Jones, Cambridgeshire
Alan Henry Jones, Cambridgeshire GB
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20090088962 | APPARATUS FOR AND METHOD OF PROVIDING DATA TO AN EXTERNAL APPLICATION - A method of providing data to an external application is provided. The location and time of an object are periodically recorded to form a record of sightings. The record of sightings is then analysed in accordance with at least one criterion specified by the external application to which the data is to be provided. Lists of sightings from the record meeting the at least one criterion are supplied for use by the external application. | 04-02-2009 |
20100036606 | METHOD OF AND APPARATUS FOR GENERATING ROUTES - A method is provided of generating a plurality of diverse routes from a source to a destination in a weighted directed graph. Such a method may be used for route planning or navigation with the weighted directed graph representing a road network, but may also be used in other applications. A source routing tree is generated from the source to a first set of points of the graph, which may comprise some or all of the points. A destination routing tree is generated from some or all of the points of the graph to the destination. The trees are then combined to form the routes. For example, the sub-routes common to and transverses in the same direction by the source and destination trees may be selected. The sub routes may then be formed into the routes by extending each sub-route as necessary to the source and destination along the source and destination trees. | 02-11-2010 |
Aled Wynne Jones, Cambridgeshire GB
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20120233517 | Data Processing Apparatus and Method - A process for generating a number representative of an analogue data source (ADS) in which during enrolment a distinctive characteristic of the ADS is measured to obtain physical data (PD). Part of the PD is used to generate a physical value (PV) representative of the ADS. An error correction algorithm (ECA) is applied to the PV to generate error correction data (ECD), which is transformed, using another part of the PD, to generate transform data. During subsequent regeneration of the PV, the distinctive characteristic is re-measured to generate a new set of PD, and a PV is generated using the same part of the PD physical data as was used during enrolment. ECD is generated by transforming the transform data, using the same part of the PD as was used to transform the ECD during enrolment. The ECA uses the regenerated ECD to correct errors in the PV representative of the ADS. | 09-13-2012 |
Daniel Brian Jones, Cambridgeshire GB
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20080281085 | Methods And Kits For Folding Proteins - The invention relates to methods for folding protein comprising providing an aqueous solution of a protein in non-native conformation and a linear or branched sugar polymer comprising three or more saccharide units, or a derivative thereof at a concentration suitable to permit folding of the protein and incubating the solution to permit folding of the protein. | 11-13-2008 |
20090298185 | Protein Detection Reagents and Methods with Dyes and Dextrins - The invention provides reagents, methods and kits for detection of proteins and quantitative determination of protein concentration. The reagents comprise a protein-complexing dye, such as a Coomassie dye and one or more dextrins, for the elimination of interference caused by detergents. | 12-03-2009 |
Nicholas John Jones, Cambridgeshire GB
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20130070581 | Controlling Data Transmission - A method of controlling data transmission at a transmitter, the transmitter comprising a link controller that reads data from a buffer for transmission, the transmitter operating according to a protocol in which it is mandatory for the link controller to retransmit a packet until that packet is acknowledged, the method including, at the link controller: transmitting a data packet, the payload of the data packet comprising the first data read from the buffer; determining to retransmit the data packet due to lack of receipt of an acknowledgment that the data packet was received; determining whether the first data in the buffer is still timely; and if the first data in the buffer is not still timely, deleting the first data from the buffer and replacing it with second data, and retransmitting the data packet wherein the payload of the retransmitted data packet comprises the second data read from the buffer. | 03-21-2013 |
Philip C. Jones, Cambridgeshire GB
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20100047237 | PREVENTION OF AGGREGATION OF IMMUNOGLOBULIN LIGHT OR HEAVY CHAINS - The present invention provides an inhibitor of the aggregation of immunoglobulin chains (or immunoglobulin V | 02-25-2010 |
Robert Hughes Jones, Cambridgeshire GB
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20130186203 | Sensor Configuration - A sensing unit includes four uniaxial sensors each capable of detecting a movement component along a respective axis having a respective orientation and arranged such that the angles between any two of said respective orientations of said respective axes are substantially equal, wherein the uniaxial sensors are arranged such that in use the respective axes are at substantially the same angle to the vertical direction and the horizontal direction. | 07-25-2013 |
Timothy Jones, Cambridgeshire GB
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20100168454 | CATALYTIC HYDROGENATION - Catalytic hydrogenation of a double bond, notably a C═C or C═N double bond, is carried out using a homogenous catalyst which is a complex of rhodium or other transition metal containing at least one ligand which is a nitrogenous organic base. Preferably the complex is phosphorus-free and the ligand is a bicyclic base having formula | 07-01-2010 |
20120059198 | DERIVATISATION OF CARBON - A molecular species is covalently attached to elemental carbon by exposing the carbon to a reaction mixture containing a strong base and a compound of the formula (I) or (II) in which X denotes a covalently attached atom or group capable of forming an X | 03-08-2012 |
Timothy D. Jones, Cambridgeshire GB
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20110271358 | HUMAN ANTI-PD-1, PD-L1, AND PD-L2 ANTIBODIES AND USES THEREFOR - The present invention is based, in part, on the identification of novel human anti-PD-1, PD-L1, and PD-L2 antibodies. Accordingly, the invention relates to compositions and methods for diagnosing, prognosing, and treating conditions that would benefit from modulating PD-1, PD-L1, and/or PD-L2 activity (e.g., persistent infectious diseases, autoimmune diseases, asthma, transplant rejection, inflammatory disorders and tumors) using the novel human anti-PD-1, PD-L1, and PD-L2 antibodies described herein. | 11-03-2011 |
20130291136 | HUMAN ANTI-PD-1, PD-L1, AND PD-L2 ANTIBODIES AND USES THEREFOR - The present invention is based, in part, on the identification of novel human anti-PD-1, PD-L1, and PD-L2 antibodies. Accordingly, the invention relates to compositions and methods for diagnosing, prognosing, and treating conditions that would benefit from modulating PD-1, PD-L1, and/or PD-L2 activity (e.g., persistent infectious diseases, autoimmune diseases, asthma, transplant rejection, inflammatory disorders and tumors) using the novel human anti-PD-1, PD-L1, and PD-L2 antibodies described herein. | 10-31-2013 |
Timothy David Jones, Cambridgeshire GB
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20090196880 | Cancer treatment using humanized antibodies that bind to EphB4 - In certain embodiments, this application provides humanized antibodies that bind to the EphB4 protein as well as uses of the antibodies for therapeutic purposes. | 08-06-2009 |
20130136735 | HUMANIZED ANTIBODIES TO iNKT - Methods of treatment to suppress an immune response are provided. The method comprises administering to a subject in need of treatment a naked blocking antibody that binds selectively iNKT cells in an amount effective to suppress the subject's iNKT cell function. Compositions comprising, an isolated, humanized antibody that binds selectively iNKT cells are also provided. | 05-30-2013 |
Timothy G.j. Jones, Cambridgeshire GB
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20100163430 | EROSION AND WEAR RESISTANT SONOELECTROCHEMICAL PROBE - The present invention, in one set of embodiments, provides methods and systems for integrating conducting diamond electrodes into a high power acoustic resonator. More specifically, but not by way of limitation, in certain embodiments of the present invention, diamond electrodes may be integrated into a high power acoustic resonator to provide a robust sensing device that may provide for acoustic cleaning of the electrodes and increasing the rate of mass transport to the diamond electrodes. The diamond electrodes may be used as working, reference or counter electrodes or a combination of two or more of such electrodes. In certain aspects, the high power acoustic resonator may include an acoustic horn for focusing acoustic energy and the diamond electrodes may be coupled with the acoustic horn. | 07-01-2010 |
20100315645 | HIGH POWER ACOUSTIC RESONATOR WITH INTEGRATED OPTICAL INTERFACIAL ELEMENTS - An optical element, which may be part of a system for optical analysis of a material in contact with it, is kept clean by means of the vibrations of a high power acoustic resonator. More specifically, but not by way of limitation, in certain embodiments of the present invention, one or more optical interfacial elements may be integrated with a high power acoustic resonator to provide a robust sensing device that may provide for acoustic cleaning of the optical interfacial elements and/or combining optical and acoustic measurements made by the integrated system for analysis purposes. In certain aspects, the high power acoustic resonator may include an acoustic horn for focusing acoustic energy and the optical interfacial elements may be integrated with the acoustic horn. | 12-16-2010 |
20120290208 | METHOD AND APPARATUS FOR MEASURING CARBON DIOXIDE DISSOLVED IN SOLUTION AND WELLBORE MONITORING SYSTEMS BASED THEREON - A sensing apparatus (and corresponding method) for monitoring carbon dioxide dissolved in a liquid solution employs a crystal surrounded in part by a sample chamber such that, in use, the liquid solution is in direct contact with the crystal. | 11-15-2012 |