Patent application number | Description | Published |
20080297475 | Input Device Having Multifunctional Keys - The invention relates to an input device having multifunctional keys, wherein the different functions are triggered by varying the pressure on the keys or by varying the depth to which the key is depressed or the distance it is moved (see FIG. | 12-04-2008 |
20090206084 | PROGRAMMABLE LIQUID CONTAINERS - The invention relates to liquid containers comprising a plurality of sealed additive chambers in communication with a vessel tillable with a liquid. The additive chambers comprise independently selected additives that may be added to a liquid in the container at the option of the user. The user can manually open the additive chambers of their choice and release the additive into a liquid in the vessel without destroying the integrity of the container. In this manner, the liquid containers are programmable by the users and various aspects of the liquid in the container, such as color and/or flavor, is controlled by the user. | 08-20-2009 |
20090327888 | COMPUTER PROGRAM FOR INDENTIFYING AND AUTOMATING REPETITIVE USER INPUTS - The invention relates to machine-readable code that tracks user input and associated computer output during use of a computer programmed with the code, identifies repetitive patterns and automates the user input portion of those identified repetitive patterns when they occur again. | 12-31-2009 |
20110161054 | Systems And Methods For Computer Aided Inventing - Methods and systems are provided for a systematic approach to computer aided inventing. In a modeling environment, a model representing any item, composition or process can be defined and configured using the lexicon and specification of an innovation database. In the model, objects can be identified, defined, and configured to provide the model with constituent products, components, features and materials. An innovation engine automatically applies one or more morphs from the innovation database to the objects of the model to generate morphed versions of the model that may provide innovations of or inventions to the item, composition or process represented by the model. | 06-30-2011 |
20120298532 | PROGRAMMABLE LIQUID CONTAINERS - The invention relates to liquid containers comprising a plurality of sealed additive chambers in communication with a vessel fillable with a liquid. The additive chambers comprise independently selected additives that may be added to a liquid in the container at the option of the user. The user can manually open the additive chambers of their choice and release the additive into a liquid in the vessel without destroying the integrity of the container. In this manner, the liquid containers are programmable by the users and various aspects of the liquid in the container, such as color and/or flavor, is controlled by the user. | 11-29-2012 |
20130013268 | METHOD AND SYSTEM FOR COMPUTER AIDED INVENTING - Methods and systems are provided for a systematic approach to computer aided inventing. In a modeling environment, a model representing an item, composition or process can be defined and configured using the lexicon and specification of an innovation database. In the model, objects can be indentified, defined, and configured to provide the model with constituent products, components, features and materials. An innovation engine automatically applies one or more morphs from the innovation database to the objects or the model to generate morphed versions of the model that may provide innovations of, or invention to, the item, composition or process represented by the model. | 01-10-2013 |
20140346063 | PROGRAMMABLE LIQUID CONTAINERS - The invention relates to liquid containers comprising a plurality of sealed additive chambers in communication with a vessel tillable with a liquid. The additive chambers comprise independently selected additives that may be added to a liquid in the container at the option of the user. The user can manually open the additive chambers of their choice and release the additive into a liquid in the vessel without destroying the integrity of the container. In this manner, the liquid containers are programmable by the users and various aspects of the liquid in the container, such as color and/or flavor, is controlled by the user. | 11-27-2014 |
Patent application number | Description | Published |
20120083327 | Symbol and Reel Substitution Methods for Multi-Line Slot Machines - A method of operating a slot machine, and a slot machine in which the method may be used. One or more symbols on a reel are replaced with symbols prescribed by a selected schema. The schema may be selected randomly, or according to a weighted probability, or according to a count of recent plays. All symbols of one type may be replaced with one other type of symbol, or with a variety of different symbols as prescribed by the schema. A symbol stack may be replaced with another symbol stack. Symbols may be replaced on one, several, or all of the reels that make up the display. | 04-05-2012 |
20120329556 | METHOD OF OPERATING AN ONLINE GAME USING CONSOLIDATED GAME OBJECTS - The present invention provides methods for playing a multi-player, online game in which players build virtual worlds by placing game objects into a game space and may consolidate multiple game objects into a single object such that the new consolidated object maintains some or all of the features of the original, separate objects but occupies less game space. | 12-27-2012 |
20140221101 | Consolidating Businesses in a Gamespace for an Online Game - Software receives a command from a player selecting one or more businesses from a game menu in an online game that is a builder-type game. The software then receives a command from the player identifying an empty location in a game space for the game. The software causes the one or more businesses to be displayed in the game space at the location and receives a command from the player selecting a plurality of displayed businesses. The software then receives a command from the player to consolidate the displayed businesses that were selected into a consolidated business and displays the consolidated business in the game space. | 08-07-2014 |
20140364192 | Gaming System and Method of Gaming - A gaming system is disclosed that comprises a symbol selector arranged to select a plurality of base symbols from a set of base symbols for display in a display area; and at least one set of additional symbols, each set of additional symbols including a plurality of additional symbols. The gaming system is arranged to incorporate the additional symbols of an additional symbol set into the base symbol set so as to define a combined symbol set, and the gaming system is arranged to select and display a plurality of base and/or additional symbols from the combined symbol set. The gaming system further comprises an outcome evaluator arranged to determine a game outcome based on the selected base and/or additional symbols. | 12-11-2014 |
Patent application number | Description | Published |
20100102467 | POLYMER UNDERWATER MELT CUTTER AND PROCESSES ASSOCIATED THEREWITH - In an improved polymer melt cutter a gas is added to the cooling liquid before the cooling liquid enters the cutting chamber, or is added directly through the cutting chamber wall. This forms a cooling liquid/gas mixture in the cutting chamber, which has the advantage of providing easier startups, lower operating costs, and other advantages. Processes associated with the improved polymer melt cutter are also disclosed. | 04-29-2010 |
20120329976 | PROCESS FOR PREPARING POLYAMIDES COMPRISING FLUOROETHER FUNCTIONALIZED AROMATIC MOIETIES - The invention is directed to a process for preparing polyamide polymers, particularly nylon 6, 6 and nylon 6, comprising fluoroether functionalized aromatic repeat units. In one embodiment, 1,6 diaminohexane, adipic acid, and fluoroether functionalized terephthallic or isophthallic acid or diester are reacted to form a polymer. The polymers so formed are useful for imparting soil resistance to polyamides, particularly in the form of films, molded parts, fibers, fabrics, and carpets. | 12-27-2012 |
20140066568 | POLYAMIDE RESIN BLENDS - Disclosed is a polyamide resin blend including:
| 03-06-2014 |
20140329984 | POLYMERS DERIVED FROM RENEWABLY RESOURCED LYSINOL - Disclosed are salt compositions of lysinol and dicarboxylic acids; and lysinol derived polymers including polyamide, polyimide, polyurea, cross-linked polyurea comprising urethane linkages, polyurea foams, cross-linked polyurea foams, and lysinol-epoxy thermoset. | 11-06-2014 |
Patent application number | Description | Published |
20110092569 | Administration of Exogenous mi/siRNA - Certain genes controlled by endogenous miRNA are actually upregulated upon the transfection of exogenous mi/siRNA. Based on this, methods of determining whether administration of mi/siRNA will have a deleterious effect by upregulating certain genes are provided. Comparison of sequences of exogenous mi/siRNA allows selection of exogenous miRNA to be administered to cell to enhance or limit this affect, and therefore to control unwanted disregulation, or to upregulate an endogenous miRNA-regulated gene of interest. | 04-21-2011 |
20130303383 | METHODS AND APPARATUS FOR PREDICTING PROTEIN STRUCTURE - The present invention relates to a method for predicting three-dimensional structure of a protein from its sequence. Three-dimensional structure may be determined by: (a) generating a multiple sequence alignment for a candidate protein having a known sequence; (b) identifying a covariance matrix between all pairs of sequence positions in the multiple sequence alignment; (c) inverting the covariance matrix and identifying predicted evolutionary constraints using a statistical model of the candidate protein; and (d) simulating folding of an extended chain structure of the candidate protein using the predicted constraints. | 11-14-2013 |
20130303387 | METHODS AND APPARATUS FOR PREDICTING PROTEIN STRUCTURE - The present invention relates to a method for predicting three-dimensional structure of a protein from its sequence. Three-dimensional structure may be determined by: (a) generating a multiple sequence alignment for a candidate protein having a known sequence; (b) identifying a covariance matrix between all pairs of sequence positions in the multiple sequence alignment; (c) inverting the covariance matrix and identifying predicted evolutionary constraints using a statistical model of the candidate protein; and (d) simulating folding of an extended chain structure of the candidate protein using the predicted constraints. | 11-14-2013 |
20130304432 | METHODS AND APPARATUS FOR PREDICTING PROTEIN STRUCTURE - The present invention relates to a method for predicting three-dimensional structure of a protein from its sequence. Three-dimensional structure may be determined by: (a) generating a multiple sequence alignment for a candidate protein having a known sequence; (b) identifying a covariance matrix between all pairs of sequence positions in the multiple sequence alignment; (c) inverting the covariance matrix and identifying predicted evolutionary constraints using a statistical model of the candidate protein; and (d) simulating folding of an extended chain structure of the candidate protein using the predicted constraints. | 11-14-2013 |
Patent application number | Description | Published |
20080303367 | VARIABLE SPEED CONSTANT FREQUENCY MOTOR - A variable speed isosychronized motor includes two annular stators conformed for variable angular alignment relative to each other and a common rotor extending a plurality of isolated loops to cross-induce power between stators once such are angularly displaced. In this form of losses, attendant to speed variation through stator phasing are reduced. Electrical compensation may be inserted between each terminal pair. Potentiometers in parallel with capacitors and may be inserted between the respective terminals to expand the operating range of the device. | 12-11-2008 |
20100026122 | VARIABLE SPEED CONSTANT FREQUENCY MOTOR - A variable speed isosychronized motor includes two annular stators conformed for variable angular alignment relative to each other and a common rotor extending a plurality of isolated loops to cross-induce power between stators once such are angularly displaced. In this form of losses, attendant to speed variation through stator phasing are reduced. Electrical compensation may be inserted between each terminal pair. Potentiometers in parallel with capacitors and may be inserted between the respective terminals to expand the operating range of the device. | 02-04-2010 |
20110140555 | VARIABLE SPEED CONSTANT FREQUENCY MOTOR - A variable speed isosychronized motor includes two annular stators conformed for variable angular alignment relative to each other and a common rotor extending a plurality of isolated loops to cross-induce power between stators once such are angularly displaced. In this form of losses, attendant to speed variation through stator phasing are reduced. Electrical compensation may be inserted between each terminal pair. Potentiometers in parallel with capacitors and may be inserted between the respective terminals to expand the operating range of the device. | 06-16-2011 |
20110140560 | METHOD AND APPARATUS FOR COMPENSATING A LINE SYNCHRONOUS GENERATOR - A three-phase line synchronous generator with an exciter and generator stage. The exciter stage includes an exciter stator having n poles and an exciter rotor having n poles and disposed for rotation within the exciter stator, and the generator stage includes a generator stator having n poles and a generator rotor having n poles. The generator rotor being mechanically coupled to the exciter rotor and disposed for rotation within the generator stator, wherein the poles of the stators, or the poles of the rotors, are angularly displace by one pole pitch. | 06-16-2011 |
20130181561 | METHOD AND APPARATUS FOR COMPENSATING A LINE SYNCHRONOUS GENERATOR - A three-phase line synchronous generator with an exciter and generator stage. The exciter stage includes an exciter stator having n poles and an exciter rotor having n poles and disposed for rotation within the exciter stator, and the generator stage includes a generator stator having n poles and a generator rotor having n poles. The generator rotor being mechanically coupled to the exciter rotor and disposed for rotation within the generator stator, wherein the poles of the stators, or the poles of the rotors, are angularly displace by one pole pitch. | 07-18-2013 |
20140145536 | METHOD AND APPARATUS FOR COMPENSATING A LINE SYNCHRONOUS GENERATOR - A three-phase line synchronous generator with an exciter and generator stage. The exciter stage includes an exciter stator having n poles and an exciter rotor having n poles and disposed for rotation within the exciter stator, and the generator stage includes a generator stator having n poles and a generator rotor having n poles. The generator rotor being mechanically coupled to the exciter rotor and disposed for rotation within the generator stator, wherein the poles of the stators, or the poles of the rotors, are angularly displace by one pole pitch. | 05-29-2014 |
Patent application number | Description | Published |
20120138558 | Drum Rack - A foldable rack includes at least two segments rotatably coupled to one another such that the foldable rack can achieve a folded configuration and an operational configuration, the folded configuration being more compact than the operational position. The rack can be configured to support musical instruments such as cymbals, drums and the like and provide for adjustability of their positions while maintaining a clear and uncluttered appearance by concealing any electrical cabling involved. | 06-07-2012 |
20120144980 | SYSTEM AND METHOD FOR ELECTRONIC PROCESSING OF CYMBAL VIBRATION - In one embodiment, an electronic cymbal system includes a first pickup configured to generate an electrical signal representative of vibrations in a first cymbal, and a controller configured to receive the first electrical signal and to process the first electrical signal to generate an output. The controller includes a digital signal processor (DSP) configured to subject a version of the first electrical signal to a digital signal processing technique. The digital signal processing technique includes one or more of dynamic range compression, expansion, frequency equalization, harmonic excitation, comb filtering, and pitch shifting. The cymbals may be any of variety of known cymbals, such as hi-hat, crash and ride cymbals, and may be of the perforated type configured to reduce noise for indoor use. Lighting control may be provided to illuminate the cymbal for functional or aesthetic purposes. | 06-14-2012 |
20120186419 | SYSTEM AND METHOD FOR ELECTRONIC PROCESSING OF CYMBAL VIBRATION - In one embodiment, an electronic cymbal system includes a first pickup configured to generate an electrical signal representative of vibrations in a first cymbal, and a controller configured to receive the first electrical signal and to process the first electrical signal to generate an output. The controller includes a digital signal processor (DSP) configured to subject a version of the first electrical signal to a digital signal processing technique. The digital signal processing technique includes one or more of dynamic range compression, expansion, frequency equalization, harmonic excitation, comb filtering, and pitch shifting. The cymbals may be any of variety of known cymbals, such as hi-hat, crash and ride cymbals, and may be of the perforated type configured to reduce noise for indoor use. Lighting control may be provided to illuminate the cymbal for functional or aesthetic purposes. | 07-26-2012 |
Patent application number | Description | Published |
20110035456 | METHODS AND ARRANGEMENTS FOR CONTENT FILTERING - Systems and arrangements are provided for filtering language. As presently preferred, these are configured to filter inappropriate language, symbols, words, etc on web sites or used in chat rooms. Embodiments create one or more arrays of inappropriate character strings representing, for example, obscene words and character combinations. Embodiments identify the inappropriate character strings, for example in chat text, and edit them to an appropriate form, for example with cartoon characters, and/or delete the inappropriate character strings. Preferably, at least one embodiment applies the content filter via executing a program of instructions, stored on a tangible storage medium, to achieve this functionality. | 02-10-2011 |
20120079390 | Method and Apparatus of Graphical Object Selection in a Web Browser - Various approaches for selection of graphical objects in a web browser-based application are described. In one approach, a selection overlay is stored in a web document. The selection overlay encompasses a plurality of user-selectable graphical objects in the web document occupies a highest position in layers of graphical objects in the web document and includes a plurality of selection regions. Each selection region is respectively associated with one of the plurality of graphical objects and defines a region of selectability for the associated graphical object. In response to the web browser-based application detecting entry of a user-directed pointer into one of the selection regions in the selection overlay, the graphical object associated with the one selection region is selected for user manipulation and displayed. | 03-29-2012 |
20120159348 | MOSAIC GENERATION FROM USER-CREATED CONTENT - Techniques for creating a mosaic using user-created content on a content sharing site. Embodiments of the invention may provide an interface on the content sharing site to allow users to create content. Embodiments may then determine a suitability value between the user-created content and portions of a mosaic, and insert the user-created content into a particular portion of the mosaic based on the determined suitability value for the particular portion. | 06-21-2012 |
Patent application number | Description | Published |
20100241014 | DEVICE FOR NON-INVASIVE MEASUREMENT OF BLOOD PRESSURE AND ANKLE-BRACHIAL INDEX - A device for non-invasive measurement of blood pressure includes a blood pressure cuff, a plethysmographic electrode for acquiring an impedance plethysmogram distal to the cuff and a processing device to inflate and deflate the cuff, generate the impedance plethysmogram and to determine the systolic and diastolic blood pressures. It is determined when the cuff is completely occluding the extremity, e.g., by detecting pulses at a second, partially occluded cuff or by a photoplethysmogram attached to the big toe. The device can be used to measure systolic or diastolic blood pressure or both. It can also be used to take ankle-brachial measurements. An autocorrelation technique can be used to correct noise. | 09-23-2010 |
20100329794 | METHOD OF AND APPARATUS FOR BOUYANCY COMPENSATION FOR DIVERS - An improved buoyancy compensation device having a lesser change in buoyancy with depth than conventional buoyancy compensation devices which use ambient pressure bladders is disclosed. The improved device comprises one or more elastic members that, throughout the working range of diving pressures and volumes, is always elastic and, when pressurized, maintains an internal air pressure that is always greater than the ambient pressure at any dive depth. The invention also relates to a method of providing a buoyancy compensation device with an elastic member having a lift versus depth characteristic that approaches the lift versus depth characteristic of a constant or fixed volume buoyancy compensation device. | 12-30-2010 |
20110060201 | Integrated Pulse Oximeter-Pulse Flowmeter - This device uses electrical impedance and signal processing to measure the small change in volume (“Pulse Volume”) of a limb-segment that occurs with each heartbeat. “Pulsatile Flow” is defined as the pulse volume multiplied by the heart rate and is an index of tissue perfusion. This information can be combined with measured blood oxygen saturation to determine how much oxygen is reaching the tissues. The combination of knowing oxygen saturation and tissue perfusion is far more useful than knowing just one or the other of these parameters. | 03-10-2011 |
Patent application number | Description | Published |
20100270327 | LIQUID STORAGE TANK WITH INTERNAL FLOW CONTROL BAFFLE AND METHODS - A liquid storage tank assembly includes a baffle member and a tank assembly. The baffle member includes a generally helical or spiral shaped portion. The baffle member defines a spiral flow path between inlet and outlet openings of the tank assembly. When the baffle member is positioned within the tank and the tank assembly holds a volume of a first liquid, input of a supply of a second liquid at the inlet to the tank assembly forces the first liquid along the spiral flow path and out of the tank assembly exit without substantial mixing of the first and second liquids before substantially all of the first liquid has been dispensed. | 10-28-2010 |
20110259812 | FILTER ELEMENT AND SEAL THEREFOR - A filter cell element for use in a housing to form a filtering assembly. The filter element has a media pack having an interior and a separator element having a passage therein for radial fluid communication between the media pack interior and an edge of the media pack. An overmold seal at the media pack edge seals the media pack to the separator element. Methods of making the filter element and methods of using are also disclosed. | 10-27-2011 |
20120279916 | FILTER CARTRIDGE WITH ANTI-DRIP FEATURE - A filter cartridge is disclosed comprising a housing comprising a terminal end, a connective end, and a longitudinal axis, the connective end comprising a fluid inlet and a fluid outlet. The filter cartridge further comprises a filtration media disposed within the housing between the terminal end and the connective end and fluidly connecting the fluid inlet to the fluid outlet. One of the fluid inlet or the fluid outlet comprises one or more anti-drip capillary channels, the transverse cross-section of the anti-drip capillary channels being elongate in at least one direction. | 11-08-2012 |
20140353455 | REMOVABLE WALL DECORATION KITS, SYSTEMS AND METHODS - Systems and kits for decorating walls include a plurality of décor assemblies and a plurality of complementary fastening structures. The décor assemblies include a décor element and a releasable fastening structure providing first fastening elements. The complementary fastening structure includes a base, a pressure sensitive adhesive disposed on the base, and second fastening elements. The first fastening elements are releasably mateable with the second fastening elements to define a releasable fastening system. During use, a complementary fastening structure is releasably applied to a wall, and is connected to and supports one of the décor assemblies via the releasable fastening system. The releasable fastening system can comprise low profile hooks and loops, exhibiting relatively low holding power. | 12-04-2014 |
Patent application number | Description | Published |
20090126842 | TIRE WITH ZONED BUILT-IN SEALANT LAYER - The present invention relates to a pneumatic tire which contains a built-in zoned puncture sealant layer. The zoned puncture sealant layer is comprised of organoperoxide depolymerized butyl rubber zones comprised of a central primary zone and lateral zones joined together to form a unitary sealant layer. The sealant of the lateral zones of the sealant layer is of a higher storage modulus (G′) than the sealant of the central zone. | 05-21-2009 |
20100154959 | METHOD AND APPARATUS FOR BUILDING A TIRE HAVING A PUNCTURE SEALANT - A tire with a built in sealant comprising: sidewalls, a supporting tire carcass comprised of one or more layers of ply, a pair of beads, and an outer circumferential tread, wherein the sidewalls extend radially inward from the axial outer edges of the tread portion to join the respective beads, and a layer of sealant disposed between the inner liner and a cover layer, the carcass of the tire has a radially innermost layer, wherein the sealant is located over said gas permeable liner, and has a first outer edge and a second outer edge, wherein on each side of said sealant adjoining with the first outer edge and the second outer edge is two or more layers of butyl rubber inner liner. | 06-24-2010 |
20130061995 | METHOD AND APPARATUS FOR MAKING A COMPARTMENTALIZED TIRE SEALANT STRIP - A method for making a compartmentalized sealant strip and barrier assembly | 03-14-2013 |
20140060718 | METHOD AND APPARATUS FOR MAKING A COMPARTMENTALIZED TIRE SEALANT STRIP - A method for making a compartmentalized sealant strip and barrier assembly | 03-06-2014 |
20150059952 | FILTER ASSEMBLY FOR AIR MAINTENANCE TIRE - A tire assembly is disclosed, wherein the tire has a tread portion and a pair of sidewalls extending radially inward from the tread portion to join with a respective bead; a supporting carcass for the tread portion and sidewalls; and a pump passageway positioned within a bending region of the tire. The pump passageway is operative to open and close as the tire rotates. The tire assembly further includes a valve assembly in fluid communication with the pump passageway. The tire further includes a pocket formed in the tire, and a filter assembly is mounted in the pocket. The filter assembly is in air flow communication with the valve assembly, wherein the filter assembly is formed of a housing and a cover, wherein the cover has one or more holes for communicating air into the housing, wherein the cover is connected to the housing, the housing having an interior cavity having a filter media housed therein, the housing having a hole in fluid communication with the valve assembly, wherein a flexible collar surrounds the cover. | 03-05-2015 |
Patent application number | Description | Published |
20080221308 | HDAC9 polypeptides and polynucleotides and uses thereof - The present invention features substantially pure HDAC9, HDAC9a, HDAC9(ΔNLS), HDAC9a(ΔNLS), an HDRP(ΔNLS) polypeptides, and isolated nucleic acid molecules encoding those polypeptides. The present invention also features vectors containing HDAC9, HDAC9a, HDAC9(ΔNLS), HDAC9a(ΔNLS), and HDRP(ΔNLS) nucleic acid sequences, and cells containing those vectors. | 09-11-2008 |
20090054720 | Use of histone deacetylase inhibitors in combination with radiation for the treatment of cancer - The present invention relates to a method for the treatment of cancer in a patient in need thereof. The method comprises administering to a patient in need thereof a first amount of a histone deacetylase inhibitor in a first treatment procedure, and a second amount or dose of radiation in a second treatment procedure. The first and second treatments together comprise a therapeutically effective amount. The combination of the HDAC inhibitor and radiation therapy is therapeutically synergistic. | 02-26-2009 |
20100273732 | COMBINATION METHODS OF TREATING CANCER - The present invention relates to a method of treating cancer in a subject in need thereof, by administering to a subject in need thereof a first amount of a histone deacetylase (HDAC) inhibitor or a pharmaceutically acceptable salt or hydrate thereof, in a first treatment procedure, and a second amount of an anti-cancer agent in a second treatment procedure. The first and second amounts together comprise a therapeutically effective amount. The effect of the HDAC inhibitor and the anti-cancer agent may be additive or synergistic. | 10-28-2010 |
20110124731 | Treatment Of Neurodegenerative Diseases And Cancer Of The Brain Using Histone Deacetylase Inhibitors - The present application is directed to a method of treating diseases of the central nervous system (CNS) comprising administering to a individual in need of treatment a therapeutically effective amount of an inhibitor of histone deacetylase. In particular embodiments, the CNS disease is a neurodegenerative disease. In further embodiments, the neurogenerative disease is an inherited neurodegenerative disease, such as those inherited neurodegenerative diseases which are polyglutamine expansion diseases. The individual can be a mammal such as a primate or human. | 05-26-2011 |
20120270818 | HDAC 6 INHIBITOR-BASED METHODS FOR TREATING CANCER - This invention provides methods for treating a subject afflicted with cancer, comprising concurrently administering (i) an HDAC 6-selective inhibitor and (ii) a suitable cytotoxic agent such as SAHA, doxorubicin or etoposide. This invention also provides methods for inducing the death of a transformed cell such as a cancer cell, comprising concurrently contacting the cell with (i) an HDAC 6-selective inhibitor and (ii) a suitable cytotoxic agent such as SAHA, doxorubicin or etoposide. | 10-25-2012 |
20140031368 | SELECTIVE HDAC INHIBITORS - This disclosure is related to compounds having the structure | 01-30-2014 |
20140288119 | NOVEL MOLECULES THAT SELECTIVELY INHIBIT HISTONE DEACETYLASE 6 RELATIVE TO HISTONE DEACETYLASE 1 - This invention provides a compound having the structure: | 09-25-2014 |
Patent application number | Description | Published |
20080199428 | Treatment of Liver Diseases in Which Iron Plays a Role in Pathogenesis - The invention relates to the use of 4-[3,5-Bis-(2-hydroxyphenyl)-[1,2,4]-triazol-1-yl]benzoic acid (hereinafter referred to as “Compound I”) for the manufacture of pharmaceutical compositions for the treatment of liver diseases in humans in which iron plays a role in pathogenesis, including viral diseases, such as chronic hepatitis C, optionally in conjunction with antiviral agents and for the treatment of non viral diseases, such as non-alcoholic steatohepatitis and non-alcoholic fatty liver disease. | 08-21-2008 |
20100098662 | TREATMENT OF LIVER DISEASES IN WHICH IRON PLAYS A ROLE IN PATHOGENESIS - The invention relates to the use of 4-[3,5-Bis-(2-hydroxyphenyl)-[1,2,4]-triazol-1-yl]benzoic acid (hereinafter referred to as “Compound I”) for the manufacture of pharmaceutical compositions for the treatment of liver diseases in humans in which iron plays a role in pathogenesis, including viral diseases, such as chronic hepatitis C, optionally in conjunction with antiviral agents and for the treatment of non viral diseases, such as non-alcoholic steatohepatitis and non-alcoholic fatty liver disease. | 04-22-2010 |
20130109730 | TREATMENT OF LIVER DISEASES IN WHICH IRON PLAYS A ROLE IN PATHOGENESIS | 05-02-2013 |
Patent application number | Description | Published |
20120247296 | WATERJET CUTTING SYSTEM FLUID CONDUITS AND ASSOCIATED METHODS - Various embodiments of waterjet cutting systems are described herein. In one embodiment, a waterjet cutting system includes a waterjet cutting device coupled to a pressurized water source. The waterjet cutting device includes a waterjet cutting head and a fluid conduit configured to carry pressurized water to the waterjet cutting head. The fluid conduit has a wall defining a longitudinal passage through which the pressurized water travels. The fluid conduit also has a through hole extending from the outer surface of the wall to the longitudinal passage. The through hole has a cross-sectional shape with a maximum longitudinal dimension generally parallel to the longitudinal passage and a maximum latitudinal dimension generally perpendicular to the longitudinal passage. In one aspect of this embodiment, the maximum longitudinal dimension is greater than the maximum latitudinal dimension. Methods of forming fluid conduits according to various embodiments are also described herein. | 10-04-2012 |
20140051334 | CONTROL VALVES FOR WATERJET SYSTEMS AND RELATED DEVICES, SYSTEMS AND METHODS - Control valves for waterjet systems, control-valve actuators, waterjet systems, methods for operating waterjet systems, and associated devices, systems, and methods are disclosed. A control valve configured in accordance with a particular embodiment includes a first seat having a tapered inner surface, a second seat having a contact surface, and an elongated pin having a shaft portion and an end portion. The pin is movable relative to the first and second seats between a shutoff position and one or more throttling positions. When the pin is at the shutoff position, the end portion of the pin is in contact with the contact surface. When the pin is at the throttling position, the end portion of the pin is spaced apart from the contact surface and the tapered inner surface and the shaft portion of the pin at least partially define a throttling gap. | 02-20-2014 |
20140087631 | CONTROL VALVES FOR WATERJET SYSTEMS AND RELATED DEVICES, SYSTEMS, AND METHODS - Waterjet systems including control valves and associated devices, systems, and methods are disclosed. A waterjet system configured in accordance with a particular embodiment includes a fluid source, a jet outlet, and a fluid conveyance extending from the fluid source to the jet outlet. The system further includes a control valve positioned along the fluid conveyance downstream from the fluid source and upstream from the jet outlet. The fluid conveyance has a first portion upstream from the control valve and a second portion downstream from the control valve. The control valve is configured to controllably reduce a pressure of fluid within the second portion of the fluid conveyance relative to a pressure of fluid within the first portion of the fluid conveyance. The first portion of the fluid conveyance is configured to accommodate movement of the jet outlet relative to the fluid source. | 03-27-2014 |
Patent application number | Description | Published |
20110128913 | PROVIDING PROXY MOBILE IP OVER A COMMUNICATION NETWORK - Methods and systems for providing interconnection between network operation environments are disclosed in some embodiments. This can include providing interoperability between 3GPP and 3GPP2 standards environments. In one embodiment, a method is disclosed that includes receiving a request from a mobile device for service at a gateway, determining a mode of operation for the mobile device by inspecting an incoming message, wherein the mode of operation includes 3GPP and 3GPP2, establishing a connection using a proxy mobile internet protocol (PMIP), where the type of connection established is dependent on the mode of operation, providing an IP address to a mobile device based on the mode of operation and the parameters associated with the mode of operation, and communicating with an authentication, authorization, and accounting (AAA) server operating in accordance with the mode of operation. | 06-02-2011 |
20110286465 | MULTI-TIERED PAGING SUPPORT USING PAGING PRIORITY - Prioritization of data traffic is a common technique for providing enhanced quality of service (QoS), allowing some traffic to reach its destination on an expedited basis without being obstructed or delayed by other lower-priority traffic. A mechanism is disclosed using the bearer architecture of the evolved packet core (EPC) to provide prioritization of traffic from specific packet data networks (PDNs), as well as over specific bearers. The priority information is requested by the mobile management entity (MME), which is commonly overloaded with traffic to and from multiple users and PDNs. In addition, a mechanism is provided for reducing the frequency of unwanted paging notifications for MMEs that are overloaded. | 11-24-2011 |
Patent application number | Description | Published |
20090116427 | ADVANCED TECHNOLOGY FRAME STRUCTURE WITH BACKWARD COMPATIBILITY - An advanced technology frame structure is described herein. The advanced technology frame structure can enhance a first technology frame structure in dimensions of time, frequency, or a combination of time and frequency. A second technology frame structure time division multiplexes second technology subframes with the first technology downlink and uplink subframes. The first technology downlink subframe can be divided into a first technology downlink subframe and one or more second technology downlink subframes. Similarly, the first technology uplink subframe can be divided into a first uplink subframe and one or more second technology uplink subframes. These principles can be expanded upon and can be applied in many communication systems. | 05-07-2009 |
20120140730 | ADVANCED TECHNOLOGY FRAME STRUCTURE WITH BACKWARD COMPATABILITY - An advanced technology frame structure is described herein. The advanced technology frame structure can enhance a first technology frame structure in dimensions of time, frequency, or a combination of time and frequency. A second technology frame structure time division multiplexes second technology subframes with the first technology downlink and uplink subframes. The first technology downlink subframe can be divided into a first technology downlink subframe and one or more second technology downlink subframes. Similarly, the first technology uplink subframe can be divided into a first uplink subframe and one or more second technology uplink subframes. These principles can be expanded upon and can be applied in many communication systems. | 06-07-2012 |
20140161098 | ADVANCED TECHNOLOGY FRAME STRUCTURE WITH BACKWARD COMPATIBILITY - An advanced technology frame structure is described herein. The advanced technology frame structure can enhance a first technology frame structure in dimensions of time, frequency, or a combination of time and frequency. A second technology frame structure time division multiplexes second technology subframes with the first technology downlink and uplink subframes. The first technology downlink subframe can be divided into a first technology downlink subframe and one or more second technology downlink subframes. Similarly, the first technology uplink subframe can be divided into a first uplink subframe and one or more second technology uplink subframes. These principles can be expanded upon and can be applied in many communication systems. | 06-12-2014 |
Patent application number | Description | Published |
20100138235 | METHOD, SYSTEM, AND APPARATUS FOR CLINICAL TRIAL MANAGEMENT OVER A COMMUNICATIONS NETWORK - A centralized, online clinical study system configured to coordinate aspects of a clinical study can include a training module configured to evaluate whether users have completed training for selected workflows for the clinical study that are available from the clinical study system, and to provide training to registered users for the selected workflows. The system also can include a financial engine configured to determine when a participating site meets or exceeds a milestone of the clinical study and to initiate a payment to the participating site. Further, the system can include a module configured to receive and verify clinical research data and to designate the verified clinical research data as official source data for the clinical study. | 06-03-2010 |
20120004927 | METHOD, SYSTEM, AND APPARATUS FOR CLINICAL TRIAL MANAGEMENT OVER A COMMUNICATIONS NETWORK - A centralized, online clinical study system configured to coordinate aspects of a clinical study can include a training module configured to evaluate whether users have completed training for selected workflows for the clinical study that are available from the clinical study system, and to provide training to registered users for the selected workflows. The system also can include a financial engine configured to determine when a participating site meets or exceeds a milestone of the clinical study and to initiate a payment to the participating site. Further, the system can include a module configured to receive and verify clinical research data and to designate the verified clinical research data as official source data for the clinical study. | 01-05-2012 |
20130080186 | Method, System, And Apparatus For Clinical Trial Management Over A Communications Network - A centralized, online clinical study system configured to coordinate aspects of a clinical study can include a training module configured to evaluate whether users have completed training for selected workflows for the clinical study that are available from the clinical study system, and to provide training to registered users for the selected workflows. The system also can include a financial engine configured to determine when a participating site meets or exceeds a milestone of the clinical study and to initiate a payment to the participating site. Further, the system can include a module configured to receive and verify clinical research data and to designate the verified clinical research data as official source data for the clinical study. | 03-28-2013 |
Patent application number | Description | Published |
20120107086 | MOTOR ASSISTED FINE PITCH STARTUP RAM AIR TURBINE - A startup assistance apparatus for a fine pitch Ram Air Turbine (RAT) is provided and includes a generator to provide motive power to the RAT when operating in a first mode and to generate electricity from RAT operation when operating in a second mode and a control unit, including a speed sensing unit configured to sense an operating condition of the generator and a controller operably coupled to the generator and configured to control the generator to operate in the first or the second mode based on the sensed operating condition. | 05-03-2012 |
20120245746 | Automatic Ram Air Turbine Deployment - A method of deploying a ram air turbine for an aircraft only during flight that deploys the ram air turbine only when a predetermined number of aeronautical power generation contactor signals are in an engaged state, an external power generation contactor is in a disengaged state, wheels for the aircraft are in an airborne state and all of multiple primary electric buses are in a fault state that represents electric potential below a predetermined level. | 09-27-2012 |
20120280499 | Generator Frequency Controlled Load Shifting - In a power generation system that includes a ram air turbine that drives an electric generator and at least one electric bus that couples alternating current electric power from the electric generator to at least one electric load, a method of maintaining the speed of the ram air turbine within a desired range of speeds that comprises the step of uncoupling the at least one electric bus from the electric generator when the frequency of the alternating current falls under a desired minimum frequency. | 11-08-2012 |
20120328436 | ELECTROMECHANICAL ACTUATOR DRIVEN GOVERNOR FOR RAM AIR TURBINE - A ram air turbine governor includes a hub carrying multiple turbine blades. A sensor is configured to detect a parameter. A counterweight is coupled to at least one turbine blade and is configured to provide an input to the turbine blade in response to a centrifugal force to move the turbine blade from a first pitch position to a second pitch position. An electromechanical actuator is operatively coupled to the counterweight. A controller is in communication with the mechanical actuator and the sensor. The controller is configured to command the electromechanical actuator and move the turbine blade from the second pitch position to a third pitch position in response to the detected parameter. | 12-27-2012 |
20130214589 | RAM AIR TURBINE SMOKE ISOLATION - An electrical power generation and distribution system includes a RAM air turbine a first direct current essential bus, a second direct current essential bus, a third direct current essential bus, a first contactor disposed between the first and third direct current essential buses, a second contactor disposed between the second and third direct current essential bus, a third contactor disposed between the RAM air turbine and the third direct current essential bus, a RAM air turbine smoke isolation system, including a first drive circuit coupled to the first contactor, a second drive circuit coupled to the second contactor, a third drive circuit coupled to the third contactor and a transfer inhibit switch coupled to the first, second and third drive circuits. | 08-22-2013 |
Patent application number | Description | Published |
20100018969 | PACKAGING FOR FOOD PRODUCTS - The invention relates to packaging for food products, particularly for baked goods such as muffins, cookies, pastries, cupcakes, breads or the like, wherein a container comprises a base or article-receiving portion, and a lid portion that is hinged to the base or article-receiving portion. Both portions have side flanges, wherein the flanges are selectively connected to one another by a fastener system to close the article-receiving portion with the lid portion. The article-receiving portion is formed to conform to and house a single-serving baked food product. The base portion may also have at least one stability member extending therefrom to provide stability of the base portion on a surface. A package of a plurality of containers may be provided, with each individual container being selectively detachable from the package. In an example, the individual containers may be attached to one another by micro perforations, such that upon detachment of an individual container, the connecting portion is smooth and does not have any sharp edges or protrusions which could harm a consumer. | 01-28-2010 |
20130178312 | SYSTEM AND METHODS FOR INDICATING A REFEREE PENALTY FLAG - There is provided systems and methods for enhancing the viewing enjoyment by spectators of a sports game conducted on a playing between two teams of opposing players, and in which at least one referee is present for the purpose of observing any infractions of rules of the game and indicating such an infraction and which team committed the infraction. The systems and methods may include automatic detection of a called penalty and which team is called for the penalty. The systems and methods may also use transmitters which are activated whenever a predetermined event, such as a penalty, is called, and receivers disposed around the playing field to detect that a penalty was called and on which team the call was made. An indication of the rules infraction and the team committing the infraction may then be displayed or communicated to viewers immediately. | 07-11-2013 |
Patent application number | Description | Published |
20110141251 | Method and System for Segmenting Moving Objects from Images Using Foreground Extraction - A set of images is acquired of a scene by a camera. The scene includes a moving object, and a relative difference of a motion of the camera and a motion of the object is substantially zero. Statistical properties of pixels in the images are determined, and a statistical method is applied to the statistical properties to identify pixels corresponding to the object. | 06-16-2011 |
20110234590 | Method for Synthetically Relighting Images of Objects - An image of an object from a known object class is synthesized by first obtaining reflectance fields for various training objects from the object class. A reflectance field model is defined for the object class using a combination of the reflectance fields of the training objects. The parameters of the reflectance field model are optimized to estimate a particular reflectance field of a particular object from the object class given one or more input images of the particular object. The particular reflectance field is fitted to the particular object, and then the new image of the particular object is synthesized by changing the illumination parameters of the particular fitted reflectance field model after the fitting. | 09-29-2011 |
20110276307 | Method and System for Registering an Object with a Probe Using Entropy-Based Motion Selection and Rao-Blackwellized Particle Filtering - A probe is registered with an object by probing the object with the probe at multiple poses, wherein each pose of the probe includes a location and an orientation. A probability distribution of a current location of the probe is represented by a set of particles, and a probability distribution of a current orientation of the probe is represented by a Gaussian distribution for each particle conditioned on the current location. A set of candidate motions is chosen, and for each candidate motion, an expected uncertainty based on the set of particles is determined. The candidate motion with a least expected uncertainty is selected as a next motion of the probe, the probe is moved according to the next motion, and the set of particles is updated using the next pose of the probe. | 11-10-2011 |
20130004028 | Method for Filtering Using Block-Gabor Filters for Determining Descriptors for Images - A Gabor filter is approximated as a block-Gabor filter. The Gabor filter is represented by a matrix of numbers in which each number is a sample derived from a continuous Gabor function. The block-Gabor filter is partitioned into a set of blocks. Identical filter values are assigned to all the pixels in any particular block based on the Gabor filter. Then, a feature can be extracted from an image by filtering the image with a set of the block-Gabor filters to obtain a corresponding set of filtered images. Each filtered image is partitioned into regions of pixels. For each pixel, an N-bit signature is determined. Histograms of the N-bit signatures of the pixels in each region are combined to form the feature. The features of multiple images can be used for face recognition. | 01-03-2013 |
20130243240 | Camera-Based 3D Climate Control - A climate control unit is controlled by constructing background and foreground models of an environment from images acquired of the environment by a camera. The background model represents the environment when unoccupied, and there is one foreground model for each person in the environment. A 2D location of each person in the environment is determined using the background and foreground models. A 3D location of each person is determined using the 2D locations and inferences made from the images. The controlling of the climate control unit is according to the 3D locations. | 09-19-2013 |
20140254863 | Method for Detecting and Tracking Objects in Image Sequences of Scenes Acquired by a Stationary Camera - In a sequence of images of a scene acquired by a stationary camera, objects are detected and tracked by determining a first set of candidate foreground regions according to a background model. A second set of candidate foreground regions is determined. according to a set of foreground models. Then, candidate foreground regions in the first set and the second set are validated to produce a final set of foreground regions in the image that include the objects. | 09-11-2014 |
20140300599 | Method for Factorizing Images of a Scene into Basis Images - A set of nonnegative lighting basis images representing a scene illuminated by a set of stationary light sources is recovered from a set of input images of the scene that were acquired by a stationary camera. Each image is illuminated by a combination of the light sources, and at least two images in the set are illuminated by different combinations. The set of input images is decomposed into the nonnegative lighting basis images and a set of indicator coefficients, wherein each lighting basis image corresponds to an appearance of the scene illuminated by one of the light sources, and wherein each indicator coefficient indicates a contribution of one of the light sources to one of the input images. | 10-09-2014 |
20140300600 | Method for Detecting 3D Geometric Boundaries in Images of Scenes Subject to Varying Lighting - Three-dimensional (3D) geometric boundaries are detected in images of a scene that undergoes varying lighting conditions caused by light sources in different positions, from a set of input images of the scene illuminated by at least two different lighting conditions. The images are aligned, e.g., acquired by a stationary camera, so that pixels at the same location in all of the input images correspond to the same point in the scene. For each location, a patch of corresponding pixels centered at the location is extracted from each input image. For each location, a confidence value that there is a 3D geometric boundary at the location is determined. | 10-09-2014 |