Leitao
Alvaro Augusto Da Costa Leitao, Rio De Janeiro BR
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20090068126 | Composition for surface photoprotection - The molecules capable of absorbing ultraviolet radiation from the cashew nut shell liquid changes are the object of the present invention; it is also described the compositions responsible for protecting the surfaces and chemical processes for the referred molecules production. | 03-12-2009 |
Andre Leitao, Eindhoven NL
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20110123134 | IMAGE CONTRAST ENHANCEMENT - A contrast enhancement method for an image includes extracting at least one sub-band image from the image, comprising detail information at a predetermined spatial scale; determining a first gain value for each pixel, based on pixel values of the image or the at least one sub-band image; determining a second gain value for each pixel; modifying the first gain value for each pixel using the respective second gain value; and generating an enhanced image by applying the modified first gain values to respective pixels of one or more sub-band images and combining the result with the image. Determining the first gain value for each pixel comprises: estimating a dynamic range of the pixel values in a neighbourhood of that pixel; and setting the first gain value in inverse relation to the dynamic range. Determining the second gain value for each pixel comprises: estimating a probability distribution of the pixel values in the neighbourhood; and determining the second gain value based on the amplitude of the peak of the probability distribution. | 05-26-2011 |
Andre Leitao, Den Bosch NL
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20110299769 | IMAGE PROCESSING USING A BILATERAL GRID - A method of processing a digital image. The method comprises: populating ( | 12-08-2011 |
20140241643 | IMAGE PROCESSING USING A BILATERAL GRID - A method of processing a digital image. The method comprises: populating ( | 08-28-2014 |
20150269716 | IMAGE PROCESSING USING A BILATERAL GRID - Methods and systems are provided for processing digital images. An integrated grid, comprising one or more integrated values, may be generated based on processing of an image, with the generating comprising cumulatively integrating at least one value, of a cell in a bilateral grid generated based on the processed image, over the bilateral grid. A modified bilateral grid may then be generated, with generating comprising computing a sum of said at least one value over a portion of said bilateral grid, by using integrated values of said integrated grid corresponding to said portion of said bilateral grid. An output image may be generated based on the modified bilateral grid. | 09-24-2015 |
Andrei Leitao, Sao Carlos BR
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20120302582 | NOVEL BIFUNCTIONAL METNASE/INTNASE INHIBITORS AND RELATED COMPOSITIONS AND METHODS OF TREATMENT OF CANCER - This invention relates to novel cancer treatment compositions and associated therapeutic methods. More particularly, this invention relates in part to small chemical bifunctional inhibitors of DNA replication and repair proteins Metnase and/or Intnase (also termed Gypsy Integrase, Gypsy Integrease-1, Gypsy Retransposon Integrase 1, or GIN-I) that simultaneously damage DNA, and to a therapeutic method that utilizes the inhibitors to increase the effectiveness of cancer treatment protocols, including radiation therapy. In preferred embodiments, compounds, compositions and methods of treatment of the invention are used to treat a patient suffering from leukemia (e.g. acute myeloid leukemia (AML) and related cancers. In certain aspects of such treatments, compounds, compositions and methods of treatment of the invention are administered as a monotherapy (in some cases, to patients who have exhibited resistance to Topo IIalpha inhibitors such as VP-16), or are co-administered with a Topo IIalpha inhibitor or other anti-cancer agents as otherwise described herein or in combination with radiation therapy. | 11-29-2012 |
Andrei Leitao, San Carlos BR
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20150087886 | NOVEL BIFUNCTIONAL METNASE/INTNASE INHIBITORS AND RELATED COMPOSITIONS AND METHODS OF TREATMENT OF CANCER - This invention relates to novel cancer treatment compositions and associated therapeutic methods. More particularly, this invention relates in part to small chemical bifunctional inhibitors of DNA replication and repair proteins Metnase and/or Intnase (also termed Gypsy Integrase, Gypsy Integrease-1, Gypsy Retransposon Integrase 1, or GIN-1) that simultaneously damage DNA, and to a therapeutic method that utilizes the inhibitors to increase the effectiveness of cancer treatment protocols, including radiation therapy. | 03-26-2015 |
Andrei Leitao, Albuquerque, NM US
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20120093917 | METNASE AND INTNASE INHIBITORS AND THEIR USE IN TREATING CANCER - This invention relates to novel cancer treatment compositions and associated therapeutic methods. More particularly, this invention relates in part to small chemical inhibitors of DNA repair proteins (Metnase) and to a therapeutic method that utilizes the inhibitors to increase the effectiveness of cancer treatment protocols. | 04-19-2012 |
Breno H. Leitao, Campinas BR
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20140189173 | Network Efficiency and Power Savings - A mechanism is provided for resource management. A first network interface card in a set of network interface cards receives network data from one or more servers in a set of servers. Responsive to the first network interface card determining that a first threshold has been met indicating that an overload condition is imminent in the first network interface card, the first network interface card sends a resume signal to a second network interface card in the set of network interface cards. Responsive to the first network interface card determining that a second threshold is being met indicating that the overload condition has been met in the first network interface card, the first network interface card delegates the network data that caused the overload condition to be met to the second interface card. | 07-03-2014 |
20140373010 | INTELLIGENT RESOURCE MANAGEMENT FOR VIRTUAL MACHINES - Embodiments of the present invention disclose a method, computer program product, and system for resource management for virtual machines. A computer receives information associated with one or more virtual machines, wherein the received information includes utilization information and workload information associated with each virtual machine of the one or more virtual machines. The computer analyzes the received information associated with the one or more virtual machines. The computer determines virtual machines for resource reallocation, wherein the determined virtual machines include one or more over-utilized virtual machines including at least one over-utilized resource. In another embodiment, the computer determines one or more under-utilized virtual machines, wherein the one or more under-utilized virtual machines include at least one under-utilized resource that corresponds to the determined one or more over-utilized resources. In another embodiment, the computer reallocates resources of the determined virtual machines for resource reallocation. | 12-18-2014 |
20150154141 | Operating A Dual Chipset Network Interface Controller ('NIC') That Includes A High Performance Media Access Control Chipset And A Low Performance Media Access Control Chipset - Operating a dual chipset network interface controller (‘NIC’) that includes a high performance media access control chipset and a low performance media access control chipset, including: determining, by a NIC control module, an amount of network traffic being processed by the NIC; determining, by the NIC control module, whether the amount of network traffic being processed by the NIC exceeds a predetermined threshold; responsive to determining that the amount of network traffic being processed by the NIC exceeds a predetermined threshold, configuring, by the NIC control module, the NIC to utilize the high performance media access control chipset for data communications operations; and responsive to determining that the amount of network traffic being processed by the NIC does not exceed the predetermined threshold, configuring, by the NIC control module, the NIC to utilize the low performance media access control chipset for data communications operations. | 06-04-2015 |
Breno H. Leitao, Araraquara BR
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20140340405 | CROWD MOVEMENT PREDICTION USING OPTICAL FLOW ALGORITHM - The geographical distribution of “crowdable” objects (for example, people with cell phones) is predicted in the form of a pixelated predictive map. The predictive map is based upon an optical flow algorithm, as applied to two, or more, pixelated crowdable object distribution maps, respectively representing distribution at different points in time. | 11-20-2014 |
Breno H. Leitão, Jardim Guanabara Campinas BR
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20140210590 | ENTRY TECHNOLOGY FOR BUILDING AUTOMATION - A computer system accesses identity data providing unique biometric identifications and associated names for respective people. Roles are stored and associating ones of the roles are associated with ones of the people. Rules are stored, wherein each rule is configured to define one of the roles or people and define a condition and an action. The computer system receives from a device at an entryway, biometric data for a person. A named person is indicated for the received biometric data by the identity data accessed by the computer system. The computer system selects a rule corresponding to the identified person or to one of the defined roles for the identified person. The computer system performs the defined action for the selected rule when a current condition satisfies the defined condition for the selected rule. | 07-31-2014 |
Breno Henrique Leitao, Jd Guanabara Campinas BR
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20090063231 | Recommending Waste Reductions and Credit Purchases for Business Units - In an embodiment, revenue loss functions associated with business units are determined and waste credit constraints associated with the business units are received. A recommended waste credit purchase amount and recommended waste credit reduction amounts associated with the business units are calculated by minimizing a sum of the revenue loss functions and a purchase function, subject to the waste credit constraints, a purchase constraint, and a reduction goal constraint. In various embodiments, the recommended waste credit purchase amount and the recommended waste credit reduction amounts are presented, the amount of waste credits specified by the recommended waste credit purchase amount are purchased, and the business units reduce their waste emissions by their respective recommended waste credit reduction amounts. In an embodiment, the minimization is perfumed via a quadratic programming algorithm. | 03-05-2009 |
20150288606 | DATA STREAMING SCHEDULER FOR DUAL CHIPSET ARCHITECTURES THAT INCLUDES A HIGH PERFORAMNCE CHIPSET AND A LOW PERFORMANCE CHIPSET - A dual chipset architecture, a method of operating a scheduler for a dual chipset architecture, and a computer program product for operating a scheduler for a dual chipset architecture. In an embodiment, the dual chipset architecture comprises a high performance processor, a low performance processor, and a scheduler for the processors. The scheduler is provided for determining an expected data traffic flow to the chipset, and for selectively enabling the high and low performance processors, based on this expected data flow, ahead of this expected data flow reaching the chipset. In one embodiment, a specified data traffic indicator is associated with the expected data traffic flow, and the scheduler uses this specified data traffic indicator to determine the expected data traffic flow. In an embodiment, this specified data traffic indicator is a value for a defined window size for the expected data flow. | 10-08-2015 |
20150288608 | DATA STREAMING SCHEDULER FOR DUAL CHIPSET ARCHITECTURES THAT INCLUDES A HIGH PERFORAMNCE CHIPSET AND A LOW PERFORMANCE CHIPSET - A dual chipset architecture, a method of operating a scheduler for a dual chipset architecture, and a computer program product for operating a scheduler for a dual chipset architecture. In an embodiment, the dual chipset architecture comprises a high performance processor, a low performance processor, and a scheduler for the processors. The scheduler is provided for determining an expected data traffic flow to the chipset, and for selectively enabling the high and low performance processors, based on this expected data flow, ahead of this expected data flow reaching the chipset. In one embodiment, a specified data traffic indicator is associated with the expected data traffic flow, and the scheduler uses this specified data traffic indicator to determine the expected data traffic flow. In an embodiment, this specified data traffic indicator is a value for a defined window size for the expected data flow. | 10-08-2015 |
Breno Henrique Leitao, Guanabara Campinas BR
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20130039353 | APPARATUS, METHOD AND PROGRAM PRODUCT FOR SEAMLESS WiFi NETWORK TRANSITIONS - An apparatus, a method and a computer program product for seamless transition between WiFi networks (including in particular WiFi Internet networks) includes within a mobile communication apparatus a mobility layer that is tunneled to a mobility server within a network infrastructure. The mobile communications apparatus includes a wireless network capability, a global positioning system capability, an internal network protocol address and a routing capability. The apparatus, the method and the computer program product also provide that the mobility layer is programmed to sequentially and automatically tunnel to the mobility server at an available geographically defined WiFi network access location predicated upon a global positioning system determined position of the mobile communication apparatus. Embodiments also provide seamless transitions between WiFi networks and cellular networks. | 02-14-2013 |
20140348153 | APPARATUS, METHOD AND PROGRAM PRODUCT FOR SEAMLESS WiFi NETWORK TRANSITIONS - An apparatus and system for seamless transition between WiFi networks (including in particular WiFi Internet networks) includes within a mobile communication apparatus a mobility layer that is tunneled to a mobility server within a network infrastructure. The mobile communications apparatus includes a wireless network capability, a global positioning system capability, an internal network protocol address and a routing capability. The apparatus and system also provide that the mobility layer is programmed to sequentially and automatically tunnel to the mobility server at an available geographically defined WiFi network access location predicated upon a global positioning system determined position of the mobile communication apparatus. Embodiments also provide seamless transitions between WiFi networks and cellular networks. | 11-27-2014 |
20150288587 | EFFICIENT AND SCALABLE METHOD FOR HANDLING RX PACKET ON A MR-IOV ARRAY OF NICS - There are provided a system and a computer program product for operating of network cards in computing systems. The computing systems detect resource utilization of all network cards of physical servers connected via one or more networks. The computing systems monitor network statistics of the network. The computing systems determine an operation of each network card connected to the network according to the monitored network statistics. | 10-08-2015 |
20150288588 | EFFICIENT AND SCALABLE METHOD FOR HANDLING RX PACKET ON A MR-IOV ARRAY OF NICS - There is provided a method for operating of network cards in computing systems. The method comprises: detecting resource utilization of all network cards of computing systems connected via the one or more networks; monitoring network statistics of the network, the monitoring the network statistics including: evaluating whether a resource utilization of each network card connected to the one more networks is larger than a threshold; and determining an operation of each network card connected to the network according to and the detected resource utilization and the monitored network statistics. | 10-08-2015 |
Breno Henrique Leitao, Campinas BR
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20090063211 | Finding a Shortest Waste Credit Path for a Manufacturing Process - In an embodiment, a directed graph is created that includes nodes and directed edges that connect the nodes. The nodes represent components and processes, and the directed edges represent a time order of the components and processes in manufacturing processes. Amounts of waste credits for tail nodes in the directed graph are calculated and stored as weights of entering directed edges of the respective tail nodes. The waste credits represent tradable permits for the components and processes to emit waste as part of the manufacturing processes. A shortest path from a begin node to a final node is found, where the shortest path has a lowest sum of its weights, as compared to the sum of the weights for all other paths that exist in the directed graph from the begin node to the final node. | 03-05-2009 |
20120152298 | RACK MOUNTED THERMOELECTRIC GENERATOR ASSEMBLIES FOR PASSIVELY GENERATING ELECTRICITY WITHIN A DATA CENTER - An apparatus for generating electricity in a computer rack includes a plurality of thermoelectric generator modules secured in a planar assembly having a first side and a second side, wherein each thermoelectric generator module has a first thermally conductive substrate exposed on the first side of the planar assembly and a second thermally conductive substrate exposed on the second side of the planar assembly, and wherein the plurality of thermoelectric generator modules are operatively coupled in a circuit to supply electrical current. The apparatus further comprises a first duct for directing a first fluid stream across the first side of the planar assembly to supply heat to the first thermally conductive substrate, and a second duct for directing a second fluid stream across the second side of the planar assembly to withdraw heat from the second thermally conductive substrate. The planar assembly is secured within a housing between the first and second ducts, wherein the housing has a form factor for being received in a computer rack. | 06-21-2012 |
Catarina Leitao, Lisbon PT
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20150353622 | High Avidity Antigen Recognizing Constructs - The present invention pertains to novel high avidity antigen recognizing constructs, such as antibodies or T cell receptors, which specifically bind to the melanoma associated antigen (MAGE) A1. The constructs of the invention are particularly useful for the diagnosis, prevention or therapy of tumorous diseases which are characterized by the specific expression of the MAGE-A1 antigen. Furthermore provided are nucleic acids, vectors and host cells—such as CD4 or CD8 positive T cells—which encode, comprise or present the antigen recognizing constructs of the invention. The invention thus provides new means for immune therapy, specifically adoptive T cell therapy, for treating cancer. | 12-10-2015 |
Emilia Leitao, Cacem PT
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20100240916 | PROCESS FOR OBTAINING STEROIDAL PHOSPHATE COMPOUNDS - A process for obtaining 21-disodium phosphate pregnane derivative compounds of formula (I), wherein X═R═H or X═F and R=α-CH | 09-23-2010 |
Emilia Perpetua Tavares Leitao, Sao Marcos PT
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20130072698 | Method and Compounds for the Preparation of Monofluoromethylated Biologically Active Organic Compounds - Described are processes for the preparation of monofluoromethylated organic biologically active compounds, such as Fluticasone Propionate and Fluticasone Furoate, in the presence of fluorodecarboxylating reagents such as XeF | 03-21-2013 |
20130225844 | Method for Monofluoromethylation of Organic Substrates to Prepare Biologically Active Organic Compounds - Described is a process for the preparation of monofluoromethylated organic biologically active compounds using monofluoromethylated reagents. Fluticasone Propionate and Fluticasone Furoate can be prepared using, for example, S-monofluoromethyl-S-phenyl-2,3,4,5-tetramethylphenylsulfonium tetrafluoroborate as monofluoromethylating reagent instead of bromofluoromethane. | 08-29-2013 |
20130274460 | Electrophilic Reagents for Monohalomethylation, Their Preparation and Their Uses - The invention provides electrophilic monohalomethylating reagents, methods for their preparation and methods for preparation of monohalomethylated biologically active compounds using such reagents. Typical monohalomethyl groups transferred are FH2C—, CIH2C— and others. The reagents used for transferal of the groups are described by Formulae A-D: wherein: X═F, CI, Br, I, sulfonate esters, phosphate esters or another leaving group; R11=tetrafluoroborates, inflates, halogen, perchlorate, sulfates, phosphates or carbonates The other variables are as defined in the claims. | 10-17-2013 |
20140200341 | Method for the Production of Fluoromethyl Esters of Androstan-17 beta Carboxylic Acids - Described herein are processes for the preparation of monofluoromethylated organic biologically active compounds, starting from protected intermediates and/or reagents to obtain compounds such as fluticasone propionate and fluticasone furoate, in presence of decarboxylating reagents XeF | 07-17-2014 |
Emilia Perpetua Tavares Leitao, S. Marcos PT
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20140171645 | ELECTROPHILIC ALKYLATING REAGENTS, THEIR PREPARATION AND USE - The present invention provides electrophilic alkylating reagents of formula II, wherein is an aryl group, R | 06-19-2014 |
Emilia P.t. Leitao, Lisboa PT
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20130211094 | METHODS OF SYNTHESIZING FACTOR Xa INHIBITORS - Described herein are novel methods of preparing a compound of Formula II or a pharmaceutically acceptable salt thereof. In some embodiments, the method is for preparing betrixaban or a pharmaceutically acceptable salt thereof. Also described are compositions comprising substantially pure betrixaban free base or salt thereof. | 08-15-2013 |
Emília P.t. Leitão, Sao Marcos PT
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20100087658 | METHODS AND INTERMEDIATES FOR SYNTHESIS OF SELECTIVE DPP-IV INHIBITORS - Methods and intermediates for the synthesis of selective inhibitors of dipeptidyl peptidase IV (DPP-IV) are provided. Coupling of a carboxylate salt with a boro-proline derivative provides a protected form of a DPP-IV inhibitor, which may be deblocked to yield the medicinal compound. The carboxylate salt can be a crystalline form of a sodium salt or a dicyclohexylammonium salt. The inhibitor can be used in the treatment of diabetes. | 04-08-2010 |
Emília P.t. Leitão, Sao Marcos PT
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20100087658 | METHODS AND INTERMEDIATES FOR SYNTHESIS OF SELECTIVE DPP-IV INHIBITORS - Methods and intermediates for the synthesis of selective inhibitors of dipeptidyl peptidase IV (DPP-IV) are provided. Coupling of a carboxylate salt with a boro-proline derivative provides a protected form of a DPP-IV inhibitor, which may be deblocked to yield the medicinal compound. The carboxylate salt can be a crystalline form of a sodium salt or a dicyclohexylammonium salt. The inhibitor can be used in the treatment of diabetes. | 04-08-2010 |
Jair Scherrer Leitao, Minas Gerais BR
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20110004990 | TOILET FLUSHING SYSTEM USING COMPRESSED AIR - Toilet Flushing system using compressed air ( | 01-13-2011 |
Paolo Leitao, Braganca PT
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20100292810 | METHOD FOR ORCHESTRATING SERVICES OF A SERVICE-ORIENTED AUTOMATION SYSTEM AND ORCHESTRATION MACHINE - A method for orchestrating services of a service-oriented automation system (SOAS), system components (SMC, LCC) offering services (S, WS) that represent the functionality thereof and requesting services (S) of other system components (SMC, LCC), the behavior of the automation system (SOAS) being controlled by the orchestration of the services (S) of the system components (SMC, LCC) using an orchestration machine (OE), and to an orchestration machine for orchestrating services of a service-oriented automation system (SOAS). In order to achieve an orchestration of services at a device level, it is provided that the orchestration machine (OE) uses high-level Petri nets tailored to service-oriented systems and the orchestration of the services (S) at the device level is performed by interpretation and execution of various HLPN models, which represent the behavior of the automation system (SOAS) and/or the system components (SMC, LCC). | 11-18-2010 |
Paulo Leitao, Braganca PT
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20120029656 | METHOD FOR DEVELOPING A MULTI-AGENT SYSTEM AND MULTI-AGENT SYSTEM - A method for developing a multi-agent system and a multi-agent system, such as an automation and/or production system, including software and/or hardware components, the resources and functions of these components being represented and/or controlled through software agents, each of the software agents having the capability of achieving goals through interaction with the environment and with other agents. In order to increase reconfigurability and flexibility, the resources and functions of the software agents are depicted as services, where each software agent, in order to achieve its own goals, calls up services of other software agents and offers its own resources and functions to other software agents as services. | 02-02-2012 |