Patent application number | Description | Published |
20090275139 | MATERIALS AND METHODS RELATING TO THE PRODUCTION AND MAINTENANCE OF CELL LINES - The invention provides methods for maintaining cell lines from primary cells, i.e., non-transformed cells, using expression of the signal transducer of activation and transcription (STAT). The methods are particularly suitable for maintenance of B-cells. | 11-05-2009 |
20120157662 | MEANS AND METHODS FOR PRODUCING HIGH AFFINITY ANTIBODIES - The invention provides means and methods for modulating the occurrence of somatic hypermutations in antibody producing plasmablast-like B-cells. | 06-21-2012 |
20130331552 | MEANS AND METHODS FOR PRODUCING HIGH AFFINITY ANTIBODIES - Described are means and methods for producing high-affinity antibodies against an antigen of interest, using stable B-cell cultures. | 12-12-2013 |
20140037618 | METHOD OF TREATING AUTOIMMUNE INFLAMMATORY DISORDERS USING IL-23R LOSS-OF-FUNCTION MUTANTS - The present invention relates to compositions and methods of diagnosing and treating autoimmune and inflammatory disorders that are characterized by IL-23R loss-of-function mutations. | 02-06-2014 |
20140072575 | RSV-SPECIFIC BINDING MOLECULES AND MEANS FOR PRODUCING THEM - The invention provides antibodies and functional equivalents thereof which are capable of specifically binding RSV, and means and methods for producing them. | 03-13-2014 |
20140377279 | RSV-SPECIFIC BINDING MOLECULES AND MEANS FOR PRODUCING THEM - The invention provides antibodies and functional equivalents thereof which are capable of specifically binding RSV, and means and methods for producing them. | 12-25-2014 |
20150010566 | INFLUENZA A VIRUS SPECIFIC ANTIBODIES - The invention relates to isolated, synthetic or recombinant antibodies and functional parts thereof specific for multiple influenza A virus subtypes. The invention further relates to the use of such antibodies for diagnosis of an influenza A virus infection and as a medicament and/or prophylactic agent for at least in part treating or alleviating symptoms of an influenza A virus infection. | 01-08-2015 |
20150203816 | MEANS AND METHODS FOR INFLUENCING THE STABILITY OF CELLS - The invention provides a method for influencing the stability of an antibody producing cell, comprising directly or indirectly influencing the amount of BCL6 and/or Blimp 1 expression product within said antibody producing cell. Stable antibody producing cells and cell lines arc also provided, as well as methods for producing antibodies using such cells and/or cell lines. | 07-23-2015 |