Patent application number | Description | Published |
20080199534 | Stability in vitamin and mineral supplements - The invention provides a multivitamin and mineral nutritional supplement composition comprising at least one polyvalent metal and at least one oxidizable vitamin with substantially improved resistance to reactions that lead to darkening and/or spotting and reactions that may reduce the potency of oxidizable vitamins. The composition is a multivitamin and mineral composition comprising at least one polyvalent metal and at least one oxidizable vitamin wherein the composition is substantially free of mobile bound water. The invention also includes methods for making such a composition and methods of preventing or reducing oxidation, improving the stability of oxidizable vitamins, and stabilizing the disintegration time of a multi-vitamin and mineral nutritional supplement composition. | 08-21-2008 |
20080254119 | Imbedded liquid lubricants for tableting - The invention provides a nutritional supplement and/or pharmaceutical composition for tableting comprising an embedded lubrication matrix. The embedded lubrication matrix comprises an oily liquid finely dispersed in an oil insoluble material. A method of lubricating a nutritional supplement or pharmaceutical composition for tableting using a matrix with embedded lubrication is also provided. | 10-16-2008 |
20140220151 | Stability in Vitamin and Mineral Supplements - The invention provides a multivitamin and mineral nutritional supplement composition comprising at least one polyvalent metal and at least one oxidizable vitamin with substantially improved resistance to reactions that lead to darkening and/or spotting and reactions that may reduce the potency of oxidizable vitamins. The composition is a multivitamin and mineral composition comprising at least one polyvalent metal and at least one oxidizable vitamin wherein the composition is substantially free of mobile bound water. The invention also includes methods for making such a composition and methods of preventing or reducing oxidation, improving the stability of oxidizable vitamins, and stabilizing the disintegration time of a multi-vitamin and mineral nutritional supplement composition. | 08-07-2014 |
20140342047 | Embedded Liquid Lubricants for Tableting - The invention provides a nutritional supplement and/or pharmaceutical composition for tableting comprising an embedded lubrication matrix. The embedded lubrication matrix comprises an oily liquid finely dispersed in an oil insoluble material. A method of lubricating a nutritional supplement or pharmaceutical composition for tableting using a matrix with embedded lubrication is also provided. | 11-20-2014 |
Patent application number | Description | Published |
20080207085 | Novelty Figurine And Carabiner Storage Assembly - A novelty figurine and carabiner storage assembly is provided. The figurine comprises a head portion, a body portion located proximate to the head portion, and at least one carabiner attachment assembly extending from the body portion for selectively allowing the figurine to be attached to or removed from another item able to receive the attachment assembly. The carabiner attachment assembly comprises at least first and second leg assemblies, with one of the leg assemblies having a selectively openable gate assembly extending therealong. The body portion has at least one substantially hollow interior section and at least one selectively openable door assembly for access into the substantially hollow interior section. | 08-28-2008 |
20080209699 | FLUID FILLED ATTACHMENT DEVICE - An attachment device is provided comprising at least one fluid filled cavity formed therein. The attachment device is preferably in the form of a carabiner in which at least a portion of the carabiner body is formed of a transparent material such that the fluid filled cavity is visible. In a preferred embodiment an indicia bearing means is visibly disposed within said cavity. | 09-04-2008 |
20080209700 | FLUID FILLED ATTACHMENT DEVICE - An attachment device is provided comprising at least one fluid filled cavity formed therein. The attachment device is preferably in the form of a carabiner in which at least a portion of the carabiner body is formed of a transparent material such that the fluid filled cavity is visible. In a preferred embodiment an indicia bearing means is visibly disposed within said cavity. | 09-04-2008 |
20080209701 | FLUID FILLED ATTACHMENT DEVICE - An attachment device is provided comprising at least one fluid filled cavity formed therein. The attachment device is preferably in the form of a carabiner in which at least a portion of the carabiner body is formed of a transparent material such that the fluid filled cavity is visible. In a preferred embodiment an indicia bearing means is visibly disposed within said cavity. | 09-04-2008 |
Patent application number | Description | Published |
20120331174 | SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT FOR RESOLVING ADDRESSING IN A NETWORK INCLUDING A NETWORK ADDRESS TRANSLATOR - A system, method, and computer program product through which address resolution is performed for nodes of a network that are behind a network address translator (NAT). A determination is made upon the initiation of a communication session as to whether one or more of the nodes included in the session are behind a NAT. Based on the determination, information is exchanged from an independent application server to the nodes included in the session so as to resolve the addressing problems introduced by the NAT. The invention is applicable in applications including, but not limited to, IP telephony, and applications complying with the session initiation protocol (SIP). | 12-27-2012 |
20160080434 | System, Method, and Computer Program Product For Resolving Addressing In A Network Including A Network Address Translator - A system, method, and computer program product through which address resolution is performed for nodes of a network that are behind a network address translator (NAT). A determination is made upon the initiation of a communication session as to whether one or more of the nodes included in the session are behind a NAT. Based on the determination, information is exchanged from an independent application server to the nodes included in the session so as to resolve the addressing problems introduced by the NAT. The invention is applicable in applications including, but not limited to, IP telephony, and applications complying with the session initiation protocol (SIP). | 03-17-2016 |
Patent application number | Description | Published |
20090062450 | Barrier coating a non-elastomeric polymer and a dispersed layered filler in a liquid carrier and coated articles - Barrier coating mixtures contain in a carrier liquid, (a) a non-elastomeric polymer; (b) an exfoliated layered platelet-like silicate filler which may or may not have been acid or base treated that has not been functionalized with organic cations having an aspect ratio greater than 25; and (c) at least one additive, wherein the total solids content is less than 30% and the amount of filler is between 5% to about 60% of the total solids content. Coated articles and containers, freestanding films and packaging films are produced using the barrier coating mixtures. Methods of manufacturing such coated products are also encompassed. | 03-05-2009 |
20090285722 | Collection container assembly with nanocomposite barrier coating - An evacuated container assembly suitable for use in connection with blood collection including: (a) a container member formed of a first polymeric material and having a sidewall and one or more openings; (b) a nanocomposite barrier coating disposed on the container member having a thickness of up to about 30 microns and being derived from an aqueous dispersion including (i) a dispersed barrier matrix polymer; and (ii) a substantially exfoliated silicate filler having an aspect ratio of more than 50; and (c) one or more sealing members disposed in the opening(s) operative to hermetically seal the cavity; wherein the cavity is evacuated and maintains a pressure below atmospheric pressure and exhibits a draw volume loss lower than that of a like assembly without a nanocomposite barrier film by a factor of at least 1.5. | 11-19-2009 |
20110054105 | BARRIER COATING COMPOSITES WITH HYPERPLATY CLAY AND POLYESTER MATRIX RESIN - An aqueous barrier coating composition in the form of a dispersion includes: (a) water; (b) a polyester matrix polymer; (c) a platy to hyperplaty kaolin filler having an average shape factor of at least about 40:1, the composition being further characterized in that: (i) the composition has a solids content of from more than 20 weight percent up to 70 percent by weight; (ii) the composition has a weight ratio of polyester matrix polymer:kaolin filler of from 4:1 to 0.75:1; and (iii) a film formed from the composition exhibits at least 5-fold reduction in oxygen permeability as compared with a like film formed of said polyester matrix polymer. Also disclosed are barrier coatings derived from the compositions as well as packaging composites incorporating a barrier film formed from the compositions. | 03-03-2011 |
20120046405 | BARRIER COATINGS STABILIZED WITH MULTI-VALENT METAL CATIONS - A method of making a composite barrier coating composition comprising: (a) providing a first aqueous dispersion comprising a dispersed, anionically functionalized matrix resin; (b) providing a second aqueous dispersion comprising a dispersed platy mineral filler; the first and second dispersions optionally including one or more additives selected from the group consisting surfactants, emulsifiers, anti-foaming agents, dispersing agents, wetting agents, leveling agents and thickeners; (c) adding a multi-valent metal cation crosslinking agent to at least one of said first and second aqueous dispersions; and (d) admixing the first and second aqueous dispersions to form the composite wherein the composite forms a stable aqueous emulsion and the multi-valent metal cation is operative to stabilize a film formed from the composite against gas barrier performance loss at elevated levels of relative humidity. | 02-23-2012 |
20120208034 | FILMS AND ARTICLES HAVING A BARRIER COATING DERIVED FROM CONCENTRATED AQUEOUS NANOCOMPOSITE DISPERSIONS - Films or other articles having a barrier coating derived from a concentrated nanocomposite dispersion which includes a silicate filler and a matrix polymer dispersed in an aqueous medium. The dispersions are condensed by selectively removing liquid therefrom to provide high solids coating formulations. | 08-16-2012 |
Patent application number | Description | Published |
20120190668 | ENHANCEMENT OF CELLULAR TRANSPLANTATION USING SMALL MOLEUCLE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY - The present invention provides methods for enhancing cellular transplantation by exposing cells in vitro or ex vivo, or a recipient of cells, to a small molecule hepatocyte growth factor/scatter factor mimetic. Exemplary compounds are described. | 07-26-2012 |
20130190376 | METHODS OF USE OF SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY - The present invention provides methods for treating a disease or condition by administering to a subject at a frequency of more than 24 hours between doses, compositions and formulations of compounds having formula (I), and pharmaceutically acceptable derivatives thereof, wherein p, R1, R2 and B are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of injuries, conditions or diseases in which HGF/SF or the activities thereof, or agonists or antagonists thereof have a therapeutically useful role. | 07-25-2013 |
20140171419 | ENHANCEMENT OF CELLULAR TRANSPLANTATION USING SMALL MOLECULE MODULATORS HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY - The present invention provides methods for enhancing cellular transplantation by exposing cells in vitro or ex vivo, or a recipient of cells, to a small molecule hepatocyte growth factor/scatter factor mimetic. Exemplary compounds are described. | 06-19-2014 |
20150105380 | METHODS AND USES OF COMPOUNDS FOR TREATING DISEASE - The present invention provides methods for treating polycystic kidney disease by administering a compound or pharmaceutical composition thereof having the general structural formula (I) | 04-16-2015 |
20160038490 | COMPOSITIONS AND METHODS FOR TREATING DYSPROLIFERATIVE DISEASES - Methods are provided for treating cancer and other dysproliferative diseases by administering to a subject in need there of a therapeutically effective amount of a synergistic composition comprising an HER2 inhibitor, or a pharmaceutically acceptable salt or prodrug thereof; and a CYP26 inhibitor, or a pharmaceutically acceptable salt or prodrug thereof; wherein said therapeutically effective amount suppresses the growth of dysproliferative cells in vivo. Compositions comprising a combination of an HER2 inhibitor, or a pharmaceutically acceptable salt or prodrug thereof; and a CYP26 inhibitor a pharmaceutically acceptable salt or prodrug thereof are also described. | 02-11-2016 |
20160060322 | RELAXIN-LIKE PEPTIDES AND USES THEREOF - The present invention is directed to novel peptides that exhibit relaxin activity, and uses thereof for treating diseases such as heart failure and liver, lung, cardiac or kidney fibrosis. | 03-03-2016 |
Patent application number | Description | Published |
20080269134 | DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES FOR DELIVERING ACTIVE AGENTS - The inventors have discovered that the disodium salt of certain delivery agents has surprisingly greater efficacy for delivering active agents than the corresponding monosodium salt. Furthermore, the inventors have discovered that the disodium salts of these delivery agents form solvates with ethanol and hydrates with water. The delivery agents have the formula | 10-30-2008 |
20090264368 | COMPOSITIONS FOR DELIVERING PARATHYROID HORMONE AND CALCITONIN - The present invention relates to a composition comprising a delivery agent, parathyroid hormone, and calcitonin. This composition exhibits increased delivery of parathyroid hormone and/or calcitonin and is useful for the treatment of osteoporosis. The composition also permits simultaneous oral delivery of parathyroid hormone and calcitonin. The composition of the present invention may be formulated into a dosage unit form, such as an oral dosage unit form. The invention also provides a method for administering parathyroid hormone and calcitonin to an animal in need thereof by administering the composition of the present invention. | 10-22-2009 |
20100099621 | DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES FOR DELIVERING ACTIVE AGENTS - The inventors have discovered that the disodium salt of certain delivery agents has surprisingly greater efficacy for delivering active agents than the corresponding monosodium salt. Furthermore, the inventors have discovered that the disodium salts of these delivery agents form solvates with ethanol and hydrates with water. The delivery agents have the formula | 04-22-2010 |
20110251125 | DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES FOR DELIVERING ACTIVE AGENTS - The inventors have discovered that the disodium salt of certain delivery agents has surprisingly greater efficacy for delivering active agents than the corresponding monosodium salt. Furthermore, the inventors have discovered that the disodium salts of these delivery agents form solvates with ethanol and hydrates with water. The delivery agents have the formula | 10-13-2011 |
20120264834 | DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES FOR DELIVERING ACTIVE AGENTS - The inventors have discovered that the disodium salt of certain delivery agents has surprisingly greater efficacy for delivering active agents than the corresponding monosodium salt. Furthermore, the inventors have discovered that the disodium salts of these delivery agents form solvates with ethanol and hydrates with water. Preferred delivery agents include, but are not limited to, N-(5-chlorosalicyloyl)-8-aminocaprylic acid (5-CNAC), N-(10-[2-hydroxybenzoyl]amino)decanoic acid (SNAD), and sodium N-(8-[2-hydroxybenzoyl]amino)caprylate (SNAC). The invention also provides methods of preparing the disodium salt, ethanol solvate, and hydrate and compositions containing the disodium salt, ethanol solvate, and/or hydrate. | 10-18-2012 |
Patent application number | Description | Published |
20090144781 | AUDIO-ON-DEMAND COMMUNICATION SYSTEM - An audio-on-demand communication system provides real-time playback of audio data transferred via telephone lines or other communication links. One or more audio servers include memory banks which store compressed audio data. At the request of a user at a subscriber PC, an audio server transmits the compressed audio data over the communication link to the subscriber PC. The subscriber PC receives and decompresses the transmitted audio data in less than real-time using only the processing power of the CPU within the subscriber PC. According to one aspect of the present invention, high quality audio data compressed according to lossless compression techniques is transmitted together with normal quality audio data. According to another aspect of the present invention, metadata, or extra data, such as text, captions, still images, etc., is transmitted with audio data and is simultaneously displayed with corresponding audio data. The audio-on-demand system also provides a table of contents indicating significant divisions in the audio clip to be played and allows the user immediate access to audio data at the listed divisions. According to a further aspect of the present invention, servers and subscriber PCs are dynamically allocated based upon geographic location to provide the highest possible quality in the communication link. | 06-04-2009 |
20120148064 | AUDIO ON-DEMAND COMMUNICATION SYSTEM - An audio-on-demand communication system provides real-time playback of audio data transferred via telephone lines or other communication links. One or more audio servers include memory banks which store compressed audio data. At the request of a user at a subscriber PC, an audio server transmits the compressed audio data over the communication link to the subscriber PC. The subscriber PC receives and decompresses the transmitted audio data in less than real-time using only the processing power of the CPU within the subscriber PC. According to one aspect of the present invention, high quality audio data compressed according to lossless compression techniques is transmitted together with normal quality audio data. According to another aspect of the present invention, metadata, or extra data, such as text, captions, still images, etc., is transmitted with audio data and is simultaneously displayed with corresponding audio data. | 06-14-2012 |