Patent application number | Description | Published |
20100049173 | RETINAL REGENERATION - A method of retinal regeneration which improves retinal function by reversal of the degradation of the transport properties of Bruch's membrane. The method involves irradiation through the cornea of the eye to the retinal pigmented epithelium by a laser pulse or sequence of laser pulses having a pulse duration in the range of 10 ps to 20 μs and at a wavelength in the range of about 500 nm to 900 nm. The method applies a radiant exposure which results in the damaging or altering of the retinal pigmented epithelium cells in such a manner as to trigger cellular responses which improve the hydraulic conductivity of Bruch's membrane without causing irreversible damage to adjacent retinal structures and layers. | 02-25-2010 |
20100094197 | EYE THERAPY SYSTEM - In a system for stabilizing a pattern of structural changes in corneal fibrils, an eye treatment system causes corneal fibrils of a cornea of an eye to transition from a first structure to a second structure. An application device applies a cross-linking element to the corneal fibrils. An activating device applies an initiating element to the corneal fibrils and activates the cross-linking element. The cross-linking element causes cross-linking in the corneal fibrils to preserve the second structure of the corneal fibrils. Another application device may apply a cross-linking breaker to the corneal fibrils. The cross-linking breaker halts or reverses at least partially the cross-linking in the corneal fibrils. Another activating device applies an initiating element to the corneal fibrils and activates the cross-linking breaker. Advantageously, the cross-linking breaker provides greater control over the amount and progress of cross-linking that occurs in the corneal fibrils. | 04-15-2010 |
20110080558 | DIAGNOSTIC METHOD AND APPARATUS FOR PREDICTING POTENTIAL PRESERVED VISUAL ACUITY - A diagnostic method is disclosed wherein the potential preserved visual acuity in the retina of a patient is determined from the amount of tissue connecting the inner and outer plexiform layers remaining in the retina. | 04-07-2011 |
20110118654 | Eye Therapy - Embodiments apply a cross-linking agent to a region of corneal tissue. The cross-linking agent improves the ability of the corneal tissue to resist undesired structural changes. For example, the cross-linking agent may be Riboflavin or Rose Bengal, and the initiating element may be photoactivating light, such as ultraviolet (UV) light. In these embodiments, the photoactivating light initiates cross-linking activity by irradiating the applied cross-linking agent to release reactive oxygen radicals in the corneal tissue. The cross-linking agent acts as a sensitizer to convert O | 05-19-2011 |
20110118716 | System and Method for Stabilizing Corneal Tissue After Treatment - Systems and methods stabilize corneal tissue after treatment of the corneal tissue. For example, thermokeratoplasty may be applied to the corneal tissue to address disorders associated with abnormal shaping of the cornea. To stabilize the desired structural changes caused by the treatment, embodiments apply ophthalmic formulations that help to inhibit wound healing. Wound healing may occur in response to the application of the treatment and may produce further structural changes that mitigate or alter the desired effects of the treatment. | 05-19-2011 |
20110285836 | Multimodal Ocular Biometric System - A multimodal biometric identification system captures and processes images of both the iris and the retina for biometric identification. Another multimodal ocular system captures and processes images of the iris and/or the from both eyes of a subject. Biometrics based on data provided by these systems are more accurate and robust than using biometrics that include data from only the iris or only the retina from a single eye. An exemplary embodiment emits photons to the iris and the retina of both eyes, an iris image sensor that captures an image of the iris when the iris reflects the emitted light, a retina image sensor that captures an image of the retina when the retina reflects the emitted light, and a controller that controls the iris and the retina illumination sources, where the captured image of the iris and the captured image of the retina contain biometric data. | 11-24-2011 |
20110288466 | SYSTEMS AND METHODS FOR ACTIVATING CROSS-LINKING IN AN EYE - Devices and approaches for activating cross-linking within at least one eye component of an eye to stabilize and strengthen corneal tissue or other tissues of the eye. Cross-linking is activated within the at least one eye component by conveying a cross-linking agent to regions of the at least one eye component and then activating the cross-linking agent by delivering an initiating element to the at least one eye component. Approaches disclosed herein allow for precisely controlling the three dimensional region of strengthened tissue by conveying the cross-linking agent to regions of the at least one eye component. Approaches allow for conveying the cross-linking agent to a depth below the corneal surface such that cross-linking is activated below the corneal surface. | 11-24-2011 |
20120215155 | CONTROLLED CROSS-LINKING INITIATION AND CORNEAL TOPOGRAPHY FEEDBACK SYSTEMS FOR DIRECTING CROSS-LINKING - Devices and approaches for activating cross-linking within corneal tissue to stabilize and strengthen the corneal tissue following an eye therapy treatment. A feedback system is provided to acquire measurements and pass feedback information to a controller. The feedback system may include an interferometer system, a corneal polarimetry system, or other configurations for monitoring cross-linking activity within the cornea. The controller is adapted to analyze the feedback information and adjust treatment to the eye based on the information. Aspects of the feedback system may also be used to monitor and diagnose features of the eye. Methods of activating cross-linking according to information provided by a feedback system in order to improve accuracy and safety of a cross-linking therapy are also provided. | 08-23-2012 |
20120289886 | CONTROLLED APPLICATION OF CROSS-LINKING AGENT - Devices and approaches for activating cross-linking within at least one eye component of an eye to stabilize and strengthen corneal tissue or other tissues of the eye. Cross-linking is activated within the at least one eye component by conveying a cross-linking agent to regions of the at least one eye component and then activating the cross-linking agent by delivering an initiating element to the at least one eye component. Approaches disclosed herein allow for precisely controlling the three dimensional region of strengthened tissue by conveying the cross-linking agent to regions of the at least one eye component. Approaches allow for conveying the cross-linking agent to a depth below the corneal surface such that cross-linking is activated below the corneal surface. | 11-15-2012 |
20130141560 | MULTIMODAL OCULAR BIOMETRIC SYSTEM - A multimodal biometric identification system captures and processes images of both the iris and the retina for biometric identification. Another multimodal ocular system captures and processes images of the iris and/or the from both eyes of a subject. Biometrics based on data provided by these systems are more accurate and robust than using biometrics that include data from only the iris or only the retina from a single eye. An exemplary embodiment emits photons to the iris and the retina of both eyes, an iris image sensor that captures an image of the iris when the iris reflects the emitted light, a retina image sensor that captures an image of the retina when the retina reflects the emitted light, and a controller that controls the iris and the retina illumination sources, where the captured image of the iris and the captured image of the retina contain biometric data. | 06-06-2013 |
20140024997 | Eye Therapy System - Embodiments apply a cross-linking agent to a region of corneal tissue. The cross-linking agent improves the ability of the corneal tissue to resist undesired structural changes. For example, the cross-linking agent may be Riboflavin or Rose Bengal, and the initiating element may be photoactivating light, such as ultraviolet (UV) light. In these embodiments, the photoactivating light initiates cross-linking activity by irradiating the applied cross-linking agent to release reactive oxygen radicals in the corneal tissue. The cross-linking agent acts as a sensitizer to convert O | 01-23-2014 |
20150025440 | Eye Therapy System - Embodiments apply a cross-linking agent to a region of corneal tissue. The cross-linking agent improves the ability of the corneal tissue to resist undesired structural changes. For example, the cross-linking agent may be Riboflavin or Rose Bengal, and the initiating element may be photoactivating light, such as ultraviolet (UV) light. In these embodiments, the photoactivating light initiates cross-linking activity by irradiating the applied cross-linking agent to release reactive oxygen radicals in the corneal tissue. The cross-linking agent acts as a sensitizer to convert O | 01-22-2015 |
Patent application number | Description | Published |
20110135712 | Biologically Active Taxane Analogs And Methods Of Treatment By Oral Administration - The present invention relates to a novel chemical compound of formula S-(1): | 06-09-2011 |
20110318334 | TAXANE ANALOGS FOR THE TREATMENT OF BRAIN CANCER - Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubles at G2-M interface during mitosis but is not a substrate for MDR protein. In particular, the present application relates to the use of an orally effective abeo-taxane, alone or in combination with temozolomide or bevacizumab, for the treatment of brain cancer. | 12-29-2011 |
20130022668 | Biologically Active Taxane Analogs And Methods Of Treatment By Oral Administration - The present invention relates to a novel chemical compound of formula S-(1): | 01-24-2013 |
20130253044 | TAXANE ANALOGS FOR THE TREATMENT OF BRAIN CANCER - Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubles at G2-M interface during mitosis but is not a substrate for MDR protein. In particular, the present application relates to the use of an orally effective abeo-taxane, alone or in combination with temozolomide or bevacizumab, for the treatment of brain cancer. | 09-26-2013 |
20140023699 | Biologically Active Taxane Analogs and Methods of Treatment by Oral Administration - The present invention relates to a novel chemical compound for use in the treatment of cancer, to compositions containing said compound, methods of manufacture and combinations with other therapeutic agents. | 01-23-2014 |
Patent application number | Description | Published |
20130137743 | AMORPHOUS AND A CRYSTALLINE FORM OF GENZ 112638 HEMITARTRATE AS INHIBITOR OF GLUCOSYLCERAMIDE SYNTHASE - The hemitartrate salt of a compound represented by the following structural formula: (Formula I Hemitartrate), which may be used in pharmaceutical applications, are disclosed. Particular single crystalline forms of the Formula (I) Hemitartrate are characterized by a variety of properties and physical measurements. As well, methods of producing crystalline Formula (I) Hemitartrate, and using it to inhibit glucosylceramide synthase or lowering glycosphingolipid concentrations in subjects to treat a number of diseases, are also discussed. Pharmaceutical compositions are also described. | 05-30-2013 |
20140255381 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS - The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, and for the treatment of cancer. | 09-11-2014 |
20140371460 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS - The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, and for the treatment of cancer. | 12-18-2014 |
20150210681 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS - The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, cystic disease and for the treatment of cancer. | 07-30-2015 |
Patent application number | Description | Published |
20130212278 | CONTROLLING DISTRIBUTION OF RESOURCES IN A NETWORK - Disclosed are various embodiments for controlling distribution of data on a network. In one embodiment, a distribution service receives a request from a user on a client device to access the distribution service. In response, the distribution service determines whether the user and the client device are authorized to access the distribution service. The distribution service identifies which of the resources are accessible to the user and the client device pairing based on a plurality of resource grouping identifiers. The distribution service then determines whether the client device complies with a plurality of distribution rules associated with the identified resources. Upon determining that the client device is compliant, the distribution service transmits the resources related to the compliance. | 08-15-2013 |
20130247144 | Controlling Access to Resources on a Network - Disclosed are various embodiments for controlling access to data on a network. Upon receiving a request comprising a device identifier and at least one user credential to access a remote resource, the request may be authenticated according to at least one compliance policy. If the request is authenticated, a resource credential associated with the remote resource may be provided. | 09-19-2013 |
20130254401 | Controlling Distribution of Resources on a Network - Disclosed are various embodiments for controlling distribution of resources on a network. In one embodiment, a distribution service receives a request from a client device to access resources hosted by a distribution service. In response, the distribution service determines whether the client device is authorized to access the distribution service. The distribution service identifies which of the resources hosted by the distribution service are accessible to the client device based on the resource grouping identifiers associated with the client device. The distribution service determines which distribution rules are associated with the identified resources, the distribution rules including location rules and time rules. The distribution service then transmits the identified resources and identified distribution rules to the client device, where the resources are configured to be exclusively accessible via a containerized client application on the client device while the client device satisfies the distribution rules associated with the resources. | 09-26-2013 |
20130268677 | Shared Resource Watermarking and Management - A method, system and non-transitory computer-readable medium product are provided for shared resource watermarking and management. In the context of a method, a method is provided that includes identifying requests to share resources from a device and identifying a watermark template. The method further includes associating the watermark template with the resources, and authorizing the request to share the resources from the device. | 10-10-2013 |
20130275600 | Resource Watermarking and Management - A method, system and non-transitory computer-readable medium product are provided for resource watermarking and management. In the context of a method, a method is provided that includes identifying resources associated with a device and identifying a watermark template. The method further includes associating the watermark template with the resources, and authorizing the device to perform actions on the resources. | 10-17-2013 |
20130298189 | Functionality Watermarking and Management - A method, system and non-transitory computer-readable medium product are provided for functionality watermarking and management. In the context of a method, a method is provided that includes identifying a request to perform at least one function of a user device and identifying at least one watermark template. The method further includes applying the at least one watermark template to at least one function of the user device and authorizing the request to perform the at least one function of the user device. | 11-07-2013 |
20140026195 | Enterprise-specific Functionality Watermarking and Management - A method, system and non-transitory computer-readable medium product are provided for enterprise-specific functionality watermarking and management. In the context of a method, a method is provided that includes identifying a request to perform at least one function of a user device associated with an enterprise and identifying at least one watermark template associated with an enterprise. The method further includes applying the at least one watermark template associated with the enterprise to at least one function of the user device associated with the enterprise and authorizing the request to perform the at least one function of the user device associated with the enterprise. | 01-23-2014 |
20140040982 | Functionality Watermarking and Management - A method, system and non-transitory computer-readable medium product are provided for functionality watermarking and management. In the context of a method, a method is provided that includes identifying a request to establish an association between a watermark template and a function of at least one user device and determining whether the request to establish the association between the watermark template and the function of the at least one user device is authorized. The method further includes authorizing the request to establish the association between the watermark template and the function of the at least one user device in response to a determination that the request to establish the association between the watermark template and the function of the at least one user device is authorized. | 02-06-2014 |
20140108809 | Functionality Watermarking and Management - A method, system and non-transitory computer-readable medium product are provided for functionality watermarking and management. In the context of a method, a method is provided that includes identifying a request to perform at least one function of a user device and identifying at least one watermark template. The method further includes applying the at least one watermark template to at least one function of the user device and authorizing the request to perform the at least one function of the user device. | 04-17-2014 |
20140157354 | Securing Access to Resources on a Network - Secure access to resources on a network may be provided. Upon receiving a request for at least one resource, a determination may be made as to whether the at least one resource comprises a secure resource. In response to determining that the at least one resource comprises a secure resource, the at least one resource may be retrieved; and at least one security policy may be applied to the at least one resource. | 06-05-2014 |
20140165161 | Enterprise-specific Functionality Watermarking and Management - A method, system and non-transitory computer-readable medium product are provided for enterprise-specific functionality watermarking and management. In the context of a method, a method is provided that includes identifying a request to perform at least one function of a user device associated with an enterprise and identifying at least one watermark template associated with an enterprise. The method further includes applying the at least one watermark template associated with the enterprise to at least one function of the user device associated with the enterprise and authorizing the request to perform the at least one function of the user device associated with the enterprise. | 06-12-2014 |
20140310771 | Time-based Functionality Restrictions - Time-based functionality restrictions may be provided. Periodic scans may be performed to identify requests to perform functions on user devices, to determine whether the functions are compliant with compliance rules associated with the user devices that specify time periods during which the user devices are authorized to perform the functions, and to perform remedial actions if the functions are not compliant with the compliance rules. | 10-16-2014 |
20140310772 | Location-based Functionality Restrictions - Location-based functionality restrictions may be provided. Periodic scans may be performed to identify requests to perform functions on user devices, to determine whether the functions are compliant with compliance rules associated with the user devices that specify location where the user devices are authorized to perform the functions, and to perform remedial actions if the functions are not compliant with the compliance rules. | 10-16-2014 |
20140324649 | Attendance Tracking Via Device Presence - Attendance tracking via mobile devices may be provided. Once a meeting begins, a plurality of mobile devices present at the meeting may be identified. An attendance report for a plurality of attendees at the meeting may be provided based on the presence of each of the identified plurality of mobile devices. | 10-30-2014 |
20140330944 | Time-based Configuration Policy Toggling - Time-based configuration profile toggling may be provided. Configuration profiles associated with user devices may be identified, determinations of whether the user devices are authorized to enable the configuration profiles on the user devices may be made based at least in part on time constraints, and the configuration profiles may be enabled on the user devices if the time constraints are satisfied. | 11-06-2014 |
20140330945 | Location-based Configuration Policy Toggling - Location-based configuration profile toggling may be provided. Configuration profiles associated with user devices may be identified, determinations of whether the user devices are authorized to enable the configuration profiles on the user devices may be made based at least in part on location constraints, and the configuration profiles may be enabled on the user devices if the location constraints are satisfied. | 11-06-2014 |
20140331316 | Functionality Watermarking and Management - A method, system and non-transitory computer-readable medium product are provided for functionality watermarking and management. In the context of a method, a method is provided that includes identifying a request to establish an association between a watermark template and a function of at least one user device and determining whether the request to establish the association between the watermark template and the function of the at least one user device is authorized. The method further includes authorizing the request to establish the association between the watermark template and the function of the at least one user device in response to a determination that the request to establish the association between the watermark template and the function of the at least one user device is authorized. | 11-06-2014 |
20140337925 | Secure Application Leveraging of Web Filter Proxy Services - Secure application leveraging of a filter proxy service may be provided. In response to receiving a request to access a resource, a filter proxy service may be used to determine whether the request to access the resource is approved. If the request to access the resource is approved, the access to the resource may be allowed to continue. | 11-13-2014 |
20150371194 | Attendance Tracking Via Device Presence - Attendance tracking via mobile devices may be provided. Once a meeting begins, a plurality of mobile devices present at the meeting may be identified. An attendance report for a plurality of attendees at the meeting may be provided based on the presence of each of the identified plurality of mobile devices. | 12-24-2015 |