Epperly
Carl E. Epperly, Manchester, MO US
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20140046859 | Business to Business Computer System for Communicating and Processing Rental Car Reservations Using Web Services - A system, method, and computer program product are disclosed whereby a business partner computer system interfaces with a rental vehicle reservation management computer system via a web service connector. The web service connector can be configured to (1) receive, via a network, a document, the document comprising a web service request by a computer system of a business partner for a rental vehicle transaction with respect to a replacement rental vehicle reservation, (2) process the received document in accordance with a web service specification document to create one or more data objects having a format supported by a rental vehicle reservation management software program, and (3) communicate the one or more data objects to the rental vehicle reservation management software program for automatic processing thereby of the one or more data objects for management of the replacement rental vehicle reservation in accordance with the request. | 02-13-2014 |
Mark S. Epperly, Sherrard, IL US
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20080205978 | Cable actuated pin latching mechanism with automatic cable tension and pin release features - A cable actuated pin latching mechanism adapted for releasably connecting a header to a feeder of a combine, which automatically maintains predetermined tension conditions on the cable during normal latching and unlatching operation, and when an actuator of the mechanism is held in an unlatch position with the latch pin stuck or restrained, applies and maintains a tension force for releasing the pin, for instance, to enable a user to move to the operator cab to operate lift, tilt and/or other controls, as required for freeing the pin. | 08-28-2008 |
20080207286 | Rotor for a threshing system of an agricultural combine and method of making the same - A rotor for a threshing system of an agricultural combine and method for making the same, including a main body segment made from a sheet formed into a tube and including specially shaped interlocking edges forming a serpentine joint routed locations where threshing element mounts attach to the rotor. | 08-28-2008 |
20080234018 | Rotor for a threshing system of an agricultural combine and method of making the same - A rotor for a threshing system of an agricultural combine and method for making the same, including a body of simplified, three part press fit construction including an inlet segment, a main body segment having threshing elements therearound, and a bulkhead to be connected to a drive mechanism. The inlet segment, main body segment and bulkhead are configured so as to facilitate press fit assembly thereof concentric about a rotational axis about which the rotor will be rotated during operation, while also minimizing eccentricities of those components. As a result, the manufacture of the rotor is simplified by the elimination of the need for an internal skeleton structure and associated welds and/or fasteners. | 09-25-2008 |
Michael Epperly, Pittsburgh, PA US
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20110172214 | USE OF TARGETED NITROXIDE AGENTS IN PREVENTING, MITIGATING AND TREATING RADIATION INJURY - Provided herein are compositions and related methods useful for free radical scavenging, with particular selectivity for mitochondria. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cross-linked into dimers without loss of activity. Also provided herein are methods, for preventing, mitigating and treating damage caused by radiation. The method comprises delivering a compound, as described herein, to a patient in an amount and dosage regimen effective to prevent, mitigate or treat damage caused by radiation. | 07-14-2011 |
Michael Epperly, Mccandless, PA US
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20110288178 | RADIOPROTECTIVE AGENTS - Provided herein are methods, for reducing, preventing, mitigating and treating damage caused by radiation. The methods comprise delivering a compound, as described herein, to a patient in an amount and dosage regimen effective to prevent, mitigate or treat damage caused by radiation or to mitigate apoptosis. The compounds comprise glyburide or other sulfonylurea hypoglycemic compounds or potassium channel inhibitors. | 11-24-2011 |
Michael S. Epperly, Bear, DE US
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20090130435 | Intermetallic-containing composite bodies, and methods for making same - Composite bodies made by a silicon metal infiltration process that feature a silicon intermetallic, e.g., a metal silicide. Not only does this give the composite material engineer greater flexibility in designing or tailoring the physical properties of the resulting composite material, but the infiltrant also can be engineered compositionally to have much diminished amounts of expansion upon solidification, thereby enhancing net-shape-making capabilities. These and other consequences of engineering the metal component of composite bodies made by silicon infiltration permit the fabrication of large structures of complex shape. | 05-21-2009 |
20120277087 | INTERMETALLIC-CONTAINING COMPOSITE BODIES, AND METHODS FOR MAKING SAME - Composite bodies made by a silicon metal infiltration process that feature a silicon intermetallic, e.g., a metal silicide. Not only does this give the composite material engineer greater flexibility in designing or tailoring the physical properties of the resulting composite material, but the infiltrant also can be engineered compositionally to have much diminished amounts of expansion upon solidification, thereby enhancing net-shape-making capabilities. These and other consequences of engineering the metal component of composite bodies made by silicon infiltration permit the fabrication of large structures of complex shape. | 11-01-2012 |
Michael W. Epperly, Pittsburgh, PA US
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20120252733 | USE OF TARGETED NITROXIDE AGENTS IN BONE HEALING - Provided herein are compositions and related methods useful for accelerating bone healing and growth. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cross-linked into dimers without loss of activity. | 10-04-2012 |
20130203829 | Mitochondria-Targeted Inhibitors of Cytochrome C Peroxidase for Protection from Apoptosis - The present application is directed to novel imidazole-substituted fatty acids that have been functionalized with an alkyl triphenylphosphonium group, compositions comprising these compounds and their use as inhibitors of cytochrome c peroxidase, in particular for the treatment and prevention of apoptosis. | 08-08-2013 |
20140199368 | INTRAESOPHAGEAL ADMINISTRATION OF TARGETED NITROXIDE AGENTS FOR PROTECTION AGAINST IONIZING IRRADIATION-INDUCED ESOPHAGITIS - Provided herein are compositions and related methods useful for prevention or mitigation of ionizing radiation-induced esophagitis. The compositions comprise compounds comprising a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cross-linked into dimers without loss of activity. The method comprises delivering a compound, as described herein, to a patient in an amount and dosage regimen effective to prevent or mitigate esophageal damage caused by radiation. | 07-17-2014 |
20140256654 | BIFUNCTIONAL COMPOUNDS - A compound having the formula: | 09-11-2014 |
Michael Wayne Epperly, Pittsburgh, PA US
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20150306034 | FORMULATIONS AND CARRIER SYSTEMS INCLUDING COMPOUND INTERACTIVE DOMAINS - A method of creating a formulation for a compound includes determining a compound interactive agent comprising at least one group that interacts with the compound, creating a carrier agent by conjugating at least one compound interactive domain comprising the at least one group that interacts with the compound with at least one hydrophilic domain, and combining the compound and the carrier agent to create the formulation. Creating the carrier agent may further include conjugating the at least one compound interactive domain with at least one hydrophobic domain so that the at least one compound interactive domain is positioned between the at least one hydrophilic domain and the at least one hydrophobic domain. | 10-29-2015 |
Scott Epperly, Torrance, CA US
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20120059424 | Clavicle Bone Plate - A bone plate for treating clavicle fractures. The bone plate may include an elongated body having one or more curved portions that roughly conform to the surface and/or anatomical curvature of the clavicle. One or more openings may be provided for receiving an anchoring member, such as a bone screw, for fastening at least a portion of the bone plate onto the clavicle. The bone plate may provide at least one rail member extending along a portion of the body of the bone plate. The bone plate, when affixed to the clavicle, permits the rail member to rest upon the outer surface of the clavicle, thus providing an area defining a cavity formed between an outer surface of the clavicle and a bottom surface of the body of the bone plate, and thus allowing blood to circulate against and around the clavicle. | 03-08-2012 |
20120059428 | Telescoping Bone Screw - A bone screw for treating a bone fracture having a plunger assembly and a detent assembly on a body portion thereof. The detent assembly includes a detent member that is movable between a first and second position. The plunger assembly includes a threaded engagement portion and a plunger portion. The plunger portion is slidably disposed within a chamber of the body. The detent assembly operative to secure the body whereby said plunger portion moves independent of said body. | 03-08-2012 |
Scott Epperly, East Bridgewater, MA US
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20090035346 | Methods and Compositions for Enhancing Vascular Access - Disclosed is an implantable material comprising a biocompatible matrix and cells which, when provided to a vascular access structure, can promote functionality generally. For example, implantable material of the present invention can enhance maturation of an arteriovenous native fistula as well as prolong the fistula in a mature, functional state suitable for dialysis. Additionally, the present invention can promote formation of a functional arteriovenous graft suitable for dialysis as well as promote formation of a functional peripheral bypass graft. Implantable material can be configured as a flexible planar form or a flowable composition with shape-retaining properties suitable for implantation at, adjacent or in the vicinity of an anastomoses or arteriovenous graft. According to the methods disclosed herein, the implantable material is provided to an exterior surface of a blood vessel. Certain embodiments of the flexible planar form define a slot. The materials and methods of the present invention comprise cells, preferably endothelial cells or cells having an endothelial-like phenotype. | 02-05-2009 |
20100204783 | METHODS AND COMPOSITIONS FOR ENHANCING VASCULAR ACCESS - Disclosed is an implantable material comprising a biocompatible matrix and cells which, when provided to a vascular access structure, can promote functionality. | 08-12-2010 |
20100318016 | Methods and Compositions for Enhancing Vascular Access - Disclosed is an implantable material comprising a biocompatible matrix and cells which, when provided to a vascular access structure, can promote functionality generally. For example, implantable material of the present invention can enhance maturation of an arteriovenous native fistula as well as prolong the fistula in a mature, functional state suitable for dialysis. Additionally, the present invention can promote formation of a functional arteriovenous graft suitable for dialysis as well as promote formation of a functional peripheral bypass graft. Implantable material can be configured as a flexible planar form or a flowable composition with shape-retaining properties suitable for implantation at, adjacent or in the vicinity of an anastomoses or arteriovenous graft. According to the methods disclosed herein, the implantable material is provided to an exterior surface of a blood vessel. Certain embodiments of the flexible planar form define a slot. The materials and methods of the present invention comprise cells, preferably endothelial cells or cells having an endothelial-like phenotype. | 12-16-2010 |
20110229549 | Methods and Compositions for Enhancing Vascular Access - Disclosed is an implantable material comprising a biocompatible matrix and cells which, when provided to a vascular access structure, can promote functionality generally. For example, implantable material of the present invention can enhance maturation of an arteriovenous native fistula as well as prolong the fistula in a mature, functional state suitable for dialysis. Additionally, the present invention can promote formation of a functional arteriovenous graft suitable for dialysis as well as promote formation of a functional peripheral bypass graft. Implantable material can be configured as a flexible planar form or a flowable composition with shape retaining properties suitable for implantation at, adjacent or in the vicinity of an anastomoses or arteriovenous graft. According to the methods disclosed herein, the implantable material is provided to an exterior surface of a blood vessel. Certain embodiments of the flexible planar form define a slot. The materials and methods of the present invention comprises cells, preferably endothelial cells or cells having an endothelial-like phenotype. | 09-22-2011 |
Scott Epperly, Redondo Beach, CA US
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20130041414 | Telescoping Bone Screw - A bone screw for treating a bone fracture having a detent assembly on a body portion thereof. The detent assembly includes a detent member that is movable between a first and second position. The detent assembly operative to secure the body whereby said plunger portion moves independent of said body. The bone screw may also include a plunger assembly having a plunger with a threaded portion and a plunger portion. The plunger portion is slidably disposed within a chamber of the body. | 02-14-2013 |
20140336715 | Telescoping Bone Screw - A bone screw for treating a bone fracture having a detent assembly on a body portion thereof. The detent assembly includes a detent member that is movable between a first and second position. The detent assembly operative to secure the body whereby said plunger portion moves independent of said body. The bone screw may also include a plunger assembly having a plunger with a threaded portion and a plunger portion. The plunger portion is slidably disposed within a chamber of the body. | 11-13-2014 |