Patent application number | Description | Published |
20110191014 | MAPPING INTERFACE WITH HIGHER ZOOM LEVEL INSET MAP - Maps of a particular location are often generated with an inset area map, rendered in an inset region of the location map, of the general area including the location at a lower zoom level than the location map. However, this presentation may be disadvantageous in some scenarios (e.g., the where a user is interested in examining the extended area around the location, the area between two locations, or the spatial layout of the locations.) Instead, a composite map may be generated comprising an area map at an area map zoom level, and an inset location map rendered in an inset region of the location map and illustrating a location at a higher zoom level than the area map zoom level. Such composite maps may also be requested programmatically of a map generating service, and may be provided in an automated manner for use in an application. | 08-04-2011 |
20120158738 | Inference Indexing - Methods, systems, and media are provided for facilitating generation of an inference index. In embodiments, a canonical entity is referenced. The canonical entity is associated with web documents. One or more queries that, when input, result in a selection of at least one of the web documents are identified. An entity document is generated for the canonical entity. The entity document includes the identified queries and/or associated text from the content of a document or from an entity title that result in the selection of the at least one of the web documents. The entity document and corresponding canonical entity can be combined with additional related entity documents and canonical entities to generate an inference index. | 06-21-2012 |
20150278370 | TASK COMPLETION FOR NATURAL LANGUAGE INPUT - One or more techniques and/or systems are provided for facilitating task completion. For example, a natural language input (e.g., “where should we eat”) may be received from a user of a client device. The natural language input may be evaluated using a set of user contextual signals, opted-in for exposure by the user for facilitating task completion, to identify a user task intent. For example, a user task intent of viewing a local Mexican restaurant menu may be identified based upon a social network post of the user indicating that the user is meeting a friend for Mexican food. Task completion functionality may be exposed to the user based upon the user task intent. For example, a restaurant app may be deep launched to display a menu of a local Mexican restaurant. | 10-01-2015 |
Patent application number | Description | Published |
20080263056 | ELECTRONIC CONTENT ASSET PUBLICATION SYSTEM - The Electronic Content Asset Publication System operates as an overlay application on the native multi-media communication network to receive individual subscriber requests for a selected electronic content asset and deliver that asset to the requesting subscriber. This system acquires, stores, publishes, distributes, accesses and processes electronic content on demand and delivers this content in the format of the subscriber's communication device over a selected multi-media communications infrastructure. This system provides access to specific subscriber-initiated electronic content assets that are of interest to the subscriber. The electronic content assets comprise individual multi-media streams, multi-media files or streams of multi-media files, initiated and published by individual subscribers rather than the mass media distributed by conventional content sources. | 10-23-2008 |
20080263602 | SYSTEM FOR MANAGING DISTRIBUTED ASSETS IN AN ELECTRONIC CONTENT ASSET PUBLICATION SYSTEM - The Electronic Content Asset Publication System operates as an overlay application on the native multi-media communication network to receive individual subscriber requests for a selected electronic content asset and deliver that asset to the requesting subscriber. This system acquires, stores, publishes, distributes, accesses and processes electronic content on demand and delivers this content in the format of the subscriber's communication device over a selected multi-media communications infrastructure. This system provides access to specific subscriber-initiated electronic content assets that are of interest to the subscriber. The electronic content assets comprise individual multi-media streams, multi-media files, or streams of multi-media files initiated and published by individual subscribers rather than the mass media distributed by conventional content sources. | 10-23-2008 |
20080263603 | USER INTERFACE ARCHITECTURE FOR AN ELECTRONIC CONTENT ASSET PUBLICATION SYSTEM - The Electronic Content Asset Publication System operates as an overlay application on the native multi-media communication network to receive individual subscriber requests for a selected electronic content asset and deliver that asset to the requesting subscriber. This system acquires, stores, publishes, distributes, accesses and processes electronic content on demand and delivers this content in the format of the subscriber's communication device over a selected multi-media communications infrastructure. This system provides access to specific subscriber-initiated electronic content assets that are of interest to the subscriber. The electronic content assets comprise individual multi-media streams, multi-media files or streams of multi-media files, initiated and published by individual subscribers rather than the mass media distributed by conventional content sources. | 10-23-2008 |
20080263604 | PERSONAL CONTENT ARCHIVE OPERABLE IN AN ELECTRONIC CONTENT ASSET PUBLICATION SYSTEM - The Electronic Content Asset Publication System operates as an overlay application on the native multi-media communication network to receive individual subscriber requests for a selected electronic content asset and deliver that asset to the requesting subscriber. This system acquires, stores, publishes, distributes, accesses and processes electronic content on demand and delivers this content in the format of the subscriber's communication device over a selected multi-media communications infrastructure. This system provides access to specific subscriber-initiated electronic content assets that are of interest to the subscriber. The electronic content assets comprise individual multi-media streams, multi-media files or streams of multi-media files, initiated and published by individual subscribers rather than the mass media distributed by conventional content sources. | 10-23-2008 |
20080263610 | SYSTEM FOR DISTRIBUTING ELECTRONIC CONTENT ASSETS OVER COMMUNICATION MEDIA HAVING DIFFERING CHARACTERISTICS - The Electronic Content Asset Publication System operates as an overlay application on the native multi-media communication network to receive individual subscriber requests for a selected electronic content asset and deliver that asset to the requesting subscriber. This system acquires, stores, publishes, distributes, accesses and processes electronic content on demand and delivers this content in the format of the subscriber's communication device over a selected multi-media communications infrastructure. This system provides access to specific subscriber-initiated electronic content assets that are of interest to the subscriber. The electronic content assets comprise individual multi-media streams, multi-media files or streams of multi-media files, initiated and published by individual subscribers rather than the mass media distributed by conventional content sources. | 10-23-2008 |
20090037963 | SYSTEM FOR ELECTRONIC RETAIL SALES OF MULTI-MEDIA ASSETS - The system for electronic retail sales of multi-media assets operates as an overlay application on existing multi-media communication networks to receive individual consumer purchase requests for a selected multi-media asset and deliver a copy of that multi-media asset to the consumer's designated online personal storage space, which represents a network-based consumer multi-media library. In addition, the network-based consumer multi-media library enables the consumer to store consumer generated multi-media assets. The consumer can then access the contents of their network-based consumer multi-media library at any desired time and place, with the consumer selected multi-media asset being delivered to the requesting consumer in a mode appropriate for the consumer's communication device over the multi-media communication network that serves the consumer's presently active communication device. | 02-05-2009 |
20090037964 | SYSTEM FOR ALLOCATING MASS STORAGE FOR VIDEO-ON-DEMAND ASSETS - The Video-on-Demand Asset Mass Storage System provides the capability to determine the current Asset Multiplicity of each Distinct Asset, including identical Distinct Asset copies, and provides the capability to determine the current Asset Multiplicity of each Alias. The implementation maintains Asset Multiplicity measures as the system operates over time, i.e., as the system and its consumers or the operator create and delete Multi-Media Assets or reorganize Video on Demand Library inventories. | 02-05-2009 |
Patent application number | Description | Published |
20100240043 | METHODS OF USING GENETIC VARIANTS TO DIAGNOSE AND PREDICT INFLAMMATORY BOWEL DISEASE - The present invention relates to methods of diagnosing susceptibility to Inflammatory Bowel Disease and subtypes of Inflammatory Bowel Disease. In one embodiment, the present invention provides a method of diagnosing susceptibility to Inflammatory Bowel Disease by determining the presence of one or more risk variants at the DR3 locus, GATA3 locus, SIN(EFS) locus, BTLA locus, LIGHT locus and MAGE locus. | 09-23-2010 |
20110177969 | THE ROLE OF IL17RD AND THE IL23-1L17 PATHWAY IN CROHN'S DISEASE - The present invention relates to methods of diagnosing susceptibility to Crohn's Diseaese by determining the presence or absence of susceptibility variants at the IL17RD locus. in one embodiment, the present invention provides a method of diagnosing and/or predicting susceptibility to Crohn's Disease by determining the presence or absence of an interaction between IL17RD Block 2 Haplotype 2 and IL23R Block 2 Haplotype 2 and/or IL12RB2 Haplotype 4, where the presence of an interaction between IL17RD Block 2 Haplotype 2 and IL23R Block 2 Haplotype 2 and/or IL12RB2 Haplotype 4 is indicative of susceptibility to Crohn's Disease. | 07-21-2011 |
20120190698 | METHODS OF PREDICTING THIOPURINE RESPONSE - The present invention relates to methods of predicting therapeutic efficacy of thiopurines in an individual by determining the presence of one or more risk variants. In one embodiment, the effective therapeutic efficacy of thiopurines is determined by the presence of risk variants at the genetic loci of HLA-DRB1, CREM, TAGAP, PLCL1, GPX4, SBNO2, MEF2A and/or LYSMD4. In another embodiment, the risk variants are located at the genetic loci of ARL4C, IL1R2, JAK2, 19q13, CARD9, SNAPC4, and/or 8q24. In another embodiment, the individual is has been diagnosed with inflammatory bowel disease. | 07-26-2012 |
20120208900 | METHODS OF PREDICTING THE NEED FOR SURGERY IN CROHN'S DISEASE - The present invention relates to methods of predicting susceptibility to a severe form of Crohn's disease in an individual by determining the presence or absence of one or more risk variants. In one embodiment, the risk variants comprise a combination of genetic risk variants and clinical risk factors. In another embodiment, the genetic risk variants are at the IL12B genetic locus. In another embodiment, the severe form of Crohn's disease is characterized by a rapid progression to a condition requiring surgery for treatment. | 08-16-2012 |
20130136720 | METHODS OF USING FUT2 GENETIC VARIANTS TO DIAGNOSE CROHN'S DISEASE - The present invention relates to prognosing, diagnosing and treating of Crohn's disease. The invention also provides prognosis, diagnosis, and treatment that are based upon the presence of one or more genetic risk factors at the FUT2 genetic locus. | 05-30-2013 |
20140017711 | METHODS OF DIAGNOSING ULCERATIVE COLITIS AND CROHN'S DISEASE - The present invention relates to methods of prognosing inflammatory bowel disease (IBD) in an individual by determining the presence of at least one risk genetic variant and/or at least one risk serological marker. In one embodiment, the presence of risk serological marker ANCA is indicative of an aggressive form of ulcerative colitis. In another embodiment, the present invention relates to methods of diagnosing a Crohn's disease subtype in an individual, where the presence of risk variants and serological markers I2, OmpC and/or Cbir1 are indicative of the Crohn's disease subtype. | 01-16-2014 |
20140018447 | METHODS OF DIAGNOSING AND TREATING INTESTINAL GRANULOMAS AND LOW BONE DENSITY IN INFLAMMATORY BOWEL DISEASE - The present invention relates to methods of diagnosing inflammatory bowel disease (IBD) in an individual by determining the presence of at least one risk genetic variant and/or at least one risk serological marker. In one embodiment, the presence of at least one risk genetic variant is indicative of granuloma. In another embodiment, the presence of at least one risk genetic variant is indicative of low bone density (LBD). | 01-16-2014 |
20150337378 | METHODS OF DIAGNOSIS AND TREATMENT OF INFLAMMATORY BOWEL DISEASE - The present invention relates to methods of diagnosing and predicting susceptibility to Crohn's Disease and/or IBD, by determining the presence or absence of susceptibility to genetic variants, risk haplotypes and/or protective haplotypes. In an embodiment, the invention provides methods of diagnosing and/or predicting susceptibility to Crohn's Disease in an individual by determining the presence or absence of risk variants at the IL12RB1, IL12RB2, IL17A, IL17RA, IL17RD and/or IL23R locus. | 11-26-2015 |
20150376707 | METHODS OF DIAGNOSING AND TREATING INFLAMMATORY BOWEL DISEASE - The present invention also provides various methods, kits and compositions for diagnosing, prognosing, and treating various conditions including but not limited to inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease. Also, the present invention provides various methods, kits and compositions for determining susceptibility to or a low probability of various conditions including but not limited to inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease. These methods, kits and compositions may involve detecting risk/protective variants or haplotypes, serological markers, increased or decreased gene methylation, and increased or decreased cytokine secretion. | 12-31-2015 |
20160090629 | VARIANTS OF TNFSF15 AND DCR3 ASSOCIATED WITH CROHN'S DISEASE - Described herein are methods and compositions related to the discovery of associations in TNFSF15 15 and DcR3 genetic loci across in Caucasian, Puerto Rican, and Korean Crohn's Disease, as demonstrated via trans-ethnic fine mapping. The present invention provides methods of quantifying risk and diagnosing susceptibility to Crohn's disease in a subject by determining the presence of one or more risk variants are at the TNFSF15 (or TL1A) and/or DcR3 genetic loci. | 03-31-2016 |
Patent application number | Description | Published |
20110258158 | Data Services Framework Workflow Processing - A data services framework workflow processing system and method is disclosed. The method includes receiving a request for data from a client and based on the request, determining a workflow to process the request. The method also includes based on the workflow, generating a plurality of backend calls. Additionally, the method includes based on the plurality of backend calls, selecting one or more data sources from a plurality of data sources. The method also includes transmitting one or more of the plurality of backend calls to the selected data sources and receiving, from each the selected data sources, a response to the plurality of backend calls. | 10-20-2011 |
20110258635 | Data Services Framework Visibility Component - A data services framework visibility component is disclosed. A method includes receiving a request for data from a client and selecting, based at least in part on the request, a workflow to process the request. The method also includes selecting, based at least in part on the request, a visibility profile. The method also includes based on the request, generating a plurality of backend calls and based on the selected visibility profile, filtering the plurality of backend calls. Additionally, the method includes transmitting one or more of the plurality of filtered backend calls to one or more data sources and receiving, from each of the selected data sources, a response to the plurality of filtered backend calls. The method also includes transmitting the response to the client. | 10-20-2011 |
Patent application number | Description | Published |
20100068697 | PIEZOELECTRIC MICROCANTILEVER SENSORS FOR BIOSENSING - A piezoelectric microcantilever for sensing compounds or molecules. The piezoelectric microcantilever, may include at least one electrode, an insulation layer, a receptor, an immobilization layer, a non-piezoelectric layer and a piezoelectric layer The sensor is capable of self actuation and detection. The piezoelectric layer may be constructed from a highly piezoelectric thin lead magnesium niobate-lead titanate film, a highly piezoelectric thin zirconate titanate film, a highly piezoelectric lead-free film. Methods of using the sensors and flow cells and arrays including the sensors are also described. | 03-18-2010 |
20100216172 | FLOW-BASED ENHANCEMENT OF SPECIFICITY FOR LABEL-FREE BIOCHEMICAL ASSAYS - A label-free biochemical assay, in which label-free interrogation of a target-receptor layer is performed while the target-receptor layer is subjected to a relatively strong flow of an analyte-containing fluid. The volumetric flow rate for the assay is selected based on calibration data corresponding to the target substance, which advantageously results in fewer and/or smaller false-positive signals corresponding to non-target substances compared to those produced with the fluid being stationary. In various embodiments, the label-free interrogation method can be electro-mechanical and/or optical. | 08-26-2010 |
20150105294 | PIEZOELECTRIC MICROCANTILEVER SENSORS FOR BIOSENSING - A piezoelectric microcantilever for sensing compounds or molecules. The piezoelectric microcantilever, may include at least one electrode, an insulation layer, a receptor, an immobilization layer, a non-piezoelectric layer and a piezoelectric layer The sensor is capable of self actuation and detection. The piezoelectric layer may be constructed from a highly piezoelectric thin lead magnesium niobate-lead titanate film, a highly piezoelectric thin zirconate titanate film, a highly piezoelectric lead-free film. Methods of using the sensors and flow cells and arrays including the sensors are also described. | 04-16-2015 |
Patent application number | Description | Published |
20100222287 | Therapeutic Cancer Treatments - Provided are methods for treating prostate cancer by administering a therapeutically effective amount of a hedgehog inhibitor. | 09-02-2010 |
20100286180 | METHODS OF USE OF CYCLOPAMINE ANALOGS - The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula: | 11-11-2010 |
20110230509 | METHODS OF USE FOR CYCLOPAMINE ANALOGS - The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula: | 09-22-2011 |
20120010229 | THERAPEUTIC REGIMENS FOR HEDGEHOG-ASSOCIATED CANCERS - Provided herein are methods, therapeutic regimens, and kits that optimize the benefits of hedgehog inhibition for cancer therapy. | 01-12-2012 |
20120010230 | METHODS AND COMPOSITIONS FOR IDENTIFICATION, ASSESSMENT AND TREATMENT OF CANCERS ASSOCIATED WITH HEDGEHOG SIGNALING - Provided herein are methods, assays and kits for evaluating a sample, e.g., a sample obtained from a cancer patient, to detect one or more hedgehog biomarkers and/or one or more cilium markers. Thus, the invention can be used, inter alia, as a means to identify patients likely to benefit from administration of one or more hedgehog inhibitors, alone or in combination with therapeutic agents; to predict a time course of disease or a probability of a significant event in the disease of a cancer patient; to stratify patient populations; and/or to more effectively treat or prevent a cancer or a tumor associated with hedgehog signaling. | 01-12-2012 |
20120077834 | Methods of Use of Cyclopamine Analogs - The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula: | 03-29-2012 |
20130108582 | METHODS OF USE OF CYCLOPAMINE ANALOGS | 05-02-2013 |
20130108583 | METHODS OF USE FOR CYCLOPAMINE ANALOGS | 05-02-2013 |
20140107142 | METHODS OF USE OF CYCLOPAMINE ANALOGS - The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula: | 04-17-2014 |
20150025012 | METHODS AND COMPOSITIONS FOR IDENTIFICATION, ASSESSMENT AND TREATMENT OF CANCERS ASSOCIATED WITH HEDGEHOG SIGNALING - Provided herein are methods, assays and kits for evaluating a sample, e.g., a sample obtained from a cancer patient, to detect one or more hedgehog biomarkers and/or one or more cilium markers. Thus, the invention can be used, inter alia, as a means to identify patients likely to benefit from administration of one or more hedgehog inhibitors, alone or in combination with therapeutic agents; to predict a time course of disease or a probability of a significant event in the disease of a cancer patient; to stratify patient populations; and/or to more effectively treat or prevent a cancer or a tumor associated with hedgehog signaling. | 01-22-2015 |
Patent application number | Description | Published |
20090304589 | RADIATION SENSITIVE LIPOSOMES - The present invention relates to a radiation sensitive liposome, and the use of this liposome as carrier for therapeutic and diagnostic agent(s). In particular, the invention encompasses a liposome composition comprising a stable liposome-forming lipid and a polymerizable colipid, and a chain transfer agent. The present invention further contemplates methods of diagnosing and treating conditions and diseases that are responsive to liposome-encapsulated or associated agents. | 12-10-2009 |
20110217236 | RADIATION SENSITIVE LIPOSOMES - The present invention relates to a radiation sensitive liposome, and the use of this liposome as carrier for therapeutic and diagnostic agent(s). In particular, the invention encompasses a liposomal delivery system, comprising a stable liposome-forming lipid and a polymerizable colipid, a fraction of which polymerizable colipid polymerizes upon exposure to ionizing, radiation, thereby destabilizing the liposomal membrane. Destabilization of liposomes allows for leakage of liposomal contents. The present invention further contemplates methods of diagnosing and treating conditions and diseases that are responsive to liposome-encapsulated or associated agents. | 09-08-2011 |
20130053618 | RADIATION SENSITIVE LIPOSOMES - The present invention relates to a radiation sensitive liposome, and the use of this liposome as carrier for therapeutic and diagnostic agent(s). In particular, the invention encompasses a liposomal delivery system, comprising a stable liposome-forming lipid and a polymerizable colipid, a fraction of which polymerizable colipid polymerizes upon exposure to ionizing radiation, thereby destabilizing the liposomal membrane. Destabilization of liposomes allows for leakage of liposomal contents. The present invention further contemplates methods of diagnosing and treating conditions and diseases that are responsive to liposome-encapsulated or associated agents. | 02-28-2013 |
Patent application number | Description | Published |
20100072710 | Gas Turbine Seal - A seal is provided for sealing two adjacent components of a gas turbine engine. The seal has first and second sealing surfaces that operate to seal the adjacent components to create an effective seal therebetween. Additionally, the seal has a first end and a second end, with the second end having a necked down portion, which is configured to internally engage the first end in a sliding, overlapping manner. | 03-25-2010 |
20100111671 | METHODS AND APPARATUS INVOLVING SHROUD COOLING - A turbine cooling component comprising a circumferential leading edge, a circumferential trailing edge, a pair of spaced and opposed side panels connected to the leading and trailing edges, an arcuate base connected to the trailing and leading edges having a fore portion, a midsection portion, an aft portion, opposed side portions, an outer surface partially defining a cavity operative to receive pressurized air, and an arcuate inner surface in contact with a gas flow path of a turbine engine, a first side cooling air passage in the base extending along the first side portion from the fore portion to the aft portion, and a fore cooling air passage in the fore portion of the base communicative with the side cooling air passage and the cavity, operative to receive the pressurized air from the cavity. | 05-06-2010 |
20130177383 | DEVICE AND METHOD FOR SEALING A GAS PATH IN A TURBINE - A device for sealing a gas path in a turbine includes a first shroud segment and a slot in a surface of the first shroud segment. A barrier extends inside the slot, and a bypass channel in the slot provides fluid communication between the barrier and the slot to the gas path in the turbine. A method for sealing a gas path in a turbine includes placing a barrier between a first slot in a first shroud segment and a second slot in a second shroud segment and flowing a fluid between the barrier and the first slot to the gas path in the turbine, wherein the fluid flows through a first bypass channel in the first slot. | 07-11-2013 |
20140072418 | FLOATING SEAL - A floating seal assembly for sealing two static parts is disclosed. Each static part has an opposing groove, and the opposing grooves define a seal cavity. Floating seal assembly includes a floating circumferential seal having a middle portion and opposing end portions, each opposing end portion is positioned within a groove in one of the static parts, wherein each end portion has a curved side facing a low pressure side of the seal cavity. The floating seal assembly according to embodiments of the invention is pressure driven in that each curved side of the end portions is configured to engage a low pressure side of the seal cavity in response to a pressure differential across the sealing cavity reaching a threshold value. | 03-13-2014 |
20140169938 | TURBINE PURGE FLOW CONTROL SYSTEM AND RELATED METHOD OF OPERATION - A system configured to precisely control and/or modulate purge flow in a power plant system (e.g., a gas turbine) during operation is disclosed. In one embodiment, a system includes: at least one computing device adapted to control a purge flow in a gas turbine by performing actions comprising: obtaining operational data from the gas turbine; determining an inferred gas path pressure value for the gas turbine; determining an allowable purge flow for the gas turbine as a function of the operational data and the inferred gas path pressure value; and adjusting the purge flow based upon the allowable purge flow determination. | 06-19-2014 |
20140341720 | SEAL SYSTEM INCLUDING ANGULAR FEATURES FOR ROTARY MACHINE COMPONENTS - Systems and devices configured to seal interfaces/gaps between stationary components of turbines and manipulate a flow of coolant about portions of the turbine during turbine operation are disclosed. In one embodiment, a seal element includes: a first surface shaped to be oriented toward a pressurized cavity of the turbine; a second surface oriented substantially opposite the first surface and shaped to sealingly engage a contact surface of the static components; and a first set of angular features disposed in the second surface, the first set of angular features fluidly connecting the pressurized cavity and the flowpath of the turbine. | 11-20-2014 |
Patent application number | Description | Published |
20110152954 | BROACH HANDLE WITH FLEXURE SPRING - An instrument for holding a surgical tool or bone implant includes a handle with a bearing surface formed in one end for engaging the surgical tool. An elastically deformable plate is mounted on the handle body the plate having a catch element formed on a leading end thereof adapted to engage a coupling element formed on the surgical tool. The elastically deformable plate includes a cam follower formed in a recess thereon and includes a deformable spring section intermediate the can elements and the plate end with the catch element. An elongated pivotable loading member is rotatably mounted on the handle body. The loading member includes a cam surface for engaging the cam follower surface on the deformable plate. The cam surface on the loading member is shaped to elastically deform the elastically deformable plate section in a direction away from the plate catch element to thereby load and maintain a connecting force between the plate and the surgical tool or bone implant. | 06-23-2011 |
20130331849 | GLENOSPHERE INSERTER AND IMPACTOR - An impactor for connection to a concave surface of an implant has a shaft extending along a first axis from a first end to a second end. The shaft first end includes a pivot surface surrounding an internal shaft bore. The internal bore extends along the first axis and is open at the first end and extends towards the second end about the first axis. The internal bore has a pin extending through the shaft and intersecting the bore. A resilient element is mounted in the shaft bore spaced towards the shaft second end. A post is mounted in the shaft bore along the first axis. The post has a first end engaging a threaded bore in the concave surface of the implant. The post has a second end engaging the resilient element and a slot therein slidably engaging the pin and a collar pivotally mounted on the shaft. | 12-12-2013 |
20130338675 | GLENOID BASEPLATE INSERTION TOOL - An insertion instrument for inserting an orthopedic implant into a bone and guiding an implant attachment element into the bone comprising: a body having a first end and a second end and a bore extending along a central axis; a fixed arm and a deflectable arm coupled to the body second end, the fixed arm spaced from the deflectable arm forming an attachment element receiving passageway therebetween extending along the central axis, the fixed arm having an implant engaging free end spaced a fixed distance from the central axis; and an actuator mounted on the first end of the body for moving the deflectable arm away from the fixed arm while allowing the attachment element to traverse the passageway. | 12-19-2013 |
20140277190 | COMPRESSION SCREW WITH VARIABLE PITCH THREAD - A bone screw apparatus is provided for threaded engagement with a bone and, optionally, a medical device such as a bone plate. The bone screw has a shaft having a first end, a second end, and a first thread having a first pitch. The screw further includes a head having a proximal end, a distal end adjacent the shaft first end, and a second thread having a second pitch. The second thread has a variable pitch that increases in a proximal direction, but never exceeds the magnitude of any portion of the first pitch. Upon threaded engagement of the head with bone or a medical device, a compression force is generated which continuously decreases as the screw is further inserted. | 09-18-2014 |
20150133943 | RESECTION GUIDE AND METHOD OF POSITIONING - A bone resection guide, which includes a profiling guide. The profiling guide includes a first planar bone contact surface, a first guide surface and at least one outline corresponding to at least a portion of a first implant. | 05-14-2015 |
Patent application number | Description | Published |
20090120852 | Method and apparatus for separating fluid components - A floating element for separating components of a physiological fluid comprises two parts that are relatively movable. The two parts define a prescribed volume between them when at their maximum separation, and one of the parts may be moved toward the other to express the fluid contained in the volume between the parts. The parts are made of materials having densities so that they assume a desired position in the fluid to allow selected components to be easily obtained and expressed. | 05-14-2009 |
20090131877 | Method and apparatus for separating fluid components - A floating element for separating components of a physiological fluid comprises two parts that are relatively movable. The two parts define a prescribed volume between them when at their maximum separation, and one of the parts may be moved toward the other to express the fluid contained in the volume between the parts. The parts are made of materials having densities so that they assume a desired position in the fluid to allow selected components to be easily obtained and expressed. | 05-21-2009 |
20110160031 | DECANTING CENTRIFUGE WITH VIBRATION ISOLATION - A centrifuge has a rotor for receiving a disposable processing unit. The centrifuge is configured such that the motor is attached to an enclosure and the enclosure is supported on a base. The connection between the base and the enclosure is a vibration isolator, and the isolator is positioned such that its effective line of action aligns with the effective plane of rotation of the rotor. In accordance with another feature of the invention, the processing units are held in a decanting position by a decant ring that moves vertically but does not rotate. The ring engages the top of the processing unit during decant and the abrasion is minimal. | 06-30-2011 |
20110319246 | METHOD AND APPARATUS FOR SEPARATING FLUID COMPONENTS - A floating element for separating components of a physiological fluid comprises two parts that are relatively movable. The two parts define a prescribed volume between them when at their maximum separation, and one of the parts may be moved toward the other to express the fluid contained in the volume between the parts. The parts are made of materials having densities so that they assume a desired position in the fluid to allow selected components to be easily obtained and expressed. | 12-29-2011 |
20140135199 | METHOD AND APPARATUS FOR SEPARATING FLUID COMPONENTS - A floating element for separating components of a physiological fluid comprises two parts that are relatively movable. The two parts define a prescribed volume between them when at their maximum separation, and one of the parts may be moved toward the other to express the fluid contained in the volume between the parts. The parts are made of materials having densities so that they assume a desired position in the fluid to allow selected components to be easily obtained and expressed. | 05-15-2014 |
Patent application number | Description | Published |
20130074694 | Bubble-Column Vapor Mixture Condenser - In a bubble-column vapor mixture condenser, a fluid source supplies a carrier-gas stream including a condensable fluid in vapor phase. The condensable fluid in liquid form is contained as a bath in a chamber in each stage of the condenser, and the carrier gas is bubbled through the bath to condense the fluid into the bath. The bubble-column vapor mixture condenser can be used, e.g., in a humidification-dehumidification system for purifying a liquid, such as water. | 03-28-2013 |
20130075940 | Bubble-Column Vapor Mixture Condenser - In a bubble-column vapor mixture condenser, a fluid source supplies a carrier-gas stream including a condensable fluid in vapor phase. The condensable fluid in liquid form is contained as a bath in a chamber in each stage of the condenser, and the carrier gas is bubbled through the bath to condense the fluid into the bath. Energy from condensation is recovered to a liquid composition in a conduit that passes through the liquid in the stages of the condenser. The bubble-column vapor mixture condenser can be used, e.g., in a humidification-dehumidification system for purifying a liquid, such as water. | 03-28-2013 |
20130341810 | Bubble-Column Vapor Mixture Condenser - In a bubble-column vapor mixture condenser, a fluid source supplies a carrier-gas stream including a condensable fluid in vapor phase. The condensable fluid in liquid form is contained as a bath in a chamber in each stage of the condenser, and the carrier gas is bubbled through the bath to condense the condensable fluid into the bath. Energy from condensation is recovered to a coolant in a conduit that passes through the liquid in the stages of the condenser. The bubble-column vapor mixture condenser can be used, e.g., in a humidification-dehumidification system for purifying a liquid, such as water. | 12-26-2013 |
20140014212 | Thermodynamic Balancing of Combined Heat and Mass Exchange Devices - A carrier-gas mixture is directed through a fluid flow path in a combined heat and mass transfer device, which can be operated at sub-atmospheric pressure. Heat and mass are transferred from or to the carrier-gas mixture via interaction with a liquid composition that includes a vaporizable component in a liquid state to substantially change the content of the vaporizable component in the carrier-gas mixture via evaporation or condensation. The mass flow rate of the carrier-gas mixture is varied by extracting or injecting the carrier-gas mixture from at least one intermediate location in the fluid flow path, and/or the mass flow rate of the liquid composition is varied by extracting or injecting the liquid composition from at least one intermediate location in the fluid flow path; and the flow of the carrier-gas mixture or the liquid composition is regulated to reduce the average local enthalpy pinch in the device. | 01-16-2014 |
20150260418 | Humidification-Dehumidification System with a Bubble-Column Vapor Mixture Condenser and Intermediate Gas Extraction - A humidification-dehumidification system comprises a source of liquid; a humidifier including carrier-gas and liquid inlets and outlets and a chamber in which the liquid can contact a carrier gas containing a condensable fluid in vapor phase that is introduced from the carrier-gas inlet in a counterflow arrangement and in which a portion of the liquid can vaporize into the carrier gas; a bubble-column vapor mixture condenser including at least first and second stages, each stage including a carrier-gas inlet and outlet and a chamber configured to contain a liquid bath in fluid communication with the carrier-gas inlet and the carrier-gas outlet; a conduit passing from the source of the liquid through the chamber of each stage of the bubble-column condenser; and an intermediate exchange conduit coupled with (a) the bubble-column vapor mixture condenser and (b) the humidifier chamber at intermediate stages of each for transfer of the carrier gas therebetween. | 09-17-2015 |
20150290557 | Multi-Stage Bubble-Column Vapor Mixture Condenser - A multi-stage bubble-column vapor mixture condenser comprises at least a first stage and a second stage. Each stage includes a carrier-gas inlet and a carrier-gas outlet, as well as a condenser chamber containing a condensing bath in fluid communication with the carrier-gas inlet and the carrier-gas outlet. The carrier-gas inlet is positioned to bubble carrier gas from the carrier-gas inlet up through the condensing bath, overcoming a hydrostatic head of the condensing bath. The carrier-gas outlet is positioned with an opening for carrier-gas extraction above the condensing bath, wherein the first-stage carrier-gas outlet is in fluid communication with the carrier-gas inlet of the second stage to facilitate flow of the carrier gas through the condensing bath in the condenser chamber of the first stage and then through the condensing bath in the condenser chamber of the second stage. | 10-15-2015 |
20160136577 | CONCENTRATION CONTROL IN FILTRATION SYSTEMS, AND ASSOCIATED METHODS - Concentration control in filtration systems and associated methods are generally described. Streams originating from upstream filters and having similar concentrations of a target minor component and/or similar osmotic pressures can be mixed and subsequently filtered within additional filters. Certain embodiments comprise recycling an output stream produced by a filter to a filter feed stream, wherein the output stream and the filter feed stream have similar concentrations of a target minor component and/or similar osmotic pressures. Such strategic mixing and/or recycling can reduce the amount of energy and/or the amount of filtration medium surface area required to achieve a desired concentration of the target minor component in a final product stream. | 05-19-2016 |
20160136578 | FLOW CONTROL IN MULTI-STEP FILTRATION, AND ASSOCIATED SYSTEMS - Flow control in multi-step filtration systems and associated methods are generally described. Certain embodiments are related to methods in which a single filter is used to perform multiple, separate filtration steps. In some cases, a diluted permeate from a first filtration step can be recycled back through the filter, as part of a separate filtration step, to produce a second retentate and a second permeate. Subsequent filtration steps can also be performed. Systems configured to perform multiple, separate filtration steps using a single filter are also described. | 05-19-2016 |
20160136579 | MINOR COMPONENT RATIO BALANCING IN FILTRATION SYSTEMS, AND ASSOCIATED METHODS - Filtration systems in which the ratios of minor components in mixtures can be balanced, and associated methods, are generally described. Certain embodiments are related to methods in which a portion of a retentate stream produced by filtering an initial liquid feed during a first filtration step is mixed with the permeate produced by filtering the permeate from the first filtration step. In some cases, the amount of the first retentate that is mixed with the second permeate is selected such that the ratios of the minor components within the final retentate and permeate streams produced by the filtration system are similar to the ratio of the minor components within the initial liquid. By maintaining similar ratios of minor components, according to certain embodiments, the flavor profile of the initial liquid mixture can be substantially maintained in the concentrated and diluted streams produced by the filtration system. | 05-19-2016 |
Patent application number | Description | Published |
20100243519 | Separation Method and Assembly for Process Streams in Component Separation Units - A method and assembly for utilizing open-cell cellular solid material in a component separation unit to separate one or more process streams into component process streams having desired compositions. A method and assembly for using said open-cell cellular solid material to separate process streams into desired component process streams in a component separation unit, wherein the open-cell cellular solid material can include oxides, carbides, nitrides, borides, ceramics, metals, polymers, and chemical vapor deposition materials. | 09-30-2010 |
20100243520 | Separation Method and Assembly for Process Streams in Component Separation Units - A method and assembly for utilizing open-cell cellular solid material in a component separation unit to separate one or more process streams into component process streams having desired compositions. A method and assembly for using said open-cell cellular solid material to separate process streams into desired component process streams in a component separation unit, wherein the open-cell cellular solid material can include oxides, carbides, nitrides, borides, ceramics, metals, polymers, and chemical vapor deposition materials. | 09-30-2010 |
20130043192 | PROCESS FOR UPGRADING BIOMASS DERIVED PRODUCTS - Disclosed is a process for the alteration of the ratio of the specific gravities of the oil and water phases resulting from the conversion of biomass to liquid products, the reduction of the conductivity and of metals of the product mixture, which each can aid in the removal of solids contained in the oil phase. | 02-21-2013 |
20130333652 | RENEWABLE FUEL COMPOSITION AND METHOD OF USING THE SAME - Disclosed is an alternative fuel composition derived from the conversion of biomass at an elevated temperature, with conversion optionally in the presence of a catalyst, which is capable of reducing, and thereby improving, a low temperature property of a distillate. A process is also disclosed for mixing such renewable composition with the distillate. | 12-19-2013 |
20140142354 | Process of Generating a Renewable Biofuel From a Hydrotreated Stream of Condensed Oxygenates - A renewable fuel may be obtained from a bio-oil containing C | 05-22-2014 |
Patent application number | Description | Published |
20090020411 | Laser pyrolysis with in-flight particle manipulation for powder engineering - Laser pyrolysis apparatuses can provide for the engineering of product inorganic particles in-flight through the use of jet inlets that introduce a composition, such as an inert gas or a surface modifying composition, at high velocity. Under strong mixing conditions, the inorganic particle flow can be manipulated while also reducing particle agglomeration. These strong mixing apparatuses have been found to be effective at forming high quality crystals with structures that inherently grow relatively slowly through the slowing of the quenching process to maintain the crystal development until a desired high degree of crystallinity is achieved. Also, the surface chemistry of the particles can be manipulated in the flow to engineer desired inorganic particle surface chemistry. | 01-22-2009 |
20090075083 | Nanoparticle production and corresponding structures - Methods are described that have the capability of producing submicron/nanoscale particles, in some embodiments dispersible, at high production rates. In some embodiments, the methods result in the production of particles with an average diameter less than about 75 nanometers that are produced at a rate of at least about 35 grams per hour. In other embodiments, the particles are highly uniform. These methods can be used to form particle collections and/or powder coatings. Powder coatings and corresponding methods are described based on the deposition of highly uniform submicron/nanoscale particles. | 03-19-2009 |
20090288601 | COATING FORMATION BY REACTIVE DEPOSITION - Light reactive deposition uses an intense light beam to form particles that are directly coated onto a substrate surface. In some embodiments, a coating apparatus comprising a noncircular reactant inlet, optical elements forming a light path, a first substrate, and a motor connected to the apparatus. The reactant inlet defines a reactant stream path. The light path intersects the reactant stream path at a reaction zone with a product stream path continuing from the reaction zone. The substrate intersects the product stream path. Also, operation of the motor moves the first substrate relative to the product stream. Various broad methods are described for using light driven chemical reactions to produce efficiently highly uniform coatings. | 11-26-2009 |
20100190288 | THIN SILICON OR GERMANIUM SHEETS AND PHOTOVOLATICS FORMED FROM THIN SHEETS - Thin semiconductor foils can be formed using light reactive deposition. These foils can have an average thickness of less than 100 microns. In some embodiments, the semiconductor foils can have a large surface area, such as greater than about 900 square centimeters. The foil can be free standing or releasably held on one surface. The semiconductor foil can comprise elemental silicon, elemental germanium, silicon carbide, doped forms thereof, alloys thereof or mixtures thereof. The foils can be formed using a release layer that can release the foil after its deposition. The foils can be patterned, cut and processed in other ways for the formation of devices. Suitable devices that can be formed form the foils include, for example, photovoltaic modules and display control circuits. | 07-29-2010 |
20100209328 | METHODS FOR SYNTHESIZING SUBMICRON DOPED SILICON PARTICLES - Methods are described that have the capability of producing submicron/nanoscale particles, in some embodiments dispersible, at high production rates. In some embodiments, the methods result in the production of particles with an average diameter less than about 75 nanometers that are produced at a rate of at least about 35 grams per hour. In other embodiments, the particles are highly uniform. These methods can be used to form particle collections and/or powder coatings. Powder coatings and corresponding methods are described based on the deposition of highly uniform submicron/nanoscale particles. | 08-19-2010 |
20120012032 | DISPERSIONS OF SUBMICRON DOPED SILICON PARTICLES - Methods are described that have the capability of producing submicron/nanoscale particles, in some embodiments dispersible, at high production rates. In some embodiments, the methods result in the production of particles with an average diameter less than about 75 nanometers that are produced at a rate of at least about 35 grams per hour. In other embodiments, the particles are highly uniform. These methods can be used to form particle collections and/or powder coatings. Powder coatings and corresponding methods are described based on the deposition of highly uniform submicron/nanoscale particles. | 01-19-2012 |
20120244060 | METHODS FOR SYNTHESIZING SUBMICRON DOPED SILICON PARTICLES - Methods are described that have the capability of producing submicron/nanoscale particles, in some embodiments dispersible, at high production rates. In some embodiments, the methods result in the production of particles with an average diameter less than about 75 nanometers that are produced at a rate of at least about 35 grams per hour. In other embodiments, the particles are highly uniform. These methods can be used to form particle collections and/or powder coatings. Powder coatings and corresponding methods are described based on the deposition of highly uniform submicron/nanoscale particles. | 09-27-2012 |