view, and the 3D position of the bronchoscope within the airway tree is determined in accordance with the branch position identified in the VB view. The preferred embodiment involves a fast local registration search over all the branches in a global airway-bifurcation search space, with the weighted normalized sum of squares distance metric used for finding the best match. | 07-28-2011 |
20120082351 | FAST 3D-2D IMAGE REGISTRATION METHOD WITH APPLICATION TO CONTINUOUSLY GUIDED ENDOSCOPY - Fast and continuous registration between two imaging modalities makes it possible to completely determine the rigid transformation between multiple sources at real-time or near real-time frame-rates in order to localize video cameras and register the two sources. A set of reference images are computed or captured within a known environment, with corresponding depth maps and image gradients defining a reference source. Given one frame from a real-time or near-real time video feed, and starting from an initial guess of viewpoint, a real-time video frame is warped to the nearest viewing site of the reference source. An image difference is computed between the warped video frame and the reference image. Steps are repeated for each frame until the viewpoint converges or the next video frame becomes available. The final viewpoint gives an estimate of the relative rotation and translation between the camera at that particular video frame and the reference source. | 04-05-2012 |