Patent application number | Description | Published |
20080233179 | TRANSDERMAL COMPOSITION HAVING ENHANCED COLOR STABILITY - A pharmaceutical composition for transdermal or transmucosal delivery of a pharmaceutical agent effective to treat a neurological disorder such as Parkinson's disease is disclosed. The composition contains an antioxidant, which provides color and chemical stability of the pharmaceutical agent. The antioxidant may also provide enhanced skin permeability of the agent. | 09-25-2008 |
20080260842 | PERMEATION ENHANCING COMPOSITIONS FOR ANTICHOLINERGIC AGENTS - A transdermal or topical skin-friendly composition including anticholinergic agents, such as oxybutynin, a urea-containing compound and a carrier system. A method is disclosed for treating a subject for urinary incontinence while reducing the incidences of peak concentrations of drug and undesirable side effects associated with oral anticholinergics. | 10-23-2008 |
20090069364 | PHARMACEUTICAL COMPOSITIONS OF 5-ALPHA-REDUCTASE INHIBITORS AND METHODS OF USE THEREOF - Non-occlusive compositions for transdermal delivery of 5-alpha-reductase inhibitors, and more particularly finasteride or dutasteride or pharmaceutically acceptable salts or derivatives thereof, and methods of making same. The composition may, for example, be a gel suitable for transdermal or transmucosal applications. The compositions of the present invention typically include a mixture of water and alcohol, and a solvent system having a mono alkyl ether of diethylene glycol and a glycol present in specified ratios and in specific amounts, wherein the pH of the gel is usually between about pH 4.5 and about pH 8. The compositions may include further components, for example, the hydroalcoholic vehicle may further include additional penetration enhancer(s), buffering agent(s), antioxidant(s), stabilizer(s) and/or gelling agent(s). Also, a method for the sustained delivery of 5-alpha-reductase inhibitors to treat a variety of conditions and disorders. | 03-12-2009 |
20100216880 | TRANSDERMAL COMPOSITIONS FOR ANTICHOLINERGIC AGENTS - The present invention relates generally to compositions or formulations for transdermal or transmucosal administration of anticholinergic agents such as oxybutynin. The invention utilizes a novel delivery vehicle and is a substantially malodorous-free and irritation free transdermal formulation which is substantially free of long chain fatty alcohols, long-chain fatty acids, and long-chain fatty esters. A method is disclosed for treating a subject for urinary incontinence with these formulations while reducing the incidences of peak concentrations of drug and undesirable side effects associated with oral anticholinergics. | 08-26-2010 |
20110195114 | TRANSDERMAL DELIVERY SYSTEMS FOR ACTIVE AGENTS - A delivery vehicle for topical pharmaceutical formulations that include a C2 to C4 alkanol, a polyalcohol, and a monoalkyl ether of diethylene glycol present in relative amounts sufficient to provide permeation enhancement of an active agent through mammalian dermal or mucosal surfaces. Preferably, the delivery vehicle as well as the formulations that contain it are substantially free of long-chain fatty alcohols, long-chain fatty acids and long-chain fatty esters in order to avoid potential undesirable odor and irritation effects caused by such compounds during use of the formulation. Without these additives, use of the formulations is facilitated and patient compliance is greater | 08-11-2011 |
20110245215 | TRANSDERMAL DELIVERY SYSTEMS FOR ACTIVE AGENTS - A formulation for transdermal or transmucosal administration of an active agent. The formulation includes an active agent and a delivery vehicle comprising a C | 10-06-2011 |
20110257141 | TRANSDERMAL PHARMACEUTICAL FORMULATION FOR MINIMIZING SKIN RESIDUES - This invention relates to novel transdermal or transmucosal pharmaceutical formulation having an active agent of testosterone which reduces the occurrences of contamination of other individuals and the transference to clothing of the user. The solvent system of the formulation includes a monoalkylether of diethylene glycol and a glycol present in specified ratios, and a mixture of water and alcohol. The invention also relates to a method for inhibiting or delaying crystallization of the active agent in a pharmaceutical formulation. | 10-20-2011 |
20120294934 | TRANSDERMAL COMPOSITIONS FOR ANTICHOLINERGIC AGENTS - The present invention relates generally to compositions or formulations for transdermal or transmucosal administration of anti-cholinergic agents such as oxybutynin. The invention utilizes a novel delivery vehicle and is a substantially malodorous-free and irritation free transdermal formulation which is substantially free of long chain fatty alcohols, long-chain fatty acids, and long-chain fatty esters. A method is disclosed for administering such formulations to a person in need thereof while reducing the incidences of peak concentrations of drug and undesirable side effects associated with oral anti-cholinergics. | 11-22-2012 |
20130045953 | NESTORONE.RTM./ESTRADIOL TRANSDERMAL GEL - The invention discloses compositions and methods for ensuring in both women of fertile age where it ensures also a contraception with additional health benefits and in postmenopausal women where it offers a hormonal therapy with additional medical benefits such as the potential for lower risk of thrombosis. The aforementioned compositions comprising NES as a potent progestational and antiovulatory agent with no androgenic nor estrogenic nor glucocorticoid effect, and combined with estradiol formulated for non-oral transdermal administration as specific daily doses. | 02-21-2013 |
20130295166 | TESTOSTERONE FORMULATIONS - The subject invention provides improved testosterone gel formulations. | 11-07-2013 |
20150110856 | TESTOSTERONE FORMULATIONS - The subject invention provides improved testosterone gel formulations. | 04-23-2015 |
20150297507 | DICLOFENAC FORMULATIONS - The subject invention provides improved diclofenac gel formulations. | 10-22-2015 |
Patent application number | Description | Published |
20100307412 | HOT-DIP GALVANIZING INSTALLATION FOR STEEL STRIP - An installation for the hardened galvanization of a continuously-moving rolled steel strip, includes a coating tank receiving a liquid metal mixture containing, for example, zinc and aluminum to be deposited on the strip which is immersed in the mixture. The liquid mixture is permanently circulated between the coating tank and a preparation device, in which the temperature of the liquid mixture is deliberately lowered in order to reduce an iron solubility threshold and is sufficiently high for initiating fusion of at least one ingot containing a zinc-aluminum Zn—Al alloy in a so-called fusion zone of the preparation device, in an amount necessary to compensate for the liquid mixture used for deposition on the strip. The installation includes a loop for circulating the liquid mixture that is thermally optimized. | 12-09-2010 |
20100323095 | METHOD FOR THE HARDENED GALVANIZATION OF A STEEL STRIP - A method produces a hardened galvanization of a continuously-running rolled steel strip. The strip is immersed in a coating tank containing a bath of a liquid metal mixture, e.g. zinc and aluminum, to be deposited on the strip, and permanently circulated between the coating tank and a preparation device. The temperature of the liquid mixture is deliberately lowered in order to reduce the iron solubility threshold and sufficiently high for initiating, in the preparation device, the fusion of at least one Zn—Al ingot in an amount necessary for compensating for the liquid mixture used for deposition on the strip. The device is implemented so that the circuit for circulating the liquid mixture is thermally optimized. | 12-23-2010 |
20110177258 | METHOD AND DEVICE FOR WIPING LIQUID COATING METAL AT THE OUTLET OF A TEMPERING METAL COATING TANK - A method and device disclose how to drain a liquid coating metal from the two sides of a running steel strip. The method transfers a strip coated with a liquid coating metal, as it runs at the tank outlet, from a region not subjected to a magnetic field to another region subjected to a static magnetic field generated between the poles of magnetic members arranged opposite each other on either side of the strip and having field lines, or at least a main shell of the field lines, intersecting with the strip over at least one minimum longitudinal extent so that the liquid coating metal is correlatively subjected to a magnetic field variation generating on the liquid metal a force opposite to the running direction. Due to the low field variation, this magnetic braking effect generates little Foucault current in the strip. | 07-21-2011 |
20110222057 | METHOD AND DEVICE FOR MEASURING A CHEMICAL COMPOSITION OF A LIQUID METAL SUITABLE FOR COATING A STEEL STRIP - A method and a device measure a chemical composition of a liquid metal suitable for coating a steel strip. The method measures a chemical composition of a liquid metal suitable for coating a steel strip for which the liquid metal is formed continuously in a first cavity, and the composition of the liquid metal is measured on a direct measurement surface thereof, for which a specimen of the liquid metal reaching the measurement surface is heated to a chosen temperature so as to isolate principally iron-based impurities from the measurement surface. Several embodiments of devices suitable for implementing the method are also presented. | 09-15-2011 |
20110265604 | METHOD AND DEVICE FOR CONTROLLING THE INTRODUCTION OF SEVERAL METALS INTO A CAVITY DESIGNED TO MELT SAID METALS - A method and a device control the introduction of several metals into a cavity configured to melt the metals in the form of ingots. In particular, the method is configured to control the introduction of several metals into a cavity for melting the metals so as to dip-coat a steel strip with the metals in liquid metal form. Whereby a first metal is introduced in the form of at least a first ingot having a high content of the first metal and a second metal is introduced in the form of at least a second ingot formed as an alloy of the first metal and the second metal. The second metal content of the second ingot is chosen from a range of significant contents for ensuring an intended overall flow rate for combined melting of the ingots, the range of significant contents being chosen in a limited interval of sequentially increasing values so as to minimize differences between melting points of the ingots. | 11-03-2011 |