Gruber, AT
Alois Gruber, Buermoos AT
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20110290180 | APPARATUS FOR IMPREGNATING WEB-LIKE MATERIALS WITH THERMALLY CURABLE IMPREGNATING RESIN - An apparatus for impregnating web material with thermally curable impregnating resin, The apparatus includes an impregnating trough in which the web material is brought into contact with the impregnating resin and an inlet line which leads to the impregnating trough and through which the impregnating resin is introduced into the impregnating trough. The apparatus also includes a heating device structured and arranged for heating the impregnating resin, wherein the heating device is associated with the inlet line and heats the impregnating resin in the inlet line. | 12-01-2011 |
Alois Gruber, Burmoos AT
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20110192048 | Method and Device for Drying and Precondensing Impregnation Products which are Constituted of a Resin-Bonded Film-Type Web Material; Melamine-Free Impregnation Product - In a process and a mechanism ( | 08-11-2011 |
Andreas Gruber, Maria Buch - Feistritz AT
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20110249926 | Seal for Rolling Bearing, in Particular for Rolling Bearing Used in a Wind Turbine - The rolling bearing comprises an inner ring | 10-13-2011 |
20130209010 | FRICTION DEVICE FOR A BEARING ASSEMBLY, BEARING AND BEARING ASSEMBLY COMPRISING SUCH A FRICTION DEVICE - A friction device ( | 08-15-2013 |
20130322803 | ROLLING ELEMENT BEARING HAVING REPLACEABLE SEAL - A rolling-element bearing includes a first bearing ring ( | 12-05-2013 |
20140023303 | SEAL FOR ROLLING BEARING USED IN A WIND TURBINE - The rolling bearing comprises an inner ring | 01-23-2014 |
Bernadette Gruber, Vienna AT
Patent application number | Description | Published |
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20120315650 | DETECTION OF CIRCULATING ADAMTS13-ANTIBODY COMPLEXES - The present invention relates to methods and means for detecting ADAMTS13 immune complexes in a sample. The methods include the steps of capturing and labelling immune complexes of anti-ADAMTS13 antibodies. Capturing and labelling may be achieved by two different binding units targeting the immune complexes. The invention further relates to diagnosing diseases associated with immunologic ADAMTS13 dysfunction like TTP (thrombotic thrombocytopenic purpura). | 12-13-2012 |
Bernhard Gruber, Gratwein AT
Patent application number | Description | Published |
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20080258872 | Method of Operating a Rfid System - The invention relates to a method of operating a RFID system comprising at least one reader ( | 10-23-2008 |
20100015925 | DEVICE FOR AND METHOD OF CHARACTERIZING AN OBJECT - A device for characterizing an object ( | 01-21-2010 |
20100090804 | CONTACTLESS TRANSMISSION ELEMENT AND METHOD OF CHARACTERIZING THE SAME - A method of characterizing a contactless transmission element ( | 04-15-2010 |
Christian Gruber, Weiz AT
Patent application number | Description | Published |
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20150302142 | DETERMINING NOVEL ENZYMATIC FUNCTIONALITIES USING THREE-DIMENSIONAL POINT CLOUDS REPRESENTING PHYSICO CHEMICAL PROPERTIES OF PROTEIN CAVITIES - The invention relates to a method for determining catalophores including the steps of creating a point cloud database for target protein structures; creating a query point cloud; and searching said database with said query to thereby identify one or more catalophores. | 10-22-2015 |
Christian Gruber, Graz AT
Patent application number | Description | Published |
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20090098623 | PROCESS FOR THE RACEMIZATION OF OPTICALLY ACTIVE SECONDARY ALCOHOLS WITH THE USE OF ALCOHOL DEHYDROGENASE - A method for racemizing optically active secondary alcohols by incubating these alcohols with at least one alcohol dehydrogenase of the E.C. 1.1.1. class. | 04-16-2009 |
20110070630 | METHOD FOR DERACEMIZATION OF ENANTIOMER MIXTURES - The invention relates to a process for enzymatic deracemization of enantiomer mixtures of secondary alcohols by a combination of oxidation and reduction reactions by means of stereoselective alcohol dehydrogenases and the cofactors thereof, wherein one enantiomer of an optically active secondary alcohol is in a formal sense selectively oxidized to the corresponding ketone, which is subsequently reduced selectively to the optical antipode, while the reduced form of the cofactor is provided for the reduction reaction by means of an additional enzyme, characterized in that two alcohol dehydrogenases with opposite stereoselectivity and different cofactor selectivity and the two corresponding, different cofactors are used for the oxidation and reduction reactions, and the oxidized and reduced cofactors are interconverted in a parallel enzymatic reaction with the additional enzyme, the direction of the deracemization toward one of the two enantiomers being controllable by the selection of the two alcohol dehydrogenases or using the selectivity difference of the additional enzyme for the two cofactors. | 03-24-2011 |
Christian Werner Gruber, Vienna AT
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20140369930 | CYCLOTIDES AS IMMUNOSUPPRESSIVE AGENTS - The present invention relates to a pharmaceutical composition comprising a cyclotide for use in immune suppression as well as to a method for immune suppression comprising the step of administering an effective amount of a pharmaceutical composition comprising such a cyclotide to a subject in need thereof. The present invention also relates to a pharmaceutical composition comprising a cyclotide for use in treating or preventing a disorder selected from the group consisting of (i) an autoimmune disorder; (ii) a hypersensitivity disorder; and (iii) a lymphocyte-mediated inflammation. Likewise, the present invention also relates to a method for treating or preventing a disorder selected from the group consisting of (i) an autoimmune disorder; (ii) a hypersensitivity disorder; and (iii) a lymphocyte-mediated inflammation. The present invention further relates to a method of screening for and/or selecting an immunosuppressive cyclotide or a mutation which results in a mutated cyclotide having an induced or enhanced immunosuppressive activity. The present invention further relates to a method of producing an immunosuppressive cyclotide or an immunosuppressive pharmaceutical composition. The present invention further relates to a mutated cyclotide having immunosuppressive activity and a pharmaceutical composition comprising the same. | 12-18-2014 |
20160039882 | CYCLOTIDES AS IMMUNOSUPPRESSIVE AGENTS - The present invention relates to a pharmaceutical composition comprising a cyclotide for use in immune suppression as well as to a method for immune suppression comprising the step of administering an effective amount of a pharmaceutical composition comprising such a cyclotide to a subject in need thereof. The present invention also relates to a pharmaceutical composition comprising a cyclotide for use in treating or preventing a disorder selected from the group consisting of (i) an autoimmune disorder; (ii) a hypersensitivity disorder; and (iii) a lymphocyte-mediated inflammation. Likewise, the present invention also relates to a method for treating or preventing a disorder selected from the group consisting of (i) an autoimmune disorder; (ii) a hypersensitivity disorder; and (iii) a lymphocyte-mediated inflammation. The present invention further relates to a method of screening for and/or selecting an immunosuppressive cyclotide or a mutation which results in a mutated cyclotide having an induced or enhanced immunosuppressive activity. The present invention further relates to a method of producing an immunosuppressive cyclotide or an immunosuppressive pharmaceutical composition. The present invention further relates to a mutated cyclotide having immunosuppressive activity and a pharmaceutical composition comprising the same. | 02-11-2016 |
Christina Gruber, Bad Vigaun AT
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20150250901 | RNA TRANS-SPLICING MOLECULE (RTM) FOR USE IN THE TREATMENT OF CANCER - The present invention pertains to a novel pre-mRNA trans-splicing molecule (RTM) comprising a binding region which is complementary to a pre mRNA of a tumor associated gene, and a coding domain which encodes for a suicide gene. Specific embodiments of the present invention relate to RTMs which mediate trans-splicing of a suicide gene, such as thymidine kinase from herpes simplex virus (HSV-tk), with the pre mRNA of the squamous cell carcinoma associated gene solute carrier organic anion transporter family member 1B3 (SLCO1B3). The invention provides RTMs which selectively kill cells expressing SLCO1B3 and which are thus useful in the treatment of cancer, specifically squamous cell carcinoma associated with epidermolysis bullosa. Also provided are methods, kits and pharmaceutical compositions relating to the RTMs in accordance to the invention. | 09-10-2015 |
Christoph Gruber, Wenberg AT
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20150221735 | Method of Forming a Trench Using Epitaxial Lateral Overgrowth and Deep Vertical Trench Structure - In one aspect, a method of forming a trench in a semiconductor material includes forming a first dielectric layer on a semiconductor substrate. The first dielectric layer includes first openings. An epitaxial layer is grown on the semiconductor substrate by an epitaxial lateral overgrowth process. The first openings are filled by the epitaxial layer and the epitaxial layer is grown onto adjacent portions of the first dielectric layer so that part of the first dielectric layer is uncovered by the epitaxial layer and a gap forms between opposing sidewalls of the epitaxial layer over the part of the first dielectric layer that is uncovered by the epitaxial layer. The gap defines a first trench in the epitaxial layer that extends to the first dielectric layer. | 08-06-2015 |
Christoph Gruber, Hippach AT
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20150258479 | Filtration System - A filtration system for separating accompanying substances, present in liquid, droplet or mist form, from a gaseous material stream, comprising | 09-17-2015 |
Daniel Gruber, St. Andrae AT
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20130222168 | SWITCHED CURRENT-CELL WITH INTERMEDIATE STATE - Representative implementations of devices and techniques provide digital-to-analog conversion of signals while minimizing switching related errors. Digital to analog converter (DAC) cells may be arranged to include one or more operating states in addition to binary output states, and may employ a switching technique to “dump” the DAC cell between binary outputs. Further, an array of DAC cells may include a partial set of redundant DAC cells for implementation of the switching technique. | 08-29-2013 |
Daniel Gruber, St. Andra AT
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20110089994 | Threshold Voltage Modification Via Bulk Voltage Generator - The present disclosure relates to threshold voltage modification via a voltage generator connected to bulk nodes of transistors. | 04-21-2011 |
Florian Gruber, Wien AT
Patent application number | Description | Published |
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20100119613 | PROCESS TO ACTIVATE EXTRACTS DERIVED FROM LIVING ORGANISMS USING LONG WAVE UV IRRADIATION AND COMPOSITIONS COMPRISING SAID ACTIVATED EXTRACT - The present invention relates to a method for producing an extract which is capable of inducing an antioxidant stress response comprising the step of treating an extract from organic material with UV light, said extract being derived from a non-mammalian cell or a non-mammalian organism and said cell or organism being capable of synthesizing polyunsaturated fatty acids. Furthermore, an extract capable of inducing an antioxidant stress response produced in accordance with the inventive methods, in particular an extract capable of inducing an antioxidant stress response for the preparation of a cosmetic composition is disclosed. The present invention also relates to a cosmetic composition comprising the inventive extract obtainable by the method provided herein. | 05-13-2010 |
Franz Gruber, Vienna AT
Patent application number | Description | Published |
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20100124748 | METHOD FOR THE SPECIFIC DETECTION OF LOW ABUNDANCE RNA SPECIES IN A BIOLOGICAL SAMPLE - The present invention relates to a method and a kit for the detection of low abundance RNA species in a biological sample and to a method and a kit for the detection of a | 05-20-2010 |
20130004958 | METHOD FOR THE SPECIFIC DETECTION OF LOW ABUNDANCE RNA SPECIES IN A BIOLOGICAL SAMPLE - The present invention relates to a method and a kit for the detection of low abundance RNA species in a biological sample and to a method and a kit for the detection of a mycoplasma contamination in a biological sample. | 01-03-2013 |
Friedrich Gruber, Hippach AT
Patent application number | Description | Published |
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20090158952 | Laser ignition apparatus - A laser ignition apparatus including at least two laser light generating devices and a common optical coupling-in means for coupling laser light from the at least two laser light generating devices into a combustion chamber of a combustion machine, wherein the at least two laser light generating devices are so arranged that laser light given off by the laser light generating devices in the operating condition impinges on the optical coupling-in means and/or issues from the optical coupling-in means in parallel displaced relationship or at an angle to each other. A method of igniting a fuel/air mixture in a combustion chamber of a combustion machine. | 06-25-2009 |
20090159031 | Laser ignition apparatus - An apparatus for the ignition of a fuel/air mixture in the combustion chamber of a combustion machine, wherein the combustion chamber has at least one inlet valve and at least one outlet valve, wherein there are further provided a laser light generating device for giving off laser light and a combustion chamber window for coupling the laser light into a combustion chamber of the combustion machine, wherein there is provided at least one fluid feed means which is separate from the inlet valve or valves and with which a fluid can be caused to flow at least on to regions of the surface of the combustion chamber window or between the combustion chamber window and the focal point of the laser light. | 06-25-2009 |
20090159032 | Laser Ignition apparatus - Apparatus for coupling laser light into a combustion chamber of a combustion engine including a combustion chamber window and a structural element, wherein the combustion chamber window is releasably fixable to the structural element, wherein there is provided an optical window which is arranged at the structural element and is at least region-wise covered by the combustion chamber window. | 06-25-2009 |
20100011721 | AIR FILTER FOR A COMBUSTION MACHINE - An air filter for a combustion machine including a housing with a flow passage and a filter insert, wherein said filter insert subdivides the flow passage into an intake flow passage with an air inlet opening and into a discharge flow passage with an air outlet opening, wherein the filter insert has an air inlet surface which extends at least region-wise over the length of the filter insert along the air flow direction, wherein said filter insert has at least two successive filter elements, wherein the outside diameter or diameters of said filter elements, is or are different. | 01-21-2010 |
20100275891 | INTERNAL COMBUSTION ENGINE - A method for operating an internal combustion engine, comprising a compression device, an air/fuel mixture being compressed in the compression device, the air/fuel mixture ratio λ | 11-04-2010 |
20110100322 | DEVICE FOR IGNITING A FUEL/AIR MIXTURE - The invention relates to a device for igniting a fuel/air mixture in the combustion chamber of an internal combustion engine, comprising an electrode which is connected to a voltage source and extends into a precombustion chamber, wherein the precombustion chamber is separated at least in some regions from the combustion chamber by a wall, wherein a control device or a regulating device is provided which controls the voltage supply to the electrode such that a corona discharge is carried out in the precombustion chamber, wherein the wall has at least one opening for exchanging fluids between the combustion chamber and precombustion chamber, wherein a fluid inlet opens into the precombustion chamber. | 05-05-2011 |
20110185996 | Flow Protection Device on a Laser Spark Plug for Improving the Ignition Behavior - A laser spark plug, in particular for an internal combustion engine, having an arrangement or structure for coupling, especially focusing, laser radiation in or on an ignition point, including an arrangement or structure for influencing a fluid flow disposed in an end region of the laser spark plug on the side of the combustion chamber, which constitute an essentially sleeve-shaped extension of the laser spark plug in the direction of the combustion chamber, in which the arrangement or structure for influencing the fluid flow is configured to influence the fluid flow in the region of the ignition point. | 08-04-2011 |
20110297121 | SPARK PLUG WITH A LASER DEVICE IN A PRECHAMBER - A spark plug is described, for an internal combustion engine, having a prechamber for accommodating an ignitable medium, and having a laser device for applying laser radiation to an ignition point situated in the prechamber. The laser device has a laser-active solid body having a passive Q-switch. | 12-08-2011 |
20120180744 | INTERNAL COMBUSTION ENGINE IGNITION DEVICE - The invention relates to an arrangement comprising an internal combustion engine ignition device having a spark plug and a spark plug seat in which the spark plug can be fastened in a fastening zone, and a cylinder head in which the spark plug is or can be mounted via the spark plug seat, the cylinder head having a cylinder head cooling cavity. The spark plug seat comprises a temperature control medium chamber which is separate from the cylinder head cooling cavity and has a medium feed line and a medium discharge line, the temperature control medium chamber and the cylinder head cooling cavity being connected to separate medium temperature control devices and forming separate medium systems. | 07-19-2012 |
20120210969 | LASER SPARK PLUG FOR AN INTERNAL COMBUSTION ENGINE - The invention relates to a laser spark plug, comprising a laser light-producing device ( | 08-23-2012 |
20130055985 | METHOD FOR OPERATING AN INTERNAL COMBUSTION ENGINE - Method for operating an internal combustion engine, in particular a gas spark-ignition engine with prechamber ignition, wherein the prechamber is supplied from the outside with a gas mixture as a scavenging gas whose CO | 03-07-2013 |
20130174555 | ELECTRIC POWER STATION - The invention relates to a power station comprising at least two generators ( | 07-11-2013 |
20130181461 | POWER PLANT UNIT - The invention relates to a power plant unit ( | 07-18-2013 |
20130309142 | CATALYTIC CONVERTER ARRANGEMENT FOR AN EXHAUST-GAS CLEANING DEVICE OF AN INTERNAL COMBUSTION ENGINE - An exhaust-gas cleaning device for an internal combustion engine has a catalytic converter arrangement. The catalytic converter arrangement includes, along the flow direction, a plurality of catalytically active regions which are, in particular, independent of one another. A heat dissipation device includes a heat absorbing device and one heat sink. The heat absorbing device is provided between at least two catalytically active regions. The heat absorbing device is connected to the heat sink. The exhaust-gas cleaning device includes a plurality of catalytic converter arrangements, an, in particular tubular, inner housing with a housing cover, and an outer housing which encloses the inner housing. The inner housing has a longitudinal axis, and the catalytic converter arrangements are arranged separately from one another on the housing cover of the inner housing. | 11-21-2013 |
20140083391 | PRE-CHAMBER SYSTEM FOR AN INTERNAL COMBUSTION ENGINE - A pre-chamber system for an internal combustion engine, in particular for a gas engine, comprising a pre-chamber volume in which an ignitable fuel-air mixture can be fired—in particular by an ignition device which can be arranged at the pre-chamber system—, wherein the pre-chamber system is provided with a flow transfer passage by which the pre-chamber volume can be connected to a main combustion chamber of the internal combustion engine, wherein the pre-chamber volume includes an ignition region and a flow transfer region which is at least portion-wise delimited from the ignition region by an intermediate wall, wherein the fuel-air mixture can be fired in the ignition region and the flow transfer passage opens into the flow transfer region and there is provided an air feed passage, wherein—preferably compressed—air can be fed to the flow transfer region by way of the air feed passage. | 03-27-2014 |
20140109845 | INTERNAL COMBUSTION ENGINE REFORMER INSTALLATION - An internal combustion engine reformer installation comprising | 04-24-2014 |
20140109853 | INTERNAL COMBUSTION ENGINE-REFORMER INSTALLATION - A method of operating an internal combustion engine-reformer installation having an internal combustion engine and a reformer, includes predetermining at least one parameter of the internal combustion engine, calculating a desired amount of fuel for the reformer on the basis of the at least one parameter, feeding the desired amount of fuel to the reformer, reforming fuel to give a synthesis gas in the reformer, and feeding the synthesis gas to the internal combustion engine. A synthesis gas pressure of the synthesis gas downstream of the reformer is measured, and the synthesis gas pressure is taken into consideration when calculating the desired amount of fuel. | 04-24-2014 |
20140109855 | LASER SPARK PLUG - A laser spark plug for an internal combustion engine, in particular for a gas engine, comprising a laser crystal integrated into the laser spark plug and a combustion chamber optical means, wherein laser light pulses issuing from the laser crystal can be coupled by way of the combustion chamber optical means into a combustion chamber of the internal combustion engine, an optical laser light sensor being integrated into the laser spark plug, wherein the combustion chamber optical means is provided with a reflection surface which faces towards the laser light sensor—and is preferably curved—and is provided with a reflective mirroring, wherein at least a part of a laser light reflected at the reflection surface during the duration of a laser light pulse can be detected by the laser light sensor. | 04-24-2014 |
20140109866 | INTERNAL COMBUSTION ENGINE - An internal combustion engine includes one main combustion chamber for the combustion of a first combustion mixture, one pre-combustion chamber for each respective main combustion chamber for the combustion of a second combustion mixture, a first fuel gas mixer for providing the first combustion mixture, a second fuel gas mixer for providing the second combustion mixture, an air feed line and a synthesis gas feed line, a first mixture line connected to the first fuel gas mixer and the main combustion chamber, and a second mixture line connected to the second fuel gas mixer and the pre-combustion chamber. The first fuel gas mixer is connected to the synthesis gas feed line for the admixing of synthesis gas, and an open or closed loop control device is provided for open or closed loop controlling mixing ratios of fuel, air and synthesis gas in the first combustion mixture and/or second combustion mixture. | 04-24-2014 |
20140116362 | METHOD FOR OPERATING A STATIONARY POWER GENERATING PLANT - A method for operating a stationary power generating plant, comprising a gas engine with at least one pre-chamber and at least one main combustion chamber, wherein the stationary power generating plant is fed a gas stream—in particular a substantially continuous gas stream—which comprises a hardly inflammable gas, wherein the gas stream is divided in the stationary power generating plant into a main stream and a partial stream, wherein the main stream is fed to the at least one main combustion chamber and wherein the partial stream is treated to increase its inflammability and is fed to the at least one pre-chamber of the gas engine, and also a stationary power generating plant with a gas engine. | 05-01-2014 |
20140216029 | INTERNAL COMBUSTION ENGINE, IN PARTICULAR A STATIONARY GAS ENGINE, COMPRISING A COMBUSTION CHAMBER - An internal combustion engine, in particular a stationary gas engine, includes a combustion chamber to which a propellant can be fed from a first propellant source via a combustion chamber pipe, and a pre-combustion chamber to which a flushing gas can be fed via a flushing gas pipe. A flushing gas mixer , in which a propellant to be fed via a propellant pipe from the first propellant source or from a second propellant source, and a synthesis gas to be fed via a synthesis gas pipe, can be mixed is provided. A mixer outlet opens into the flushing gas pipe, and the synthesis gas can be generated by a reformer to which a fuel can be fed from a fuel source via a reformer feed pipe. The reformer outlet of the reformer opens into the synthesis gas pipe, and a cooling device for cooling the synthesis gas is provided. | 08-07-2014 |
20140245999 | METHOD FOR COOLING COMPRESSED CHARGE AIR OF A TURBOCHARGED INTERNAL COMBUSTION ENGINE - The invention relates to a method for cooling compressed charge air of a turbocharged internal combustion engine, wherein starting from a compression temperature the compressed charge air is cooled in a first cooling device to a first lowered temperature and in a subsequent second cooling device is cooled to a second lowered temperature which is lower than the first lowered temperature, wherein after the second cooling device the compressed charge air is cooled in a third cooling device to a third lowered temperature which is lower than the second lowered temperature, wherein the cooling or the compressed charge air in the third cooling device is effected only intermittently during operation of the internal combustion engine. | 09-04-2014 |
20140290613 | LASER SPARK PLUG - A laser ignition plug, comprising a pumped light source and a longitudinally pumped laser resonator, which are each arranged in the housing of the laser ignition plug, characterized by a cooling air inlet, a cooling air outlet and a cooling region connecting the cooling air inlet with the cooling air outlet, wherein the cooling region is surrounding the pumped light source at least in certain sectors. | 10-02-2014 |
20160097316 | METHOD FOR OPERATING A COMPRESSION IGNITION ENGINE - A method for operating a compression ignition engine includes forming a combustible mixture by mixing generally homogeneously a first fuel and air and introducing this mixture into the at least one cylinder, compressing the combustible mixture with the piston in a compression stroke, injecting a second fuel to the combustible mixture at an injection-time of the second fuel during the compression stroke but before start of combustion, and continuing the compression stroke until combustion starts at those locations in the at least one cylinder where concentration of the second fuel is highest and/or the temperature of the mixture is the highest. Emission of the cylinder and/or mechanical stress of the cylinder caused by the combustion are monitored, and if emissions and/or mechanical stress are above respective predetermined thresholds, individually for the cylinder, the amount and/or the timing of the second fuel injected, and/or temperature of the cylinder charge is changed. | 04-07-2016 |
20160097338 | METHOD FOR OPERATING AN INTERNAL COMBUSTION ENGINE - A method of operating a compression ignition engine uses an engine having a cylinder and a piston moveable in the cylinder. The method includes forming a combustible mixture by mixing generally homogeneously a first fuel and air and introducing this mixture into the at least one cylinder, and compressing the combustible mixture with the piston in a compression stroke. During the compression stroke but before start of combustion, a second fuel is added to the combustible mixture, thus creating a cylinder charge, the second fuel being easier to autoignite than the first fuel. The compression stroke is continued until combustion starts at those locations in the cylinder where concentration of the second fuel and/or temperature of the mixture is highest. A temperature of the cylinder charge and/or the amount of second fuel added to the combustible mixture is chosen such that a desired duration of combustion can be achieved. | 04-07-2016 |
Gerald Gruber, Nussdorf AT
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20110185724 | Two-Stage Exhaust Gas Turbocharging Arrangement for an Internal Combustion Engine - A two-stage exhaust gas turbocharger for an internal-combustion engine having an exhaust manifold is provided. In the exhaust gas flow direction a first high-pressure turbocharger and a second high-pressure turbocharger are arranged parallel to one another and a low-pressure turbocharger is arranged in series behind the latter. The two high-pressure turbine housings can be arranged on the exhaust manifold on one side and the low-pressure turbine housing can be arranged on the exhaust manifold on the other side. The exhaust gas coming from the high-pressure turbine housings is guided through a flow duct in or on the exhaust manifold to the low-pressure turbine housing. By way of this construction of the two-stage exhaust gas turbocharging, a compact construction is achieved resulting in cost savings. | 08-04-2011 |
Gerhard Gruber, Wien AT
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20100159023 | METHOD FOR STABILISING BLOOD PLASMA COMPONENTS IN A LYOPHILISATE - Process for the stabilization of blood plasma components in a lyophilizate, wherein | 06-24-2010 |
20130118025 | LYOPHILISATION TARGETING DEFINED RESIDUAL MOISTURE BY LIMITED DESORPTION ENERGY LEVELS - A process of freeze drying of an essentially aqueous solution comprising at least one first step having a first temperature and pressure level (i.e. primary drying phase) and at least one second step having a second temperature and pressure level (i.e. secondary drying phase) following the first step, wherein in the secondary drying phase limited desorption energy input is applied. | 05-16-2013 |
Gerhard Gruber, Vienna AT
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20140051839 | Process for Reduction and/or Removal of FXI and FXIa from Solutions Containing said Coagulation Factors - A process for reduction and/or removal of FXI and FXIa from a source solution containing said coagulation factors and as main components immunoglobulins comprising the following steps: | 02-20-2014 |
Heinrich Gruber, Wien AT
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20080277814 | Polymerizable compositions with acylgermanium compounds - Composition with at least one polymerizable binder and at least one polymerization initiator, which contains at least one acylgermanium compound according to general Formula (I), | 11-13-2008 |
20080287565 | Polymerized Molded Body - The invention relates to polymerizable compositions which comprise 10-80% by weight of a reactive diluent based on acrylic acid or methacrylic acid derivatives, and 10-50% by weight of a monomer of the indicated chemical formula which is liquid or which can be dissolved in the formulation. The formula may contain amino acid residues or peptide sequences, especially such that are specific of the collagen. These structural elements allow the enzymatic degradation of the polymers of the inventive composition. | 11-20-2008 |
20080300383 | Methods for the Production of Polymer Carrier Materials Based on Carbon Hydrate-Bis(Meth)Acryl-Amides - The invention relates to methods for the production of polymer carrier materials for solid phase synthesis, particularly for peptide synthesis. (Meth)acrylamide derivatives based on carbon hydrates, which can also contain other protective groups, are polymerized by means of suspension polymerization in an aqueous phase, optionally with the addition of pore-forming additives, and subsequently the protective groups are fully or partially cleaved. It is thus possible to obtain polymer carriers whose morphology (particle size, porosity), degree of cross-linking and swelling capability in aqueous and organic media can be adjusted in a targeted manner and whose reactive groups offer multiple opportunities for the immobilization of anchor groups and protective groups. The hydroxyl groups of the polymer carrier can be activated according to usual methods of solid phase synthesis. | 12-04-2008 |
20100303804 | COMPOSITION THAT CAN BE CURED BY POLYMERISATION FOR THE PRODUCTION OF BIODEGRADABLE, BIOCOMPATIBLE, CROSS-LINKABLE POLYMERS ON THE BASIS OF POLYVINYL ALCOHOL - The present invention relates to a polymerization-curable composition for the preparation of biodegradable, biocompatible, cross-linked polymers on the basis of polyvinyl alcohol comprising: 5 to 100% by weight of (a) vinyl ester monomer(s) of one of the general formulas (I) to (III): | 12-02-2010 |
Johann Gruber, Hohenzell AT
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20090262345 | IMMERSION PROBE FOR LIPS APPARATUSES - The invention relates to an immersion probe ( | 10-22-2009 |
Josef Gruber, St. Ruprecht An Der Raab AT
Patent application number | Description | Published |
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20130135085 | TRANSPONDER UNIT, SYSTEM AND METHOD FOR CONTACTLESS DATA TRANSMISSION - In various embodiments, a transponder unit for the contactless transmission of modulated data to a reader is provided. The transponder unit may include: a clock generator configured to generate a clock signal and to synchronize the clock signal in a synchronization mode, on the basis of a signal received from the reader; and a modulator configured to take the clock signal from the clock generator as a basis for modulating data; wherein the modulator is configured to send a signal for starting the synchronization mode to the clock generator. | 05-30-2013 |
20140313092 | ANTENNA ARRANGEMENT, COMMUNICATION APPLIANCE AND ANTENNA STRUCTURE - In various embodiments, an antenna arrangement is provided. The antenna arrangement may include at least one integrated circuit; at least one loop antenna that is coupled to the integrated circuit and that forms a loop antenna region; at least one antenna that is coupled to the integrated circuit and that has a magnet core; wherein at least one portion of the magnet core is arranged above a portion of the loop antenna region; wherein the portion of the magnet core overlaps the portion of the loop antenna region; or wherein the portion of the magnet core does not overlap the portion of the loop antenna region. | 10-23-2014 |
20140341327 | TRANSPONDER UNIT, SYSTEM AND METHOD FOR CONTACTLESS DATA TRANSMISSION - A transponder unit for the contactless transmission of modulated data to a reader is provided. The transponder unit includes a clock generator configured to generate a clock signal and to synchronize the clock signal in a synchronization mode, on the basis of a signal received from the reader, and a modulator, the modulator configured to modulate data on the basis of the clock signal from the clock generator. The modulator is configured to generate a modulation pause by masking out at least one modulation component, the modulation component being smaller than a modulation pulse. The modulator is further configured to send the signal for starting the synchronization mode to the clock generator during this modulation pause. | 11-20-2014 |
20150263789 | CIRCUIT ARRANGEMENT - A circuit arrangement is provided, having an antenna, a first circuit coupled to the antenna and configured to receive an antenna signal, which contains first data, and to process the antenna signal, as a result of which it produces a processed antenna signal having a different voltage level than that of the antenna signal. The first data are data transmitted from a communication device to the arrangement. The arrangement further includes a second circuit coupled to the first circuit via a wire-based interface. The first circuit is configured to transmit the processed antenna signal to the second circuit by a first channel of the wire-based interface and the second circuit is configured to transmit second data to the first circuit by a second channel of the wire-based interface. The first channel and the second channel are different. The second data are configuration data for configuring the first circuit. | 09-17-2015 |
20150333397 | COMMUNICATION MODULE - Various embodiments provide a communication module having a carrier, a loop antenna, a modulation circuit which is coupled to the loop antenna and is configured to modulate or demodulate signals which are received or transmitted using the loop antenna, and an impedance matching circuit for matching the impedance of the loop antenna to the input impedance of the modulation circuit. The modulation circuit and the impedance matching circuit are arranged inside the loop antenna on or in the carrier. | 11-19-2015 |
Josef Gruber, Mettmach AT
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20150047948 | FACILITY FOR REPAIRING FLAWS IN PIECES OF WOOD - A facility for repairing flaws in pieces of wood ( | 02-19-2015 |
Josef Gruber, St. Ruprecht AT
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20160111787 | HYBRID ANTENNA, ANTENNA ARRANGEMENT AND METHOD FOR MANUFACTURING AN ANTENNA ARRANGEMENT - According to one embodiment, a hybrid antenna is described comprising a plurality of windings wherein each winding comprises a loop antenna portion arranged in a plane and a ferrite antenna portion arranged at least partially outside of the plane. | 04-21-2016 |
Josef Gruber, Haidershofen AT
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20080313946 | Rod Magazine for a Firearm - Rod magazine for a firearm, having a channel for holding cartridges in a stack, and having a feed for feeding the stack to a channel end which is clasped by magazine lips, which hold the top cartridge in the stack back in the channel direction, but allow its movement approximately transversely with respect to the channel direction beyond the rod magazine, with the channel being equipped with guide strips, which run in the channel direction, for the shoulders of the cartridges, and with the guide strips projecting beyond the channel end and into the movement path, which is located in front of the magazine lips, of the top cartridge. | 12-25-2008 |
Karl Gruber, Graz AT
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20100041110 | R-Hydroxynitrile Lyases Having Improved Substrate Acceptance and the Use Thereof - R-hydroxynitrile lyases having an improved substrate acceptance, increased activity and increased selectivity, in which there is replacement in the amino acid sequence of R-hydroxynitrile lyases from the Rosaceae family either a) of the amino acid residue which corresponds to position 360 of the mature PaHNL5 protein by another apolar amino acid or a neutral amino acid and/or b) of the amino acid residue which corresponds to position 225 of the mature PaHNL5 protein by another polar amino acid, it also being possible where appropriate for 1 to 20 further residues in the active center or in the hydrophobic channel leading to the active center to be replaced. | 02-18-2010 |
20150302142 | DETERMINING NOVEL ENZYMATIC FUNCTIONALITIES USING THREE-DIMENSIONAL POINT CLOUDS REPRESENTING PHYSICO CHEMICAL PROPERTIES OF PROTEIN CAVITIES - The invention relates to a method for determining catalophores including the steps of creating a point cloud database for target protein structures; creating a query point cloud; and searching said database with said query to thereby identify one or more catalophores. | 10-22-2015 |
Lukas Gruber, Graz AT
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20130271625 | PHOTOMETRIC REGISTRATION FROM ARBITRARY GEOMETRY FOR AUGMENTED REALITY - Photometric registration from an arbitrary geometry for augmented reality is performed using video frames of an environment captured by a camera. A surface reconstruction of the environment is generated. A pose is determined for the camera with respect to the environment, e.g., using model based tracking using the surface reconstruction. Illumination data for the environment is determined from a video frame. Estimated lighting conditions for the environment are generated based on the surface reconstruction and the illumination data. For example, the surface reconstruction may be used to compute the possible radiance transfer, which may be compressed, e.g., using spherical harmonic basis functions, and used in the lighting conditions estimation. A virtual object may then be rendered based on the lighting conditions. Differential rendering may be used with lighting solutions from the surface reconstruction of the environment and a second surface reconstruction of the environment combined with the virtual object. | 10-17-2013 |
20150262412 | AUGMENTED REALITY LIGHTING WITH DYNAMIC GEOMETRY - Methods for determination of AR lighting with dynamic geometry are disclosed. A camera pose for a first image comprising a plurality of pixels may be determined, where each pixel in the first image comprises a depth value and a color value. The first image may correspond to a portion of a 3D model. A second image may be obtained by projecting the portion of the 3D model into a camera field of view based on the camera pose. A composite image comprising a plurality of composite pixels may be obtained based, in part, on the first image and the second image, where each composite pixel in a subset of the plurality of composite pixels is obtained, based, in part, on a corresponding absolute difference between a depth value of a corresponding pixel in the first image and a depth value of a corresponding pixel in the second image. | 09-17-2015 |
Manuel Gruber, Steyr AT
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20110162613 | INTERNAL COMBUSTION ENGINE OIL TANK ARRANGEMENT - An internal combustion engine has a crankcase, a crankshaft, a cylinder block, and cylinder head assembly. The cylinder block has at least one cylinder. At least one piston is disposed in the at least one cylinder. The at least one piston is operatively connected to the crankshaft. An oil tank enclosure is connected to at least one of the crankcase outer wall and the cylinder block outer wall. The oil tank enclosure and the at least one of the crankcase outer wall and the cylinder block outer wall together form an oil tank. The arrangement of the oil inlet, oil outlet, and blow-by gas outlet in an oil tank; an oil tank having an angled portion for separating blow-by gases from oil; and an arrangement of a blow-by gas passage connected to an oil tank are also described. | 07-07-2011 |
Michael Gruber, Friesach AT
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20110150612 | ORDER-PICKING SYSTEM FOR ORDER-PICKING ARTICLES INTO ORDER CONTAINERS - The invention refers to an order picking plant for order picking of articles into order containers. The order picking plant comprises a picking station and a sorter. Between the sorter and order container a number of collection points are provided. Further, the invention relates to a process where the articles are stored intermediately in a collection point between sorter and order container. | 06-23-2011 |
Michael Gruber, Anger AT
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20090010741 | AUTOMATED SYSTEM AND METHOD OF AUTOMATICALLY ORDER-PICKING OR CONSOLIDATING ARTICLES - The invention relates to a method for automatically order-picking or consolidating articles of a wide variety of different formats and varieties, using the following steps: separating the stored articles, storing the articles in a rack bay, retrieving the articles and palletising them. The method is predominantly characterized in that the articles which are to be order-picked for an order are put together in a rack bay already in the sequence which is necessary for palletising. The invention also relates to an installation for implementing the method. | 01-08-2009 |
Michael Gruber, Graz AT
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20090040322 | ENHANCING DIGITAL IMAGES USING SECONDARY OPTICAL SYSTEMS - Apparatuses and methods for enhancing a “primary” large format, digital, macro-image with “secondary” image data are provided. The secondary image data is collected utilizing one or more secondary optical systems having at least one electro-optical detector array (e.g., a CCD array) and a specific set of optical mirrors or optical prisms, arranged in such a way that the secondary optical systems extend the angular angle-of-view of the primary optical system and the resultant digital image in at least two opposing directions, for instance, in the left and right and/or fore and aft directions. The primary image data and the secondary image data may be distinct and/or may include portions that overlap with one another. Further, the primary image data and the secondary image data may be collected at the same or different resolutions. The collected primary image data and secondary image data are utilized to generate a single output image. | 02-12-2009 |
20090040323 | ENHANCING DIGITAL IMAGES USING SECONDARY OPTICAL SYSTEMS - Apparatuses and methods for enhancing a “primary” large format, digital, macro-image with “secondary” image data are provided. The secondary image data is collected utilizing one or more secondary optical systems having at least one electro-optical detector array (e.g., a CCD array) and a specific set of optical mirrors or optical prisms, arranged in such a way that the secondary optical systems extend the angular field-of-view of the primary optical system and the resultant digital image in at least two opposing directions, for instance, in the left and right and/or fore and aft directions. The primary image data and the secondary image data may be distinct and/or may include portions that overlap with one another. Further, the primary image data and the secondary image data may be collected at the same or different resolutions. The collected primary image data and secondary image data are utilized to generate a single output image. | 02-12-2009 |
20090041368 | ENHANCING DIGITAL IMAGES USING SECONDARY OPTICAL SYSTEMS - Apparatuses and methods for enhancing a “primary” large format, digital, macro-image with “secondary” image data are provided. The secondary image data is collected utilizing one or more secondary optical systems having at least one electro-optical detector array (e.g., a CCD array) and a specific set of optical mirrors or optical prisms, arranged in such a way that the secondary optical systems extend the angular field-of-view of the primary optical system and the resultant digital image in at least two opposing directions, for instance, in the left and right and/or fore and aft directions. The primary image data and the secondary image data may be distinct and/or may include portions that overlap with one another. Further, the primary image data and the secondary image data may be collected at the same or different resolutions. The collected primary image data and secondary image data are utilized to generate a single output image. | 02-12-2009 |
20100182396 | DATA CAPTURE SYSTEM - A system that facilitates collecting data is described herein. The system includes a digital camera that is configured to capture images in a visible light spectrum and a near-infrared camera that is configured to capture near infrared images, wherein a field of view of the digital camera and the field of view of the near-infrared camera are substantially similar. The system further includes a trigger component that is configured to cause the digital camera and the near-infrared camera to capture images at a substantially similar point in time, and also includes a mounting mechanism that facilitates mounting the digital camera and the near-infrared camera to an automobile. | 07-22-2010 |
20110122223 | MULTI-RESOLUTION DIGITAL LARGE FORMAT CAMERA WITH MULTIPLE DETECTOR ARRAYS - A large format digital camera has a primary camera system configured for collecting panchromatic image data and two or more secondary camera systems configured for collecting color image data. Each of the secondary camera systems has an optical system that has a longer focal length than the optical system of the primary camera system. The resolution of each of the secondary camera systems is also greater than the resolution of the primary camera system. The footprint of images produced by the primary camera system is larger in size than the footprint of images produced by the secondary camera systems. Images produced by the primary camera system offer information for performing image-based georeferencing by means of photogrammetric triangulation. Images produced by the secondary camera systems offer a high-resolution narrow angle color image suitable for use in ortho image production. | 05-26-2011 |
20110122300 | LARGE FORMAT DIGITAL CAMERA WITH MULTIPLE OPTICAL SYSTEMS AND DETECTOR ARRAYS - A large format digital camera has a primary camera system configured for collecting panchromatic image data and a secondary camera system configured for collecting color image data. The secondary camera system has an optical system that has a longer focal length than the optical system of the primary camera system. The resolution of the secondary camera system is greater than the resolution of the primary camera system. The footprint of images produced by the primary camera system is larger in size than the footprint of images produced by the secondary camera system. Images produced by the primary camera system offer information for performing image-based georeferencing by means of photogrammetric triangulation. Images produced by the secondary camera system offer a high-resolution narrow angle color image suitable for use in ortho image production. | 05-26-2011 |
20140300736 | MULTI-SENSOR CAMERA RECALIBRATION - One or more techniques and/or systems are providing for facilitating recalibration of a multi-sensor camera. That is, a multi-sensor camera may comprise a nadir sensor and one or more oblique sensors. Temperature, mechanical stress, and other factors can lead to misalignment of one or more sensors within the multi-sensor camera. Accordingly, a set of tie points and/or observations may be generated based upon a search matching technique, a densification technique, and/or a virtual matching technique. A bundle technique may be utilized to generate updated eccentricity information based upon the set of tie points and/or observations. The updated eccentricity information (e.g., orientation and/or position information of a sensor, such as an oblique sensor, with respect to a nadir view) may be used to recalibrate the multi-sensor camera, such as in real-time (e.g., during a flight mission that utilizes the multi-sensor camera to capture aerial images of a city or other scene). | 10-09-2014 |
20150326783 | THREE DIMENSIONAL IMAGE CAPTURE SYSTEM FOR IMAGING BUILDING FACADES USING A DIGITAL CAMERA, A NEAR-INFRARED CAMERA, AND LASER RANGE FINDER - A system that facilitates collecting data is described herein. The system includes a digital camera that is configured to capture images in a visible light spectrum and a near-infrared camera that is configured to capture near infrared images, wherein a field of view of the digital camera and the field of view of the near-infrared camera are substantially similar. The system further includes a trigger component that is configured to cause the digital camera and the near-infrared camera to capture images at a substantially similar point in time, and also includes a mounting mechanism that facilitates mounting the digital camera and the near-infrared camera to an automobile. | 11-12-2015 |
Petra Gruber, Vienna AT
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20150093431 | COMPOSITIONS - The present invention relates to a composition comprising at least one mimotope of an epitope of alpha-synuclein for use in a method for preventing and/or treating synucleinopathies, wherein said at least one mimotope is coupled or fused to a pharmaceutically acceptable carrier protein selected from the group consisting of a non-toxic diphtheria toxin mutant, keyhole limpet hemocyanin (KLH), diphtheria toxin (DT), tetanus toxid (TT) and | 04-02-2015 |
20150306194 | METHOD FOR TREATING A SYNUCLEIOPATHY - A method for preventing and/or treating a synucleinopathy, comprising administering a composition containing at least one mimotope of an epitope of alpha-synuclein, wherein said at least one mimotope is coupled or fused to a pharmaceutically acceptable carrier protein selected from the group consisting of a non-toxic diphtheria toxin mutant, keyhole limpet hemocyanin (KLH), diphtheria toxin (DT), tetanus toxid (TT) and | 10-29-2015 |
Ronald Gruber, Steyr AT
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20150101628 | SCALP PROTECTOR - A scalp protector for the application of free-flowing hair treatment agents, in which according to the invention a comb-like first bundle of tines (1) protruding from a first web (3) having tines extending essentially parallel to one another is provided, wherein a cover element which adjustably constricts the free space between the tines is provided. The invention therefore represents a mechanical barrier, which is inserted into the hair at the point to be treated and remains there during the duration of the treatment. Since according to the invention a cover element, which adjustably constricts the free space between the teeth, is provided, the cover element can primarily be selected so that the free space is enlarged and easy insertion into the hair is possible. In the further proceedings, the cover element can be adjusted so that the free space is constricted and the scalp is completely covered down to the regions in which the individual hairs aligned in the free space between the tines pass through. Furthermore, different embodiments of the cover element are proposed. | 04-16-2015 |
Rudolf Gruber, Prambachkirchen AT
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20080265474 | Tiltable Metallurgical Vessel - A tiltable metallurgical vessel having a carrying ring at least partially around it. A metallurgical supporting bracket fastened on the metallurgical vessel rests on the ring. The vessel is releasably fixed on the support ring by a clamping device actuated by a pressure-medium cylinder. The clamping means interacts with a locking bracket fastened on the vessel. The clamping device moves between a release position, releasing it from the locking bracket and clamping position, clamping the locking bracket together with the support ring, The clamping device comprises a housing, a clamping anchor, a pivot lever and a pressure-medium cylinder, which acts on the pivot lever. The clamping anchor is guided in a pivotable manner in a guide means in the housing. The anchor is pivotably articulated on a pivotable lever, and the pivot lever is supported in a pivotable manner in the housing. | 10-30-2008 |
Sabine Gruber, Reifnitz AT
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20160139077 | Apparatus for Analyzing Ion Kinetics in Dielectrics - An apparatus for analyzing ion kinetics in a dielectric probe structure includes an ion reservoir abutting the dielectric probe structure and configured to supply mobile ions to the dielectric probe structure, a capacitor structure configured to generate an electric field in the dielectric probe structure along a vertical direction, and an electrode structure configured to generate an electrophoretic force on mobile ions in the dielectric probe structure along a lateral direction. A method for analyzing ion kinetics in the dielectric probe structure of the apparatus is also provided. | 05-19-2016 |
Stefan Gruber, Roitham AT
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20080283322 | POWER TRANSMISSION WHEEL WITH TORSIONAL DAMPERS - A power transmission wheel having a hub and a rim is disclosed. The hub has a central annular portion for operatively engaging a power transmitting shaft. The rim has an inner annular portion and an outer annular portion for operatively engaging a flexible power transmitting element. The central annular portion is disposed inside the inner annular portion with a rolling-element bearing therebetween. At least one hub blade is disposed radially between the inner and outer annular portions. At least one rim blade extends radially from one of the inner and outer annular portions towards the other of the inner and outer annular portions. The power transmission wheel has at least two elastomeric dampers. Each damper is interposed between one of the at least one hub blade and one of the at least one rim blade. An engine and vehicles using the power transmission wheels are also disclosed. | 11-20-2008 |
20110162613 | INTERNAL COMBUSTION ENGINE OIL TANK ARRANGEMENT - An internal combustion engine has a crankcase, a crankshaft, a cylinder block, and cylinder head assembly. The cylinder block has at least one cylinder. At least one piston is disposed in the at least one cylinder. The at least one piston is operatively connected to the crankshaft. An oil tank enclosure is connected to at least one of the crankcase outer wall and the cylinder block outer wall. The oil tank enclosure and the at least one of the crankcase outer wall and the cylinder block outer wall together form an oil tank. The arrangement of the oil inlet, oil outlet, and blow-by gas outlet in an oil tank; an oil tank having an angled portion for separating blow-by gases from oil; and an arrangement of a blow-by gas passage connected to an oil tank are also described. | 07-07-2011 |
Thomas Gruber, Brixen I. T. AT
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20120040864 | Method for Determining the Cbl-b Expression - The present invention relates to methods of determining intracellular Cbl-b protein in cells of a sample, comprising | 02-16-2012 |
Werner Gruber, Kindberg AT
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20100077376 | Creating an executable configuration - The automatization unit used in current test stands is a central system in which various interfaces are connected with the individual test stand components. As a result, an inflexible system is created with limited scalability, as numerous changes are required in the automatization unit, for example, a new interface, processing of data from/to the component, integration into the existing system, etc. in order to integrate new components (SW and HW). This makes a change or an enhancement of the automatization unit, the implementation of specific customer requests or the integration of an external functionality very expensive. In order to solve this problem and primarily, to make a flexible easily scalable system possible it is proposed in accordance with the invention, to create an executable configuration that can be run on a target system by selecting from a library | 03-25-2010 |
Wolfgang Gruber, Landshut AT
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20150183305 | Functionally Optimized Fiber Composite Component and Method for the Production Thereof - A fiber composite component is provided, particularly for a vehicle structure, having a fiber structure which includes at least one fiber layer, wherein at least one of the at least one fiber layers is formed from a number of pre-formed fiber mats, and a first pre-formed fiber mat has a greater fiber mat thickness than a second pre-formed fiber mat from the number of pre-formed fiber mats of the at least one fiber layer. A method for producing a corresponding fiber composite component is also provided. | 07-02-2015 |
Wolfgang Gruber, Salzburg AT
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20140371251 | METHOD OF INHIBITING DYRK1B - The present invention relates to a DYRK1B inhibitor for use in the treatment of cancer, wherein in said cancer and/or in cells of said cancer the hedgehog signaling pathway is activated, and in particular the activation of the hedgehog signaling pathway is independent of signaling by the G protein-coupled receptor Smoothened. | 12-18-2014 |