Patent application number | Description | Published |
20090196826 | COMPOSITIONS AND METHODS OF MAKING NON-SPHERICAL MICRO- AND NANO-PARTICLES - The present invention includes compositions, methods and pharmaceutical compositions formed by template-directed polymer molding by contacting a porous template with one or more layers of polymeric material coated on a release layer coated on a substrate, applying pressure to the porous template, the substrates or both and separating the porous template from the polymer material to form one or more polymer nonspherical nanostructures with one or more layers on the substrate. The template includes one or more nonspherical nanostructure features. The size and shape of the one or more single- or multi-layer polymeric nonspherical nanostructures are controlled by the one or more nonspherical nanostructure features and the polymer material optionally including one or more active agents with or without retardants, dyes, etc. | 08-06-2009 |
20090266418 | PHOTOVOLTAIC DEVICES BASED ON NANOSTRUCTURED POLYMER FILMS MOLDED FROM POROUS TEMPLATE - The present invention includes a template, an optoelectronic device and methods for making the same. The optoelectronic device includes a first substrate; a first electrode disposed on the first substrate; a first interdigitating, nano-structured charge-transfer molded material (e.g., a polymer) with a first electron affinity disposed on the first electrode; a second interdigitating, nano-structured charge-transfer material (e.g., single molecules, quantum dots, or particles) with a second electron affinity disposed on the first interdigitating, nano-structured charge-transfer material; a second electrode disposed in the second interdigitating, nano-structured charge-transfer material; and a second substrate disposed on the second electrode. | 10-29-2009 |
20130331426 | pH-SENSITIVE COMPOSITIONS FOR DELIVERY OF BETA LAPACHONE AND METHODS OF USE - Disclosed herein are compounds comprising a polymer conjugated with a pH-sensitive prodrug of beta-lapachone, wherein the compound is capable of forming a micelle, and wherein the pH-sensitive prodrug comprises a pH-sensitive linker selected from the group consisting of: an aryl imine and an aliphatic imine. Also provided are micelles comprised of such polymer-prodrug conjugates. Further provided are methods for treating cancer with the micelles. | 12-12-2013 |
20140023590 | NOVEL BLOCK COPOLYMER AND MICELLE COMPOSITIONS AND METHODS OF USE THEREOF - Provided herein are block copolymers comprising a hydrophilic polymer segment and a hydrophobic polymer segment, wherein the hydrophilic polymer segment comprises a polymer selected from the group consisting of: poly(ethylene oxide) (PEO), poly(methacrylate phosphatidyl choline) (MPC), and polyvinylpyrrolidone (PVP), wherein the hydrophobic polymer segment comprises wherein R′ is —H or —CH | 01-23-2014 |
Patent application number | Description | Published |
20080294270 | DIFFERENTIALLY PROCESSED TISSUE AND PROCESSING METHODS THEREOF - A method of preparing an implantable biological device having a first tissue part and a second tissue part includes exposing the first tissue part to a first preparation method and preventing exposure of the second biological tissue part to the first preparation method. Preventing exposure of the second biological tissue part to the first preparation method may be achieved using an embedding technique, a coating technique, a covering technique, or physical isolation. The method may further include exposing the second tissue part to a second preparation method and preventing exposure of the first biological tissue part to the second preparation method. An apparatus for preparing an implantable biologic device includes an enclosure having first and second chambers separated by a partition member wherein a substantial portion of the first tissue part is within the first chamber and a substantial portion of the second tissue part is within the second chamber. | 11-27-2008 |
20090012629 | COMPOSITIONS AND METHODS FOR TISSUE REPAIR - Implants for repairing tissue defects, such as cartilage tissue defects, and methods of their preparation and use are disclosed. A mold of a tissue defect is prepared by pressing upon the defect a substrate having shape memory, such as aluminum foil. The mold, which has contours substantially conforming to those of the defect, is removed from the defect, and tissue particles are added to the mold ex vivo. A biological carrier such as biocompatible glue is also added to the mold. The combination of tissue particles and the biological carrier thereby form an implant, which retains its shape after separation from the mold. The implant can be transferred to the tissue defect, with contours of the mold matching corresponding contours of the defect. | 01-08-2009 |
20090202642 | Drug Delivery System Comprising Microparticles and Gelation System - Disclosed are drug delivery compositions comprising a continuous aqueous phase comprising a reverse thermal gelation system comprising a blend of a cellulose derivative and polyethylene glycol; a discontinuous particulate phase comprising microparticles; and an agent to be delivered contained in at least said discontinuous particulate phase. Also disclosed are sustained release compositions formed using the drug delivery compositions and methods of using those compositions. | 08-13-2009 |
20100191281 | Apparatus and Method for Delivering a Biocompatible Material to a Surgical Site - A device for delivering a biocompatible material to a surgical site includes a cannula having proximal and distal portions and at least a first interior lumen disposed therebetween through which the biocompatible material is delivered. The device further includes an initiation member for initiating cross-linking of the biocompatible material while the biocompatible material is within the cannula. The cannula may include a heating element to thermally initiate cross-linking. Alternately, the cannula may include a second lumen for transmitting light from a light source. A movable blocking element controls the amount of light that passes into the first lumen. A method of delivering a curable biocompatible material to a surgical site includes positioning a distal portion of a cannula adjacent the surgical site and introducing the biocompatible material through a first lumen of the cannula. Cross-linking of the biocompatible material is then initiated while the biocompatible material is within the cannula. | 07-29-2010 |
20100297766 | Method of Removing Undesired Tissue from Connective Tissue - A method of removing undesired tissue from a connective tissue is provided that includes stretching the connective tissue and peeling away the undesired tissue. Some methods include soaking the connective tissue in a solution prior to and/or subsequent to stretching and peeling away the undesired tissue. The solution may include a detergent, an enzyme, a salt solution, an organic solvent, and combinations thereof. | 11-25-2010 |
20120003176 | HYDROGEL-FORMING COMPOSITION COMPRISING NATURAL AND SYNTHETIC SEGMENTS - A hydrogel composition is formed from a natural polymer derivative having a plurality of cross-linkable units depending therefrom, and a synthetic polymer derivative having a plurality of cross-linkable units depending therefrom, said natural and synthetic polymer derivatives having hydrolysable units disposed between the polymer backbone of said derivative and at least some of said cross-linkable units. The use of a combination of natural and synthetic polymers provides for biodegradability of the hydrogel, along with mechanical properties such as strength and elasticity. | 01-05-2012 |
20120003192 | HYDROGEL-FORMING COMPOSITION COMPRISING PROTEIN AND NON-PROTEIN SEGMENTS - A hydrogel-forming composition is formed from a protein polymer derivative having a plurality of cross-linkable units depending therefrom, and a non-protein polymer derivative having a plurality of cross-linkable units depending therefrom, said non-protein polymer derivatives having hydrolysable units disposed between the polymer backbone of said derivative and at least some of said cross-linkable units. The use of a combination of protein and non-protein polymers provides for biodegradability of the hydrogel by hydrolysis of the hydrolysable units and/or enzymatic degradation of the proteins, along with mechanical properties such as strength and elasticity. | 01-05-2012 |
20120020932 | THERMOSENSITIVE HYDROGEL COMPOSITION AND METHOD - A hydrogel-forming composition is provided that comprises an extracellular matrix protein, hyaluronic acid, and a thermosensitive biocompatible polymer such as methylcellulose. The hydrogels can provide a therapeutic effect; further, the hydrogels may comprise an optional therapeutic agent such as cells or a pharmaceutical composition. The composition may be injected to an area in need of treatment by the therapeutic agent. The composition may form a gel at about 37° C., such that the gel maintains the therapeutic agent in the area of the body in need of such treatment. | 01-26-2012 |
20120107384 | APPARATUS FOR FORMING AN IMPLANT - Implants for repairing tissue defects, such as cartilage tissue defects, and methods of their preparation and use are disclosed. A mold of a tissue defect is prepared by pressing upon the defect a substrate having shape memory, such as aluminum foil. The mold, which has contours substantially conforming to those of the defect, is removed from the defect, and tissue particles are added to the mold ex vivo. A biological carrier such as biocompatible glue is also added to the mold. The combination of tissue particles and the biological carrier thereby form an implant, which retains its shape after separation from the mold. The implant can be transferred to the tissue defect, with contours of the mold matching corresponding contours of the defect. | 05-03-2012 |
20140107593 | FENESTRATED NEEDLE FOR DELIVERING THERAPEUTIC REAGENTS INTO SOFT TISSUE - An embodiment of the claimed invention is a therapeutic delivery device having a plurality of fenestrations located around the circumference of its distal portion and an opening at the tip. The opening at the tip and the plurality of fenestrations reduce the injection resistance, making it easy to use, and ensure an even distribution of the injected material at the recipient location. | 04-17-2014 |
20140114285 | BONE MARROW ASPIRATION DEVICE - An embodiment of the invention is directed to a bone marrow aspiration device comprising a plurality of syringes, each of which operates in a series of sequential steps to obtain bone marrow of high quality and therapeutic value, i.e., having a high MSC/ml number. An embodiment of the invention preferably comprises three syringes, wherein a first syringe is used to aspirate bone marrow from a subject, a second syringe contains an anticoagulant, and the third syringe contains a mixture of the bone marrow aspirate and the anticoagulant. | 04-24-2014 |
Patent application number | Description | Published |
20100174105 | Production of Substituted Phenylene Aromatic Diesters - The present disclosure is directed to the production of 5-tert-butyl-3-methyl-1,2-phenylene dibenzoate and the purification thereof. Synthesis pathways for a precursor to 5-tert-butyl-3-methyl-1,2-phenylene dibenzoate are provided. The precursor is 5-tert-butyl-3-methylcatechol. | 07-08-2010 |
20100204506 | Production of Substituted Phenylene Aromatic Diesters and Compositions - The present disclosure provides processes for the production of substituted phenylene aromatic diesters and the resultant compositions. The processes include reacting an aromatic diol with an aromatic carboxylic acid or a derivative thereof. The aromatic diol and/or the aromatic carboxylic acid (or derivative thereof) is/are substituted. The reaction forms a substituted phenylene aromatic diester with the structure (II): | 08-12-2010 |
20100273966 | Procatalyst Composition with Adamantane and Method - Disclosed are procatalyst compositions having an internal electron donor which includes an adamantanedicarboxylate and optionally an electron donor component. Ziegler-Natta catalyst compositions containing the present procatalyst compositions produce propylene-based olefins with broad molecular weight distribution. | 10-28-2010 |
20110130529 | THREE AND FOUR ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE - A solid, hydrocarbon-insoluble, catalyst component useful in polymerizing olefins, said catalyst component containing magnesium, titanium, and halogen, and further containing an internal electron donor having a structure: | 06-02-2011 |
20110130530 | TWO ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE - A solid, hydrocarbon-insoluble, catalyst component useful in polymerizing olefins, said catalyst component containing magnesium, titanium, and halogen, and further containing an internal electron donor having a structure: | 06-02-2011 |
20120316299 | Amide Ester Internal Electron Donor and Process - Disclosed is a process for producing a procatalyst composition having an amide ester internal electron donor. The process includes pre-halogenating a procatalyst precursor before reaction with the amide ester and forming the procatalyst composition. Ziegler-Natta catalyst compositions containing the present procatalyst composition exhibit improved catalyst activity and/or improved catalyst selectivity and produce propylene-based olefins with broad molecular weight distribution. | 12-13-2012 |
20120322964 | Halogenated Amide Ester and Internal Electron Donor with Same - Disclosed are halogenated amide esters that are suitable as internal electron donors in procatalyst compositions. Ziegler-Natta catalyst compositions containing the present procatalyst compositions exhibit improved catalyst activity and/or improved catalyst selectivity and produce propylene-based olefins with broad molecular weight distribution. | 12-20-2012 |
20130245306 | TWO ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE - A compound suitable for use as an internal electron donor having a structure: | 09-19-2013 |
20130261273 | Process for Production of High Melt Flow Propylene-Based Polymer and Product from Same - Disclosed are catalyst compositions having an internal electron donor which includes a 3,6-di-substituted-1,2-phenylene aromatic diester. Ziegler-Natta catalyst compositions containing the present catalyst compositions exhibit very high hydrogen response, high activity, high selectivity and produce propylene-based olefins with high melt flow rate. | 10-03-2013 |
20140012035 | Production of Substituted Phenylene Aromatic Diesters - Synthesis pathways for a precursor to 5-tert-butyl-3-methyl-1, 2-phenylene dibenzoate are provided. The precursor is methylcatechol and/or 5-tert-butyl-3-methylcatechol. | 01-09-2014 |
20140163184 | Procatalyst Composition with Substituted Amide Ester Internal Electron Donor - Disclosed are procatalyst compositions having an internal electron donor which includes a substituted amide ester and optionally an electron donor component. Ziegler-Natta catalyst compositions containing the present procatalyst compositions exhibit improved catalyst activity and/or improved catalyst selectivity and produce propylene-based olefins with broad molecular weight distribution. | 06-12-2014 |
Patent application number | Description | Published |
20110031972 | METHOD AND SYSTEM OF DETERMINING AN ELECTRICAL PROPERTY OF A FORMATION FLUID - Determining an electrical property of a formation fluid. At least some of the illustrative embodiments are methods comprising drawing formation fluids into a tool within a borehole, applying a swept frequency electric field to the formation fluids by way of a first winding, inducing a current flow in a second winding based on the swept frequency electric field, and determining a property of the formation fluids based, at least in part, on the current flow in the second winding. | 02-10-2011 |
20110164468 | METHOD AND SYSTEM OF TRANSMITTING ACOUSTIC SIGNALS FROM A WELLBORE - Transmitting acoustic signals from a wellbore. At least some of the illustrative embodiments are methods including transmitting an acoustic signal comprising downhole data, receiving the acoustic signal (the receiving by a receiver disposed within the internal diameter of a casing in the wellbore) converting the acoustic signal to a corresponding first electromagnetic signal, and inducing a second electromagnetic signal in a tubing responsive to the first electromagnetic signal. | 07-07-2011 |
20120018152 | FLUID CONTROL IN RESERVIOR FLUID SAMPLING TOOLS - A pumping system comprising: a probe to suction a fluid from a fluid reservoir; a pump in fluid communication with said probe; a sensor for detecting phase changes in said pumping system, said sensor in fluid communication with said probe or pump, said sensor generating a sensor signal; a fluid exit from said pumping system, said fluid exit being in fluid communication with said pump; and a variable force check valve located between said probe and said fluid exit. | 01-26-2012 |
20120072128 | Determining Fluid Density - The density of a fluid is determined using a vibratory resonant densitometer in an environment. The densitometer includes a tubular sample cavity and other densitometer parts. The method includes measuring a plurality of parameters characterizing the environment. The method further includes adjusting a model of the sample cavity using the measured parameters. The method further includes receiving a sample fluid into the sample cavity. The method further includes vibrating the sample cavity to obtain a vibration signal. The method further includes calculating the density of the sample fluid using the model and the vibration signal. | 03-22-2012 |
20120167692 | ENERGY INTENSITY TRANSFORMATION - Apparatus, systems, and methods may operate to receive incident energy within a chamber defining a first part of an interaction volume that attenuates the incident energy as a function of path length to provide attenuated energy. Additional activity may include simultaneously transforming the attenuated energy characterized by a substantially exponential intensity function into resultant energy characterized by a substantially polynomial intensity function. The transformation may be accomplished using an interacted energy transformation element that defines a second part of the interaction volume, the transformation element operating to intercept the attenuated energy along a plurality of path lengths. Other activity may include transmitting the resultant energy to a receiver. Additional apparatus, systems, and methods are disclosed. | 07-05-2012 |
20120234107 | NON-CONTACT TORQUE MEASUREMENT APPARATUS AND METHD - Disclosed is an apparatus and method for accurately measuring torque in a rotating shaft. The apparatus comprises axially spaced magnet-detector pairs, mounted to rotate with the shaft and means for sensing relative rotation between the magnets. | 09-20-2012 |
20130067995 | APPARATUS AND METHODS OF DETERMINING FLUID VISCOSITY - Various embodiments include apparatus and methods of determining the viscosity of a fluid downhole in a well. A parameter of a response signal, obtained from driving a tube containing a fluid with an excitation signal for vibrating the tube, can be collected while maintaining the tube in a vibrating mode. The parameter can be evaluated to measure the viscosity of the fluid. In various embodiments, the fluid viscosity may be measured in-situ downhole in the well. | 03-21-2013 |
20130113468 | METHOD AND APPARATUS FOR MEASURING LINEAR DISPLACMENT - For some embodiments, a system includes a moveable structure, moveable in at least a linear direction relative to a supporting structure, a magnetic field sensor assembly including a magnetic field sensor, and a magnet, wherein one of the magnet and the magnetic field sensor is coupled to the moveable structure, and wherein the other of the magnet and the magnetic field sensor assembly is coupled to the supporting structure, and wherein the magnetic field sensor assembly is configured to determine the relative position of the magnet to the magnetic field sensor. | 05-09-2013 |
20130180330 | FLUID DENSITOMETER WITH TEMPERATURE SENSOR TO PROVIDE TEMPERATURE CORRECTION - A sensor for measuring a density of a fluid is provided. The sensor ( | 07-18-2013 |
20130199286 | Non-Invasive Compressibility and In Situ Density Testing of a Fluid Sample in a Sealed Chamber - In situ density and compressibility of a fluid sample are determined for a fluid sample collected downhole. The density and compressibility of the fluid sample is determined by measuring a distance to a piston contained within the sample chamber using an external magnetic field sensor that senses a magnetic field emanating from a magnetic provided on the piston internal to the sample chamber. The testing is performed quickly and at the surface in a noninvasive fashion (i.e., without opening the sample chamber). | 08-08-2013 |
20130311099 | METHOD AND APPARATUS FOR EVALUATING FLUID SAMPLE CONTAMINATION BY USING MULTI SENSORS - A method of evaluating fluid sample contamination is disclosed. A formation tester tool is introduced into a wellbore. The formation tester tool comprises a sensor. Sensor data is acquired from the sensor and a contamination estimation is calculated. A remaining pump-out time required to reach a contamination threshold is then determined. | 11-21-2013 |
20140096957 | FLUID CONTROL IN RESERVOIR FLUID SAMPLILNG TOOLS - A pumping system includes a probe to suction a fluid from a fluid reservoir, a pump in fluid communication with the probe, and a sensor for detecting phase changes in said pumping system. The sensor is in fluid communication with the probe or pump and is operable to generate a sensor signal. The pumping system also includes a fluid exit from the pumping system that is in fluid communication with said pump, and a variable force check valve that is located between the probe and fluid exit. | 04-10-2014 |
20140111209 | METHODS AND SYSTEMS FOR ANALYZING FORMATION PROPERTIES WHEN PERFORMING SUBTERRANEAN OPERATIONS - A method of analyzing a subterranean formation is disclosed. A first signal is transmitted from a transmitter to the formation and a second signal which is a reflection of the first signal is received. A third signal, which is the second signal reversed in time, is then transmitted to the formation. A fourth signal which is a reflection of the third signal from the formation is then received and monitored. | 04-24-2014 |
20140195215 | MODELING WELLBORE FLUIDS - Techniques for modeling a wellbore fluid that includes a base fluid and one or more fluid additives includes identifying a target viscosity profile of the wellbore fluid; determining an initial set of values of the fluid additives that are based at least in part on the target viscosity profile; determining, with one or more non-linear predictive models, a computed viscosity profile of the wellbore fluid and a computed set of values of the fluid additives based, at least in part, on the initial set of values of the fluid additives; comparing the computed viscosity profile and at least one of the computed set of values with a specified criteria of the wellbore fluid; and preparing, based on the comparison, an output including the computed viscosity profile and at least one of the computed set of values of a resultant wellbore fluid. | 07-10-2014 |
20140339406 | Active Control of Thermal Effects on Optical Computing Devices - Disclosed are systems and methods for actively controlling the temperature of an integrated computational element used in an optical computing device in order to affect its performance. One method includes providing an integrated computational element configured detect a characteristic of a substance and provide a transmission profile via a detector corresponding to the characteristic, and controlling a temperature of the integrated computational element in order to maintain the transmission profile within an optimal operating range. | 11-20-2014 |
20140352953 | Integrated Computational Element Analysis of Production Fluid in Artificial Lift Operations - A downhole pump assembly for pumping production fluid to a surface of a well. The downhole pump assembly includes a fluid pump that is operable to pump the production fluid to the surface. An optical computing device having at least one integrated computational element and at least one detector. The at least one integrated computational element is configured to optically interact with the production fluid proximate the fluid pump and is configured to generate optically interacted light. The at least one detector is arranged to receive the optically interacted light and to generate an output signal corresponding to a characteristic of the production fluid. | 12-04-2014 |
20150015413 | DOWNHOLE TELEMETRY SYSTEMS AND METHODS WITH TIME-REVERSAL PRE-EQUALIZATION - Specific embodiments of disclosed downhole telemetry systems and methods employ time-reversal pre-equalization. One downhole telemetry system embodiment includes an acoustic transducer and a digital signal processor. The acoustic transducer transmits an acoustic signal to a distant receiver via a string of drillpipes connected by tool joints. The digital signal processor drives the acoustic transducer with an electrical signal that represents modulated digital data convolved with a time-reversed channel response. Due to the use of time-reversal pre-equalization, the received signal exhibits substantially reduced intersymbol interference. | 01-15-2015 |
20150070000 | SINGLE MAGNET FLUID DENSITOMETER - An instrument for determining fluid properties is provided. The instrument ( | 03-12-2015 |
20150077265 | TELEMETRY ON TUBING - In some embodiments, an apparatus and a system, as well as a method and an article, may operate to program a first acoustic repeater to transmit information at a first operating frequency; to couple the first acoustic repeater circumferentially around a coiled tubing portion, an inner diameter of the first acoustic repeater being about equal to an outer diameter of the coiled tubing portion; to program a second acoustic repeater to receive information transmitted by the first acoustic repeater; and to receive sensor information transmitted at the first operating frequency by the first acoustic repeater and relayed by the second acoustic repeater, the second acoustic repeater being coupled to the coiled tubing portion uphole from the first acoustic repeater. Additional apparatus, systems, and methods are disclosed. | 03-19-2015 |
20150101404 | SENSOR CHARACTERIZATION APPARATUS, METHODS, AND SYSTEMS - In some embodiments, an apparatus and a system, as well as a method and an article, may operate to receive a vibration signal having a frequency and a characteristic (e.g., voltage) proportional to the vibration amplitude of a tube in a vibrating tube density sensor. Further activity may include transmitting the density of a fluid flowing through the tube based on the frequency and an elastic modulus of the tube determined by the value of the characteristic. Additional apparatus, systems, and methods are described. | 04-16-2015 |