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Patent application number | Description | Published |
20090114808 | Mass spectrometer - A method of mass spectrometry is disclosed wherein voltage signals from an ion detector are analysed. A second differential of each voltage signal is obtained and the start and end times of observed voltage peaks are determined. The intensity and average time of each voltage peak is then determined and the intensity and time values are stored. An intermediate composite mass spectrum is then formed by combining the intensity and time values which relate to each voltage peak observed from multiple experimental runs. The various pairs of time and intensity data are then integrated to produce a smooth continuum mass spectrum. The continuum mass spectrum may then be further processed by determining the second differential of the continuum mass spectrum. The start and end times of mass peaks observed in the continuum mass spectrum may be determined. The intensity and mass to charge ratio of each mass peak observed in the continuum mass spectrum may then determined. A final discrete mass spectrum comprising just of an intensity value and mass to charge ratio per species of ion may then be displayed or output. | 05-07-2009 |
20100237237 | TANDEM ION TRAPPING ARRANGEMENT - A mass spectrometer is disclosed comprising a first storage ion trap ( | 09-23-2010 |
20100301206 | Mass Spectrometer - An ion-ion reaction cell is provided comprising a plurality of electrodes ( | 12-02-2010 |
20110024618 | Mass Spectrometer - An ion-ion reaction cell is provided comprising a plurality of electrodes (1) forming an ion guide (2). A transient DC voltage wave is applied to the electrodes (2) in order to load reagent anions into the ion guide (2). Analyte cations are then subsequently transmitted through the ion-ion reaction cell by a subsequent transient DC voltage wave. Ion are arranged to undergo ion-ion reactions within the reaction cell and the resulting fragment ions which are formed within the reaction cell are then subsequently translated out of the reaction cell by means of a transient DC voltage wave. | 02-03-2011 |
20110049358 | Linear Ion Trap - A linear ion trap ( | 03-03-2011 |
20110062323 | Electron Transfer Dissociation Device - A mass spectrometer is disclosed comprising an Electron Transfer Dissociation device comprising an ion guide. A control system determines the degree of fragmentation and charge reduction of precursor ions within the ion guide and varies the speed at which ions are transmitted through the ion guide in order to optimise the fragmentation and charge reduction process. | 03-17-2011 |
20110189788 | Glow Discharge Ion Source - A mass spectrometer is disclosed comprising a glow discharge device within the initial vacuum chamber of the mass spectrometer. The glow discharge device may comprise a tubular electrode ( | 08-04-2011 |
20110303838 | Method Of Avoiding Space Charge Saturation Effects In An Ion Trap - A mass spectrometer is provided comprising a first ion trap ( | 12-15-2011 |
20120119078 | Ion Population Control Device For A Mass Spectrometer - A mass spectrometer is disclosed wherein an ion beam attenuator is arranged upstream of an ion trap mass analyser. An ion tunnel ion trap comprising an upstream ion accumulation section and a downstream ion accumulation section is arranged upstream of the ion beam attenuator. Ions are released from the ion tunnel ion trap and the intensity of the ion beam which is transmitted to the ion trap analyser is controlled by the ion beam attenuator. The fill time during which ions are admitted into the ion trap mass analyser remains substantially constant and is substantially independent of the intensity of the ion beam. | 05-17-2012 |
20120126110 | Method of Processing Mass Spectral Data - A method of processing mass spectral data is disclosed comprising digitizing a first signal output from an ion detector to produce a first digitised signal. A first set of peaks in the first digitised signal is detected and the arrival time T | 05-24-2012 |
20130112865 | Method of Avoiding Space Charge Saturation Effects In An Ion Trap - A mass spectrometer includes a first ion trap arranged upstream of an analytical second ion trap. The charge capacity of the first ion trap is set at a value such that if all the ions stored within the first ion trap up to the charge capacity limit of the first ion trap are then transferred to the second ion trap, then the analytical performance of the second ion trap is not substantially degraded due to space charge effects. | 05-09-2013 |
20130119247 | Mass Spectrometer - A mass spectrometer is disclosed wherein an ion signal is split into a first and second signal. The first and second signals are multiplied by different gains and are digitised. Arrival time and intensity pairs are calculated for both digitised signals and the resulting time and intensity pairs are combined to form a high dynamic range spectrum. The spectrum is then combined with other corresponding spectra to form a summed spectrum. | 05-16-2013 |
20140166877 | Method of Processing Mass Spectral Data - A method of processing mass spectral data is disclosed comprising digitising a first signal output from an ion detector to produce a first digitised signal. A first set of peaks in the first digitised signal is detected and the arrival time T | 06-19-2014 |
20140284471 | Mass Spectrometers Comprising Accelerator Devices - A method of mass spectrometry is disclosed comprising providing a flight region for ions to travel through and a detector or fragmentation device. A potential profile is maintained along the flight region such that ions travel towards the detector or fragmentation device. The potential at which a first length of the flight region is maintained is then changed from a first potential to a second potential whilst at least some ions are travelling within the first length of flight region. The changed potential provides a first potential difference at an exit of the length of flight region, through which the ions are accelerated as they leave the length of flight region. This increases the kinetic energy of the ions prior to them reaching the detector or fragmentation cell. | 09-25-2014 |
20140291507 | Multi Inlet For Solvent Assisted Inlet Ionisation - A mass spectrometer is disclosed comprising a dual channel Solvent Assisted Inlet Ionisation (“SAII”) interface. | 10-02-2014 |
20140326867 | Mass Spectrometer - A mass spectrometer is disclosed wherein an ion signal is split into a first and second signal. The first and second signals are multiplied by different gains and are digitised. Arrival time and intensity pairs are calculated for both digitised signals and the resulting time and intensity pairs are combined to form a high dynamic range spectrum. The spectrum is then combined with other corresponding spectra to form a summed spectrum. | 11-06-2014 |
20140367564 | Method of Avoiding Space Charge Saturation Effects in an Ion Trap - A mass spectrometer is provided comprising a first ion trap arranged upstream of an analytical second ion trap. The charge capacity of the first ion trap is set at a value such that if all the ions stored within the first ion trap up to the charge capacity limit of the first ion trap are then transferred to the second ion trap, then the analytical performance of the second ion trap is not substantially degraded due to space charge effects. | 12-18-2014 |