Patent application number | Description | Published |
20080208313 | Drug Coated Stent With Magnesium Topcoat - A method for manufacturing a drug carrying stent includes applying at least a first therapeutic agent to at least an outer portion of a stent framework and applying a first magnesium coating on at least a first portion of the applied first therapeutic agent. | 08-28-2008 |
20100092535 | Nanoporous Drug Delivery System - Disclosed herein are controlled release drug delivery systems. The systems comprise a medical device at least one nonoporous surface, at least one bioactive agent and optionally a biodegradable polymer. The nanoporous surfaces of the medical devices contain nanopores capable of acting as reservoirs for drugs that are controllably released. | 04-15-2010 |
20100211153 | Retractable Drug Delivery System and Method - A system for treating a vascular condition includes a catheter having an inner member and an outer member, the outer member concentrically arranged about the inner member and a retractable drug delivery device disposed at a distal end of the inner member. A coating disposed on at least a portion of an outer surface of the retractable drug delivery device includes at least one therapeutic agent. | 08-19-2010 |
20110263960 | Stent Delivery System for Detecting Wall Apposition of the Stent During Deployment - A stent delivery and apposition detecting system includes at least one electrode pair of dissimilar metals mounted on a balloon of a balloon catheter. The electrode pair forms part of an electrochemical cell, and voltage and current generated from the electrochemical cell enables the system to detect when a stent mounted on the balloon achieves proper wall apposition. As the balloon is exposed to different environments, i.e., blood or tissue having different resistances, the electric potential of the electrochemical cell changes and an alert is generated by a feedback circuit to notify a user that the electrodes are in contact with tissue of the vessel wall. In one embodiment, the feedback circuit may be powered by the electrochemical cell. Multiple sets of electrode pairs may be mounted along the circumference and length of the balloon to detect differential contact between the deployed stent and the vessel wall. | 10-27-2011 |
20130284310 | APPARATUS AND METHODS FOR FILLING A DRUG ELUTING MEDICAL DEVICE VIA CAPILLARY ACTION - Methods and apparatus are disclosed for filling a therapeutic substance or drug within a hollow wire that forms a stent. The stent is placed within a chamber housing a fluid drug formulation. During filling, the chamber is maintained at or near the vapor-liquid equilibrium of the solvent of the fluid drug formulation. To fill the stent, a portion of the stent is placed into contact with the fluid drug formulation until a lumenal space defined by the hollow wire is filled with the fluid drug formulation via capillary action. After filling is complete, the stent is retracted such that the stent is no longer in contact with the fluid drug formulation. The solvent vapor pressure within the chamber is reduced to evaporate a solvent of the fluid drug formulation. A wicking means may control transfer of the fluid drug formulation into the stent. | 10-31-2013 |
20130284311 | APPARATUS AND METHODS FOR FILLING A DRUG ELUTING MEDICAL DEVICE VIA CAPILLARY ACTION - Methods and apparatus are disclosed for filling a therapeutic substance or drug within a hollow wire that forms a stent. The stent is placed within a chamber housing a fluid drug formulation. During filling, the chamber is maintained at or near the vapor-liquid equilibrium of the solvent of the fluid drug formulation. To fill the stent, a portion of the stent is placed into contact with the fluid drug formulation until a lumenal space defined by the hollow wire is filled with the fluid drug formulation via capillary action. After filling is complete, the stent is retracted such that the stent is no longer in contact with the fluid drug formulation. The solvent vapor pressure within the chamber is reduced to evaporate a solvent of the fluid drug formulation. A wicking means may control transfer of the fluid drug formulation into the stent. | 10-31-2013 |
20150245930 | HOLLOW DRUG-FILLED STENT AND METHOD OF FORMING HOLLOW DRUG-FILLED STENT - A stent is formed from a wire having an outer member, a radiopaque member lining at least a portion of the outer member inner surface, and a lumen defined by the outer member inner surface or the radiopaque member inner surface. A substance is disposed in the lumen to be eluted through at least one opening disposed through the outer member to the lumen. The radiopaque member may be substantially continuous along the length of the wire or disposed only along portions of the wire such as crowns. In a method for making the stent, a composite wire including an outer member, a radiopaque intermediate member, and a core member is shaped into a stent pattern and processed to remove the core member and optionally portions of the radiopaque intermediate member, without damaging the outer member. | 09-03-2015 |
20160120666 | Apparatus and Methods for Filling a Drug Eluting Medical Device Via Capillary Action - Methods and apparatus are disclosed for filling a therapeutic substance or drug within a hollow wire that forms a stent. The stent is placed within a chamber housing a fluid drug formulation. During filling, the chamber is maintained at or near the vapor-liquid equilibrium of the solvent of the fluid drug formulation. To fill the stent, a portion of the stent is placed into contact with the fluid drug formulation until a lumenal space defined by the hollow wire is filled with the fluid drug formulation via capillary action. After filling is complete, the stent is retracted such that the stent is no longer in contact with the fluid drug formulation. The solvent vapor pressure within the chamber is reduced to evaporate a solvent of the fluid drug formulation. A wicking means may control transfer of the fluid drug formulation into the stent. | 05-05-2016 |