Patent application number | Description | Published |
20120034317 | Prediction of Response to Platinum-Based Therapy - Method for determining whether a mammalian subject having a cancer belongs to a first or a second group, wherein subjects of the first group are more likely to respond to a platinum-based therapy than subjects of the second group, comprising the steps of: evaluating the amount of RBM3 protein or RBM3 mRNA present in at least part of a sample earlier obtained from said subject, and determining a sample value corresponding to said amount; comparing the sample value with a reference value; and, if said sample value is higher than said reference value, concluding that said subject belongs to a first group; and if said sample value is lower than or equal to said reference value, concluding that said subject belongs to a second group. There is further provided means useful in the establishment of a treatment prediction. | 02-09-2012 |
20120040338 | RBM3 in Testicular Cancer Diagnostics and Prognostics - The present disclosure provides a method for determining whether a mammalian subject belongs to a first or a second group, wherein subjects of the first group have a higher risk of having a testicular disorder than subjects of the second group, comprising the steps of: evaluating an amount of RBM3 protein or RBM3 mRNA in at least part of an earlier obtained sample comprising biological material from a testicle of said subject and determining a sample value corresponding to the evaluated amount; comparing said sample value with a predetermined reference value; and if said sample value is higher than said reference value, concluding that the subject belongs to the first group; and if said sample value is lower than or equal to said reference value, concluding that the subject belongs to the second group. Further, a prognostic method for testicular cancer is provided, as well as means and uses with prognostic and diagnostic applications. | 02-16-2012 |
20140170676 | RBM3 in Bladder Cancer - The present disclosure relates, in one of its aspects, to a method for determining whether a mammalian subject having a bladder cancer belongs to a first or a second group, wherein the prognosis of subjects of the first group is better than the prognosis of subjects of the second group. The method comprises the steps of: a) evaluating an amount of RBM3 in at least part of a sample earlier obtained from the subject and determining a sample value corresponding to the evaluated amount; b) comparing said sample value with a predetermined reference value; and if said sample value is higher than said reference value, c1) concluding that the subject belongs to the first group; and if said sample value is lower than or equal to said reference value, c2) concluding that the subject belongs to the second group. | 06-19-2014 |
Patent application number | Description | Published |
20090135995 | Tomographic Mammography Method - A tomosynthesis system for forming a three dimensional image of an object is provided. The system includes an X-ray source adapted to irradiate the object with a beam of X-rays from a plurality of positions in a sector, an X-ray detector positioned relative to the X-ray source to detect X-rays transmitted through the object and a processor which is adapted to generate a three dimensional image of the object based on X-rays detected by the detector. The detector is adapted to move relative to the object and/or the X-ray source is adapted to irradiate the object with the beam of X-rays such that the beam of X-rays follows in a non arc shaped path and/or a center of the beam of X-rays impinges substantially on the same location on the detector from different X-ray source positions in the sector. | 05-28-2009 |
20110102430 | SYSTEM AND METHOD FOR PRESENTING TOMOSYNTHESIS IMAGES - A method and system for presenting images of an object of interest is provided. The method includes producing one or more cine loops of images from at least one of multiple projection views or multiple reconstructed 3D images including a 3D volume obtained from one or more beamlines. The method also includes generating at least one combined image including a first component and a second component wherein the first component and the second component each include one of a baseline image or the one or more cine loops of images. The combined image is generated via at least one of superimposing the first component and the second component, displaying the first component adjacent to the second component, and toggling between the first component and the second component. The method also includes displaying the at least one combined image. | 05-05-2011 |
20110142201 | MULTI-VIEW IMAGING SYSTEM AND METHOD - A multi-view imaging system and method is disclosed. The system comprises: multiple X-ray sources emitting X-rays in a fan-shaped beam each having a first and a second beam edge defining a fan beam angle located in a predetermined configuration around an imaging volume; a system controller configured to operate the X-ray sources; detectors, to detect X-rays and configured to generate signals in response to the detected X-rays, wherein each of the plurality of X-ray sources are configured to emit X-rays to one or more detectors, further wherein the X-ray source and two end points of a corresponding detector define a fan beam plane, further wherein a line extending from the X-ray source within the fan beam plane and through the imaging volume defines a projection direction, wherein adjacent projection directions define an angular spacing; an object conveyance device configured for transporting an object along a path of travel through the imaging volume between the X-ray sources and the detectors; and a detector interface configured to acquire the signals from the detectors, wherein the predetermined configuration is defined wherein either: the projection directions when viewed along a longitudinal axis of the image system surround the imaging volume by an angular range of about 180 degrees; or the projection directions when viewed along a longitudinal axis of the image system surround the imaging volume by an angular range of about 180°−180/Q, wherein Q is a quantity of the projection directions. | 06-16-2011 |
20110268245 | MULTIPLE BEAM LINE TOMOSYNTHESIS IMAGING - A method of imaging an object includes providing a stationary x-ray tube, that is configured to emit a cone beam of x-rays, wherein a line extending from the x-ray tube and through the object defines a tomographic angle and a beamline, further wherein the x-ray tube is configured to emits x-rays from several tomographic angles; providing a system controller configured to operate the x-ray tube; locating at least one flat-panel area detector opposite the x-ray tube, thereby defining a field of view, wherein flat-panel area detector(s) is configured to receive the emitted x-rays from the different tomographic angles, further wherein the detector(s) comprise an array of L×W detector elements; conveying the object along the path of travel; and selectively emitting x-rays from the x-ray tube in the tomographic angles through the object, wherein each beamline emitted from the x-ray tube impinges on a different portion of the flat-panel area detector. | 11-03-2011 |
20110306864 | POSITIONER FOR ULTRA-PORTABLE IMAGING SYSTEM - A flexible, lightweight, easily maneuverable positioner for an imaging system. The positioning system in one example has a cart section with a base frame coupled to one or more wheels. There is a mast extending from the cart section and a linkage assembly coupled to a second end of the mast, wherein the mast is configured to swing about a vertical plane. There is a positioning arm coupled to the linkage assembly, wherein the positioning arm is configured to swing about at least one of a horizontal plane and the vertical plane. An imaging bracket is used to couple to the positioning arm and configured to receive an imaging unit. In one example, the positioner is coupled together by fasteners, wherein the positioner can be assembled and dis-assembled via the fasteners without tools | 12-15-2011 |
20120020448 | SYSTEM AND METHOD FOR RECONSTRUCTION OF X-RAY IMAGES - Systems and method for reconstruction of x-ray images are provided. One method includes acquiring a plurality of image views using an x-ray imaging system, the plurality of image views defining a limited tomographic dataset. The method also includes performing three-dimensional (3D) image reconstruction using the plurality of image views in an iterative reconstruction, wherein the iterative reconstruction includes forming a linear combination based on a plurality of previous iteration results. The method further includes displaying an image based on the image reconstruction, wherein the image includes clinically relevant high-frequency detail information. | 01-26-2012 |
20120275563 | SYSTEM AND METHOD FOR ORIENTING AN X-RAY DETECTOR - The subject matter disclosed herein relates to X-ray imaging systems, and more specifically to digital X-ray imaging systems. In one embodiment, an imaging system includes an X-ray source configured to emit X-rays. The imaging system also includes an X-ray detector configured to detect the emitted X-rays and produce a corresponding electrical signal. The imaging system also includes a gantry configured to at least partially revolve the X-ray source and the X-ray detector about a primary rotational axis. The X-ray detector is coupled to the gantry so that a diagonal of the X-ray detector is oriented substantially perpendicular to the primary rotational axis. | 11-01-2012 |
20130170615 | RADIATION DETECTOR FOR USE IN SEQUENTIAL IMAGE ACQUISITION - A radiation detector is provided that provides fast sequential image acquisition. In one embodiment, the radiation detector a diode capacitor that is charged in response to a radiation exposure event. The charge stored in the diode capacitor is transferred to a separate storage capacitor, allowing a new charge to be generated and stored at the diode capacitor. | 07-04-2013 |
20130322602 | INTERNAL SHIELDING X-RAY TUBE - An x-ray tube is presented. One embodiment of the x-ray tube includes a cathode unit configured to emit electrons. The x-ray tube further includes an anode unit positioned to receive the emitted electrons, wherein the anode unit includes a base having a target surface configured to generate x-rays when the emitted electrons impinge on the target surface. Also, the anode unit includes a first shielding unit enclosing the base to attenuate at least a first portion of the generated x-rays within the anode unit. | 12-05-2013 |
20140064456 | MOTION CORRECTION SYSTEM AND METHOD FOR AN X-RAY TUBE - A motion correction system and method for motion correction for an x-ray tube is presented. One embodiment of the motion correction system includes a sensing unit coupled to an x-ray tube to determine a distance with which an impingement location of an electron beam generated by the x-ray tube deviates from a determined location due to motion of the x-ray tube. The motion correction system further includes a control unit coupled to the sensing unit to generate a control signal corresponding to the distance with which the impingement location of the electron beam deviates. Also, the motion correction system includes a deflection unit coupled to the control unit to steer the electron beam to the determined location based on the generated control signal. | 03-06-2014 |
20140112437 | SYSTEM AND METHOD FOR CONTROLLING A PORTABLE X-RAY SYSTEM - The subject matter disclosed herein relates to patient imaging systems, and more specifically, to portable X-ray imaging systems. In a first embodiment, a patient imaging system is presented. The patient imaging system includes an X-ray source configured to emit X-rays and a wireless X-ray detector configured to detect the emitted X-rays and acquire patient image data. The patient imaging system also includes an acquisition control system configured to initialize and prepare the patient imaging system for X-ray emission and detection. The acquisition control system is also configured to receive the acquired patient image data from the X-ray detector, and to non-deterministically control the operation of the X-ray source and the wireless X-ray detector. The patient imaging system also includes one or more user interfaces configured to instruct the acquisition control system when a user is ready for the patient imaging system to initialize, to prepare for X-ray emission and detection, and to begin X-ray emission and detection. | 04-24-2014 |
20140112449 | SYSTEM AND METHOD FOR COLLIMATING X-RAYS IN AN X-RAY TUBE - An apparatus and method for providing a predefined x-ray field is presented. Briefly in accordance with one aspect of the present disclosure, the apparatus includes a cathode unit configured to emit electrons within a vacuum chamber. The apparatus further includes an anode unit configured to generate x-rays when the emitted electrons impinge on a target surface of the anode unit. Also, the apparatus includes a collimating unit comprising a primary set of blades disposed in the vacuum chamber at a first distance from the anode unit for collimating the generated x-rays to provide the predefined x-ray field at a detector. | 04-24-2014 |
20140153690 | SYSTEMS AND METHODS FOR IMAGING DYNAMIC PROCESSES - Systems, methods and non-transitory computer readable media for imaging. The system includes one or more radiation sources and detectors configured to transmit x-ray radiation towards a subject for imaging a dynamic process in a ROI of the subject and to acquire projection data corresponding to the ROI, respectively. The system also includes a computing device operatively coupled to one or more of the radiation sources and the detectors. The computing device is configured to provide control signals for performing one or more reference scans for acquiring reference data from a plurality of angular positions around the subject and for performing one or more tomosynthesis scans using one or more tomosynthesis trajectories for acquiring tomosynthesis data following the onset of the dynamic process. Additionally, the computing device is configured to reconstruct one or more images representative of the dynamic process using the reference data and/or the tomosynthesis data. | 06-05-2014 |
20150095397 | INTEGRATED SYSTEMS FOR USE IN INTERVENTIONAL PROCEDURES - The present disclosure relates to the use of integrated or consolidated systems for use in interventional systems. By way of example, in a procedure room a single console or platform may be provided (as opposed to multiple stand-alone platforms) having interventional tools (such as imaging, monitoring, or navigational tools) for use with a patient in the procedure room. Other components of the systems may be provided at different locations, such as in a technical or control room, depending on their function and/or whether the components need to be in a particular location, such as proximate to the patient or to a user. | 04-02-2015 |
20150238159 | SYSTEM AND METHOD FOR PERFORMING BI-PLANE TOMOGRAPHIC ACQUISITIONS - A method includes, in a bi-plane interventional imaging system, moving a first C-arm supporting a first X-ray source and a first X-ray detector about first and second axes while obtaining a plurality of first X-ray attenuation data sets relating to a subject of interest; moving a second C-arm, positioned crosswise with respect to the first C-arm and supporting a second X-ray source and a second X-ray detector, about the first axis while obtaining a plurality of second X-ray attenuation data sets relating to the subject of interest; and synchronizing the movement of the first and second C-arms to avoid collision therebetween. | 08-27-2015 |