Gao, MD
Changshou Gao, Gaithersburg, MD US
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20120213705 | ENGINEERED Fc REGIONS FOR SITE-SPECIFIC CONJUGATION - Fc regions useful for site-specific conjugation to a variety of agents are provided. Methods for the design, preparation, screening, selection and use of such Fc regions are also provided. | 08-23-2012 |
20130231463 | Cell Display Of Antibody Libraries - The present invention relates to a viral vector encoding for a library of antibodies or antibody fragments that are displayed on the cell membrane when expressed in a cell. The present invention provides cells comprising the viral vector nucleic acids and methods of screening the libraries for antibodies or antibody fragments with desired characteristics. | 09-05-2013 |
20130295098 | MULTISPECIFIC EPITOPE BINDING PROTEINS AND USES THEREOF - The present invention relates to multispecific epitope binding proteins, methods of making, and uses thereof in the prevention, management, treatment or diagnosis of acute or chronic diseases. | 11-07-2013 |
20140148392 | HSA-Related Compositions And Methods Of Use - Provided are human serum albumin (HSA) compositions with improved properties over native HSA. | 05-29-2014 |
20140155581 | Methods For Making Multimeric Polypeptides - Detailed herein are contiguous, multimeric, multispecific polypeptides, nucleic acids encoding such polypeptides, and methods for making such polypeptides and nucleic acids. | 06-05-2014 |
20140302038 | MULTISPECIFIC AND MULTIVALENT BINDING PROTEINS AND USES THEREOF - The disclosure generally provides proteins that bind two epitopes (e.g., a first and a second epitope) and that are bivalent for binding to each of the first and second epitopes. The disclosure also provides compositions comprising such proteins, nucleic acid molecules encoding such proteins and methods of making and using such proteins. | 10-09-2014 |
20150023966 | COMBINATION THERAPIES USING ANTI-PSEUDOMONAS PSL AND PCRV BINDING MOLECULES - This disclosure relates to combination therapies comprising anti- | 01-22-2015 |
20150284450 | COMBINATION THERAPIES USING ANTI-PSEUDOMONAS PSL AND PCRV BINDING MOLECULES - The disclosure relates to combination therapies comprising anti- | 10-08-2015 |
Changsou Gao, Potomac, MD US
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20080311122 | Antagonists of Hmgb1 and/or Rage and Methods of Use Thereof - Compositions and methods are disclosed for inhibiting the release of a proinflammatory cytokine from a vertebrate cell, and for inhibiting an inflammatory cytokine cascade in a patient. The compositions comprise, for example, high affinity antibodies that specifically bind HMG1 and antigenic fragments thereof. The high affinity antibodies of the present invention and pharmaceutical compositions comprising the same are useful for many purposes, for example, as therapeutics against a wide range of inflammatory diseases and disorders such as sepsis, rheumatoid arthritis, peritonitis, Crohn s disease, reperfusion injury, septicemia, endotoxic shock, cystic fibrosis, endocarditis, lupus, psoriasis, psoriatic arthritis, arthritis, anaphylactic shock, organ ischemia, reperfusion injury, and allograft rejection. In addition, the high affinity antibodies of the present inventions are useful as diagnostic antibodies. | 12-18-2008 |
20090304721 | TOXIN CONJUGATED EPH RECEPTOR ANTIBODIES - The present invention relates to compositions and methods for inducing cell death or stasis in cancer cells or other hyperproliferative cells using anti-EphA2 or anti-EphA4 antibodies conjugated to toxins. | 12-10-2009 |
Cuihua Gao, Gaithersburg, MD US
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20150023966 | COMBINATION THERAPIES USING ANTI-PSEUDOMONAS PSL AND PCRV BINDING MOLECULES - This disclosure relates to combination therapies comprising anti- | 01-22-2015 |
Donghong Gao, Clarksville, MD US
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20120220320 | Alphanumeric address mapping for non-homogeneous short message networks - Text messages with alphanumeric addresses are delivered to mobiles and external short message entities (ESMEs) which do not support alphanumeric addressing, providing meaningful fallback handling. Additionally, the invention enables delivery of SMPP messages from ESME or SMPP networks which can only originate numeric addresses, yet provide for mapping to alphanumeric addresses for delivery to the mobile. A two-way mapping is provided between alphanumeric addresses and SMS short-codes to enable delivery of text messages with alphanumeric addressing in networks which contain mobiles and/or ESME's that lack support of alphanumeric addressing. An ESME can send a text message using an alphanumeric origination address, without knowing which handsets support the capability, and which do not, or whether handsets are on CDMA, or GSM, or UMTS, or networks, or can continue to send using a numeric origination address. The SMSC provides conversions to alphanumeric addresses on behalf of the ESME and the mobile. | 08-30-2012 |
20130045711 | Prepaid Short Message Services Revenue Capture - A prepaid messaging solution that utilizes a pre-delivery debit query to tariff a short message, coupled with an additional debit query performed once necessary billing information has been acquired. A short message is tariffed prior to message delivery via a pre-delivery debit query to a prepaid server. During message delivery, the prepaid server is queried a second time, following the HLR query performed by the Short Message Service Center (SMSC). This subsequent debit query bills a subscriber for any additional service fees discovered throughout message delivery, e.g., international/roaming fees, etc. If either the pre-delivery debit query or the subsequent debit query indicates that a subscriber has insufficient account balance to deliver a short message, the message is prevented from being delivered. If a message is dropped due to lack of account balance, any funds debited throughout the attempted message delivery may be credited back to the subscriber's prepaid account. | 02-21-2013 |
20140006269 | Prepaid Short Message Services Revenue Capture | 01-02-2014 |
20140357225 | Prepaid Short Message Services Revenue Capture - A prepaid messaging solution that utilizes a pre-delivery debit query to tariff a short message, coupled with an additional debit query performed once necessary billing information has been acquired. A short message is tariffed prior to message delivery via a pre-delivery debit query to a prepaid server. During message delivery, the prepaid server is queried a second time, following the HLR query performed by the Short Message Service Center (SMSC). This subsequent debit query bills a subscriber for any additional service fees discovered throughout message delivery, e.g., international/roaming fees, etc. If either the pre-delivery debit query or the subsequent debit query indicates that a subscriber has insufficient account balance to deliver a short message, the message is prevented from being delivered. If a message is dropped due to lack of account balance, any funds debited throughout the attempted message delivery may be credited back to the subscriber's prepaid account. | 12-04-2014 |
20150382163 | Alphanumeric Address Mapping for Non-Homogeneous Short Message Networks - Text messages with alphanumeric addresses are delivered to mobiles and external short message entities (ESMEs) which do not support alphanumeric addressing, providing meaningful fallback handling. Additionally, the invention enables delivery of SMPP messages from ESME or SMPP networks which can only originate numeric addresses, yet provide for mapping to alphanumeric addresses for delivery to the mobile. A two-way mapping is provided between alphanumeric addresses and SMS short-codes to enable delivery of text messages with alphanumeric addressing in networks which contain mobiles and/or ESME's that lack support of alphanumeric addressing. | 12-31-2015 |
Fang Gao, Rockville, MD US
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20100067909 | TECHNIQUES FOR ENSURING SYNCHRONIZED PROCESSING AT REMOTE FIBRE CHANNEL AND FIBRE CONNECTIVITY NETWORKS - Techniques described use Generic Framing Procedure (GFP) to transport data across an optical transport network between near and far Fibre Channel (FC) or Fibre Connectivity (FICON) local area optical networks. Each FC/FICON edge node (FCE) on an edge of the optical transport network has multiple modes for processing FC/FICON frames transported across the optical transport network. The techniques include receiving, at a near FCE from a far FCE, a GFP control plane message that includes a mode field that holds data that indicates a far mode, wherein the far mode is used at the far FCE. It is determined whether a near mode used by the near FCE matches the far mode based on the mode field. If it is determined that they do not match, then an alert is caused. These techniques allow software to utilize existing GFP chips in FCE that use optional processing, such as distance extension. | 03-18-2010 |
Rui Gao, Bethesda, MD US
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20130039908 | PROGNOSTIC MARKERS AND METHODS FOR PROSTATE CANCER - The present invention relates to methods and compositions for the diagnosis, prognosis and treatment of neoplastic disorders. Some embodiments include methods, compositions, and kits for the prognosis and treatment of prostate cancer. | 02-14-2013 |
Taishan Gao, New Market, MD US
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20090139454 | FORAGING FEEDING SYSTEM FOR CAPTIVE BIRDS - A feeding system for captive birds combines the activity of foraging with feeding in a manner that can be easily managed and used by the bird's owner or caretaker. The system includes a disposable feeder box made of frangible edible material for storing food and a mounting system for mounting the box to an inside surface of a bird cage. | 06-04-2009 |
Tia Gao, Rockville, MD US
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20160132868 | SAVING MERCHANT ARTIFACTS TO A VIRTUAL WALLET - A virtual wallet system provides embedded controls to a merchant for association and display with merchant artifacts on a merchant interface. Merchant artifacts may include begin-of-purchase flow items such as coupons, and end-of-purchase flow item such as tickets. When the embedded control displayed on the merchant interface is selected by a user, a save artifact request is communicated to a virtual wallet server allowing the user to instantly save an instance of the merchant artifact to the user's corresponding virtual wallet account. | 05-12-2016 |
Tia Gao, Ellicott City, MD US
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20080228045 | Multiprotocol Wireless Medical Monitors and Systems - A wireless medical monitoring system and medical monitoring devices adapted to communicate using a plurality of wireless protocols and networks. For each transmission of data, a wireless protocol or network is selected based on the properties of the available protocols and networks and the nature of the data that is to be transmitted. Thus, the medical system and devices can move seamlessly from one context and location to another. The medical devices may also include additional features, such as detection of improperly positioned or disconnected sensors and auditory and/or visual prompting of the patient to correct the problem. In some embodiments, the medical monitoring devices may comprise body area networks of individual sensors communicating and cooperating with one another wirelessly. | 09-18-2008 |
20090069642 | Wearable Wireless Electronic Patient Data Communications and Physiological Monitoring Device - Described are patient data communication devices that may be used as wearable patient monitors. The devices are adapted to accept essentially any type of data from essentially any data source, and are reconfigurable, such that each device can determine which data inputs and outputs should be active, and can reconfigure itself based on new configuration instructions. The devices include wireless transceiver units that allow them to form networks, and particularly mesh networks, with other devices. In a mesh network, any one of the devices may serve as a data source, a data forwarder, or a data sink, and the processor of each device may determine whether data should be outputted, displayed, or processed on the local device or on a remote device in the network. Data from other devices in a mesh network may be accepted selectively, depending on the number of hops between the sending and receiving devices. | 03-12-2009 |
20100171611 | Sensor-Based Adaptive Methods for Wearable Devices - The present disclosure is directed towards apparatuses, systems and methods for providing improved sensor-based patient monitoring and tracking. In accordance with one aspect, a method is provided for adjusting a vital sign alarm threshold of a vital status sensor as a function of a patient's GPS data, which may comprise: altitude data, velocity data, and position data. In accordance with another aspect, a method is provided for adjusting one or more alarm detection parameters based in part on a patient's calculated heart rate variability (HRV) data. According to yet another aspect, an electronic triage tag is configured to include a colored card insertion region for inserting a colored card for preventing the device from being inadvertently activated, an LCD screen and a series of LEDs for displaying the triage status of a patient (red, yellow, green, black). | 07-08-2010 |
Wei Dong Gao, Woodstock, MD US
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20120231482 | METHOD, KIT OR DIAGNOSTIC FOR THE DETECTION OF REAGENTS WHICH INDUCE ALTERED CONTRACTILITY - A method of screening for compounds that enhance or depress contractile function, based on measuring the formation of heterodimers of contractile fibers (e.g. Tm and actin, myosin heavy and myosin light chains), for example through disulfide bond formation. Diagnostic and prognostic methods and kits are also provided. | 09-13-2012 |
Xiangqun Gao, Joppa, MD US
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20090017002 | PREVENTION AND TREATMENT OF OXIDATIVE STRESS DISORDERS BY GLUTATHIONE AND PHASE II DETOXIFICATION ENZYMES - The present invention generally relates to the field of treating oxidative stress disorders by administering a pharmaceutically effective amount of a compound that elevates the intracellular levels of glutathone or intracelluar levels of at least one Phase II detoxification enzyme in animal tissue. The present invention also relates to the field of protecting a subject from oxidative stress disorders by administering a pharmaceutically effective amount of a compound that elevates the intracellular levels of glutathone or intracelluar levels of at least one Phase II detoxification enzyme in the subject. The present invention also relates to a pharmaceutical composition useful for the treatment of oxidative stress disorders. | 01-15-2009 |
20130157965 | Prevention and Treatment of Oxidative Stress Disorders by Glutathione and Phase II Detoxification Enzymes - The present invention generally relates to the field of treating oxidative stress disorders by administering a pharmaceutically effective amount of a compound that elevates the intracellular levels of glutathone or intracelluar levels of at least one Phase II detoxification enzyme in animal tissue. The present invention also relates to the field of protecting a subject from oxidative stress disorders by administering a pharmaceutically effective amount of a compound that elevates the intracellular levels of glutathone or intracelluar levels of at least one Phase II detoxification enzyme in the subject. The present invention also relates to a pharmaceutical composition useful for the treatment of oxidative stress disorders. | 06-20-2013 |
Xinxin Gao, Baltimore, MD US
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20100202970 | INTRACELLULAR REPORTERS - The invention provides a variety of molecular tools for use in live-cell tracking of activities of biomolecules and in high-throughput drug screening. | 08-12-2010 |
20110275103 | EMISSION RATIOMETRIC REPORTERS OF MEMBRANE PDK1 ACTIVATION - Phosphoinositide-dependent kinase 1 (PDK1) activity reporters can be used in high throughput assays for drug screening. | 11-10-2011 |
Yixin Gao, Baltimore, MD US
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20140378995 | METHOD AND SYSTEM FOR ANALYZING A TASK TRAJECTORY - A computer-implemented method of analyzing a sample task trajectory including obtaining, with one or more computers, position information of an instrument in the sample task trajectory, obtaining, with the one or more computers, pose information of the instrument in the sample task trajectory, comparing, with the one or more computers, the position information and the pose information for the sample task trajectory with reference position information and reference pose information of the instrument for a reference task trajectory, determining, with the one or more computers, a skill assessment for the sample task trajectory based on the comparison, and outputting, with the one or more computers, the determined skill assessment for the sample task trajectory. | 12-25-2014 |
Yong Gao, Germantown, MD US
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20080276282 | METHOD, SYSTEM AND COMPUTER PROGRAM PRODUCT FOR EFFICIENT STORAGE OF DATA - A method, system and computer program product for efficient storage of data for use by an application, including a set top box. The set top box including a physical memory, a bulk storage device, and a memory management unit (MMU) coupled between the application and the physical memory and the bulk storage device. The physical memory and the bulk storage device are configured to store the data. The MMU is configured to translate a virtual address provided by the application to a physical address used by one of the physical memory and the bulk storage device. | 11-06-2008 |
Zhan-Guo Gao, Rockville, MD US
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20090054476 | A3 Adenosine receptor allosteric modulators - The present invention relates to allosteric modulation of A | 02-26-2009 |
20130197025 | A3 ADENOSINE RECEPTOR ALLOSTERIC MODULATORS - The claimed subject matter relates to allosteric modulation of A | 08-01-2013 |