Patent application number | Description | Published |
20100229303 | Modular user-assembled adjustable, and high-low adjustable, beds - In an adjustable bed having juxtaposed between a mattress and a floor an articulated frame, and one or more wired motors operating on the articulated frame so that the mattress resting atop the frame is adjusted in contour, the articulated frame is modular, and ships in two or more modular frame sections each of which is sufficiently small so as to fit upon a standard shipping pallet of 48″ by 48″. Moreover, and further, the two or more modular frame sections semi-permanently engage by sliding protrusions—preferably a steel tubes—extending from spaced-parallel frame rails of a one section into a complimentary cavities of the frame rails—preferably steel tubes of square cross section—of a next frame section. This sliding assembly may be done by one adult man, without use of tools. The extensive contact between the telescoping members makes that the connection, and the modular adjustable bed itself, is suitably strong. | 09-16-2010 |
20100229309 | Mattress retainer - A mattress retainer for use with an adjustable bed having a rectilinear foot-region frame section with a planar upper surface substantially operates to “clip” this frame section, extending upwards at the foot of the adjustable bed to retain the mattress. Preferably made from a contiguous piece of bent metal, the mattress retainer (1) ships inverted in position on the foot-region frame section of a modular adjustable bed, and (2) is erected to operational position upon the bed by one person without use of tools. | 09-16-2010 |
20150040313 | MODULAR USER-ASSEMBLED ADJUSTABLE, AND HIGH-LOW ADJUSTABLE BEDS - A frame for an adjustable has a head section with two longitudinal frame rails separated by at least two lateral members extending between the two longitudinal frame rails, and two sleeves each having a cavity with one of the two sleeves on each of the two longitudinal frame rails. The frame has a foot section having two longitudinal frame rails separated by at least two lateral members extending between the two longitudinal frame rails, and two sleeves each having a cavity with one of the two sleeves on each of the two longitudinal frame rails, and an inner tube with a nose for each of the two sleeves and for moving between a first position retracted in the cavity of the sleeve and a second position extending from the cavity of the sleeve. | 02-12-2015 |
Patent application number | Description | Published |
20110157431 | Method and System for Directing Cameras - A system and a method for directing a camera based on time-series data are disclosed, wherein the time-series data represent atomic activities sensed by sensors in an environment, and wherein each atomic activity includes a time and a location at which the each atomic activity is sensed, comprising: providing a spatio-temporal pattern of the specified atomic activity, wherein the spatio-temporal pattern is based only on the time and the location of the atomic activities, such that a spatio-temporal sequence of the atomic activities forms the specified primitive activity; detecting, in the time-series data, a sensed primitive activity corresponding to the spatio-temporal pattern to produce a result, wherein the detecting is performed by a processor; and directing the camera based on the result. | 06-30-2011 |
20110187502 | Active Badge Localization Using Passive Sensors - A network in an environment includes passive sensors with associated sensor identification numbers. A set of active badges with associated badge identification numbers, wherein each badge is associated with an object, and wherein a particular sensor broadcasts a packet in response to detecting a particular object, wherein the packet includes the sensor identification number and a time, and only if the particular object is associated with a particular badge then the badge appends the badge identification number to the packet and broadcasts the appended packet, and the particular sensor receives and rebroadcasts the appended packet for further processing to passively and actively monitor the environment. | 08-04-2011 |
20130119027 | Laser Cutting Machine - A laser cutting machine includes a platform and a motion system. The motion system includes a first prismatic joint facilitating a first motion of the platform along a first direction and a second prismatic joint facilitating a second motion of the platform along a second direction. A galvano arranged on the platform, such that a motion of the platform causes a motion of the galvano, the galvano including a first mirror, wherein a third motion of the first mirror positions the laser beam along a third direction, and a second minor, wherein a fourth motion of the second mirror positions the laser beam along a fourth direction. A control module controls concurrently the motion system and the galvano, such that a position of the laser beam on the workpiece is a vector sum of the first motion, the second motion, the third motion, and the fourth motion. | 05-16-2013 |
Patent application number | Description | Published |
20130036237 | CONTINUOUS DEPLOYMENT OF APPLICATIONS - Concepts and technologies are described herein for continuously deploying applications. In accordance with the concepts and technologies disclosed herein, a first host environment executes an application. An upgrade for the application is released by creating a backup of the application and content used by the application and restoring the backup at a second host environment. The application hosted by the second host environment is upgraded, traffic is routed to the second host environment, and performance of the upgraded application is monitored. If errors are detected in the upgraded application, the upgrade can be rolled back, and traffic can be rerouted back to the first host environment. If the errors are not detected, traffic can be increasingly routed to the second host environment and the first host environment can be deactivated. | 02-07-2013 |
20130036328 | MANAGING CONTINUOUS SOFTWARE DEPLOYMENT - Concepts and technologies are described herein for managing continuous software deployment. A deployment controller can manage deployment of code to a data center. The deployment controller can execute workflows for checking in, verifying, deploying the code, or other processes. The code can be deployed using a differencing disk that includes data indicating changes between software hosted by the data center and a version of software resulting from deployment of the code. The differencing disk can be linked to the disk or virtual resource hosting the software and executed collectively to provide an updated version of the software. Traffic to one or more virtual machines of the data center can be controlled by the deployment controller. If errors are detecting during deployment or after updating, the update can be rolled back. | 02-07-2013 |
20130036402 | USING VIRTUAL MACHINES TO MANAGE SOFTWARE BUILDS - Concepts and technologies are described herein for using virtual machines to manage software builds. A deployment controller manages deployment of a new software build. The deployment controller installs the new software build on test device and tests the new software build. If the new software build functions without errors, the new software build is deployed to hosts of a data center and monitored for errors. If errors are detected, the errors are reported to a developer associated with the new software build. In some embodiments, the deployment controller creates a differencing disk storing differences between the updated software build and an existing software build and uses the differencing disk for installing the new software build for testing and/or for deploying the new software build. | 02-07-2013 |
Patent application number | Description | Published |
20140187213 | GLOBAL CONTACT SYNCHRONIZATION - A situational and global context aware calendar, communications, and/or relationship management method and system is disclosed. The system is configured to receive non-calendaring related context information, and, based on that context information, to automatically determine one or more parameters of a meeting request. | 07-03-2014 |
20140188541 | SITUATIONAL AND GLOBAL CONTEXT AWARE CALENDAR, COMMUNICATIONS, AND RELATIONSHIP MANAGEMENT - A situational and global context aware calendar, communications, and/or relationship management method and system is disclosed. The system is configured to receive non-calendaring related context information, and, based on that context information, to automatically determine one or more parameters of a meeting request. | 07-03-2014 |
20140188776 | DECISION MAKING USING ALGORITHMIC OR PROGRAMMATIC ANALYSIS - A system for determining an instruction in a first time limit that can be executed by an executing system is disclosed. The system is configured to request proposed action regarding an event from each of a plurality of operator systems. In some embodiments, the system can calculate a score for each of the proposed actions received from the plurality of operator systems. The system can then automatically determine an instruction in a first time limit based on the calculated scored and command the executing system to execute the instruction. | 07-03-2014 |
20150154327 | DECISION MAKING USING ALGORITHMIC OR PROGRAMMATIC ANALYSIS - A system for determining an instruction in a first time limit that can be executed by an executing system is disclosed. The system is configured to request proposed action regarding an event from each of a plurality of operator systems. In some embodiments, the system can calculate a score for each of the proposed actions received from the plurality of operator systems. The system can then automatically determine an instruction in a first time limit based on the calculated scored and command the executing system to execute the instruction. | 06-04-2015 |
20150156606 | GLOBAL CONTACT SYNCHRONIZATION - A situational and global context aware calendar, communications, and/or relationship management method and system is disclosed. The system is configured to receive non-calendaring related context information, and, based on that context information, to automatically determine one or more parameters of a meeting request. | 06-04-2015 |
20150173969 | EXTRA-PROTECTION PADS AND RELATED METHODS - Extra-protection fins and pads, and methods of making and using extra-protection fins and pads are disclosed. The extra-protection fins and pads of the present invention comprise a first triangular face, a second triangular face attached and/or connected to the first triangular face at an angle thereby forming a front apex and a top apex, wherein the fins are configured such that the front apex catches and/or absorbs the menstrual and/or other vaginal fluids first, and the extra-protection fin fills backwards toward the top apex, thus preventing unwanted, embarrassing and annoying leakage onto clothing or bedding during periods of heavy flow and/or when lying down. The extra-protection fin may also comprise a third triangular face attached and/or connected to the first and second triangular faces, wherein a vertex of the third triangular face contacts and/or is connected to the first and second triangular faces at the top apex. | 06-25-2015 |
Patent application number | Description | Published |
20100286791 | Integrated system for the ballistic and nonballistic infixion and retrieval of implants - Provided are methods and apparatus for the use of magnetic traction to maintain the patency of a tubular anatomical structure, whether a vessel, duct, the trachea, bronchus, bile duct, ureter, vas deferens, fallopian tube, or portions of the digestive tract, as to constitute means for extraluminal stenting. An extraluminal stent consists of a perimedial or medial intravascular and an extravascular component. The intravascular component consists of ferromagnetic spherules implanted aeroballistically or stays implanted by means of a special hand tool, while the extravascular component consists of a pliant jacket or mantle that has magnets mounted about its outer surface. A catheter adapted for use as the barrel of a gas-operated implant insertion gun is so devised that it can be used independently to perform an angioplasty and thereafter have its free or extracorporeal end inserted into the airgun to initiate implantation of the intravascular component without the need for withdrawal and reinsertion through the introducer sheath. When the implants must be spaced too closely together to be controlled by hand, a positional control system is used to effect discharge automatically. Spherules that consist entirely of medication or that have a radiation emitting seed as the core can be implanted with the same apparatus. A glossary of terms follows the specification. | 11-11-2010 |
20140163664 | Integrated system for the ballistic and nonballistic infixion and retrieval of implants with or without drug targeting - Described are coordinated apparatus and methods for drug targeting, clearing the lumen, placing implants within the wall of, and stenting, as necessary, any tubular anatomical structure with single luminal entry. Miniature balls, or miniballs, are introduced into the wall aeroballistically from within the lumen, or small arcuate bands called stays inserted through the outer tunic by means of a hand tool. When miniballs must be placed too closely together to be controlled by hand, a positional control system assists in discharge. Implantation within or proximal to diseased tissue targeting, and thus concentrating the medication in that tissue, miniballs and stays can be used to deliver and controllably release multiple drugs, a radionuclide, or an open or closed loop smart-pill, for example. A glossary of terms follows the specification. Balance of abstract appended to paragraph [ | 06-12-2014 |
Patent application number | Description | Published |
20080217820 | Tissue scaffold having aligned fibrils, apparatus and method for producing the same, and artificial tissue and methods of use thereof - A tubular tissue scaffold is described which comprises a tube having a wall, wherein the wall includes biopolymer fibrils that are aligned in a helical pattern around the longitudinal axis of the tube where the pitch of the helical pattern changes with the radial position in the tube wall. The scaffold is capable of directing the morphological pattern of attached and growing cells to form a helical pattern around the tube walls. Additionally, an apparatus for producing such a tubular tissue scaffold is disclosed, the apparatus comprising a biopolymer gel dispersion feed pump that is operably connected to a tube-forming device having an exit port, where the tube-forming device is capable of producing a tube from the gel dispersion while providing an angular shear force across the wall of the tube, and a liquid bath located to receive the tubular tissue scaffold from the tube-forming device. A method for producing the tubular tissue scaffolds is also disclosed. Also, artificial tissue comprising living cells attached to a tubular tissue scaffold as described herein is disclosed. Methods for using the artificial tissue are also disclosed. | 09-11-2008 |
20080220506 | Tissue scaffold having aligned fibrils, apparatus and method for producing the same, and artificial tissue and methods of use thereof - A tubular tissue scaffold is described which comprises a tube having a wall, wherein the wall includes biopolymer fibrils that are aligned in a helical pattern around the longitudinal axis of the tube where the pitch of the helical pattern changes with the radial position in the tube wall. The scaffold is capable of directing the morphological pattern of attached and growing cells to form a helical pattern around the tube walls. Additionally, an apparatus for producing such a tubular tissue scaffold is disclosed, the apparatus comprising a biopolymer gel dispersion feed pump that is operably connected to a tube-forming device having an exit port, where the tube-forming device is capable of producing a tube from the gel dispersion while providing an angular shear force across the wall of the tube, and a liquid bath located to receive the tubular tissue scaffold from the tube-forming device. A method for producing the tubular tissue scaffolds is also disclosed. Also, artificial tissue comprising living cells attached to a tubular tissue scaffold as described herein is disclosed. Methods for using the artificial tissue are also disclosed. | 09-11-2008 |
Patent application number | Description | Published |
20090289125 | Thermanator Radiator - A heating system for heating an interior room may include a radiator member for generating heat, a wall member being positioned in a space relationship to the radiator member; and a panel member being positioned between the radiator member and the wall member. The panel member may include an inclined surface, and the panel member may include a horizontal surface. The inclined surface may extend to an edge of the horizontal surface, and the panel member may include a substantially flat back surface. The panel member may be attached to the wall member by a first attachment device, and the panel member may be attached to the radiator member by a second attachment device. The second attachment device may be a hook device, and the second attachment device may detachably connect the radiator member to the panel member. | 11-26-2009 |
20090308942 | Thermanator Thermal Insulation Retrofit Panel - A heating system for heating an interior room may include a radiator member for generating heat, a wall member being positioned in a space relationship to the radiator member and a panel member being positioned between the radiator member and the wall member. The panel member may include an attachment member to attach the panel member to the wall member, and the panel member may include an inclined surface. The panel member may include a horizontal surface, and the panel member may include an inclined surface and a horizontal surface. The inclined surface may extend to an edge of the horizontal surface, and the panel member may include a substantially flat back surface. The attachment member may be a layer of adhesive, and the attachment member may substantially cover a back surface of the panel member. The attachment member may only cover a portion of the back surface of the panel member. The panel member may encapsulate air for insulation. | 12-17-2009 |
20100237056 | Thermal Insulation Energy Saver Device - A heating system for heating an interior room may include a radiator member for generating heat, a wall member being positioned in a space relationship to the radiator member and a device member being positioned between the radiator member and the wall member. The device member will have two inner radiant barriers of silver aluminized material protected by paint or lamination. The device member may include an attachment member to attach the device member to the wall member, and the device member may include an inclined surface. The device member may include a horizontal surface, and the device member may include an inclined surface and a horizontal surface. The inclined surface may extend to an edge of the horizontal surface, and the device member may include a substantially flat back surface. The attachment member may be a layer of adhesive, and the attachment member may cover the perimeter of the back surface of the device member. The attachment member may only cover a portion of the back surface of the panel member. The device member may encapsulate air for insulation. | 09-23-2010 |
Patent application number | Description | Published |
20100318590 | FILE SYSTEM LOCATION VERIFICATION USING A SENTINEL - A new file system is mounted to a mount point of an existing file system implemented in a computational system. A sentinel indicator is stored in the mount point. Prior to initiating an input/output (I/O) operation by a program, a determination is made by the program as to whether the sentinel indicator exists. In response to determining by the program that the sentinel indicator exists, the I/O operation is performed by the program. In certain alternative embodiments, in response to determining by the program that the sentinel indicator exists, the I/O operation is not performed by the program. | 12-16-2010 |
20120317157 | FILE SYSTEM LOCATION VERIFICATION USING A SENTINEL - A new file system is mounted to a mount point of an existing file system implemented in a computational system. A sentinel indicator is stored in the mount point. Prior to initiating an input/output (I/O) operation by a program, a determination is made by the program as to whether the sentinel indicator exists. In response to determining by the program that the sentinel indicator exists, the I/O operation is performed by the program. In certain alternative embodiments, in response to determining by the program that the sentinel indicator exists, the I/O operation is not performed by the program. | 12-13-2012 |
20120317158 | FILE SYSTEM LOCATION VERIFICATION USING A SENTINEL - A new file system is mounted to a mount point of an existing file system implemented in a computational system. A sentinel indicator is stored in the mount point. Prior to initiating an input/output (I/O) operation by a program, a determination is made by the program as to whether the sentinel indicator exists. In response to determining by the program that the sentinel indicator exists, the I/O operation is performed by the program. In certain alternative embodiments, in response to determining by the program that the sentinel indicator exists, the I/O operation is not performed by the program. | 12-13-2012 |
20120323980 | FILE SYSTEM LOCATION VERIFICATION USING A SENTINEL - A new file system is mounted to a mount point of an existing file system implemented in a computational system. A sentinel indicator is stored in the mount point. Prior to initiating an input/output (I/O) operation by a program, a determination is made by the program as to whether the sentinel indicator exists. In response to determining by the program that the sentinel indicator exists, the I/O operation is performed by the program. In certain alternative embodiments, in response to determining by the program that the sentinel indicator exists, the I/O operation is not performed by the program. | 12-20-2012 |
Patent application number | Description | Published |
20140006746 | VIRTUAL MEMORY ADDRESS RANGE REGISTER | 01-02-2014 |
20140157410 | Secure Environment for Graphics Processing Units - In accordance with some embodiments, a protected execution environment may be defined for a graphics processing unit. This framework not only protects the workloads from malware running on the graphics processing unit but also protects those workloads from malware running on the central processing unit. In addition, the trust framework may facilitate proof of secure execution by measuring the code and data structures used to execute the workload. If a part of the trusted computing base of this framework or protected execution environment is compromised, that part can be patched remotely and the patching can be proven remotely throughout attestation in some embodiments. | 06-05-2014 |
20150033012 | SECURE PROCESSING ENVIRONMENT MEASUREMENT AND ATTESTATION - Embodiments of an invention for secure processing environment measurement and attestation are disclosed. In one embodiment, a processor includes an instruction unit and an execution unit. The instruction unit is to receive a first instruction associated with a build or a rebuild of a secure enclave. The execution unit is to execute the first instruction. Execution of the first instruction, when associated with the build, includes calculation of a first measurement and a second measurement of the secure enclave. Execution of the first instruction, when associated with the rebuild, includes calculation of the second measurement without calculation of the first measurement. | 01-29-2015 |
20150033316 | FEATURE LICENSING IN A SECURE PROCESSING ENVIRONMENT - Embodiments of an invention for feature licensing in a secure processing environment are disclosed. In one embodiment, a processor includes an instruction unit and an execution unit. The instruction unit is to receive an instruction to initialize a secure enclave. The execution unit is to execute the instruction. Execution of the instruction includes determining whether a requested feature is licensed for use in the secure enclave. | 01-29-2015 |
Patent application number | Description | Published |
20130159726 | METHOD AND APPARATUS TO PROVIDE SECURE APPLICATION EXECUTION - A technique to enable secure application and data integrity within a computer system. In one embodiment, one or more secure enclaves are established in which an application and data may be stored and executed. | 06-20-2013 |
20130198853 | METHOD AND APPARATUS TO PROVIDE SECURE APPLICATION EXECUTION - A technique to enable secure application and data integrity within a computer system. In one embodiment, one or more secure enclaves are established in which an application and data may be stored and executed. | 08-01-2013 |
20140013422 | Continuous Multi-factor Authentication - A method and computing device for continuous multi-factor authentication are included in which a plurality of valid authentication credentials may be detected. Also, an authorized user may be detected within a viewing area. Additionally, an unauthorized object may be detected in the viewing area. Furthermore, a display device may be prevented from displaying content. | 01-09-2014 |
20140096068 | DEVICE AND METHOD FOR SECURE USER INTERFACE GESTURE PROCESSING USING PROCESSOR GRAPHICS - A device and method for securely rendering content on a gesture-enabled computing device includes initializing a secure execution environment on a processor graphics of the computing device. The computing device transfers view rendering code and associated state data to the secure execution environment. An initial view of the content is rendered by executing the view rendering code in the secure execution environment. A gesture is recognized, and an updated view of the content is rendered in the secure execution environment in response to the gesture. The gesture may include a touch gesture recognized on a touch screen, or a physical gesture of the user recognized by a camera. After the updated view of the content is rendered, the main processor of the computing device may receive updated view data from the secure execution environment. | 04-03-2014 |
20140189242 | LOGGING IN SECURE ENCLAVES - Embodiments of an invention for logging in secure enclaves are disclosed. In one embodiment, a processor includes an instruction unit and an execution unit. The instruction unit is to receive an instruction having an associated enclave page cache address. The execution unit is to execute the instruction without causing a virtual machine exit, wherein execution of the instruction includes logging the instruction and the associated enclave page cache address. | 07-03-2014 |
20140189246 | MEASURING APPLICATIONS LOADED IN SECURE ENCLAVES AT RUNTIME - Embodiments of an invention for measuring applications loaded in secure enclaves at runtime are disclosed. In one embodiment, a processor includes an instruction unit and an execution unit. The instruction unit is to receive an instruction to extend a first measurement of a secure enclave with a second measurement. The execution unit is to execute the instruction after initialization of the secure enclave. | 07-03-2014 |
20140189274 | APPARATUS AND METHOD FOR PAGE WALK EXTENSION FOR ENHANCED SECURITY CHECKS - An apparatus and method for managing a protection table by a processor. For example, a processor according to one embodiment of the invention comprises: protection table management logic to manage a protection table, the protection table having an entry for each protected page or each group of protected pages in memory; wherein the protection table management logic prevents direct access to the protection table by user application program code and operating system program code but permits direct access by the processor. | 07-03-2014 |
20140189325 | PAGING IN SECURE ENCLAVES - Embodiments of an invention for paging in secure enclaves are disclosed. In one embodiment, a processor includes an instruction unit and an execution unit. The instruction unit is to receive a first instruction. The execution unit is to execute the first instruction, wherein execution of the first instruction includes evicting a first page from an enclave page cache. | 07-03-2014 |
20140189326 | MEMORY MANAGEMENT IN SECURE ENCLAVES - Embodiments of an invention for memory management in secure enclaves are disclosed. In one embodiment, a processor includes an instruction unit and an execution unit. The instruction unit is to receive a first instruction and a second instruction. The execution unit is to execute the first instruction, wherein execution of the first instruction includes allocating a page in an enclave page cache to a secure enclave. The execution unit is also to execute the second instruction, wherein execution of the second instruction includes confirming the allocation of the page. | 07-03-2014 |
20140267332 | Secure Rendering of Display Surfaces - A protected graphics module can send its output to a display engine securely. Secure communications with the display can provide a level of confidentiality of content generated by protected graphics modules against software and hardware attacks. | 09-18-2014 |
20140297962 | INSTRUCTIONS AND LOGIC TO PROVIDE ADVANCED PAGING CAPABILITIES FOR SECURE ENCLAVE PAGE CACHES - Instructions and logic provide advanced paging capabilities for secure enclave page caches. Embodiments include multiple hardware threads or processing cores, a cache to store secure data for a shared page address allocated to a secure enclave accessible by the hardware threads. A decode stage decodes a first instruction specifying said shared page address as an operand, and execution units mark an entry corresponding to an enclave page cache mapping for the shared page address to block creation of a new translation for either of said first or second hardware threads to access the shared page. A second instruction is decoded for execution, the second instruction specifying said secure enclave as an operand, and execution units record hardware threads currently accessing secure data in the enclave page cache corresponding to the secure enclave, and decrement the recorded number of hardware threads when any of the hardware threads exits the secure enclave. | 10-02-2014 |
20150089173 | SECURE MEMORY REPARTITIONING - Secure memory repartitioning technologies are described. A processor includes a processor core and a memory controller coupled between the processor core and main memory. The main memory includes a memory range including a section of convertible pages are convertible to secure pages or non-secure pages. The processor core, in response to a page conversion instruction, is to determine from the instruction a convertible page in the memory range to be converted and convert the convertible page to be at least one of a secure page or a non-secure page. The memory range may also include a hardware reserved section are convertible in response to a section conversion instruction. | 03-26-2015 |
Patent application number | Description | Published |
20090136524 | COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF TUMORS - Based on the observation of the cooperation of osteopontin (OPN) and matrixmetalloproteinase-9 (MMP-9) in the promotion of the metastatic phenotype, therapies and diagnostic assays are disclosed for the treatment of a tumor that overexpresses OPN, such as hepatocellular carcinoma (HCC), for example metastatic HCC. In one example, methods of treating a tumor include administration of an agent that reduces cellular invasion resulting from the interaction between a fragment of OPN (OPN-5kD) generated by MMP-9 cleavage and CD44 receptor. Examples of such agents include fragments of OPN-5 kD and antibodies specific for OPN-5kD. Therapeutic compositions are also provided that include such agents. Also provided are methods of diagnosing or prognosing a tumor, for example by detecting expression of OPN-5kD peptide or OPN-c mRNA in a biological sample obtained from the subject. Also provided are antibodies that specifically bind OPN-5kD. | 05-28-2009 |
20100322950 | COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF TUMORS - Based on the observation of the cooperation of osteopontin (OPN) and matrixmetalloproteinase-9 (MMP-9) in the promotion of the metastatic phenotype, therapies and diagnostic assays are disclosed for the treatment of a tumor that overexpresses OPN, such as hepatocellular carcinoma (HCC), for example metastatic HCC. In one example, methods of treating a tumor include administration of an agent that reduces cellular invasion resulting from the interaction between a fragment of OPN (OPN-5 kD) generated by MMP-9 cleavage and CD44 receptor. Examples of such agents include fragments of OPN-5 kD and antibodies specific for OPN-5 kD. Therapeutic compositions are also provided that include such agents. Also provided are methods of diagnosing or prognosing a tumor, for example by detecting expression of OPN-5 kD peptide or OPN-c mRNA in a biological sample obtained from the subject. Also provided are antibodies that specifically bind OPN-5 kD. | 12-23-2010 |
20120294870 | COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF TUMORS - Based on the observation of the cooperation of osteopontin (OPN) and matrixmetalloproteinase-9 (MMP-9) in the promotion of the metastatic phenotype, therapies and diagnostic assays are disclosed for the treatment of a tumor that overexpresses OPN, such as hepatocellular carcinoma (HCC), for example metastatic HCC. In one example, methods of treating a tumor include administration of an agent that reduces cellular invasion resulting from the interaction between a fragment of OPN (OPN-5kD) generated by MMP-9 cleavage and CD44 receptor. Examples of such agents include fragments of OPN-5kD and antibodies specific for OPN-5kD. Therapeutic compositions are also provided that include such agents. Also provided are methods of diagnosing or prognosing a tumor, for example by detecting expression of OPN-5kD peptide or OPN-c mRNA in a biological sample obtained from the subject. Also provided are antibodies that specifically bind OPN-5kD. | 11-22-2012 |
Patent application number | Description | Published |
20100159805 | RIGID OR FLEXIBLE, MACRO-POROUS ABRASIVE ARTICLE - A macro-porous abrasive article includes a spun lace substrate having a macro-porous structure and a coating. The coating is made of a resin binder and abrasive aggregates. The abrasive aggregates are formed from a composition of abrasive grit particles and a nanoparticle binder. The coating is at least partially embedded in the substrate. A method for making the macro-porous abrasive article includes combining abrasive aggregates of abrasive grit particles and a nanoparticle binder with a resin binder to form a slurry. The slurry is applied to a macro-porous support structure so that the slurry at least partially penetrates the substrate. The resin is then cured to bond the aggregate grains to the substrate. | 06-24-2010 |
20120055096 | NON-ABRASIVE BACK COAT FOR COATED ABRASIVES - An abrasive article includes a backing including first and second major surfaces, an abrasive layer disposed over the first major surface, and a back coat layer disposed over the second major surface. The back coat layer includes a polymeric material and a fabric. | 03-08-2012 |
20120192500 | COATED ABRASIVE AGGREGATES AND PRODUCTS CONTAING SAME - A coated abrasive product includes a particulate material containing green, unfired abrasive aggregates having a generally spheroidal or toroidal shape, the aggregates formed from a composition comprising abrasive grit particles, a nanoparticle binder, a dual function material, and a cross-linking agent. These green unfired abrasive aggregates can also be used in free abrasive products and bonded abrasive products. | 08-02-2012 |
Patent application number | Description | Published |
20090164470 | System for Providing Session-Based Network Privacy, Private, Persistent Storage, and Discretionary Access Control for Sharing Private Data - The invention provides secure and private communication over a network, as well as persistent private storage and private access control to the stored information, which is accomplished by imposing mechanisms that separate a user's actions from their identity. The system provides (i) anonymous network browsing, in which event the anonymity system is unaware of both the user's identity and browsing activities, (ii) private network storage and retrieval of data such as passwords, profiles and files in a manner such that the data can be stored into the system and later retrieved without the system knowing the contents or owners of the data, and (iii) the ability of the user to control and manage access to the remotely stored data without the system knowing the contents, owners, or accessors of the data. | 06-25-2009 |
20140032901 | SYSTEM FOR PROVIDING SESSION-BASED NETWORK PRIVACY, PRIVATE, PERSISTENT STORAGE, AND DISCRETIONARY ACCESS CONTROL FOR SHARING PRIVATE DATA - The invention provides secure and private communication over a network, as well as persistent private storage and private access control to the stored information, which is accomplished by imposing mechanisms that separate a user's actions from their identity. The system provides (i) anonymous network browsing, in which event the anonymity system is unaware of both the user's identity and browsing activities, (ii) private network storage and retrieval of data such as passwords, profiles and files in a manner such that the data can be stored into the system and later retrieved without the system knowing the contents or owners of the data, and (iii) the ability of the user to control and manage access to the remotely stored data without the system knowing the contents, owners, or accessors of the data. | 01-30-2014 |
20140337624 | SYSTEM FOR PROVIDING SESSION-BASED NETWORK PRIVACY, PRIVATE, PERSISTENT STORAGE, AND DISCRETIONARY ACCESS CONTROL FOR SHARING PRIVATE DATA - The invention provides secure and private communication over a network, as well as persistent private storage and private access control to the stored information, which is accomplished by imposing mechanisms that separate a user's actions from their identity. The system provides (i) anonymous network browsing, in which event the anonymity system is unaware of both the user's identity and browsing activities, (ii) private network storage and retrieval of data such as passwords, profiles and files in a manner such that the data can be stored into the system and later retrieved without the system knowing the contents or owners of the data, and (iii) the ability of the user to control and manage access to the remotely stored data without the system knowing the contents, owners, or accessors of the data. | 11-13-2014 |
Patent application number | Description | Published |
20120143385 | COMPUTING ARCHITECTURE FOR AUTONOMOUS MICROGRIDS - A computing architecture that facilitates autonomously controlling operations of a microgrid is described herein. A microgrid network includes numerous computing devices that execute intelligent agents, each of which is assigned to a particular entity (load, source, storage device, or switch) in the microgrid. The intelligent agents can execute in accordance with predefined protocols to collectively perform computations that facilitate uninterrupted control of the microgrid. | 06-07-2012 |
20120232709 | Customized Electric Power Storage Device for Inclusion in a Collective Microgrid - An electric power storage device is described herein, wherein the electric power storage device is included in a microgrid. The electric power storage device has at least one of a charge rate, a discharge rate, or a power retention capacity that has been customized for a collective microgrid. The collective microgrid includes at least two connected microgrids. The at least one of the charge rate, the discharge rate, or the power retention capacity of the electric power storage device is computed based at least in part upon specified power source parameters in the at least two connected microgrids and specified load parameters in the at least two connected microgrids. | 09-13-2012 |
20120283887 | CUSTOMIZED ELECTRIC POWER STORAGE DEVICE FOR INCLUSION IN A MICROGRID - An electric power storage device included in a microgrid is described herein. The electric power storage device has at least one of a charge rate, a discharge rate, or a power retention capacity that has been customized for the microgrid. The at least one of the charge rate, the discharge rate, or the power retention capacity of the electric power storage device is computed based at least in part upon specified power source parameters in the microgrid and specified load parameters in the microgrid. | 11-08-2012 |