Eberts
Daniela Eberts, Finthen DE
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20150313978 | Novel MHC-Independent Tumor-Associated Antigens - The present invention relates to novel tumor-associated antigens, which elicit independently from a presentation via MHC a CD8-positive T-cell response. GM-CSF-Receptor alpha chain (CSF2RA) and Tyrosinase-related protein 2 (TRP-2) were found to be targets of CD8-positive T-cell clones which could detect the proteins on the surface of HLA I negative melanoma cells. Thus, the invention provides proteins, protein fragments and polypeptides of the novel antigens for use in medicine, for example for the treatment, diagnosis and prevention of a tumor disease. Furthermore provided are nucleic acids expressing the antigens of the invention, binding agents specific for the antigens of the invention, such as T-cell receptor chains and isolated T cells which are reactive against the antigens of the invention or which express the T-cell receptors of the invention. The invention further pertains to pharmaceutical compositions, especially vaccine compositions, comprising the antigens, nucleic acids, binding agents or T cells in accordance with the invention, and methods for the generation of T cells, which are specifically reactive to the antigens of the invention in an MHC-independent manner. | 11-05-2015 |
Daniela Eberts, Mainz DE
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20090104186 | Melanoma-associated MHC class I associated oligopeptides and the uses thereof - The present invention relates to certain melanoma-associated oligopeptides that are recognized by CD8-positive cytotoxic T-lymphocytes (CTLs) as peptide antigen and which elicit a CTL-induced lysis and/or apoptosis of tumor cells. The present invention also relates to the use of these melanoma-associated oligopeptides in cancer therapy. | 04-23-2009 |
Ken Eberts, Somerset, NJ US
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20120219804 | LAYERED BODY - A layered body ( | 08-30-2012 |
Kenneth C. Eberts, Westfield, NJ US
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20140141242 | TWO LAYER COATING FOR FIBERGLASS TRANSMISSION AND DISTRIBUTION COMPONENTS - A composite component having a two layer protective coating is disclosed. The composite component is adapted for use in the power transmission industry and includes a fiberglass inner core, a pliable first coating layer applied to the fiberglass core, and a hard second coating layer applied to the first coating layer. | 05-22-2014 |
Scott Eberts, Pella, IA US
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20090072062 | Apparatus and method for supporting a removable anvil - A grinding machine having a mounting arrangement and an anvil. The grinding machine generally including a feed table and a grinding drum positioned within a mill box. The mounting arrangement being configured to support an end of the feed table and the anvil. The anvil including a wedge-shaped portion and having a length. The length of the anvil being configured to extend beyond sides of the mill box. | 03-19-2009 |
20090242677 | Apparatus and method for supporting a removable anvil - A grinding machine having an improved anvil mounting arrangement is provided. The mounting arrangement according to the present disclosure is configured to securely support an end of the feed table and an anvil, and also enables easy replacement of the anvil. | 10-01-2009 |
William G. Eberts, Moon Township, PA US
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20140253264 | CIRCUIT BREAKER SLOT MOTOR - A two-piece slot motor housing assembly is provided. The slot motor housing assembly includes a first J-shaped body baying a lower, first end and a second, J-shaped body having a lower, first end. The first and second J-shaped bodies coupled to form a U-shaped assembly. The first J-shaped body first end overlaps the second J-shaped body first end. | 09-11-2014 |
20140374227 | SHUNT SEPARATING CAM FOLLOWERS FOR CIRCUIT BREAKERS AND RELATED METHODS - Circuit breakers with a cam follower having an upper post with the cam follower held by a cross bar to prevent cam/arm misalignment during high interruption shot on the breaker. Related cam followers have an upwardly extending post located on one side edge portion and cooperates with a shunt to provide shunt separation during high interruption breaker shots. | 12-25-2014 |
William George Eberts, Moon Township, PA US
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20140110230 | ATTACHMENT APPARATUS USABLE IN CIRCUIT INTERRUPTER ENVIRONMENT AND STRUCTURED TO CONNECT A RING TERMINAL TO THE CIRCUIT INTERRUPTER - An attachment apparatus is usable as a line terminal or load terminal of a circuit interrupter to enable a conductive element that includes a ring terminal to be electrically connected with a conductor of a circuit interrupter. The attachment apparatus employs a conventional lug which serves as a connector. The lug includes a threaded engagement element. The attachment apparatus further includes a connection element having a threaded receptacle that is structured to receive a shank of a threaded fastener. The shank is received through a hole formed in a ring terminal and is further threadably receivable in the receptacle of the connection apparatus to enable the ring terminal and a wire connected therewith to be reliably electrically connected with a line conductor or a load conductor of the circuit interrupter. The threaded shank can be unthreaded from the connection element to permit removal of the ring terminal and associated wire. | 04-24-2014 |