Patent application number | Description | Published |
20100291706 | DYE CONJUGATES AND METHODS OF USE - The present invention relates to cyanine compounds, compositions comprising them, articles of manufacture, and methods of making and using them. The cyanines usefully comprise one or more carboxyl groups or derivatives thereof that are indirectly attached to an aryl ring on an alkylaryl cyanine substituent. Also provided are conjugates of the disclosed cyanines and one or more other substances. Solvates, solutions, and derivatized forms of the cyanines are also provided. The cyanines find use in a variety of bioassays, both in direct single-label applications and in energy transfer formats. Methods utilizing the disclosed cyanines for analyzing a sample for a target are provided. Also disclosed are detection complexes comprising the disclosed cyanines, as well as compositions and articles comprising the cyanines in an excited state, for example formed by direct excitation or by energy transfer. The cyanines may be used as alternatives to other known optically active species in a variety of settings. Other embodiments are described further herein. | 11-18-2010 |
20120088262 | CYANINE COMPOUNDS, CONJUGATES AND METHOD OF USE - Cyanine compounds having the general formula I, conjugates, complexes, and compositions comprising the cyanine compounds are provided. Fluorescence resonance energy transfer (FRET) dye pairs and viability dyes are also provided. | 04-12-2012 |
Patent application number | Description | Published |
20100247655 | Synthesis of Small Particles - The invention provides an apparatus for forming fine particles of a substance in a precipitation chamber, in which the apparatus has means to convey the fine particles from the precipitation chamber to at least one particle collection chamber, downstream of the precipitation chamber, the particle collection chamber having an inlet and an outlet separate from the inlet. The invention also provides a method of forming fine particles of a substance, the method comprising contacting a non-gaseous fluid containing the substance with a dense fluid to expand the non-gaseous fluid in a precipitation chamber, conveying a resulting mixture of fluid and the fine particles from the precipitation chamber to a collection chamber, the collection chamber having an inlet and an outlet separate from the inlet. | 09-30-2010 |
20120090604 | SYNTHESIS OF SMALL PARTICLES - The invention provides an apparatus for forming fine particles of a substance in a precipitation chamber, in which the apparatus has means to convey the fine particles from the precipitation chamber to at least one particle collection chamber, downstream of the precipitation chamber, the particle collection chamber having an inlet and an outlet separate from the inlet. The invention also provides a method of forming fine particles of a substance, the method comprising contacting a non-gaseous fluid containing the substance with a dense fluid to expand the non-gaseous fluid in a precipitation chamber, conveying a resulting mixture of fluid and the fine particles from the precipitation chamber to a collection chamber, the collection chamber having an inlet and an outlet separate from the inlet. | 04-19-2012 |
20140086994 | Synthesis of Small Particles - The invention provides an apparatus for forming fine particles of a substance in a precipitation chamber, in which the apparatus has means to convey the fine particles from the precipitation chamber to at least one particle collection chamber, downstream of the precipitation chamber, the particle collection chamber having an inlet and an outlet separate from the inlet. The invention also provides a method of forming fine particles of a substance, the method comprising contacting a non-gaseous fluid containing the substance with a dense fluid to expand the non-gaseous fluid in a precipitation chamber, conveying a resulting mixture of fluid and the fine particles from the precipitation chamber to a collection chamber, the collection chamber having an inlet and an outlet separate from the inlet. | 03-27-2014 |
Patent application number | Description | Published |
20090152342 | Method Of Performing An Action In Relation To A Software Object - A method of performing an action is disclosed. The method starts by receiving, from a sensor, indicating data. The indicating data is indicative of a position of the sensor relative to a surface, and an identity of the surface. The indicating data is generated from sensing coded data on the surface. The coded data is indicative of a plurality of locations on the surface and the identity of the surface. Next the method identifies, using the indicating data, the identity of the surface and the position of the sensor relative to a surface. A request to perform the action is then determined. The request is associated with the identity and position. Next, using the request, action data indicative of the action is identified and, using the action data, the action is performed. | 06-18-2009 |
20100301112 | SYSTEM FOR PROVIDING INFORMATION TO USER WITH EVERY INTERACTION WITH PRINTED SUBSTRATE - A system for providing information to a user via a printed substrate. The substrate comprises user information and coded data. The coded data is indicative of a region identity associated with the substrate and of a plurality of locations on the substrate. The system includes an optically imaging sensing device for sensing the coded data and generating interaction data. Receipt of the interaction data by a computer system causes the computer system to identify and retrieve a page description corresponding to the printed substrate; determine whether the sensing device is positioned within a zone of a hyperlink on the substrate; and (i) if the sensing device is positioned within the zone of the hyperlink: send a hyperlink URI or a hyperlinked resource corresponding to the hyperlink to the user; or (ii) if the sensing device is positioned outside the zone of the hyperlink: generate a query expression, form a request and send search results to the user. | 12-02-2010 |
20110226851 | METHOD OF INTERACTING WITH SUBSTRATE IN CURSOR AND HYPERLINKING MODES - A method of interacting with a substrate and communicating with a computer system using a sensing device operable in a plurality of modes including a cursor control mode and a hyperlinking mode. The method includes the steps of: actuating a nib switch of the sensing device when a nib force exceeds a predetermined threshold; optically imaging coded data printed on the substrate; generating cursor control data when the sensing device is in said cursor control mode; generating interaction data using the imaged coded data when the sensing device is in the hyperlinking mode; and communicating the cursor control data or the interaction data to a computer system. The cursor control data initiates a cursor control response in the computer system while the interaction data initiates a hyperlinking response in the computer system. | 09-22-2011 |
20110302197 | SYSTEM FOR PROVIDING INFORMATION VIA CONTEXT SEARCHING OF PRINTED SUBSTRATE - A method of providing information to a user via a printed substrate, said substrate comprising user information and coded data indicative of a region identity associated with the substrate and of a plurality of locations on the substrate, said method comprising the steps of: receiving, in a computer system, interaction data indicative of the region identity and at least one position of a sensing device relative to the substrate, the sensing device generating the interaction data, when operatively positioned or moved relative to the substrate, by reading at least some of the coded data; identifying and retrieving at least part of a page description corresponding to the printed substrate using the region identity; generating a query expression comprising one or more search terms, at least one of said search terms being identified using the page description and the at least one position of the sensing device; forming a request using the query expression; and sending the request, or a results resource including search results obtained using the request, to the user. | 12-08-2011 |
20110309139 | SYSTEM FOR PROVIDING INFORMATION VIA INTERACTIVE SURFACE - A system for providing information via an interactive surface is provided. The surface has information for searching and coded data. The coded data encodes coordinates on the surface and a region identity associated with the surface. A sensing device interacted with the surface senses the coded data and generates interaction data indicative of the region identity and a coordinate position of the sensing device relative to the surface. The system identifies and retrieves a page description corresponding to the surface using the region identity received from the sensing device, determines the information for searching corresponding to a zone of the page description containing the coordinate position of the sensing device, creates a query expression having a search term(s) based on the determined information for searching, form a request using the query expression, and sends the request, or a results resource including search results from the request, to a display device. | 12-22-2011 |
20130176221 | SENSING DEVICE HAVING CURSOR AND HYPERLINKING MODES - An optical sensing device for controlling a computer system is disclosed. The device has a nib for receiving a nib force upon the nib being pressed against a substrate and a nib switch coupled to the nib. An optical sensor images optically coded data printed on the substrate. A processor effects a mode change between a cursor control mode and a hyperlinking mode upon the nib force actuating the nib switch, generates cursor control data when the optical sensing device is in the cursor control mode, and generates interaction data when the optical sensing device is in the hyperlinking mode. The interaction data indicates a coordinate position of the optical sensing device relative to the substrate. The cursor control data or the interaction data is then communicated to the computer system, where the cursor control data initiates a cursor control response and the interaction data initiates a hyperlinking response. | 07-11-2013 |
20130176441 | User interface system employing printed substrate and substrate sensing device - A user interface system includes a substrate having printed thereon user information and coded data, the coded data identifying various spatial regions of the printed substrate, and identifying a position of each coded data on the printed substrate; an optically imaging device configured to interact with the coded data on the substrate, generate interaction data indicating the physical region in which the device is interacting with the substrate; and a first computer system for receiving the interaction data, the first computer system configured to retrieve a digital version of the substrate, identify a digital region in the digital version corresponding to the physical region indicated by the interaction data, generate a query expression comprising of a search term identified from the digital region, and form a request from the query expression. | 07-11-2013 |