Patent application number | Description | Published |
20080267902 | BLOOD PRODUCTS WITH BINDING AGENT - The present invention provides a non-liquid biomaterial that may be used as a surgical sealant, a suture support, a blood flow controller, an adhesion reducing agent, an adhesion preventing agent, a tissue support, a tissue filler, a wound dressing or a combination thereof. The non-liquid biomaterial may comprise a blood derived material such as plasma, platelet poor plasma, platelet rich plasma or a material derived from blood containing tissue aspirate, such as bone marrow aspirate, a protein binding agent and a polymerizing agent. Methods for making and using the non-liquid biomaterial are also provided. | 10-30-2008 |
20100055087 | METHODS AND COMPOSITIONS FOR DELIVERING INTERLEUKIN-1 RECEPTOR ANTAGONIST - Methods and compositions generating and using an interleukin-1 receptor antagonist (IL-1ra)-rich solution. Methods for generating and isolating interleukin-1 receptor antagonist include incubating adipose tissue and/or adipocytes with polyacrylamide beads to produce interleukin-1 receptor antagonist. The interleukin-1 receptor antagonist is isolated from the polyacrylamide beads to obtain the solution rich in interleukin-1 receptor antagonist. Methods for treating a site of inflammation in a patient include administering to the site of inflammation the solution rich in interleukin-1 receptor antagonist. | 03-04-2010 |
20110052561 | OSTEOLYSIS TREATMENT - Methods and treatments for osteolysis employing interleukin-1 receptor antagonist (IL-1ra). Activating production of interleukin-1 receptor antagonist includes incubating adipose tissue, adipocytes, whole blood, platelet rich plasma, and/or isolated white blood cells with polyacrylamide beads to produce a solution rich in interleukin-1 receptor antagonist. Activating the production of interleukin-1 receptor antagonist includes using an implantable device loaded with adipose tissue, adipocytes, whole blood, platelet rich plasma, and/or isolated white blood cells. Methods for treating osteolysis at the site of an artificial joint in a patient include administering and/or inserting the solution rich in interleukin-1 receptor antagonist and/or the implantable device, respectively. | 03-03-2011 |
20120076750 | FIBRIN BASED GLUE WITH FUNCTIONALIZED HYDROPHILIC POLYMER PROTEIN BINDING AGENT - The present invention provides a non-liquid biomaterial that may be used as a surgical sealant, a suture support, a blood flow controller, an adhesion reducing agent, an adhesion preventing agent, a tissue support, a tissue filler, a wound dressing or a combination thereof. The non-liquid biomaterial may comprise a blood derived material such as plasma, platelet poor plasma, platelet rich plasma or a material derived from blood containing tissue aspirate, such as bone marrow aspirate, a protein binding agent and a polymerizing agent. Methods for making and using the non-liquid biomaterial are also provided. | 03-29-2012 |
20130178425 | METHODS AND COMPOSITIONS FOR DELIVERING INTERLEUKIN-1 RECEPTOR ANTAGONIST - Methods, systems, and compositions related to generating and using a solution rich in interleukin-1 receptor antagonist are provided. Methods include contacting a liquid comprising white blood cells with a solid extraction material and stimulating with an electromagnetic field to activate production of interleukin-1 receptor antagonist. The interleukin-1 receptor antagonist can be separated from the solid extraction material. Methods for treating a site of inflammation in a patient include administering the solution rich in interleukin-1 receptor antagonist to the site of inflammation. | 07-11-2013 |
20140277659 | Systems and Methods for Remote Manufacturing of Medical Devices - A system and method for remote manufacturing of medical devices are provided. The system can be installed at a facility (e.g., at a hospital or other medical facility), and includes a remote manufacturing unit (RMU) that allows for customized, rapid fabrication of medical devices at the medical facility using suitable manufacturing techniques such as three-dimensional (3D) printing, additive manufacturing, subtractive manufacturing, etc. The RMU can communicate with a computer system which presents a healthcare professional with a digital catalog of medical products, and allows the healthcare professional to select and customize a desired device to be manufactured at the facility. | 09-18-2014 |
20150354751 | CLAMP RING SHAPE - A clamp ring includes a generally arced portion. The generally arced portion has a top half and a bottom half each having a guide channel formed therein, the top half and the bottom half each have an exterior portion and an interior portion defining boundaries of the guide channels. The interior portions together have a partially circular cross section with a number of interior reliefs formed therein and the exterior portions together have a partially circular cross section with a number of exterior reliefs formed therein that is greater than zero and equal to or greater than the number of interior reliefs formed in the interior portions. | 12-10-2015 |
20150366601 | IMPACT LOAD-LIMITING SURGICAL IMPACTOR - The present invention provides a surgical impactor that includes an impact head, an impacting portion connected to the impact head and a load-transmitting stem connecting the impacting portion to the impact head. The impact head has an impact surface that can be struck by a tool such as a mallet. The load-transmitting stem includes at least one load-limiting resistor. The load-limiting resistor is configured to lock to the impact head and unlock from the impact head when an overload force is applied to the impact surface of the impact head. | 12-24-2015 |