Patent application number | Description | Published |
20090222012 | CANINE ELBOW REPAIR AND INSTRUMENTATION - Methods and instrumentation for arthroscopic elbow surgery which include a humeral component. The humeral component is installed in a trough formed in the humeral condyle. The trough may be formed by using a plurality of drill pins and a plurality of corresponding cutters (and optionally a template). The two drill pins are passed through the template and drilled into the humerus, and cutters are advanced over the corresponding drill pins to form the trough. The humeral component may be employed in conjunction with an ulnar implant. | 09-03-2009 |
20100036492 | OSTEOCHONDRAL IMPLANTS, ARTHROPLASTY METHODS, DEVICES, AND SYSTEMS - Implants for resurfacing or repairing one or more articular cartilage bearing surfaces of a biological organism include an engineered tissue and a biocompatible porous substrate secured to the engineered tissue for attaching the implant to a native bone of the biological organism. The engineered tissue includes a scaffold containing a biocompatible material, and a plurality of living chondrocytes supported by the scaffold. Methods for culturing chondrocytes for incorporation into a biocompatible implant are provided. A bioreactor for producing functional cartilaginous tissue from a cell-seeded scaffold and a system for producing functional cartilaginous tissue are also provided. | 02-11-2010 |
20110118781 | METHOD AND SUTURE-BUTTON CONSTRUCT FOR STABILIZATION OF CRANIAL CRUCIATE LIGAMENT DEFICIENT STIFLE - An apparatus and method for stabilization of a cranial cruciate ligament deficient stifle in canines using a suture-button construct. The method includes the steps of drilling a femoral hole across a distal femur, passing a needle with a pull-through suture strand of a suture-button construct through the femoral hole, and applying a tensile force to the pull-through suture strand and a suture tape or strand of the construct such that a first button of the suture-button construct lies sideways for passage through the femoral hole, advancing the first button through the femoral hole by pulling the pull-through suture strand until the first button exits the femoral hole, drilling a tibial hole and passing the needle with the pull-through suture strand through the tibial hole, applying a tensile force to the pull-through suture strand and the suture tape or strand of the construct such that the first button lies sideways for passage through the tibial hole, flipping the first button to engage the first button against the medial tibial cortex and subsequently cutting and removing the pull-through suture strand, pulling free ends of the suture tape or strand to advance a second button of the suture-button construct and to seat the second button against the femur, and securing the second button against the femur. | 05-19-2011 |
20110218116 | BIOMARKERS OF OSTEOARTHRITIS - Biomarkers, biomarker panels and methods for diagnosing osteoarthritis (OA) are disclosed, using measurement of the expression level of certain polypeptides in a test sample from a subject, including MCP1, IL8, KC, MMP2, MMP3, IL6, MMP1, RANTES, MMP9, IL1B, Apolipoprotein A1, Apolipoprotein E, DCN, CILP and COMP. Related methods for monitoring OA treatment efficacy, diagnostic reagents, and kits are also described. | 09-08-2011 |
20120177615 | TISSUE PRESERVATION SYSTEM - The present invention provides a method and apparatus for tissue, such as an allograft, storage and preservation for extended periods of time at room temperature in a sterile tissue culture chamber. The invention further provides a process for maintaining the sterility of tissue using the apparatus as described. | 07-12-2012 |
20130268082 | CANINE ELBOW REPAIR AND INSTRUMENTATION - Instrumentation and assembly for arthroscopic elbow surgery which includes a humeral component. The humeral component is installed in a trough formed in the humeral condyle. The trough may be formed by using a plurality of drill pins and a plurality of corresponding cutters (and optionally a template). The two drill pins are passed through the template and drilled into the humerus, and cutters are advanced over the corresponding drill pins to form the trough. The humeral component may be employed in conjunction with an ulnar implant. | 10-10-2013 |
20130338792 | IMPLANTATION OF MICRONIZED ALLOGRAFT TISSUE OVER A MICROFRACTURED DEFECT - Techniques, mixtures, mixing and delivery kits, and improved delivery instruments for implantation of micronized allograft tissue over a microfractured defect. Allograft cartilage tissue is delivered over a cartilage defect that has been debrided and microfractured, without the need for a periosteal covering or separate type of patch sewn over the top. The allograft tissue may be any micronized cartilage particulates obtained by various methods, for example, cartilage delivered in its native form, dehydrated via lyophilization, “freeze-dried,” dehydrated via desiccation, or dehydrated by any other method. | 12-19-2013 |
20140091491 | OSTEOCHONDRAL IMPLANTS, ARTHROPLASTY METHODS, DEVICES, AND SYSTEMS - Implants for resurfacing or repairing one or more articular cartilage bearing surfaces of a biological organism include an engineered tissue and a biocompatible porous substrate secured to the engineered tissue for attaching the implant to a native bone of the biological organism. The engineered tissue includes a scaffold containing a biocompatible material, and a plurality of living chondrocytes supported by the scaffold. Methods for culturing chondrocytes for incorporation into a biocompatible implant are provided. A bioreactor for producing functional cartilaginous tissue from a cell-seeded scaffold and a system for producing functional cartilaginous tissue are also provided. | 04-03-2014 |
20140155499 | BIOMARKERS OF OSTEOARTHRITIS - Biomarkers, biomarker panels and methods for diagnosing osteoarthritis (OA) and determining treatment are disclosed, using measurement of the expression level of certain polypeptides in a test sample from a subject, including MCP1, IL8, KC, MMP2, MMP3, Apolipoprotein A1, and Apolipoprotein E. Related methods for monitoring OA treatment efficacy, diagnostic reagents, and kits are also described. | 06-05-2014 |
20140180414 | SYSTEM, APPARATUS, AND METHOD FOR GRAFTING TISSUE - Systems, apparatus, and methods may be adapted for grafting tissue at a tissue site that may include an elongate housing and a plurality of elongate cutting members. The plurality of elongate cutting members may define a cutting surface at a distal end of the elongate housing. The cutting surface may be adapted to contract from a first diameter to a second diameter that is less than the first diameter. The contraction of the cutting surface from the first diameter to the second diameter may define a tapered profile between the first diameter and the second diameter suitable for obtaining a tapered graft. | 06-26-2014 |