Maisel
Alan Maisel, Solana Beach, CA US
Patent application number | Description | Published |
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20110021466 | USE OF EPICATECHIN AND DERIVATIVES AND SALTS THEREOF FOR CARDIAC PROTECTION OF ISCHEMIC MYOCARDIUM AND TO AMELIORATE ADVERSE CARDIAC REMODELING - The disclosure provides a method of reducing infarct size in the heart following permanent ischemia or ischemia/reperfusion (IR) event or method for delaying, attenuating or preventing adverse cardiac remodeling comprising administering a drug selected from the group consisting of epicatechin, derivatives thereof and pharmaceutically acceptable salts thereof, wherein the subject is a human or a veterinary animal. Additionally the disclosure provides a method of treating subarachnoid hemorrhage or atrial fibrillation or of enhancing or preserving migration, seeding, proliferation, differentiation and/or survival of stem cells in injured heart tissue comprising administering a drug selected from the group consisting of epicatechin, derivatives thereof and pharmaceutically acceptable salts thereof. The effects of epicatechin administration are sustained over time. | 01-27-2011 |
20130171268 | METHODS AND COMPOSITIONS FOR TREATMENT OF MITOCHONDRIAL TOXICITY - The present invention relates to compositions and methods for prophylactic and/or therapeutic treatment of conditions related to mitochondrial function. In various aspects, the present invention comprises administering one or more compounds selected from the group consisting of epicatechin, an epicatechin derivative, catechin, a catechin derivative, nicorandil, and a nicorandil derivative in an amount effective to ameliorate mitochondrial toxicity caused by administration of a chemical, food, or drug. | 07-04-2013 |
Alan S. Maisel, Solana Beach, CA US
Patent application number | Description | Published |
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20120095063 | METHODS AND COMPOSITIONS FOR TREATMENT OF ISCHEMIC CONDITIONS AND CONDITIONS RELATED TO MITOCHONDRIAL FUNCTION - The present invention relates to compositions and methods for prophylactic and/or therapeutic treatment of conditions related to mitochondrial function. In various aspects, the present invention comprises administering one or more compounds selected from the group consisting of epicatechin, an epicatechin derivative, catechin, a catechin derivative, nicorandil, and a nicorandil derivative in an amount effective to stimulate mitochondrial function in cells. The methods and compositions described herein provide for reducing infarct size in the heart following permanent ischemia or ischemia/reperfusion (IR) event or method for delaying, attenuating or preventing adverse cardiac remodeling, and can assist in prevention of impaired mitochondria biogenesis and thus prevention of the consequences of impaired mitochondrial biogenesis in various diseases and conditions, as well as provide for the active therapy of mitochondrial depletion that may have already occurred. | 04-19-2012 |
Daniela Maisel, Penzberg DE
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20110183864 | METHOD FOR LUNG CANCER EARLY DETECTION AND PROGNOSIS - The present invention provides method for the prognosis or detection of lung cancer, notably for early detection of lung cancer, as well as a kit and a (micro) array suitable for said method. | 07-28-2011 |
20130164219 | CELL-PENETRATING PEPTIDES AND USES THEREOF - The present invention relates to the identification and functional characterization of human cell-penetrating peptides (CPPs) and their use; in particular as transfection vehicles. | 06-27-2013 |
Peter Maisel, Nurnberg DE
Patent application number | Description | Published |
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20120044719 | CONTROL DEVICE FOR THE VOLTAGE- ABSENT SWITCHING OF A SWITCHING ELEMENT OF A VOLTAGE CONVERTER - In a control device ( | 02-23-2012 |
20120087154 | VOLTAGE SUPPLY DEVICE FOR A LOAD - A voltage supply device for a load, in particular for a network, has an energy store that can be connected to connection terminals and a voltage transformer with at least one electronic switch. A reverse polarity protection is in contact with the connection terminals and is designed to convert voltage delivered from the energy store into control voltage for active activation of the electronic switch when the polarity of the voltage is reversed. | 04-12-2012 |