Patent application number | Description | Published |
20140113302 | METHODS FOR SEQUENCING, AMPLIFICATION AND DETECTION OF NUCLEIC ACIDS COMPRISING INTERNALLY LABELLED PRIMER - The present application provides for an enhanced method for sequencing, or amplifying and detecting nucleic acids comprising the steps of: i) providing at least one nucleic acid primer comprising at least one labelled nucleotide, ii) providing enzymes and reagents for amplification of a target nucleic acid using said at least one labelled nucleic acid primer, iii) incubating the components of the reaction under conditions suited for amplification of the target nucleic acid primer, iv) detecting the amplified nucleic acids via the labelled nucleotide, wherein the nucleic acid primer comprises the following sequence: 5′-N | 04-24-2014 |
20140178878 | OLIGONUCLEOTIDS COMPRISING A LABEL ASSOCIATED THROUGH A LINKER - The present application discloses a labeled nucleotide comprising a label attached via a linker, wherein said labeled nucleotide has the formula wherein R | 06-26-2014 |
20140234834 | METHOD FOR QUANTIFYING HUMAN DNA - The invention provides for a method for quantifying one or more nucleic acids of a genome in a sample comprising the steps of (a) amplifying a first nucleic acid to be quantified, (b) determining the amount of said first nucleic acid by comparison of the amount of amplification product from said first nucleic acid with at least one amplification product from a second template nucleic acid, (c) wherein said second template nucleic acid was generated using whole genome amplification and wherein the starting concentration of the second template nucleic acid is known. | 08-21-2014 |
Patent application number | Description | Published |
20120253018 | Bovine Adeno-Associated Viral (BAAV) Vector and Uses Thereof - The present invention provides a bovine adeno-associated virus (BAAV) virus and vectors and particles derived therefrom. In addition, the present invention provides methods of delivering a nucleic acid to a cell using the BAAV vectors and particles. | 10-04-2012 |
20140088175 | TRANSDUCTION OF CELLS BY ADENO-ASSOCIATED VIRUS VECTORS - The present invention provides methods of transcytosing barrier epithelial cells using adeno-associated virus-4 (AAV4), adeno-associated virus-5 (AAV5), adeno-associated virus-7 (AAV7), bovine adeno-associated virus (BAAV), and vectors and particles derived therefrom. In addition, the present invention provides methods of delivering a nucleic acid across the barrier epithelia using the AAV4, AAV5, AAV7, and BAAV vectors and particles. | 03-27-2014 |
20140199272 | AAV MEDIATED EXENDIN-4 GENE TRANSFER TO SALIVARY GLANDS TO PROTECT SUBJECTS FROM DIABETES OR OBESITY - The invention relates to a gene transfer-based method to protect a subject from diabetes or obesity. The method comprises administering to a salivary gland of the subject an AAV virion comprising an AAV vector that encodes an exendin-4 protein. Also provided are exendin-4 proteins and nucleic acid molecules that encode such exendin-4 proteins. Also provided are AAV vectors and AAV virions that encode an exendin-4 protein. One embodiment is an exendin-4 protein that is a fusion protein comprising an NGF secretory segment joined to the amino terminus of an exendin-4 protein domain. | 07-17-2014 |
20140221636 | Bovine Adeno-Associated Viral (BAAV) Vector and Uses Thereof - The present invention provides a bovine adeno-associated virus (BAAV) virus and vectors and particles derived therefrom. In addition, the present invention provides methods of delivering a nucleic acid to a cell using the BAAV vectors and particles. | 08-07-2014 |