Patent application number | Description | Published |
20120191358 | RISK CALCULATION FOR EVALUATION OF FETAL ANEUPLOIDY - The present invention provides processes for determining accurate risk probabilities for fetal aneuploidies. Specifically, the invention provides non-invasive evaluation of genomic variations through chromosome-selective sequencing and non-host fraction data analysis of maternal samples. | 07-26-2012 |
20120191367 | ASSAY SYSTEMS FOR DETERMINATION OF FETAL COPY NUMBER VARIATION - The present invention provides processes for determining accurate risk probabilities for chromosome dosage abnormalities. Specifically, the invention provides non-invasive evaluation of genomic variations through chromosome-selective sequencing and non-host fraction data analysis of maternal samples. | 07-26-2012 |
20130024127 | DETERMINATION OF SOURCE CONTRIBUTIONS USING BINOMIAL PROBABILITY CALCULATIONS - This invention relates to calculation of percent contribution of data from a major source and a minor source in a sample. | 01-24-2013 |
20130060483 | DETERMINATION OF COPY NUMBER VARIATIONS USING BINOMIAL PROBABILITY CALCULATIONS - This invention relates to a binomial calculation of copy number of data obtained from a mixed sample having a first source and a second source. | 03-07-2013 |
20130089863 | RISK CALCULATION FOR EVALUATION OF FETAL ANEUPLOIDY - The present invention provides processes for determining accurate risk probabilities for fetal aneuploidies. Specifically, the invention provides non-invasive evaluation of genomic variations through chromosome-selective sequencing and non-host fraction data analysis of maternal samples. | 04-11-2013 |
20130178371 | NONINVASIVE DETECTION OF FETAL ANEUPLOIDY IN EGG DONOR PREGNANCIES - The present invention provides assay systems and methods for determining the percent fetal contribution of cell-free DNA in a maternal sample from a pregnant female with an egg donor pregnancy. Further provided, are assay systems and methods for determining a statistical likelihood of the presence or absence of a fetal aneuploidy in a maternal sample using a determined percent fetal cell-free DNA in the sample. | 07-11-2013 |
20130310262 | NONINVASIVE DETECTION OF ROBERTSONIAN TRANSLOCATIONS - The present invention provides methods for detection of Robertsonian translocations. | 11-21-2013 |
20130311107 | PROCESSES FOR CALCULATING PHASED FETAL GENOMIC SEQUENCES - The present invention provides processes for calculating phased genomic sequences of the fetal genome using fetal DNA obtained from a maternal sample. The processes and systems of the present invention utilize novel technological and computational approaches to detect fetal genomic sequences and determine the phased heritable genomic sequences. The invention could be used, e.g., to identify in utero deleterious mutations carried by the parents and inherited by a fetus within a particular heritable genomic region. | 11-21-2013 |
20140095136 | MATHEMATICAL NORMALIZATION OF SEQUENCE DATA SETS - The invention provides processes of the present invention provide normalization procedures for sequences within multiplexed data sets using the sequence information from multiplexed sequencing data set itself rather than the utilization of any external references. | 04-03-2014 |
20140180602 | DETERMINATION OF COPY NUMBER VARIATIONS USING BINOMIAL PROBABILITY CALCULATIONS - This invention relates to a binomial calculation of copy number of data obtained from a mixed sample having a first source and a second source. | 06-26-2014 |
20140188401 | DETERMINATION OF COPY NUMBER VARIATIONS USING BINOMIAL PROBABILITY CALCULATIONS - This invention relates to a binomial calculation of copy number of data obtained from a mixed sample having a first source and a second source. | 07-03-2014 |