Patent application number | Description | Published |
20090053125 | Stabilizing 4H Polytype During Sublimation Growth Of SiC Single Crystals - A SiC single crystal is grown by physical vapor transport (PVT) in a graphite growth chamber, the interior of which is charged with a SiC source material and a SiC single crystal seed in spaced relation. During PVT growth of the SiC single crystal, the growth chamber further includes Ce. The SiC single crystal grows on the SiC single crystal seed in response to heating the interior of the growth chamber to a growth temperature and in the presence of a temperature gradient in the growth chamber whereupon the temperature of the SiC single crystal seed is lower than the temperature of the SiC source material. The Ce can include either Ce silicide or Ce carbide. | 02-26-2009 |
20090169459 | Intra-Cavity Gettering of Nitrogen in Sic Crystal Growth - In method of crystal growth, an interior of a crystal growth chamber ( | 07-02-2009 |
20100018455 | System for Forming SiC Crystals Having Spatially Uniform Doping Impurities - A physical vapor transport system includes a growth chamber charged with source material and a seed crystal in spaced relation, and at least one capsule having at least one capillary extending between an interior thereof and an exterior thereof, wherein the interior of the capsule is charged with a dopant. Each capsule is installed in the growth chamber. Through a growth reaction carried out in the growth chamber following installation of each capsule therein, a crystal is formed on the seed crystal using the source material, wherein the formed crystal is doped with the dopant. | 01-28-2010 |
20100061914 | GUIDED DIAMETER SiC SUBLIMATION GROWTH WITH MULTI-LAYER GROWTH GUIDE - In the growth of a SiC boule, a growth guide is provided inside of a growth crucible that is charged with SiC source material at a bottom of the crucible and a SiC seed crystal at a top of the crucible. The growth guide has an inner layer that defines at least part of an opening in the growth guide and an outer layer that supports the inner layer in the crucible. The opening faces the source material with the seed crystal positioned at an end of the opening opposite the source material. The inner layer is formed from a first material having a higher thermal conductivity than the second, different material forming the outer layer. The source material is sublimation grown on the seed crystal in the growth crucible via the opening in the growth guide to thereby form the SiC boule on the seed crystal. | 03-11-2010 |
20110303884 | SiC Crystals Having Spatially Uniform Doping Impurities - A sublimation-grown silicon carbide (SiC) single crystal boule includes a deep level dopant introduced into the SiC single crystal boule during sublimation-growth thereof such that in a continuous section of the boule that is not less than 50% of a continuous length of said boule, the deep level dopant concentration at the boule center varies by not more than 25% from the average concentration of the deep level dopant in the continuous section of the boule. | 12-15-2011 |
20120103249 | SIC SINGLE CRYSTAL SUBLIMATION GROWTH METHOD AND APPARATUS - A physical vapor transport growth system includes a growth chamber charged with SiC source material and a SiC seed crystal in spaced relation and an envelope that is at least partially gas-permeable disposed in the growth chamber. The envelope separates the growth chamber into a source compartment that includes the SiC source material and a crystallization compartment that includes the SiC seed crystal. The envelope is formed of a material that is reactive to vapor generated during sublimation growth of a SiC single crystal on the SiC seed crystal in the crystallization compartment to produce C-bearing vapor that acts as an additional source of C during the growth of the SiC single crystal on the SiC seed crystal. | 05-03-2012 |
20120225004 | Halosilane Assisted PVT Growth of SiC - In a physical vapor transport growth technique for silicon carbide a silicon carbide powder and a silicon carbide seed crystal are introduced into a physical vapor transport growth system and halosilane gas is introduced separately into the system. The source powder, the halosilane gas, and the seed crystal are heated in a manner that encourages physical vapor transport growth of silicon carbide on the seed crystal, as well as chemical transformations in the gas phase leading to reactions between halogen and chemical elements present in the growth system. | 09-06-2012 |
20120285370 | SUBLIMATION GROWTH OF SIC SINGLE CRYSTALS - In SiC sublimation crystal growth, a crucible is charged with SiC source material and SiC seed crystal in spaced relation and a baffle is disposed in the growth crucible around the seed crystal. A first side of the baffle in the growth crucible defines a growth zone where a SiC single crystal grows on the SiC seed crystal. A second side of the baffle in the growth crucible defines a vapor-capture trap around the SiC seed crystal. The growth crucible is heated to a SiC growth temperature whereupon the SiC source material sublimates and forms a vapor which is transported to the growth zone where the SiC crystal grows by precipitation of the vapor on the SiC seed crystal. A fraction of this vapor enters the vapor-capture trap where it is removed from the growth zone during growth of the SiC crystal. | 11-15-2012 |
20130280466 | Large Diameter, High Quality SiC Single Crystals, Method and Apparatus - A method and system of forming large-diameter SiC single crystals suitable for fabricating high crystal quality SiC substrates of 100, 125, 150 and 200 mm in diameter are described. The SiC single crystals are grown by a seeded sublimation technique in the presence of a shallow radial temperature gradient. During SiC sublimation growth, a flux of SiC bearing vapors filtered from carbon particulates is substantially restricted to a central area of the surface of the seed crystal by a separation plate disposed between the seed crystal and a source of the SiC bearing vapors. The separation plate includes a first, substantially vapor-permeable part surrounded by a second, substantially non vapor-permeable part. The grown crystals have a flat or slightly convex growth interface. Large-diameter SiC wafers fabricated from the grown crystals exhibit low lattice curvature and low densities of crystal defects, such as stacking faults, inclusions, micropipes and dislocations. | 10-24-2013 |
20130309496 | "Method for Synthesizing Ultrahigh-Purity Silicon Carbide" - In a method of forming polycrystalline SiC grain material, low-density, gas-permeable and vapor-permeable bulk carbon is positioned at a first location inside of a graphite crucible and a mixture of elemental silicon and elemental carbon is positioned at a second location inside of the graphite crucible. Thereafter, the mixture and the bulk carbon are heated to a first temperature below the melting point of the elemental Si to remove adsorbed gas, moisture and/or volatiles from the mixture and the bulk carbon. Next, the mixture and the bulk carbon are heated to a second temperature that causes the elemental Si and the elemental C to react forming as-synthesized SiC inside of the crucible. The as-synthesized SiC and the bulk carbon are then heated in a way to cause the as-synthesized SiC to sublime and produce vapors that migrate into, condense on and react with the bulk carbon forming polycrystalline SiC material. | 11-21-2013 |
20130320275 | Vanadium Compensated, SI SiC Single Crystals of NU and PI Type and the Crystal Growth Process Thereof - In a crystal growth apparatus and method, polycrystalline source material and a seed crystal are introduced into a growth ambient comprised of a growth crucible disposed inside of a furnace chamber. In the presence of a first sublimation growth pressure, a single crystal is sublimation grown on the seed crystal via precipitation of sublimated source material on the seed crystal in the presence of a flow of a first gas that includes a reactive component that reacts with and removes donor and/or acceptor background impurities from the growth ambient during said sublimation growth. Then, in the presence of a second sublimation growth pressure, the single crystal is sublimation grown on the seed crystal via precipitation of sublimated source material on the seed crystal in the presence of a flow of a second gas that includes dopant vapors, but which does not include the reactive component. | 12-05-2013 |
20140234194 | Vanadium Doped SiC Single Crystals and Method Thereof - A sublimation grown SiC single crystal includes vanadium dopant incorporated into the SiC single crystal structure via introduction of a gaseous vanadium compound into a growth environment of the SiC single crystal during growth of the SiC single crystal. | 08-21-2014 |
Patent application number | Description | Published |
20090076795 | System And Method Of Generating Responses To Text-Based Messages - In accordance with one aspect of the present invention, an automated method of and system for generating a response to a text-based natural language message is disclosed. The method includes identifying a sentence in the text-based natural language message. Also, identifying an input clause in the sentence. Further, comparing the input clause to a previously received clause, where the previously received clause is correlated with a previously generated response message. Additionally, generating an output response message based on the previously generated response message. The system includes means for performing the method steps. | 03-19-2009 |
20090234853 | Finding the website of a business using the business name - A system and method are provided for augmenting information on business directory databases. Using the business name contained in a business directory database and Web data mining technology, the website of a business is found and validated, prior to enriching the database entries. | 09-17-2009 |
20090254498 | System and method for identifying critical emails - Disclosed is a method and system for identifying critical emails. To identify critical emails, a critical email classifier is trained from training data comprising labeled emails. The classifier extracts N-grams from the training data and identifies N-gram features from the extracted N-grams. The classifier also extracts salient features from the training data. The classifier is trained based on the identified N-gram features and the salient features so that the classifier can classify unlabeled emails as critical emails or non-critical emails. | 10-08-2009 |
20120065963 | System And Method Of Generating Responses To Text-Based Messages - In accordance with one aspect of the present invention, an automated method of and system for generating a response to a text-based natural language message is disclosed. The method includes identifying a first selected input clause in a sentence in the text-based natural language message. Also, assigning a semantic tag to the first selected input clause and matching the semantic tag to a historical input tag. The historical input tag associated with a first previously generated response clause. Further; generating an output response message based on the historical response clause, the output response message derived from the historical input tag and a second previously generated response clause. The system includes means for performing the method steps. | 03-15-2012 |
20120278361 | USING WEB-MINING TO ENRICH DIRECTORY SERVICE DATABASES AND SOLICITING SERVICE SUBSCRIPTIONS - A system and method are provided for augmenting information on business directory databases and communicating with businesses is disclosed. Using the enriched business directory database and Web mining technology, customized email message are sent inviting businesses to enter their enriched business information into the directory or even subscribe to other paid services provided by the directory service. | 11-01-2012 |
20130024389 | METHOD AND APPARATUS FOR EXTRACTING BUSINESS-CENTRIC INFORMATION FROM A SOCIAL MEDIA OUTLET - A method, non-transitory computer readable medium and apparatus for extracting business centric information from a social media outlet are disclosed. For example, the method obtains a plurality of messages from a social media outlet, classifies a subset of the plurality of messages obtained from the social media outlet as problem messages, extracts problem phrases by extracting a problem phrase from each one of the problem messages, and correlates a problem to a third party entity with the problem phrases. | 01-24-2013 |
20130035932 | SYSTEM AND METHOD OF GENERATING RESPONSES TO TEXT-BASED MESSAGES - A system to generate a response to a text-based natural language message includes a user interface, processing device, and a computer-readable storage medium storing executable instructions to generate the response to the text-based natural language message. The instructions and a method for generating the response include identifying a sentence in the text-based natural language message, identifying an input clause in the sentence, and parsing the input clause, thereby defining a relationship between words in the input clause. The instructions and method also include assigning a semantic tag to the parsed input clause, comparing the input clause to a previously received clause, the previously received clause being correlated with a previously generated response clause, and generating an output response message derived from the previously generated response clause. | 02-07-2013 |
Patent application number | Description | Published |
20080235740 | System and method for storing advertising data - A computerized method is disclosed for presenting advertising data extracted from a video data stream, the method including storing a plurality of advertising data items extracted from the video data stream at an end user device; and displaying a plurality of sorted advertising indicator data items at the end user device, wherein each of the advertising indicator data items indicates one of the plurality of stored advertising data items. A system is disclosed for performing the method. A data structure is disclosed providing a functional and structural interrelationship between a processor in the system and data in the data structure. | 09-25-2008 |
20090070113 | SYSTEM FOR HANDLING FREQUENTLY ASKED QUESTIONS IN A NATURAL LANGUAGE DIALOG SERVICE - A voice-enabled help desk service is disclosed. The service comprises an automatic speech recognition module for recognizing speech from a user, a spoken language understanding module for understanding the output from the automatic speech recognition module, a dialog management module for generating a response to speech from the user, a natural voices text-to-speech synthesis module for synthesizing speech to generate the response to the user, and a frequently asked questions module. The frequently asked questions module handles frequently asked questions from the user by changing voices and providing predetermined prompts to answer the frequently asked question. | 03-12-2009 |
20100042404 | METHOD FOR BUILDING A NATURAL LANGUAGE UNDERSTANDING MODEL FOR A SPOKEN DIALOG SYSTEM - A method of generating a natural language model for use in a spoken dialog system is disclosed. The method comprises using sample utterances and creating a number of hand crafted rules for each call-type defined in a labeling guide. A first NLU model is generated and tested using the hand crafted rules and sample utterances. A second NLU model is built using the sample utterances as new training data and using the hand crafted rules. The second NLU model is tested for performance using a first batch of labeled data. A series of NLU models are built by adding a previous batch of labeled data to training data and using a new batch of labeling data as test data to generate the series of NLU models with training data that increases constantly. If not all the labeling data is received, the method comprises repeating the step of building a series of NLU models until all labeling data is received. After all the training data is received, at least once, the method comprises building a third NLU model using all the labeling data, wherein the third NLU model is used in generating the spoken dialog service. | 02-18-2010 |
20100239076 | Providing Called Number Characteristics to Click-to-Dial Customers - A system and method to provide content and call attributes for a destination phone number using a click-to-dial connection includes accepting a query, retrieving links to a document, and searching through cached data using the query to identify relevant or destination number information. If no match is found, the method continues with accessing the document identified by the link for identifying relevant number information and creating a click-to-dial icon to link to the relevant numbers included in the relevant phone number information identified by the query. Next, a popup box for content relevant to the click-to-dial icon and a click feature on the popup box are created to retrieve call destination attributes for viewing by a user. Further, computer instructions create at least one communication connection between two communication devices after viewing call destination attributes. | 09-23-2010 |
20120022950 | Systems and Methods for Targeted Advertising in Voicemail to Text Systems - Systems and methods are provided for a voice message to text system supporting targeted advertisements. Voice messages received from users are converted to raw text messages that are normalized to insert proper punctuation and extract entity information. The normalized text and entity information are processed to extract concepts, such as critical phrases, from the normalized text. Extracted concepts are then matched to advertisements on an advertisement database having user selection criteria. Advertisements having selection criteria matching the extracted concepts are transmitted to the users, and the advertisers that placed the advertisements are charged fees for the advertisements. User profile information and user context information can additionally be used to select advertisements for transmission to users. | 01-26-2012 |
20120076284 | Providing Called Number Characteristics to Click-to-Dial Customers - A system and method to provide content and call attributes for a destination phone number using a click-to-dial connection includes accepting a query, retrieving links to a document, and searching through cached data using the query to identify relevant or destination number information. If no match is found, the method continues with accessing the document identified by the link for identifying relevant number information and creating a click-to-dial icon to link to the relevant numbers included in the relevant phone number information identified by the query. Next, a popup box for content relevant to the click-to-dial icon and a click feature on the popup box are created to retrieve call destination attributes for viewing by a user. Further, computer instructions create at least one communication connection between two communication devices after viewing call destination attributes. | 03-29-2012 |
20120239383 | SYSTEM AND METHOD OF SPOKEN LANGUAGE UNDERSTANDING IN HUMAN COMPUTER DIALOGS - A system and method are disclosed that improve automatic speech recognition in a spoken dialog system. The method comprises partitioning speech recognizer output into self-contained clauses, identifying a dialog act in each of the self-contained clauses, qualifying dialog acts by identifying a current domain object and/or a current domain action, and determining whether further qualification is possible for the current domain object and/or current domain action. If further qualification is possible, then the method comprises identifying another domain action and/or another domain object associated with the current domain object and/or current domain action, reassigning the another domain action and/or another domain object as the current domain action and/or current domain object and then recursively qualifying the new current domain action and/or current object. This process continues until nothing is left to qualify. | 09-20-2012 |
20130166284 | System and Method of Spoken Language Understanding in Human Computer Dialogs - A system and method are disclosed that improve automatic speech recognition in a spoken dialog system. The method comprises partitioning speech recognizer output into self-contained clauses, identifying a dialog act in each of the self-contained clauses, qualifying dialog acts by identifying a current domain object and/or a current domain action, and determining whether further qualification is possible for the current domain object and/or current domain action. If further qualification is possible, then the method comprises identifying another domain action and/or another domain object associated with the current domain object and/or current domain action, reassigning the another domain action and/or another domain object as the current domain action and/or current domain object and then recursively qualifying the new current domain action and/or current object. This process continues until nothing is left to qualify. | 06-27-2013 |
20130311170 | Methods and Systems for Natural Language Understanding Using Human Knowledge and Collected Data - Disclosed herein are systems and methods to incorporate human knowledge when developing and using statistical models for natural language understanding. The disclosed systems and methods embrace a data-driven approach to natural language understanding which progresses seamlessly along the continuum of availability of annotated collected data, from when there is no available annotated collected data to when there is any amount of annotated collected data. | 11-21-2013 |
20140011544 | VOICE-OPERATED INTERFACE FOR DTMF-CONTROLLED SYSTEMS - An arrangement for allowing “hands-free” access to DTMF-controlled systems, such as one's voice mail messaging systems, utilizes a speech-to-DTMF tone application that monitors the communication between the user and the DTMF-controlled system. A speech recognition unit is utilized to retrieve certain voice commands (e.g., “next”, “skip”, “repeat”, “forward”, etc.) when uttered by the user. The application then translates the received commands into the proper DTMF tone sequence used by the DTMF-controlled system and transmits the DTMF tones to the system. The application is particularly useful in the cell phone environment and avoids the necessity of the user to constantly switch between using the keypad and listening to messages/commands from the system. | 01-09-2014 |
20140029746 | Providing Called Number Characteristics to Click-to-Dial Customers - A system and method to provide content and call attributes for a destination phone number using a click-to-dial connection includes accepting a query, retrieving links to a document, and searching through cached data using the query to identify relevant or destination number information. If no match is found, the method continues with accessing the document identified by the link for identifying relevant number information and creating a click-to-dial icon to link to the relevant numbers included in the relevant phone number information identified by the query. Next, a popup box for content relevant to the click-to-dial icon and a click feature on the popup box are created to retrieve call destination attributes for viewing by a user. Further, computer instructions create at least one communication connection between two communication devices after viewing call destination attributes. | 01-30-2014 |
20140074477 | System and Method of Spoken Language Understanding in Human Computer Dialogs - A system and method are disclosed that improve automatic speech recognition in a spoken dialog system. The method comprises partitioning speech recognizer output into self-contained clauses, identifying a dialog act in each of the self-contained clauses, qualifying dialog acts by identifying a current domain object and/or a current domain action, and determining whether further qualification is possible for the current domain object and/or current domain action. If further qualification is possible, then the method comprises identifying another domain action and/or another domain object associated with the current domain object and/or current domain action, reassigning the another domain action and/or another domain object as the current domain action and/or current domain object and then recursively qualifying the new current domain action and/or current object. This process continues until nothing is left to qualify. | 03-13-2014 |
20140149121 | Method of Handling Frequently Asked Questions in a Natural Language Dialog Service - A voice-enabled help desk service is disclosed. The service comprises an automatic speech recognition module for recognizing speech from a user, a spoken language understanding module for understanding the output from the automatic speech recognition module, a dialog management module for generating a response to speech from the user, a natural voices text-to-speech synthesis module for synthesizing speech to generate the response to the user, and a frequently asked questions module. The frequently asked questions module handles frequently asked questions from the user by changing voices and providing predetermined prompts to answer frequently asked questions. | 05-29-2014 |
20140330555 | Methods and Systems for Natural Language Understanding Using Human Knowledge and Collected Data - Disclosed herein are systems and methods to incorporate human knowledge when developing and using statistical models for natural language understanding. The disclosed systems and methods embrace a data-driven approach to natural language understanding which progresses seamlessly along the continuum of availability of annotated collected data, from when there is no available annotated collected data to when there is any amount of annotated collected data. | 11-06-2014 |
20150019210 | SYSTEM AND METHOD OF EXTRACTING CLAUSES FOR SPOKEN LANGUAGE UNDERSTANDING - A clausifier and method of extracting clauses for spoken language understanding are disclosed. The method relates to generating a set of clauses from speech utterance text and comprises inserting at least one boundary tag in speech utterance text related to sentence boundaries, inserting at least one edit tag indicating a portion of the speech utterance text to remove, and inserting at least one conjunction tag within the speech utterance text. The result is a set of clauses that may be identified within the speech utterance text according to the inserted at least one boundary tag, at least one edit tag and at least one conjunction tag. The disclosed clausifier comprises a sentence boundary classifier, an edit detector classifier, and a conjunction detector classifier. The clausifier may comprise a single classifier or a plurality of classifiers to perform the steps of identifying sentence boundaries, editing text, and identifying conjunctions within the text. | 01-15-2015 |
20150025886 | SYSTEM AND METHOD OF EXTRACTING CLAUSES FOR SPOKEN LANGUAGE UNDERSTANDING - A clausifier for extracting clauses for spoken language understanding is disclosed. The method relates to generating a set of clauses from speech utterance text and comprises inserting at least one boundary tag in speech utterance text related to sentence boundaries, inserting at least one edit tag indicating a portion of the speech utterance text to remove, and inserting at least one conjunction tag within the speech utterance text. The result is a set of clauses that may be identified within the speech utterance text according to the inserted at least one boundary tag, at least one edit tag and at least one conjunction tag. The disclosed clausifier comprises a sentence boundary classifier, an edit detector classifier, and a conjunction detector classifier. The clausifier may comprise a single classifier or a plurality of classifiers to perform the steps of identifying sentence boundaries, editing text, and identifying conjunctions within the text. | 01-22-2015 |
20150057051 | Voice-Operated Interface for DTMF-Controlled Systems - An arrangement for allowing “hands-free” access to DTMF-controlled systems, such as one's voice mail messaging systems, utilizes a speech-to-DTMF tone application that monitors the communication between the user and the DTMF-controlled system. A speech recognition unit is utilized to retrieve certain voice commands (e.g., “next”, “skip”, “repeat”, “forward”, etc.) when uttered by the user. The application then translates the received commands into the proper DTMF tone sequence used by the DTMF-controlled system and transmits the DTMF tones to the system. The application is particularly useful in the cell phone environment and avoids the necessity of the user to constantly switch between using the keypad and listening to messages/commands from the system. | 02-26-2015 |
20160026618 | SYSTEM AND METHOD OF EXTRACTING CLAUSES FOR SPOKEN LANGUAGE UNDERSTANDING - A clausifier and method of extracting clauses for spoken language understanding are disclosed. The method relates to generating a set of clauses from speech utterance text and comprises inserting at least one boundary tag in speech utterance text related to sentence boundaries, inserting at least one edit tag indicating a portion of the speech utterance text to remove, and inserting at least one conjunction tag within the speech utterance text. The result is a set of clauses that may be identified within the speech utterance text according to the inserted at least one boundary tag, at least one edit tag and at least one conjunction tag. The disclosed clausifier comprises a sentence boundary classifier, an edit detector classifier, and a conjunction detector classifier. The clausifier may comprise a single classifier or a plurality of classifiers to perform the steps of identifying sentence boundaries, editing text, and identifying conjunctions within the text. | 01-28-2016 |
20160088142 | VOICE-OPERATED INTERFACE FOR DTMF-CONTROLLED SYSTEMS - An arrangement for allowing “hands-free” access to DTMF-controlled systems, such as one's voice mail messaging systems, utilizes a speech-to-DTMF tone application that monitors the communication between the user and the DTMF-controlled system. A speech recognition unit is utilized to retrieve certain voice commands (e.g., “next”, “skip”, “repeat”, “forward”, etc.) when uttered by the user. The application then translates the received commands into the proper DTMF tone sequence used by the DTMF-controlled system and transmits the DTMF tones to the system. The application is particularly useful in the cell phone environment and avoids the necessity of the user to constantly switch between using the keypad and listening to messages/commands from the system. | 03-24-2016 |
Patent application number | Description | Published |
20080293796 | Parenteral and oral formulations of benzimidazoles - Provided herein are drug delivery systems comprising nanosuspension formulations suitable for parenteral delivery to a subject. The nanosuspension formulations may comprise a benzimidazole derivative, e.g., mebendazole, and surface stabilizers, such as block copolymer(s), e.g., Pluronic F108, and surfactant(s), e.g., Tween 80, and, optionally, water. Provided are methods for defining nanosuspensions of a benzimidazole derivative as having maximum therapeutic efficacy for a treatment regimen by adjusting and/or selecting particles size(s) based on pharmacokinetic parameters of the derivative in the tissue. Also provided are methods for improving the bioavailability of a benzimidazole derivative during treatment of a pathophysiological condition and for treating a cancer by using formulation(s) combining particle diameters whereby the retention of the benzimidazole derivative within the particles increases as the diameter increases such that, upon administration, release of the benzimidazole derivative from the particles into tissue is continuous over a range of time as determined by the particle diameters. | 11-27-2008 |
20090048322 | Parenteral and oral formulations of benzimidazoles - Provided herein are drug delivery systems, such as self-nanoemulsifying drug delivery systems, self-emulsifying drug delivery systems and parenteral microemulsion formulations, suitable for parenteral or oral delivery to a subject. The drug delivery systems may comprise a benzimidazole derivative, e.g., mebendazole, an oil, a surfactant, a cosurfactant and a dipolar aprotic solvent in a microemulsion formulation. Also provided are methods for improving the bioavailability of a benzimidazole derivative during treatment of a pathophysiological condition by using a formulation combining a particular emulsion droplet diameter and ratio of the surfactant:cosurfactant therein, for increasing concentration and retention of a benzimidazole derivative in the lung via a parenterally administerable microemulsion with droplet size of about 35 nm to less than 100 nm and for defining hemolytically safe microemulsions of a benzimidazole derivative during a therapeutic treatment via a parenterally administerable microemulsion with a surfactant:cosurfactant content by weight of about 6% to 48%. | 02-19-2009 |
20100081672 | PH SENSITIVE MATRIX FORMULATION - The present invention provides formulations of therapeutic agents that benefit from a prolonged time of controlled release in the stomach and upper gastrointestinal (GI) tract, and from an enhanced drug exposure to the upper GI tract. The formulations of the invention comprise a therapeutic agent and one or more pH sensitive polymers that are designed for accelerated hydration, expansion, disintegration and dissolution at the higher pH of the upper GI tract, thereby, ensuring that any therapeutic agent that has not been released in the stomach is released in the upper GI tract, thus maximizing absorption of therapeutic agent that has a window of absorption located at the upper GI tract. | 04-01-2010 |
20100310611 | Parenteral and oral formulations of benzimidazoles - Provided herein are drug delivery systems, such as self-nanoemulsifying drug delivery systems, self-emulsifying drug delivery systems and parenteral microemulsion formulations, suitable for parenteral or oral delivery to a subject. The drug delivery systems may comprise a benzimidazole derivative, e.g., mebendazole, an oil, a surfactant, a cosurfactant and a dipolar aprotic solvent in a microemulsion formulation. Also provided are methods for improving the bioavailability of a benzimidazole derivative during treatment of a pathophysiological condition by using a formulation combining a particular emulsion droplet diameter and ratio of the surfactant:cosurfactant therein, for increasing concentration and retention of a benzimidazole derivative in the lung via a parenterally administerable microemulsion with droplet size of about 35 nm to less than 100 nm and for defining hemolytically safe microemulsions of a benzimidazole derivative during a therapeutic treatment via a parenterally administerable microemulsion with a surfactant:cosurfactant content by weight of about 6% to 48%. | 12-09-2010 |
20110038925 | INTRAVENOUS FORMULATIONS OF NEUROKININ-1 ANTAGONISTS - Pharmaceutical compositions for intravenous administration comprising the compound of Formula I | 02-17-2011 |
20120022032 | CORTICOSTEROID COMPOSITIONS AND METHODS OF TREATMENTS THEREOF - This invention relates to steroidal solutions for the preparation of medicaments and drug products useful for treating diseases of the upper and lower airway passages. Various embodiments of the present invention provide compositions, compositions and dosage forms with mometasone furoate in a dissolved state that are suitable for inhalation and can be used for the treatment of diseases of the upper and/or lower airway passages. | 01-26-2012 |
20160024092 | INTRAVENOUS FORMULATIONS OF NEUROKININ-1 ANTAGONISTS - Pharmaceutical compositions for intravenous administration comprising the compound of Formula I | 01-28-2016 |
Patent application number | Description | Published |
20090104256 | Methods of Treating Pulmonary Disorders with Liposomal Amikacin Formulations - Disclosed herein are methods of treating pulmonary disorders comprising administering to the patient an effective dose of a nebulized liposomal amikacin formulation for at least one treatment cycle, wherein: the treatment cycle comprises an administration period of 15 to 75 days, followed by an off period of 15 to 75 days; and the effective dose comprises 100 to 2500 mg of amikacin daily during the administration period. | 04-23-2009 |
20130089598 | METHOD OF TREATING PULMONARY DISORDERS WITH LIPOSOMAL AMIKACIN FORMULATIONS - Disclosed herein are methods of treating pulmonary disorders comprising administering to the patient an effective dose of a nebulized liposomal amikacin formulation for at least one treatment cycle, wherein: the treatment cycle comprises an administration period of 15 to 75 days, followed by an off period of 15 to 75 days; and the effective dose comprises 100 to 2500 mg of amikacin daily during the administration period. | 04-11-2013 |
20130136788 | METHOD FOR TREATING PULMONARY DISORDERS WITH LIPOSOMAL AMIKACIN FORMULATIONS - Disclosed herein are methods of treating pulmonary disorders comprising administering to the patient an effective dose of a nebulized liposomal amikacin formulation for at least one treatment cycle, wherein: the treatment cycle comprises an administration period of 15 to 75 days, followed by an off period of 15 to 75 days; and the effective dose comprises 100 to 2500 mg of amikacin daily during the administration period. | 05-30-2013 |
20150328232 | PROSTACYLIN COMPOSITIONS AND METHODS FOR USING THE SAME - The present invention relates to pharmaceutical compositions comprising a prostacyclin, a cationic compound, and a surfactant. Particulate compositions, including liposomal, solid nanoparticulate prostacyclin compositions, including treprostinil formulations comprising cationic compound and the surfactant are also described. The present invention also relates to a system comprising the pharmaceutical composition and an inhalation device. Methods for treating pulmonary hypertension and portopulmonary hypertension with the compositions and systems described herein are also provided. | 11-19-2015 |
20150328244 | METHODS FOR TREATING PULMONARY NON-TUBERCULOUS MYCOBACTERIAL INFECTIONS - Provided herein are methods for treating a pulmonary infection in a patient in need thereof, for example, a nontuberculous mycobacterial pulmonary infection for at least one treatment cycle. The method comprises administering to the lungs of the patient a pharmaceutical composition comprising a liposomal complexed aminoglycoside comprising a lipid component comprising electrically neutral lipids and an aminoglycoside. Administration comprises aerosolizing the pharmaceutical composition to provide an aerosolized pharmaceutical composition comprising a mixture of free aminoglycoside and liposomal complexed aminoglycoside, and administering the aerosolized pharmaceutical composition via a nebulizer to the lungs of the patient. The methods provided herein result in a change from baseline on the semi-quantitative scale for mycobacterial culture for a treated patient, and/or NTM culture conversion to negative during or after the administration period. | 11-19-2015 |
Patent application number | Description | Published |
20130030887 | CUSTOMER REWARD AND LOYALTY SYSTEM - Embodiments of the invention relate to systems, methods, and computer program products for implementing a customer loyalty rewards program by assigning point values to a customer's completion of certain activities, monitoring the customer's activities to determine when the customer has completed an activity, crediting the customer the assigned value of points for the completed activities, correlating points to one or more rewards and facilitating the exchange of rewards. | 01-31-2013 |
20130030888 | SYSTEM FOR ALLOWING CUSTOMERS TO CHOOSE REWARDS - Embodiments of the invention relate to systems, methods, and computer program products for allowing a customer to choose rewards as part of a customer incentive program by receiving a first customer input, wherein the first customer input is a characteristic of the customer, receiving a second customer input, wherein the second customer input is a category of reward in which the customer is interested, correlating the first customer input to a plurality of activities to be completed by the customer, correlating the second customer input to rewards to be provided to the customer for completing an activity, monitoring the customer's activities to determine when the customer has completed an activity and providing a reward to the customer corresponding to the completed activity. | 01-31-2013 |
20130030925 | CONTEXT-AWARE MOBILE BANKING SOLUTION - A context-aware mobile banking system determines a location of a user of the mobile device, identifies at least one product of interest to the user based at least in part on the determined location of the user, determines based on the determined product of interest, information corresponding to the product of interest, and presents the information corresponding to the product of interest to the user. In some embodiments, the system retrieves user budgeting information including a plurality of budget categories each having an associated budget amount and an associated remaining amount indicating an amount remaining in from the budget amount, determines a budget category from the plurality of budget categories associated with the product of interest, and determines the budget amount and remaining amount associated with the determined budget category. The system then may present information corresponding to the remaining amount and the budget amount to the user. | 01-31-2013 |
20130030994 | BUDGET MONITOR, ALERT, AND BILL PAYMENT FACILITATION SYSTEM - A budget monitoring, alerting and bill payment facilitation system retrieves macro-budgeting information associated with a user, where the macro-budgeting information includes a plurality of budget categories each having an associated budget amount corresponding to a macro time period, divides the budget amount corresponding to the macro time period into a plurality of micro budget amounts corresponding to a plurality of micro time periods, and presents, to the user by a mobile device, micro-budgeting information corresponding to at least one of the plurality of micro budget amounts or its corresponding micro time period. In some embodiments, the system retrieves user data, determines the user may be experiencing a life event based on the user data, where the micro-budgeting information is based on the determination that the user may be experiencing a life event, and confirms that the user is experiencing a life event. | 01-31-2013 |
Patent application number | Description | Published |
20110287095 | Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans - Methods for producing stabilized solid dosage form pharmaceutical compositions are provided. In particular, methods for preparing protected granules containing morphinans, and solid dosage form pharmaceutical compositions produced using the morphinan-protected granules are provided. | 11-24-2011 |
20140105977 | GASTRIC RETENTIVE EXTENDED RELEASE PHARMACEUTICAL COMPOSITIONS - The present disclosure provides extended release pharmaceutical compositions comprising an opioid and an additional active pharmaceutical ingredient, wherein the composition exhibits gastric retentive properties which are achieved by a combination of a physical property of the composition and release of the opioid, wherein upon administration to a subject, the composition has at least one pharmacokinetic parameter that differs by less than about 30% when the subject is in a fasted state as compared to a fed state. | 04-17-2014 |
20140170217 | COMBINATION COMPOSITION COMPRISING OXYCODONE AND ACETAMINOPHEN FOR RAPID ONSET AND EXTENDED DURATION OF ANALGESIA - The present disclosure provides an extended release pharmaceutical composition comprising oxycodone and acetaminophen that provides a rapid onset of analgesia, and reduced levels of acetaminophen near the end of the dosing interval. Also provided are methods for reducing the risk of acetaminophen-induced hepatic damage in a subject being treated with an acetaminophen containing composition, as well as methods for treating pain in a subject in need thereof. | 06-19-2014 |
20140288113 | Extended Release Compositions Comprising Hydrocodone And Acetaminophen For Rapid Onset And Prolonged Analgesia That May Be Administered Without Regard To Food - The present disclosure provides an extended release pharmaceutical composition comprising hydrocodone and acetaminophen that provides a rapid onset of analgesia, and reduced levels of acetaminophen near the end of the dosing interval. Also provided are methods for reducing the risk of acetaminophen-induced hepatic damage in a subject being treated with an acetaminophen containing composition, as well as methods for treating pain in a subject in need thereof. | 09-25-2014 |
20140294956 | GASTRIC RETENTIVE EXTENDED RELEASE PHARMACEUTICAL COMPOSITIONS - The present disclosure provides extended release pharmaceutical compositions comprising an opioid and an additional active pharmaceutical ingredient, wherein the composition exhibits gastric retentive properties which are achieved by a combination of a physical property of the composition and release of the opioid, wherein upon administration to a subject, the composition has at least one pharmacokinetic parameter that differs by less than about 30% when the subject is in a fasted state as compared to a fed state. | 10-02-2014 |
20140378498 | Tamper Resistant Composition Comprising Hydrocodone And Acetaminophen For Rapid Onset And Extended Duration Of Analgesia - The present disclosure provides an extended release pharmaceutical composition comprising hydrocodone and acetaminophen that provides a rapid onset of analgesia, and reduced levels of acetaminophen near the end of the dosing interval. Also provided are methods for reducing the risk of acetaminophen-induced hepatic damage in a subject being treated with an acetaminophen containing composition, as well as methods for treating pain in a subject in need thereof. | 12-25-2014 |
20150246034 | PHARMACEUTICAL COMPOSITIONS FOR EXTENDED RELEASE OF OXYCODONE AND ACETAMINOPHEN RESULTING IN A QUICK ONSET AND PROLONGED PERIOD OF ANALGESIA - The present disclosure provides extended release pharmaceutical compositions comprising oxycodone and acetaminophen that produce a quick initial onset of analgesia, yet, maintain analgesia for about 12 hours after administration of the composition to a subject in need thereof. The pharmaceutical compositions disclosed herein also reduce the levels of acetaminophen in a subject's blood near the end of the dosing interval because the acetaminophen released by the pharmaceutical composition is being eliminated by a subject's body faster than it is being absorbed. | 09-03-2015 |