Patent application number | Description | Published |
20120115835 | METHODS FOR TREATMENT OF BACTERIAL INFECTIONS - The peptidoglycan layer is a vital component of the bacterial cell wall, which comprises 4→3 and 3→3 transpeptide cross-linkages, the formation of which are catalyzed by D,D- and L,D-transpeptidases, respectively. Methods for the treatment of bacterial infections with agents that inhibit L,D-transpeptidases, either alone or in combination with D,D-transpeptidase inhibitors, are provided herein. Also provided are methods for the treatment of chronic stage tuberculosis with agents that inhibit enzyme with L,D-transpeptidase activity. | 05-10-2012 |
20140342364 | METHODS FOR TREATMENT OF BACTERIAL INFECTIONS - The peptidoglycan layer is a vital component of the bacterial cell wall, which comprises 4→3 and 3→3 transpeptide cross-linkages, the formation of which are catalyzed by D,D- and L,D-transpeptidases, respectively. Methods for the treatment of bacterial infections with agents that inhibit L,D-transpeptidases, either alone or in combination with D,D-transpeptidase inhibitors, are provided herein. Also provided are methods for the treatment of chronic stage tuberculosis with agents that inhibit enzyme with L,D-transpeptidase activity. | 11-20-2014 |
20160047737 | CAPVETTE AND METHOD OF MEASURING OPTICAL DENSITY - A capvette for the optical examination of liquids comprises a cuvette component having a rectangular or square basal surface with four side walls terminating into an aperture, wherein said aperture is in communication with a sealable cap component comprising an opening for fluid passageway from a container into said cuvette component. The capvette and container combination, as a single unit allows reaction of fluid or growth of microorganism and measurement of optical density at desired time intervals. A direct method of measuring optical density comprises simply inserting the cuvette component of the capvette into a spectrophotometer. | 02-18-2016 |