Patent application number | Description | Published |
20090118502 | BIARYL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME - The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of compounds having both a biaryl moiety and at least one heterocylic moiety that are useful as such agents. | 05-07-2009 |
20100234591 | BIARYL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME - The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of compounds having both a biaryl moiety and at least one heterocylic moiety that are useful as such agents. | 09-16-2010 |
20120010200 | Biaryl Heterocyclic Compounds And Methods Of Making And Using The Same - The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of compounds having both a biaryl moiety and at least one heterocylic moiety that are useful as such agents. | 01-12-2012 |
20120157442 | HETEROARYL BTK INHIBITORS - The present invention provides compounds useful as inhibitors of Btk, compositions thereof, and methods of using the same. | 06-21-2012 |
20120157443 | BRUTON'S TYROSINE KINASE INHIBITORS - The present invention provides compounds useful as inhibitors of Btk, compositions thereof, and methods of using the same. | 06-21-2012 |
20120208819 | HETEROCYCLIC COMPOUNDS USEFUL AS PDK1 INHIBITORS - The present invention provides compounds useful as inhibitors of PDK1. The present invention also provides compositions thereof, and methods of treating PDK1-mediated diseases. | 08-16-2012 |
20120252747 | MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME - The present invention provides macrocyclic compounds useful as therapeutic agents of the formula: | 10-04-2012 |
20130017997 | Factor VIII Compositions and Methods of Making and Using Same - The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions. | 01-17-2013 |
20130345192 | HETEROCYCLIC TYROSINE KINASE INHIBITORS - The present invention provides compounds useful as inhibitors of Tec family kinases, compositions thereof, and methods of using the same. | 12-26-2013 |
20140309212 | BRUTON'S TYROSINE KINASE INHIBITORS - The present invention provides compounds useful as inhibitors of Btk, compositions thereof, and methods of using the same. | 10-16-2014 |
20150038421 | FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME - The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions. | 02-05-2015 |
20150050271 | JCV NEUTRALIZING ANTIBODIES - In one aspect, the disclosure provides neutralizing antibodies against JCV and methods for the treatment of PML. In some embodiments, aspects of the invention relate to an isolated JC-vims neutralizing monoclonal antibody against JCV capsid protein VPI (JCV-VP1). In some embodiments, the antibody suppresses infectivity of the JC-vims. In some embodiments, the antibody binds the sialic acid binding pocket of JCV-VP1. | 02-19-2015 |
20150158901 | MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME - The present invention provides macrocyclic compounds useful as therapeutic agents of the formula: | 06-11-2015 |
20150158929 | FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME - The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions. | 06-11-2015 |
Patent application number | Description | Published |
20140073624 | Biaryl Heterocyclic Compounds and Methods of Making and Using the Same - The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of compounds having both a biaryl moiety and at least one heterocylic moiety that are useful as such agents. | 03-13-2014 |
20150072970 | BIARYL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME - The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of compounds having both a biaryl moiety and at least one heterocylic moiety that are useful as such agents. | 03-12-2015 |
20150210647 | ATX MODULATING AGENTS - Disclosed are bicyclic aryl compounds of formula (I), that can modulate the activity of the autotaxin (ATX) enzyme. This invention further relates to compounds that are ATX inhibitors, and methods of making and using such compounds in the treatment of demyelination due to injury or disease, as well as for treating proliferative disorders such as cancer. | 07-30-2015 |
Patent application number | Description | Published |
20090253431 | METHOD, SYSTEM AND DEVICE FOR REALIZING USER IDENTITY ASSOCIATION - The present invention discloses a method for realizing user identity association, the method comprising: setting an equivalent behavior user identifier in a Home Subscription Server (HSS); associating IMS Public User Identities (IMPUs) with the equivalent behavior through the set equivalent behavior user identifier. The present invention also discloses a system and a device realizing user identity association. According to the embodiments of the present invention, the association of the IMPUs with the set equivalent behavior is realized, which improves the user experiences. | 10-08-2009 |
20110038319 | Method, System and Device for Realizing User Identity Association - The present invention discloses a method for realizing user identity association, the method comprising: setting an equivalent behavior user identifier in a Home Subscription Server (HSS); associating IMS Public User Identities (IMPUs) with the equivalent behavior through the set equivalent behavior user identifier. The present invention also discloses a system and a device realizing user identity association. According to the embodiments of the present invention, the association of the IMPUs with the set equivalent behavior is realized, which improves the user experiences. | 02-17-2011 |
20130097402 | DATA PREFETCHING METHOD FOR DISTRIBUTED HASH TABLE DHT STORAGE SYSTEM, NODE, AND SYSTEM - Embodiments of the present disclosure provide a data prefetching method, a node, and a system. The method includes: a first storage node receives a read request sent by a client, determines a to-be-prefetched data block and a second storage node where the to-be-prefetched data block resides according to a read data block and a set to-be-prefetched data block threshold, and sends a prefetching request to the second storage node, the prefetching request includes identification information of the to-be-prefetched data block, and the identification information is used to identify the to-be-prefetched data block; and the second storage node reads the to-be-prefetched data block from a disk according to the prefetching request, and stores the to-be-prefetched data block in a local buffer, so that the client reads the to-be-prefetched data block from the local buffer of the second storage node. | 04-18-2013 |
20130111187 | DATA READ AND WRITE METHOD AND APPARATUS, AND STORAGE SYSTEM | 05-02-2013 |