Patent application number | Description | Published |
20100010470 | Nanotube-Reinforced Balloons For Delivering Therapeutic Agents Within Or Beyond The Wall of Blood Vessels, And Methods Of Making And Using Same - A dilatation catheter for delivering a therapeutic agent within a body lumen having a wall with a thickness is provided having a balloon having a flexible wall including a polymer with dispersed nanotubes and pores configured to close below a predefined pressure and to open at or above a predefined pressure. In some embodiments, an actuator is provided to controllably inflate the balloon with a fluid at a pressure sufficient to bring the flexible wall of the balloon into contact with at least a portion of the wall of the body lumen but below the predefined pressure, and to controllably increase the pressure of the fluid within the inflated balloon to at least the predefined pressure at a rate and with a force sufficient to deliver the therapeutic agent from the pores and through at least a portion of the thickness of the wall of the body lumen. | 01-14-2010 |
20100094257 | INVENTORY SPARING CATHETER SYSTEM - Some embodiments relate to a catheter system having a changeable or adjustable working length. The catheter system can comprise a proximal end, a distal end, and a first axial lumen configured to receive a guidewire formed through at least a portion of the catheter body. A first opening can be formed through a portion of the catheter body and be in communication with the first lumen. The sheath can be rotatable, axially movable, or otherwise changeable from at least a first position to a second position, wherein the sheath can substantially cover the first opening in the catheter body in the first position, and can substantially expose the first opening in the catheter body in the second position. | 04-15-2010 |
20100222766 | INVENTORY SPARING CATHETER SYSTEMS AND METHODS - Some embodiments relate to a catheter system having a changeable or adjustable working length. The catheter system can comprise a proximal end, a distal end, and a first axial lumen configured to receive a guidewire formed through at least a portion of the catheter body. A first opening can be formed through a portion of the catheter body and be in communication with the first lumen. The sheath can be rotatable, axially movable, or otherwise changeable from at least a first position to a second position, wherein the sheath can substantially cover the first opening in the catheter body in the first position, and can substantially expose the first opening in the catheter body in the second position. | 09-02-2010 |
20100286658 | INVENTORY SPARING CATHETER SYSTEMS AND METHODS - Some embodiments relate to a catheter system having a changeable or adjustable working length. The catheter system can comprise a proximal end, a distal end, and a first axial lumen configured to receive a guidewire formed through at least a portion of the catheter body. A first opening can be formed through a portion of the catheter body and be in communication with the first lumen. The sheath can be rotatable, axially movable, or otherwise changeable from at least a first position to a second position, wherein the sheath can substantially cover the first opening in the catheter body in the first position, and can substantially expose the first opening in the catheter body in the second position. | 11-11-2010 |
20120016297 | Interventional Devices Including Dilute Nanotube-Polymer Compositions, and Methods of Making and Using Same - Under one aspect, an interventional device includes a balloon having a flexible wall. The flexible wall includes a composition including between 0.005 wt. % and 0.20 wt. % of carbon nanotubes dispersed in a polymer. Under another aspect, a method of making an interventional device includes contacting a plurality of polymer particles with a plurality of nanotubes; extruding the polymer particles and the nanotubes to form a composition comprising the polymer and the nanotubes; and blow-casting the composition into a balloon. | 01-19-2012 |
20120209250 | NANOTUBE-REINFORCED BALLOONS FOR DELIVERING THERAPEUTIC AGENTS WITHIN OR BEYOND THE WALL OF BLOOD VESSELS, AND METHODS OF MAKING AND USING SAME - A dilatation catheter for delivering a therapeutic agent within a body lumen having a wall with a thickness is provided having a balloon having a flexible wall including a polymer with dispersed nanotubes and pores configured to close below a predefined pressure and to open at or above a predefined pressure. In some embodiments, an actuator is provided to controllably inflate the balloon with a fluid at a pressure sufficient to bring the flexible wall of the balloon into contact with at least a portion of the wall of the body lumen but below the predefined pressure, and to controllably increase the pressure of the fluid within the inflated balloon to at least the predefined pressure at a rate and with a force sufficient to deliver the therapeutic agent from the pores and through at least a portion of the thickness of the wall of the body lumen. | 08-16-2012 |
20120209251 | NANOTUBE-REINFORCED BALLOONS FOR DELIVERING THERAPEUTIC AGENTS WITHIN OR BEYOND THE WALL OF BLOOD VESSELS, AND METHODS OF MAKING AND USING SAME - A dilatation catheter for delivering a therapeutic agent within a body lumen having a wall with a thickness is provided having a balloon having a flexible wall including a polymer with dispersed nanotubes and pores configured to close below a predefined pressure and to open at or above a predefined pressure. In some embodiments, an actuator is provided to controllably inflate the balloon with a fluid at a pressure sufficient to bring the flexible wall of the balloon into contact with at least a portion of the wall of the body lumen but below the predefined pressure, and to controllably increase the pressure of the fluid within the inflated balloon to at least the predefined pressure at a rate and with a force sufficient to deliver the therapeutic agent from the pores and through at least a portion of the thickness of the wall of the body lumen. | 08-16-2012 |
20130178926 | Stent Having At Least One Connecting Member Configured to Controllably Sever In Vivo - A stent may include a connector having a first portion, a second portion, and a third portion positioned between the first and second portions. The connector may be configured to interconnect axially adjacent stent segments. The connector may be further configured such that the third portion severs in response to a threshold amount of axial force, axial foreshortening, and/or cyclic loading or fatigue, in order to predispose the severance of one or more pre-configured connectors in a controlled manner to minimize any potential harm to the surrounding vasculature of a patient. | 07-11-2013 |
20130253570 | APPARATUS AND METHODS FOR FILTERING EMBOLI DURING PRECUTANEOUS AORTIC VALVE REPLACEMENT AND REPAIR PROCEDURES WITH FILTRATION SYSTEM COUPLED TO DISTAL END OF SHEATH - Embodiments of the present invention provide apparatus and methods for embolic filtering during percutaneous valve replacement and repair procedures. Under one aspect, an apparatus comprises a sheath and a filter. The sheath has proximal and distal ends and a lumen therebetween. The distal end may be introduced into the aortic arch via the peripheral arteries and ascending aorta, while the proximal end may be disposed outside of the body. The lumen permits percutaneous aortic valve replacement or repair therethrough. The filter has a frame with an inlet and an outlet and an emboli-filtering mesh attached to the frame. The inlet is substantially spans the aortic arch in a region between the aortic valve and the great arteries. The outlet is coupled to the distal end of the sheath without leaving any gaps through which emboli could pass and without obstructing the lumen at the distal end of the sheath. | 09-26-2013 |
20130253571 | APPARATUS AND METHODS FOR FILTERING EMBOLI DURING PERCUTANEOUS AORTIC VALVE REPLACEMENT AND REPAIR PROCEDURES WITH FILTRATION SYSTEM COUPLED IN-SITU TO DISTAL END OF SHEATH - Embodiments of the present invention provide apparatus and methods for embolic filtering during percutaneous valve replacement and repair procedures. Under one aspect, an apparatus comprises a sheath and a filter. The sheath has proximal and distal ends and a lumen therebetween. The distal end may be introduced into the aortic arch via the peripheral arteries and ascending aorta, while the proximal end may be disposed outside of the body. The lumen permits percutaneous aortic valve replacement or repair therethrough. The filter has a frame with an inlet and an outlet and an emboli-filtering mesh attached to the frame. The inlet is substantially spans the aortic arch in a region between the aortic valve and the great arteries. The outlet couples to the distal end of the sheath without leaving any gaps through which emboli could pass and without obstructing the lumen at the distal end of the sheath. | 09-26-2013 |
20130325000 | SYSTEMS FOR TRANSCATHETER ABLATION OF ADVENTITIAL OR PERIVASCULAR TISSUE WHILE PRESERVING MEDIAL AND INTIMAL VASCULAR INTEGRITY THROUGH CONVERGENCE OF ENERGY FROM ONE OR MORE SOURCES, AND METHODS OF MAKING AND USING SAME - Under one aspect of the present invention, a system for performing renal denervation in a patient having an aorta and a renal artery and a branchpoint therebetween includes a flexible catheter comprising a main section, first and second arms, and a bifurcation between the first and second arms, the main section having a proximal end and a distal end, the distal end configured to be disposed in the aorta, the first arm being coupled to the distal end of the main section and configured to be disposed in the renal artery, the second arm being coupled to the distal end of the main section and configured to be disposed in the aorta, the bifurcation between the first and second arms being configured to engage the branchpoint between the aorta and the renal artery. | 12-05-2013 |
20140276921 | RECANALIZATION DEVICE - Catheters for the removal of occlusions in a patient's vasculature. Exemplary catheters use a flexible distal end tube which is capable of coiling irregularly within the occlusion and securing it for removal. | 09-18-2014 |