Patent application number | Description | Published |
20090258828 | INVESTIGATION OF MUCOSA DRYNESS CONDITIONS - The present invention relates to diagnosis and/or treatment of medical conditions. The present invention relates to new method of diagnosing dry mucosa condition in a subject. The condition may be dry eye. The present invention also provides a method to monitor the efficacy of a treatment of a dry mucosa condition, a method of treating a dry mucosa condition and/or a diagnostic kit for a dry mucosa condition. | 10-15-2009 |
20100048469 | ANTIMICROBIAL PEPTIDES - There is provided at least one isolated antimicrobial peptide, wherein the peptide is a linear analog of hBD3 or a fragment thereof. In particular, there is provided a linear analog of hBD3 wherein the peptide has a reduced cytotoxicity to at least one cell compared to the wild type hBD3. | 02-25-2010 |
20100211051 | System and method for descemet's stripping automated endothelial keratoplasty (DSAEK) surgery - The system for donor cornea implantation includes a preparation base having a well for receiving a posterior lamellar donor corneal lenticule, a cartridge disengageably mounted on the base adjacent the well, and a handle for disengageable attachment to a posterior end portion of the cartridge. In drawing the donor lenticule from the well into and through a bore or chamber of the cartridge, from the posterior end, the lenticule is caused to assume a double coil configuration. After attachment of the handle, removal of the assembly from the preparation base, and insertion of blade and adjacent body portions of the cartridge through an incision in the cornea, the coiled donor lenticule is pulled from the cartridge bore through its forward end, to uncoil automatically within the anterior chamber of the recipient's eye. | 08-19-2010 |
20110039760 | MULTIMERIC FORMS OF ANTIMICROBIAL PEPTIDES - The invention relates to multimeric forms of antimicrobial peptides, for example, defensin peptides. The multimeric forms of defensin peptides possesses antimicrobial activity and may be formulated into antimicrobial compositions, pharmaceutical compositions, eyedrop composition, contact lens solution compositions for coating medical devices and the like. The invention also relates to the use of these multimeric forms of peptides, e.g. multimeric forms of defensin peptides for inhibiting and/or reducing the growth of microorganisms in general, including in a host. The invention further relates to a method of preparing multimers of peptides derived from defensins, for example hBD3. | 02-17-2011 |
20120226286 | System and method for preparing a lenticular or corneal implant - A system for use in preparing a lenticular or corneal implant includes a cartridge having a generally tubular portion, comprised of a sidewall defining a longitudinal bore of curvilinear cross section and having open forward and rearward ends. The system also includes a preparation base with an upper portion having a recess and cartridge-receiving structure for removably engaging the cartridge in position with the open, rearward end of the longitudinal bore thereof proximate one side of the recess, allowing for facile removal of the cartridge from the base. An insert member has structure for removably engaging it in the recess, and has one portion defining a platform for receiving the implant and another, adjacent portion defining funnel structure having a wider end facing the platform and a narrower end facing the open rearward end of the cartridge. | 09-06-2012 |
20130085567 | Method and apparatus for performing DMEK surgery - DMEK surgery is performed using a carrier mat made of a polymeric material having elastic memory and a hydrophilic surface, for supporting the descemet's membrane and transporting it to an insertion capsule. | 04-04-2013 |
20140142027 | MULTIMERIC FORMS OF ANTIMICROBIAL PEPTIDES - The invention relates to multimeric forms of antimicrobial peptides, for example, defensin peptides. The multimeric forms of defensin peptides possesses antimicrobial activity and may be formulated into antimicrobial compositions, pharmaceutical compositions, eyedrop composition, contact lens solution compositions for coating medical devices and the like. The invention also relates to the use of these multimeric forms of peptides, e.g. multimeric forms of defensin peptides for inhibiting and/or reducing the growth of microorganisms in general, including in a host. The invention further relates to a method of preparing multimers of peptides derived from defensins, for example hBD3. The method includes a composition or combination comprising the multimeric antimicrobial peptides and at least one active pharmaceutical ingredient. | 05-22-2014 |
20150203815 | CELL CULTURE OF CORNEAL ENDOTHELIAL CELLS - The invention relates to a dual-media approach for culturing isolated corneal endothelial cells. Isolated corneal endothelial cells are first contacted with a proliferative medium to propagate and/or expand the endothelial cells followed by a maintenance medium to preserve the morphology and/or characteristics of the corneal endothelial cells. The invention includes the proliferative medium and the maintenance medium and also a combination of the two medium. | 07-23-2015 |