Jayawardena
H. S. N. Jayawardena, Lowell, MA US
Patent application number | Description | Published |
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20130252843 | METHOD OF MAKING AND USING FLUORESCENT-TAGGED NANOPARTICLES AND MICROARRAYS - Disclosed embodiments concern differentiating and classifying one or more targets using a perhalophenylazide-derived nanoparticle probe, or multiple such probes. Particular embodiments concern using statistical analysis to produce score plots illustrating the level of differentiation and/or classification. Also disclosed are methods for making perhalophenylazide-derived nanoparticle probes, individually or by using a microarray technique. Particular embodiments concern methods for using the per halophenylazide-derived nanoparticle probes to diagnose, detect, and/or treat a disease. Kits comprising the perhalophenylazide-derived nanoparticle probes are also disclosed. | 09-26-2013 |
H. Surangi N. Jayawardena, Lowell, MA US
Patent application number | Description | Published |
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20160045612 | FUNCTIONALIZED NANOPARTICLES FOR MEDICAL TREATMENTS - A class of functionalized nanoparticles useful in medical treatments is described. The nanoparticles have an attached carbohydrate that is selected on the basis that a cell to be treated ingests as a consequence of the presence of the carbohydrate. The nanoparticles have an attached chemical that if inside the cell is capable of treating the cell (e.g., curing a disease condition in the cell, killing the cell if it is pathogenic, or improving the health of the cell). The nanoparticle carries the chemical preferentially into the cell because the cell will ingest the carbohydrate, and thereby allows the nanoparticle and the chemical into itself. | 02-18-2016 |
Kalana W. Jayawardena, Lowell, MA US
Patent application number | Description | Published |
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20160045612 | FUNCTIONALIZED NANOPARTICLES FOR MEDICAL TREATMENTS - A class of functionalized nanoparticles useful in medical treatments is described. The nanoparticles have an attached carbohydrate that is selected on the basis that a cell to be treated ingests as a consequence of the presence of the carbohydrate. The nanoparticles have an attached chemical that if inside the cell is capable of treating the cell (e.g., curing a disease condition in the cell, killing the cell if it is pathogenic, or improving the health of the cell). The nanoparticle carries the chemical preferentially into the cell because the cell will ingest the carbohydrate, and thereby allows the nanoparticle and the chemical into itself. | 02-18-2016 |
Tilanthi Jayawardena, Durham, NC US
Patent application number | Description | Published |
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20140011281 | Direct Reprogramming of Cells to Cardiac Myocyte Fate - A method for promoting conversion of cells into cardiomyocytic tissue is carried out by contacting fibrotic tissue (e.g., scar tissue) with a microRNA oligonucleotide or combination of microRNA oligonucleotides. The methods lead to direct reprogramming of fibroblasts to cardiomyocytes or cardiomyoblasts. | 01-09-2014 |