Hickman
Alison B. Hickman, Washington, DC US
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20150284768 | EUKARYOTIC TRANSPOSASE MUTANTS AND TRANSPOSON END COMPOSITIONS FOR MODIFYING NUCLEIC ACIDS AND METHODS FOR PRODUCTION AND USE IN THE GENERATION OF SEQUENCING LIBRARIES - Novel hyperactive Hermes Transposase mutants and genes encoding them are disclosed. These transposases are easily purified in large quantity after expression in bacteria. The modified Hermes Transposases are soluble and stable and exist as smaller active complexes compared to the native enzyme. The consensus target DNA recognition sequence is the same as the native enzyme and shows minimal insertional sequence bias. These properties are useful in whole genome sequencing applications that involve sample DNA preparation requiring simultaneous fragmentation and attachment of custom sequences to the ends of the fragments. Methods and compositions using these transposases in fragmentation and 5′ end-tagging are also disclosed. | 10-08-2015 |
Charles Hickman, Bristol GB
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20140164338 | ORGANIZING INFORMATION DIRECTORIES - Building an information directory can include sending source data to an information extractor, wherein the source data includes first source metadata, extracting second source metadata using the source data, using the information extractor, merging the first source metadata and the second source metadata into third source metadata, and organizing the third source metadata in the information directory. | 06-12-2014 |
Craig J. Hickman, Overland Park, KS US
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20150068708 | AIR-TO-AIR HEAT EXCHANGER BYPASS FOR WET COOLING TOWER APPARATUS AND METHOD - A cooling tower having an evaporative media along with a liquid distribution system that distributes hot liquid over the evaporative media. The cooling tower includes a pair of heat exchanger modules that each have a first set of passageways in fluid communication with a first flow duct and a second set of passageways in fluid communication with a second flow duct. The heat exchanger module transfers heat from a first air stream into a second air stream. The cooling tower further includes a first bypass flow path that extends between the first heat exchanger module and the second heat exchanger module whereby a bypass door regulates airflow there through. | 03-12-2015 |
20150069643 | AIR-TO-AIR HEAT EXCHANGER BYPASS FOR WET COOLING TOWER APPARATUS AND METHOD - A cooling tower having an evaporative media along with a liquid distribution system that distributes hot liquid over the evaporative media. The cooling tower includes a pair of heat exchanger modules that each have a first set of passageways in fluid communication with a first flow duct and a second set of passageways in fluid communication with a second flow duct. The heat exchanger module transfers heat from a first air stream into a second air stream. The cooling tower further includes a first bypass flow path that extends between the first heat exchanger module and the second heat exchanger module whereby a bypass door regulates airflow there through. | 03-12-2015 |
David Hickman, La Tour De Treme CH
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20100098707 | Monoclonal Antibody - The present invention is related to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with amyloid or amyloid-like proteins including amyloidosis, a group of disorders and abnormalities associated with amyloid protein such as Alzheimer's disease. The present invention provides novel methods and compositions comprising highly specific and highly effective antibodies having the ability to specifically recognize and bind to specific epitopes from a range of β-amyloid proteins. The antibodies enabled by the teaching of the present invention are particularly useful for the treatment of diseases and disorders which are caused by or associated with amyloid or amyloid-like proteins including amyloidosis, a group of diseases and disorders associated with amyloid plaque formation including secondary amyloidosis and age-related amyloidosis including, but not limited to, neurological disorders such as Alzheimer's Disease (AD). | 04-22-2010 |
20100297132 | Monoclonal antibody - The present invention is related to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with amyloid or amyloid-like proteins including amyloidosis, a group of disorders and abnormalities associated with amyloid protein such as Alzheimer's disease. The present invention provides novel methods and compositions comprising highly specific and highly effective antibodies having the ability to specifically recognize and bind to specific epitopes from a range of β-amyloid proteins. The antibodies enabled by the teaching of the present invention are particularly useful for the treatment of diseases and disorders which are caused by or associated with amyloid or amyloid-like proteins including amyloidosis, a group of diseases and disorders associated with amyloid plaque formation including secondary amyloidosis and age-related amyloidosis including, but not limited to, neurological disorders such as Alzheimer's Disease (AD). | 11-25-2010 |
20110070613 | Monoclonal Antibody - The present invention is related to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with amyloid or amyloid-like proteins including amyloidosis, a group of disorders and abnormalities associated with amyloid protein such as Alzheimer's disease. The present invention provides novel methods and compositions comprising highly specific and highly effective antibodies having the ability to specifically recognize and bind to specific epitopes from a range of β-amyloid proteins. The antibodies enabled by the teaching of the present invention are particularly useful for the treatment of diseases and disorders which are caused by or associated with amyloid or amyloid-like proteins including amyloidosis, a group of diseases and disorders associated with amyloid plaque formation including secondary amyloidosis and age-related amyloidosis including, but not limited to, neurological disorders such as Alzheimer's Disease (AD). | 03-24-2011 |
David Hickman, Saint-Sulpice CH
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20130224287 | Liposome-Based Construct Comprising a Peptide Modified Through Hydrophobic Moieties - The present invention relates to method for preparing liposome-based constructs comprising a peptide, particularly an antigenic peptide, of interest modified through hydrophobic moieties reconstituted in liposomes and to the antigenic constructs obtained with said method. The invention further relates to the use of said constructs for the therapeutic and diagnostic use in the treatment of diseases and disorders, which are caused by or associated with proteopathy such as Alzheimer's Disease. | 08-29-2013 |
20130287838 | VACCINE ENGINEERING - The method and constructs disclosed and claimed herein allow to control peptide conformation by modulation of the peptide lipidation pattern, spacer and liposome composition, or via co-administration with small molecules. Accordingly, this technology can be applied to the rational design of liposomal vaccines and for the generation of safer and more efficacious therapies for a range of human disease, in particular those based on misfolded proteins. | 10-31-2013 |
20150183857 | METHODS AND COMPOSITIONS COMPRISING SUPRAMOLECULAR CONSTRUCTS - The present invention comprises novel compositions and methods for eliciting high immune responses, of great specificity yielding conformationally sensitive antibodies. These antibodies recognize specific epitopes on a wide variety of antigens including but not limited to, amyloid protein, prion protein, P | 07-02-2015 |
David Hickman, Strasbourg FR
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20120045463 | Methods and compositions comprising supramolecular constructs - The present invention comprises novel compositions and methods for eliciting high immune responses, of great specifity yielding conformationally sensitive antibodies. These antibodies recognize specific epitopes on a wide variety of antigens including but not limited to, amyloid protein, prion protein, P | 02-23-2012 |
David A. Hickman, Winterville, NC US
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20160122077 | PALLET TRUCK WITH INTEGRATED HALF-SIZE PALLET SUPPORT - The present application discloses a pallet truck backrest assembly for handling half-size pallets. A first half-size pallet support is pivotally coupled to a backrest of the backrest assembly at a first height and a second half-size pallet support is pivotally coupled to the backrest at a second height with the second height being less than the first height. The half-size pallet supports pivot between first positions against the backrest and second positions extending over the forks of the pallet truck to accommodate half-size pallets. | 05-05-2016 |
David L. Hickman, Mobile, AL US
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20150144374 | VARYING RADIAL ORIENTATION OF A POWER CABLE ALONG THE LENGTH OF AN UMBILICAL - A power triad of an umbilical may be rotated during multiple transition lengths to position each power cable of the power triad equally at radial orientation over the length of the umbilical. A first portion of the umbilical includes the triad in a first radial orientation, a second portion of the umbilical includes the triad in a second radial orientation, and a third portion of the umbilical includes the triad in a third radial orientation. The triad is rotated a first one hundred twenty degrees from the first radial orientation to the second radial orientation during a first transition length. The triad is rotated a second one hundred twenty degrees from the second radial orientation to the third radial orientation during a second transition length. The use of three radial orientations along the length of the umbilical may reduce imbalances between the power cables of the triad. | 05-28-2015 |
David T. Hickman, Saint-Suipice CH
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20160136271 | Disaccharide Synthetic Lipid Compounds and Uses Thereof - Essentially pure compounds of the formulas (I) to (XX) are provided. Compositions and methods for enhancing or stimulating an immune response are also provided. The compounds, provided are advantageous in that the compounds are essentially pure and free from contaminants encountered when such compounds are purified from natural sources. | 05-19-2016 |
David T. Hickman, Strasbourg Cedex FR
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20110064795 | Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers - The invention relates to an immunogenic composition which comprises, firstly, a carrier and, secondly, as antigenic structure, conjugates comprising all or part of the amino acid sequences of at least one peptide derived from an extracellular loop of the P-170 protein, each peptide being combined with several molecules of fatty acid containing a carbon chain of between C12 and C24 so as to allow, under suitable administration conditions, the induction of anti-P-170 antibodies. | 03-17-2011 |
David T. Hickman, Saint-Sulpice CH
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20130273149 | DISACCHARIDE SYNTHETIC LIPID COMPOUNDS AND USES THEREOF - Essentially pure compounds of the formulas (I) to (XX) are provided. Compositions and methods for enhancing or stimulating an immune response are also provided. The compounds, provided are advantageous in that the compounds are essentially pure and free from contaminants encountered when such compounds are purified from natural sources. | 10-17-2013 |
20150110854 | Disaccharide Synthetic Lipid Compounds and Uses Thereof - Essentially pure compounds of the formulas (I) to (XXV) are provided. Compositions and methods for enhancing or stimulating an immune response are also provided. The compounds, provided are advantageous in that the compounds are essentially pure and free from contaminants encountered when such compounds are purified from natural sources. | 04-23-2015 |
Emma Hickman, Horsham GB
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20090156529 | RNAi Inhibition of Alpha-ENaC Expression - The invention relates to compositions and methods for modulating the expression of alpha-ENaC, and more particularly to the downregulation of alpha-ENaC expression by chemically modified oligonucleotides. | 06-18-2009 |
20100190714 | RNAi Inhibition of Alpha-ENaC Expression - The invention relates to compositions and methods for modulating the expression of alpha-ENaC, and more particularly to the downregulation of alpha-ENaC expression by chemically modified oligonucleotides. | 07-29-2010 |
20100210513 | RNAi Inhibition of Alpha-ENaC Expression - The invention relates to compositions and methods for modulating the expression of alpha-ENaC, and more particularly to the downregulation of alpha-ENaC expression by chemically modified oligonucleotides. | 08-19-2010 |
20100210514 | RNAi Inhibition of Alpha-ENaC Expression - The invention relates to compositions and methods for modulating the expression of alpha-ENaC, and more particularly to the downregulation of alpha-ENaC expression by chemically modified oligonucleotides. | 08-19-2010 |
20100216971 | RNAi Inhibition of Alpha-ENaC Expression - The invention relates to compositions and methods for modulating the expression of alpha-ENaC, and more particularly to the downregulation of alpha-ENaC expression by chemically modified oligonucleotides. | 08-26-2010 |
20100216972 | RNAi Inhibition of Alpha-ENaC Expression - The invention relates to compositions and methods for modulating the expression of alpha-ENaC, and more particularly to the downregulation of alpha-ENaC expression by chemically modified oligonucleotides. | 08-26-2010 |
20120115933 | Organic Compositions to Treat Beta-ENaC-Related Diseases - The present disclosure relates to RNAi agents useful in methods of treating Beta-ENaC-related diseases such as cystic fibrosis, pseudohypoaldosteronism type 1 (PHA1), Liddle's syndrome, hypertension, alkalosis, hypokalemia, and obesity-associated hypertension, using a therapeutically effective amount of a RNAi agent to Beta-ENaC. | 05-10-2012 |
20120115934 | Organic Compositions to Treat Beta-ENaC-Related Diseases - The present disclosure relates to RNAi agents useful in methods of treating Beta-ENaC-related diseases such as cystic fibrosis, pseudohypoaldosteronism type 1 (PHA1), Liddle's syndrome, hypertension, alkalosis, hypokalemia, and obesity-associated hypertension, using a therapeutically effective amount of a RNAi agent to Beta-ENaC. | 05-10-2012 |
20120122960 | Organic Compositions to Treat Beta-ENaC-Related Diseases - The present disclosure relates to RNAi agents useful in methods of treating Beta-ENaC-related diseases such as cystic fibrosis, pseudohypoaldosteronism type 1 (PHA1), Liddle's syndrome, hypertension, alkalosis, hypokalemia, and obesity-associated hypertension, using a therapeutically effective amount of a RNAi agent to Beta-ENaC. | 05-17-2012 |
20130012571 | Organic Compositions to Treat Beta-ENaC-Related Diseases - The present disclosure relates to RNAi agents useful in methods of treating Beta-ENaC-related diseases such as cystic fibrosis, pseudohypoaldosteronism type 1 (PHA1), Liddle's syndrome, hypertension, alkalosis, hypokalemia, and obesity-associated hypertension, using a therapeutically effective amount of a RNAi agent to Beta-ENaC. | 01-10-2013 |
20140107179 | ORGANIC COMPOSITIONS TO TREAT Beta-ENaC-RELATED DISEASES - The present disclosure relates to RNAi agents useful in methods of treating Beta-ENaC-related diseases such as cystic fibrosis, pseudohypoaldosteronism type 1 (PHA1), Liddle's syndrome, hypertension, alkalosis, hypokalemia, and obesity-associated hypertension, using a therapeutically effective amount of a RNAi agent to Beta-ENaC. | 04-17-2014 |
20150275218 | Organic Compositions to Treat Beta-ENaC-Related diseases - The present disclosure relates to RNAi agents useful in methods of treating BetaENaC-related diseases such as cystic fibrosis, pseudohypoaldosteronism type 1 (PHA1), Liddle's syndrome, hypertension, alkalosis, hypokalemia, and obesity-associated hypertension, using a therapeutically effective amount of a RNAi agent to Beta-ENaC. | 10-01-2015 |
20150284726 | RNAi Inhibition of A1pha-ENaC Expression - The invention relates to compositions and methods for modulating the expression of alpha-ENaC, and more particularly to the downregulation of alpha-ENaC expression by chemically modified oligonucleotides. | 10-08-2015 |
Emma Hickman, Sutton GB
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20110263681 | Organic Compositions to Treat Beta-ENaC-Related Diseases - The present disclosure relates to RNAi agents useful in methods of treating Beta-ENaC-related diseases such as cystic fibrosis, pseudohypoaldosteronism type 1 (PHA1), Liddle's syndrome, hypertension, alkalosis, hypokalemia, and obesity-associated hypertension, using a therapeutically effective amount of a RNAi agent to Beta-ENaC. | 10-27-2011 |
Gregory James Schoepen Hickman, University City, MO US
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20150013894 | Metallic Bladders - A method and apparatus is presented. A method may comprise positioning a metallic bladder within a tool, the tool having a number of die liners that generate heat when exposed to a magnetic field; applying the magnetic field to the number of die liners to heat the metallic bladder; and pressurizing the metallic bladder. | 01-15-2015 |
20150129118 | Compression Molding of Composite Structures Using Flexible Tooling - A tool for compression molding a composite laminate charge has a tool face for compressing the charge. A flexible tool feature on the tool face forms a shape in the charge and compensates for tool surfaces that may be out-of-tolerance. | 05-14-2015 |
20150137427 | Consolidation of Complex Contoured Thermoplastic Structures - A method and apparatus for forming a stiffened thermoplastic panel is presented. The method may comprise placing a number of forming tools within a number of concave areas of a thermoplastic preform. The method may also place the thermoplastic preform with the number of forming tools within the number of concave areas on a thermoplastic lay-up to form a workpiece. The method may also position the workpiece within a tool. The tool may have a number of die liners configured to generate heat in response to a magnetic field. The method may also consolidate the workpiece to form the stiffened thermoplastic panel. Consolidating may comprise applying a magnetic field to the number of die liners to heat the workpiece to a consolidation temperature. | 05-21-2015 |
20160082641 | Extruded Deposition of Fiber Reinforced Polymers - A fiber reinforced polymer part is fabricated by rastering a deposition head over a substrate, and additively forming part features by extruding a polymer having an entrained continuous reinforcement from the deposition head onto a substrate. | 03-24-2016 |
20160082659 | Extruded Deposition of Polymers Having Continuous Carbon Nanotube Reinforcements - A composite part is fabricated by rastering a deposition head over a substrate, and additively forming part features by extruding a polymer having an entrained continuous nanotube reinforcement from the deposition head onto a substrate. | 03-24-2016 |
Heather D. Hickman, Chevy Chase, MD US
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20150094213 | Comparative Ligand Mapping from MHC Positive Cells - A method of comparative ligand mapping to identify peptide ligands presented by MHC positive cells that distinguish an infected/transfected cell from an uninfected/non-transfected cell is disclosed. | 04-02-2015 |
Howard Oliver Hickman, Reigate GB
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20130004014 | GEOTAGGING OF AUDIO RECORDINGS - A method of geotagging an audio-recording. The method comprises: determining ( | 01-03-2013 |
James D. Hickman, Nelson CA
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20110055006 | Advertising Distribution System - The invention is a software system capable of managing advertisement campaigns across remote digital signage advertising participating locations. The system provides interfaces for advertisers, locations, system administrators and consumers. Central to the system is an algorithm that ensures advertising budgets are dispersed across a specified timeframe. This algorithm adapts to changes in campaign timeframes, price per advertisement impression, number of active locations, average display frequency per location and addition, revision or removal of advertisements. | 03-03-2011 |
John Hickman, Paris FR
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20090099072 | Motif of the Beclin Protein Which Interacts with Anti-Apoptotic Members of the Bcl-2 Protein Family, and Uses - The invention relates to a method of identifying modulators of programmed cell death, comprising an interaction between a motif of Beclin protein and an anti-apoptotic member of the family of Bcl-2 proteins and the detection of said interaction be means of fluorescence polarisation. The modulators identified on the basis of said method are administered to cancer patients in order to induce apoptotic- and/or autophagic-type programmed cell death. The invention also relates to a motif of the Beclin protein which can interact with an anti-apoptic member of the family of Bcl-2 proteins and to the use thereof in order to induce programmed cell death in a cancer patient. | 04-16-2009 |
20090325883 | Peptides Which Interact with Anti-Apoptotic Members of the BCL-2 Protein Family, and Uses - The invention lies within the field of seeking out and identifying new peptides which interact with anti-apoptotic members of the Bcl-2 protein family, by means of the two-hybrid system. | 12-31-2009 |
20100168149 | Camptothecin Analogue Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them - Compound of formula (I): | 07-01-2010 |
20100168150 | Camptothecin Analogue Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them. - Compound of formula (I): | 07-01-2010 |
20110034460 | Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them - Compounds of formula (I): | 02-10-2011 |
20110112104 | TRICYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. - Compounds of formula (I): | 05-12-2011 |
20110237644 | UBIQUITIN SPECIFIC PROTEASES RESPONSIBLE FOR MCL-1 STABILITY AND USES THEREOF - Use of a polypeptide selected from the group consisting of USP13, USP26, USP38, USP42 or USP46 as a screening tool for an agent for treating cancer. | 09-29-2011 |
20130331380 | DIHYDROINDOLONE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Compounds of formula (I): | 12-12-2013 |
20150051189 | INDOLIZINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Compounds of formula (I): | 02-19-2015 |
20150313911 | INDOLIZINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Compounds of formula (I): | 11-05-2015 |
Kevin Jonathan Hickman, Oxon GB
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20090212891 | COIL ENERGIZATION APPARATUS AND METHOD OF ENERGIZING A SUPERCONDUCTIVE COIL - A coil energizing apparatus has a superconducting energization power supply having an output port. The power supply is arranged to generate, when in use, a pulsed output current signal at the output port. | 08-27-2009 |
Lynsey Hickman, Chesterfield GB
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20160040089 | Lubricating Composition Including Esterified Copolymer And Low Dispersant Levels Suitable For Driveline Applications - A lubricating composition, method of making, and method of use are disclosed. The lubricant includes an esterified copolymer including a backbone that includes units derived from a vinyl aliphatic monomer and units derived from a carboxylic acid monomer, the carboxylic acid monomer comprising an α,β-ethylenically unsaturated dicarboxylic acid or derivative thereof. The lubricating composition also includes an oil of lubricating viscosity. The lubricating composition includes no more than 2.5 wt. % of dispersant for dispersing oxidation products, other than the esterified copolymer. | 02-11-2016 |
Lynsey Hickman, Belper GB
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20150203784 | Lubricating Composition Including Esterified Copolymer And Diene Rubber Polymer - A lubricating composition includes (A) an esterified copolymer comprising units (A1) derived from a vinyl monomer and units (A2) derived from a carboxylic acid monomer, the vinyl monomer comprising a vinyl aliphatic monomer, the carboxylic acid monomer comprising an ethylenically unsaturated carboxylic acid or derivative thereof, esterified with a primary alcohol; and (B) a diene rubber copolymer comprising at least a first block (B1) derived from a conjugated diene monomer and at least a second block (B2) derived from a vinyl aromatic monomer. A ratio of the diene rubber copolymer to the esterified copolymer in the lubricating composition (B:A) is from 0.01 to 0.9, by weight. | 07-23-2015 |
Melissa Renee Hickman, Alexandrai, KY US
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20150266633 | PACKAGE OF WET WIPES WITH EASY OPENABILITY, IMPROVED MOISTURE RETENTION AND MANUFACTURING EFFICIENCY - A package containing a stack of wet wipes moistened with aqueous lotion is disclosed. The package comprises a polymeric film wrap, the film wrap comprising a laminate with an inner layer of a first polymer and an outer layer of a second polymer, and a surface bearing scoring along a path defining a substantially closed shape, the scoring at least partially penetrating the outer layer and not entirely penetrating the inner layer. | 09-24-2015 |
Melissa Renee Hickman, Alexandria, KY US
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20160088981 | PACKAGE OF WET WIPES WITH EASY OPENABILITY,IMPROVED MOISTURE RETENTION AND MANUFACTURING EFFICIENCY - A package containing a stack of wet wipes moistened with aqueous lotion is disclosed. The package comprises a polymeric film wrap, the film wrap comprising a laminate with an inner layer of a first polymer and an outer layer of a second polymer, and a surface bearing scoring along a path defining a substantially closed shape, the scoring at least partially penetrating the outer layer and not entirely penetrating the inner layer. | 03-31-2016 |
Neil Alex Hickman, Reading GB
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20130207376 | SECURITY ELEMENT, SECURITY DOCUMENT AND METHODS OF MANUFACTURE THEREOF - A security element for a security booklet includes a plurality of pages including a first outermost page and a second outermost page. The security element includes at least one line of stitching joining the plurality of pages to one another. The stitching is formed of at least a first thread and a second thread, the first thread disposed on an outer surface of the first page, and the second thread disposed on an outer surface of the second page. The first and second threads interlock at each of a series of spaced apertures through the plurality of pages along the line of stitching. At one or more selected aperture(s), a loop of the second thread extends to the outer surface of the first page. The first thread has an optical characteristic different from the second thread, so the second thread at the selected aperture(s) is distinguishable from the first thread. | 08-15-2013 |
Nichola Jane Inglis Hickman, Newbury GB
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20130166352 | MOBILE CATEGORIZATION - Method and system for assigning a category to a user comprising the steps of: obtaining network usage records from a mobile network. Extracting cell information from the network usage records. Determining location information from the extracted cell information. Generating one or more user behaviour attributes from the determined location information. Assigning a user category to the user based on the determined one or more user behaviour attributes. | 06-27-2013 |
20130183927 | TRANSPORT SYSTEM - Method and system of detecting traffic in a transport network comprising obtaining network usage records from a mobile network. Extracting cell information from the network usage records. Identifying the network usage records originating from moving handsets from the extracted cell information. Matching the identified network usage records with one or more transport routes. Matching each of the one or more transport routes with a transport mode using transport mode map data. | 07-18-2013 |
20130183928 | METHODS OF ANALYSING A CELLULAR NETWORK - There is provided a method of establishing a likelihood of one or more cellular terminal carriers travelling to a predetermined location, using cellular network data. The method comprises the steps of: obtaining network usage records from a cellular network; extracting cell information from the network usage records; establishing terminal carrier routes for cellular terminals that have changed location as determined from the extracted cell information; deriving terminal carrier profile attributes for the terminal carriers that have changed location, based on the established terminal carrier routes; and establishing the likelihood of one or more cellular terminal carriers travelling to the predetermined location, based on the established terminal carrier routes and the derived terminal carrier profile attributes. By combining a terminal carrier route with one or more terminal carrier profile attributes, a more precise and accurate inference of the likelihood of the cellular terminal carrier travelling to a predetermined location, or attending an event, may be obtained. | 07-18-2013 |
20130183996 | METHODS OF ANALYSING A CELLULAR NETWORK - A method of managing a load within a cellular network. The method includes obtaining network usage records from the cellular network; extracting cell information from the network usage records; establishing terminal carrier routes for cellular terminals that have changed location as determined from the extracted cell information; deriving terminal carrier profile attributes for the cellular terminals that have changed location, based on the established terminal carrier routes; determining a load on a resource of the cellular network, based on the established terminal carrier routes and the derived terminal carrier profile attributes; and controlling resources of the cellular network in response to the determined load, so as to manage the load within the cellular network. By combining established terminal carrier routes with derived terminal carrier profile attributes, it is possible to anticipate areas where cellular terminal carriers are likely to be concentrated at specific times during the day and allocate resources accordingly. | 07-18-2013 |
Nichola Jane Inglis Hickman, Wallingford GB
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20160069692 | DETERMINATION OF A ROUTE OF A MOBILE DEVICE IN A MOBILE NETWORK - A method and system for determining a traveled route of a mobile device in a mobile network. A determination is made of a series of consecutive movements of the mobile device along a path of locations from an origin location of the path at an earliest activity of a plurality of activities of the mobile device to a destination location of the path at a latest activity of the plurality of activities. Historical sets of routes of the mobile device are accessed from storage. At least one common route is ascertained from the set of routes, wherein the locations in each common route include all of the locations on the path. A common route of the at least one common route is designated as the traveled route of the mobile device. | 03-10-2016 |
Philip Hickman, Wellsville, KS US
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20160030969 | VISCOUS MATERIAL WARMING DEVICE - A viscous material warming device comprising a housing, where the housing is surrounded with an insulated wall; a lid atop the housing; an upper plate mounted within the housing, where the upper plate includes a plurality of upper receiving holes each to accept a material tube, and where the upper plate includes spacer holes; a lower plate mounted within the housing below the upper plate, where the lower plate includes a plurality of lower receiving holes each to accept a tip of the material tube, and where the lower plate includes spacer holes; at least three spacers positioned between the upper plate and the lower plate, where the spacers are positioned within the spacer holes of each the upper plate and the lower plate; and a heater positioned within the lower plate, where the heater includes a thermometer to maintain the housing at a constant temperature. | 02-04-2016 |
Robert K. Hickman, Winchester, MA US
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20150344564 | Viral Inactivation During Purification of Antibodies - Described herein are methods for isolating and purifying antibodies from a sample matrix. One aspect of the present disclosure is directed to viral reduction/inactivation of samples generated in the various steps of antibody purification. In a particular aspect, methods herein employ an acidification step followed by one or more chromatography steps. The chromatography steps can include one or more of the following chromatographic procedures: ion exchange chromatography, affinity chromatography, and hydrophobic interaction chromatography. | 12-03-2015 |
Robert W. Hickman, Lexington, SC US
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20160029799 | HANGABLE ARTIST'S EASEL AND ACCESORIES - A space saving, door or wall-mountable artist's easel with a framework adapted to receive and hold an artist's canvas, art panel, clipboard, or some other item that would normally be affixed to an easel with a mounting bracket attached to the frame so the entire device may be hung on a door or wall. The easel can be used while mounted. In one example, a front pivoting frame enables the mounted piece to be extended outward from a back stationary frame. A height adjustment mechanism allows the mounted piece to be raised or lowered to a desired position, enabling the artist to stand or sit. The compactness of the easel enables an art piece being worked on to be left mounted to the easel for drying or viewing, and the door can still be opened and closed normally with the easel mounted to it. | 02-04-2016 |
Robert Wayne Hickman, Lexington, SC US
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20140263922 | Artist's Easel Attachable to a Door - A space saving, door-mountable artist's easel with a framework adapted to receive and hold an artist's canvas, art panel, clipboard, or some other item that would normally be affixed to an easel with a mounting bracket attached to the frame so the entire device may be hung on a door. The easel can be used while mounted to the door it is stored on. In one example, a front pivoting frame enables the mounted piece to be extended outward from a back stationary frame. A height adjustment mechanism allows the mounted piece to be raised or lowered to a desired position, enabling the artist to stand or sit. The compactness of the easel enables an art piece being worked on to be left mounted to the easel for drying or viewing, and the door can still be opened and closed normally with the easel mounted to it. | 09-18-2014 |