Patent application number | Description | Published |
20100142766 | Image Analysis - Systems and methods of processing a retinal input image to identify an area representing a predetermined feature. One method comprises processing said retinal input image to generate a plurality of images, each of said plurality of images having been scaled by a respective associated scaling factor, and each of said plurality of images having been subjected to a morphological closing operation with a two-dimensional structuring element arranged to affect the image substantially equally in at least two perpendicular directions. The plurality of images are processed to identify said area representing said predetermined feature. | 06-10-2010 |
20100142767 | Image Analysis - Systems and methods of processing a retinal input image to identify an area representing a predetermined feature. One method comprises processing said retinal input image to generate a plurality of images, each of said plurality of images having been scaled by a respective associated scaling factor, and each of said plurality of images having been subjected to a morphological closing operation with a two-dimensional structuring element arranged to affect the image substantially equally in at least two perpendicular directions. The plurality of images are processed to identify said area representing said predetermined feature. | 06-10-2010 |
20120027275 | DISEASE DETERMINATION - A method of generating output data providing an indication of the presence or absence of disease from at least one retinal image of a patient. The method comprises receiving first data associated with detection of a first lesion type in the at least one image, receiving second data associated with detection of a second lesion type in the at least one image, and receiving third data associated with detection of a third lesion type in the at least one image, wherein at least one of said first data, said second data and said third data is a quantitative indication associated with detection of the respective lesion type in said image. The first data, second data and third data are combined to generate the output data providing an indication of the presence or absence of disease. | 02-02-2012 |
Patent application number | Description | Published |
20100168522 | SURGICAL ACCESS ASSEMBLY - A surgical access assembly configured and dimensioned for positioning within an intercostal space defined between a patient's adjacent ribs to facilitate passage of a surgical instrument into an internal work site. The surgical access assembly includes a body portion that may be either partially or wholly formed from a resilient material such that the surgical access assembly is resiliently deformable to facilitate conformity with the intercostal space in order to minimize the application of force to the patient's tissue upon insertion and removal of the access assembly and manipulation of the surgical instrument. | 07-01-2010 |
20120083797 | SURGICAL RETRIEVAL APPARATUS - A surgical retrieval apparatus includes a housing having an elongated sleeve extending therefrom that, together, cooperate to define a lumen extending therethrough. A shaft having an end effector assembly disposed at a distal end thereof is selectively translatable between a first position, wherein the end effector assembly is disposed within the sleeve, and a second position, wherein the end effector assembly extends distally from the sleeve. A specimen retrieval bag is releasably coupled to the end effector assembly and is deployable to an extended position upon movement of the end effector assembly from the first to the second position. | 04-05-2012 |
20140222016 | SURGICAL RETRIEVAL APPARATUS FOR THORACIC PROCEDURES - A surgical retrieval apparatus includes a housing defining a longitudinal axis and including an elongated sleeve extending distally therefrom. The housing and the elongated sleeve cooperate to define a lumen extending longitudinally therethrough. A shaft having an end effector disposed at a distal end thereof is selectively translatable between a first position, wherein the end effector is disposed within the elongated sleeve, and a second position, wherein the shaft is translated through the lumen such that the end effector extends distally from the elongated sleeve. An articulation mechanism operably coupled to the end effector is configured for articulating the end effector relative to the longitudinal axis. A specimen retrieval bag is coupled to the end effector and is deployed therefrom upon movement of the end effector from the first position to the second position. | 08-07-2014 |
Patent application number | Description | Published |
20110190779 | SURGICAL RETRIEVAL APPARATUS - A surgical retrieval apparatus having an elongate member and a support member extending from the elongate member movable between a collapsed insertion position and an expanded position. A retrieval bag extends from the support member and has a first end and a closed second end, the first end movable to an open configuration when the support member moves to the expanded position. A net is positioned within the retrieval bag and detachably connected thereto. | 08-04-2011 |
20110190781 | SURGICAL RETRIEVAL APPARATUS - A surgical retrieval apparatus includes an elongate flexible tubular member having a distal opening and a lumen and a support member having a chamber formed therein in fluid communication with the tubular member and movable from a first position to a second expanded position in response to introduction of fluid into the chamber. A retrieval bag extends from the support member and has a first end and a closed second end. The first end of the retrieval bag is movable to an open configuration when the expandable member transitions from the first position to the second expanded position. | 08-04-2011 |
20110190782 | SURGICAL RETRIEVAL APPARATUS - A surgical retrieval apparatus includes an elongate tubular member having a drive rod slidably disposed therein. A support member is operably coupled to a distal end of the drive rod. A pouch is attached to the support member and has a closed end and an open end. The pouch is securely coupled to the support member. | 08-04-2011 |
20110264091 | APPARATUS AND METHOD FOR SEALING SPECIMEN FOR RETRIEVAL - A method for modifying a tissue specimen includes providing a specimen modifying apparatus configured to modify the specimen to thereby prevent seeding from the specimen. The specimen modifying apparatus is inserted through an opening in tissue and positioned adjacent the tissue specimen to be modified. The tissue modifying apparatus is activated to modify the tissue specimen to thereby inhibit seeding from the tissue specimen. | 10-27-2011 |
20110270265 | SYSTEM AND METHOD FOR REMOVING EXCISED TISSUE - A method and system for removing tissue from a body cavity is provided. The system includes a retrieval bag that is insertable through a first incision in tissue and includes open and closed ends. A surgical instrument is insertable into the body cavity and configured to grasp and excise a sample/specimen from within the body cavity and selectively substantially seal the retrieval bag. A fluid circulator in fluid communication with the surgical instrument and the open end of the retrieval bag is configured to evacuate gaseous matter from within the body cavity and into the open end of the retrieval bag such that the retrieval bag substantially encircles the excised tissue specimen. | 11-03-2011 |
20120083795 | SPECIMEN RETRIEVAL DEVICE - A specimen retrieval device is provided. The specimen retrieval device includes an applicator. A specimen retrieval bag is operably disposed within the applicator and deployable therefrom. The specimen retrieval bag includes a conduit configured to evacuate air from the specimen retrieval bag. | 04-05-2012 |
20120083796 | SPECIMEN RETRIEVAL APPARATUS - A specimen retrieval apparatus includes a housing having an elongated tubular member extending distally therefrom. The elongated tubular member defines a longitudinal axis. An end effector assembly is coupled to a distal end of the elongated tubular member. The end effector assembly is configured to retain a specimen retrieval bag thereon. An articulation mechanism is operatively coupled to the elongated tubular member and the end effector assembly. The articulation mechanism is configured for selectively articulating the end effector assembly with respect to the longitudinal axis of the elongated tubular member. | 04-05-2012 |
20120101337 | ENDOSCOPE CLEANER - An instrument for cleaning a scope lens having an elongated sheath having proximal and distal end portions and a sheath interior and exterior. The sheath interior is dimensioned and configured to slidingly receive a scope therein. A fluid conduit transports fluid and has a fluid discharge opening to deliver fluid to the lens of the scope, the conduit coupled to the sheath exterior. | 04-26-2012 |
20120101338 | ENDOSCOPE WIPER BLADE CLEANER - A minimally invasive surgical instrument including a viewing instrument and a wiper mechanism configured and adapted to clean a lens of the viewing instrument. The wiper mechanism includes a wiper that is configured and adapted to contact and translate across a surface of the lens. An actuator moves the wiper across the lens to clean the lens. | 04-26-2012 |
20120179165 | SURGICAL RETRIEVAL APPARATUS FOR THORACIC PROCEDURES - A surgical retrieval apparatus includes a housing defining a longitudinal axis and including an elongated sleeve extending distally therefrom. The housing and the elongated sleeve cooperate to define a lumen extending longitudinally therethrough. A shaft having an end effector disposed at a distal end thereof is selectively translatable between a first position, wherein the end effector is disposed within the elongated sleeve, and a second position, wherein the shaft is translated through the lumen such that the end effector extends distally from the elongated sleeve. An articulation mechanism operably coupled to the end effector is configured for articulating the end effector relative to the longitudinal axis. A specimen retrieval bag is coupled to the end effector and is deployed therefrom upon movement of the end effector from the first position to the second position. | 07-12-2012 |
20130150670 | THORACIC SCOPE PORT CLEANER - An instrument for cleaning a lens of a scope includes an elongated sheath and a cleaning portion. The elongated sheath defines a lumen dimensioned and configured to slidingly receive the scope therein. The cleaning portion is positioned in a distal portion of the lumen. The cleaning portion includes a membrane formed from an elastic material. The membrane includes one or more openings to facilitate translation of the scope through the membrane. | 06-13-2013 |
20140046337 | SURGICAL RETRIEVAL APPARATUS - A method of retrieving a tissue specimen comprising inserting a surgical retrieval apparatus through an opening in a patient's skin, the surgical retrieval apparatus including a support member and a retrieval bag extending from the support member and having an opening to receive the tissue specimen. A net is introduced into the retrieval bag and placed over the tissue specimen. The net and retrieval bag are removed from the patient's body to remove the tissue specimen. | 02-13-2014 |
Patent application number | Description | Published |
20090274773 | ANTIPROLIFERATIVE COMBINATION COMPRISING CYC-682 AND A CYTOTOXIC AGENT - A first aspect of the invention relates to a combination comprising 2′-cyano-2′-deoxy-N4-palmitoyl-1-beta-D-arabi-nofuranosyl-cytosine, or a metabolite thereof, or a pharmaceutically acceptable salt thereof, and a cytotoxic agent selected from (a) a vinca alkaloid; (b) a taxane; (c) a cytosine analogue; (d) an anthracycline; and (e) a platinum antineoplastic agent. A second aspect of the invention relates to a pharmaceutical product comprising the above combination as a combined preparation for simultaneous, sequential or separate use in therapy. A third aspect of the invention relates to a method for treating a proliferative disorder, said method comprising simultaneously, sequentially or separately administering the above combination. | 11-05-2009 |
20090306098 | COMBINATION OF ROSCOVITINE AND A HDCA INHIBITOR TO TREAT PROLIFERATIVE DISEASES - A first aspect of the invention relates to a combination comprising roscovitine, or a pharmaceutically acceptable salt thereof, and a HDAC inhibitor selected from sodium butyrate, or a prodrug thereof, suberoylanilide hydroxamic acid (SAHA), sodium valproate and trichostatin A (TSA). A second aspect of the invention relates to a pharmaceutical product comprising roscovitine, or a pharmaceutically acceptable salt thereof, and a HDAC inhibitor selected from sodium butyrate, or a prodrug thereof, suberoylanilide hydroxamic acid (SAHA), sodium valproate and trichostatin A (TSA) as a combined preparation for simultaneous, sequential or separate use in therapy. A third aspect of the invention relates to a method for treating a proliferative disorder, said method comprising simultaneously, sequentially or separately administering roscovitine, or a pharmaceutically acceptable salt thereof, and a HDAC inhibitor selected from sodium butyrate, or a prodrug thereof, suberoylanilide hydroxamic acid (SAHA), sodium valproate and trichostatin A (TSA) to a subject. | 12-10-2009 |
20100069291 | COMBINATION COMPRISING CNDAC (2'-CYANO-2'-DEOXY-N4-PALMITOYL-1-BETA-D-ARABINOFURANOSYL-CYTOSINE) AND A CYTOTOXIC AGENT - A first aspect of the invention relates to a combination comprising 2′-cyano-2′-deoxy-N | 03-18-2010 |
20100143350 | COMBINATION OF A PURINE-BASED CDK INHIBITOR WITH A TYROSINE KINASE INHIBITOR AND USE THEREOF IN THE TREATMENT OF PROLIFERATIVE DISORDERS - The present invention relates to combination comprising (i) an ErbB inhibitor; and (ii) a CDK inhibitor, or a pharmaceutically acceptable salt thereof, selected from: (a) roscovitine; (b) 3-{9-isopropyl-6-[(pyridin-3-ylmethyl)-amino]-9H-purin-2-ylamino}-2-methyl-pentan-2-ol; (c) 3-{9-isopropyl-6-[(pyridin-3-ylmethyl)-amino]-9H-purin-2-ylamino}-pentan-2-ol; and (d) (2R,3S-3-(6-((4,6-dimethylpyridin-3-ylmethylamino)-9-isopropyl-9H-purin-2-ylamino)pentan-2-ol. | 06-10-2010 |
Patent application number | Description | Published |
20110207692 | COMBINATIONS OF SAPACITABINE OR CNDAC WITH DNA METHYLTRANSFERASE INHIBITORS SUCH AS DECITABINE AND PROCAINE - A first aspect of the invention relates to a combination comprising a DNA methyltransferase inhibitor and 1-(2-C-cyano-2-dioxy-β-D-arabino-pentofuranosyl)-N4-palmitoyl cytosine, or a metabolite thereof. A second aspect of the invention relates to a pharmaceutical product comprising a DNA methyltransferase inhibitor and 1-(2-C-cyano-2-dioxy-β-D-arabino-pentofuranosyl)-N4-palmitoyl cytosine, or a metabolite thereof, as a combined preparation for simultaneous, sequential or separate use in therapy. A third aspect of the invention relates to a method of treating a proliferative disorder, said method comprising simultaneously, sequentially or separately administering a DNA methyltransferase inhibitor and 1-(2-C-cyano-2-dioxy-β-D-arabino-pentofuranosyl)-N4-palmitoyl cytosine, or a metabolite thereof, to a subject. | 08-25-2011 |
20130196938 | COMBINATION COMPRISING CNDAC (2'-CYANO-2'-DEOXY-N4-PALMITOYL-1-BETA-D-ARABINOFURANOSYL-CYTOSINE) AND A CYTOTOXIC AGENT - A first aspect of the invention relates to a combination comprising 2′-cyano-2′-deoxy-N | 08-01-2013 |
20140100187 | COMBINATIONS OF SAPACITABINE OR CNDAC WITH DNA METHYLTRANSFERASE INHIBITORS SUCH AS DECITABINE AND PROCAINE - A first aspect of the invention relates to a combination comprising a DNA methyltransferase inhibitor and 1-(2-C-cyano-2-dioxy-β-D-arabino-pentofuranosyl)-N4-palmitoyl cytosine, or a metabolite thereof. A second aspect of the invention relates to a pharmaceutical product comprising a DNA methyltransferase inhibitor and 1-(2-C-cyano-2-dioxy-β-D-arabino-pentofuranosyl)-N4-palmitoyl cytosine, or a metabolite thereof, as a combined preparation for simultaneous, sequential or separate use in therapy. A third aspect of the invention relates to a method of treating a proliferative disorder, said method comprising simultaneously, sequentially or separately administering a DNA methyltransferase inhibitor and 1-(2-C-cyano-2-dioxy-β-D-arabino-pentofuranosyl)-N4-palmitoyl cytosine, or a metabolite thereof, to a subject. | 04-10-2014 |
Patent application number | Description | Published |
20090102713 | Geolocation Methods and Apparatus - Methods and associated apparatus and programs for computers for operating geolocation devices are provided. The methods include determining the duration of a time interval during which the device is configured to remain active, responsive to a comparison between an estimate of benefit of remaining on for that time interval and an estimate of cost of remaining on for that time interval. The estimates of cost and benefit may be determined in response to user-selected parameters where by the end-user may effect a trade-off between battery life and receiver sensitivity. The methods also include varying the maximum duration of each listening period whereby to conserve battery power. | 04-23-2009 |
20140292568 | RADIOBEACON STATIONS, USER DEVICES, LOCATION DETERMINATION SYSTEMS, METHODS FOR CONTROLLING A RADIOBEACON STATION, METHODS FOR CONTROLLING A USER DEVICE, AND LOCATION DETERMINATION METHODS - A radiobeacon station is described comprising: a satellite receiver configured to receive satellite navigation data from a satellite; a timing circuit configured to determine a timing scheme based on the satellite navigation data; and a terrestrial transmitter configured to transmit a plurality of beacon signals based on the determined timing scheme. | 10-02-2014 |
20140375494 | PEDESTRIAN POSITIONING IN HIGH-REFLECTION ENVIRONMENTS - A positioning system operates by first determining that a user is pedestrian, and then estimating a speed of the user. Having tracked a first signal from one radio transmitter whose position is known, the system attempts to detect additional signals from the one transmitter, in a search space such that the first signal and the or each additional signal are consistent with the estimated speed of the user and with one or more of the signals having been reflected off a reflector in the vicinity of the user. One or more detected additional signals from the one transmitter are then tracked, and candidate measurements, derived from the first signal and the one or more detected additional signals, are provided for use when estimating the position and/or velocity of the user. | 12-25-2014 |
20140375495 | Vehicle Positioning in High-Reflection Environments - A positioning system obtains an estimate of the heading of a body whose position or velocity is to be estimated, for example from a heading sensor such as a gyroscope or accelerometer. Respective signals are tracked from a plurality of transmitters, and a respective Doppler measurement is obtained from each of said tracked signals. For each of the tracked signals, a speed of the body is estimated using the estimate of the heading of the body and the respective Doppler measurement. It is then determined whether the estimated speed of the body is consistent with the signal having been received along a direct path from the transmitter. Signals that provide information about the speed of the body that is inconsistent with the signal having been received along a direct path from the transmitter are then disregarded when estimating the position or velocity of the body. | 12-25-2014 |
Patent application number | Description | Published |
20100230451 | ROOF BAR FOR A MOTOR VEHICLE - A roof bar ( | 09-16-2010 |
20100230452 | ROOF BAR FOR A MOTOR VEHICLE - A roof bar ( | 09-16-2010 |
20100230453 | ROOF BAR FOR A MOTOR VEHICLE - A roof bar ( | 09-16-2010 |
20110103926 | Vehicle Storage/Loading System for Sheets - A motor vehicle having an assembly for loading sheet material includes a cargo area having a loading opening and a bulkhead located at an opposite end of the cargo area from the loading opening. Also included is a passenger compartment located at a forward region of the vehicle. Further included is at least one fixed end stop located proximate a rear area of the cargo area. Yet further included is at least one load assist strip, where a first end of the strip is mounted to the bulkhead, wherein the strip extends rearward to a second end of the strip that is mounted to the end stop. | 05-05-2011 |
20110148134 | MOVABLE BULKHEAD SYSTEM TO INCREASE LOAD CAPACITY OF A VEHICLE - A moveable bulkhead | 06-23-2011 |
20140153163 | COMBINED STORAGE AND DOCKING UNIT FOR A PORTABLE ELECTRONIC DEVICE - A combined storage and docking unit for attachment to the instrument panel of a motor vehicle is disclosed in which a portable electronic device such as an MP3 player or GPS navigation device can be held in a display position by clamping it between lid and storage box parts of the combined storage and docking unit. The storage box includes a trough shaped portion in which the portable electronic device can be stowed if it is not required to be used. The combined storage and docking unit is of a simple construction and allows portable electronic devices of differing size and shape to be accommodated. | 06-05-2014 |
20150258943 | COMBINED STORAGE AND DOCKING UNIT FOR A PORTABLE ELECTRONIC DEVICE - A combined storage and docking unit for attachment to the instrument panel of a motor vehicle is disclosed in which a portable electronic device such as an MP3 player or GPS navigation device can be held in a display position by clamping it between lid and storage box parts of the combined storage and docking unit. The storage box includes a trough shaped portion in which the portable electronic device can be stowed if it is not required to be used. The storage box also includes a lid hingedly connected thereto. A lid opening mechanism includes an arm fixed to a shaft. A drive cable is connected to the arm and to a spring on opposing ends. A pulley is configured to guide the drive cable from the arm to the spring, wherein the shaft is rotatably supported by a shaft bracket. | 09-17-2015 |