Patent application number | Description | Published |
20080223578 | Polyelectrolyte Complexes as Delayed Gelling Agents for Oil and Gas Applications - A polyelectrolyte complex for the controlled or delayed gelation of a water and hydrocarbon producing subterranean formation. | 09-18-2008 |
20090098183 | MICROSPHERE-BASED MATERIALS WITH PREDEFINED 3D SPATIAL AND TEMPORAL CONTROL OF BIOMATERIALS, POROSITY AND/OR BIOACTIVE SIGNALS - A tissue engineering scaffold for growing cells can include a plurality of biocompatible microspheres linked together to form a three-dimensional matrix. The matrix can include a plurality of pores for growing cells. The biocompatible microspheres can include first and second sets of microspheres. The first set of microspheres can have a first characteristic, and a first predetermined spatial distribution with respect to the three-dimensional matrix. The second set of microspheres can have a second characteristic that is different from the first characteristic, and a second predetermined spatial distribution that is different from the first predetermined spatial distribution with respect to the three-dimensional matrix. The first and second characteristics can selected a composition, polymer, particle size, particle size distribution, type of bioactive agent, type of bioactive agent combination, bioactive agent concentration, amount of bioactive agent, rate of bioactive agent release, mechanical strength, flexibility, rigidity, color, radiotranslucency, radiopaqueness, or the like. | 04-16-2009 |
20090123509 | Biodegradable Colloidal Gels as Moldable Tissue Engineering Scaffolds - A colloid gel can include a plurality of positive charged particles mixed and associated with a plurality of negative charged particles so as to form a three-dimensional matrix having a plurality of pores defined by and disposed between the particles. The three-dimensional matrix can have shear thinning under shear and structure stability in the absence of shear. A method of manufacturing the colloid gel can include combining the positive charged particles with the negative charged particles, in a mold or in situ, so as to form the three-dimensional matrix having the plurality of pores. | 05-14-2009 |
20100056399 | Polyelectrolyte Complexes For Oil And Gas Applications - A polyelectrolyte complex for the controlled release of an oil and gas field chemical selected from the group consisting of (a) a gel-forming or cross-linking agent, (b) a scale inhibitor, (c) a corrosion inhibitor, (d) an inhibitor of asphaltene or wax deposition, (e) a hydrogen sulfide scavenger, (f) a hydrate inhibitor, (g) a breaking agent, and a surfactant. | 03-04-2010 |
20100233239 | Templated islet cells and small islet cell clusters for diabetes treatment - A scaffold having islet cells or small islet cell clusters attached thereto in a multilayer, and a micro-mold having divots for culturing islets, wherein islet formation is influenced by the shape and dimensions of the divots are disclosed. | 09-16-2010 |
20100292109 | SWELLABLE POLYMERS WITH HYDROPHOBIC GROUPS - The invention is directed to crosslinked water-soluble swellable polymers, methods for making same and their various uses. More particularly, the invention relates to a composition comprising expandable polymeric particles being made with 0.1-5% hydrophobic monomers and labile crosslinkers and stable crosslinkers, said particles mixed with a fluid. A particularly important use is as an injection fluid in petroleum production, where the expandable polymeric particles are injected into a well and when the heat and/or pH of the target zones in the formation cause degradation of the labile crosslinker and when the particle expands, the hydrophobic groups associate to form a hydrophobically associative polymer, thus diverting water to lower permeability regions and improving oil recovery. | 11-18-2010 |
20100314114 | SWELLABLE POLYMER WITH ANIONIC SITES - The invention is directed to stable crosslinked water-soluble swellable polymers and methods for making same. More particularly, the invention relates to a composition comprising expandable polymeric particles having anionic sites and labile crosslinkers and stable crosslinkers, said particle mixed with a fluid and a cationic crosslinker that is capable of further crosslinking the particle on degradation of the labile crosslinker and exposure of the anionic sites so as to form a gel. A particularly important use is as an injection fluid in petroleum production, where the expandable polymeric particles are injected into target zone and when the heat and/or suitable pH of the target zone cause degradation of the labile crosslinker and the particle expands, the cationic crosslinker crosslinks the polymer to form a gel, thus diverting water to lower permeability regions and improving oil recovery. | 12-16-2010 |
20100314115 | SWELLABLE POLYMER WITH CATIONIC SITES - The invention is directed to long lasting crosslinked water-soluble swellable polymers, methods for making same, and their uses. More particularly, the invention relates to a composition comprising expandable polymeric particles having cationic sites as well as labile crosslinkers and stable crosslinkers, said particle mixed with a fluid. A particularly important use is as an injection fluid in petroleum production, where the expandable polymeric particles are injected into a target zones in the reservoirs and when the heat and/or a suitable pH in the reservoir cause degradation of the labile crosslinker and when the particle expands, the cationic sites in the polymer adsorb to negative sites of the rock in the formation, thus diverting water to lower permeability regions and improving oil recovery. However, many other uses are possible. | 12-16-2010 |
20110129424 | FLUORINATED POLYMERS AND ASSOCIATED METHODS - Compositions comprising a fluorinated polymer and related methods. | 06-02-2011 |
20120037364 | DELAYED GELLING AGENTS - The invention is directed to delayed gelation agents comprising a degradable polymeric cage containing therein one or more gelation agents. The cage degrades in situ, e.g, in an oil reservoir, thus releasing the gelation agent(s), which can then crosslink second polymers in situ to form a gel. | 02-16-2012 |
20120313284 | METHODS OF MANUFACTURING BIOMATERIALS WITH MICROSPHERE GRADIENTS - Methods can prepare tissue engineering scaffolds that include a plurality of biocompatible microspheres linked together to form a three-dimensional matrix. The matrix can include a plurality of pores for growing cells. The biocompatible microspheres can include first and second sets of microspheres. The first set of microspheres can have a first characteristic, and a first predetermined spatial distribution with respect to the three-dimensional matrix. The second set of microspheres can have a second characteristic that is different from the first characteristic, and a second predetermined spatial distribution that is different from the first predetermined spatial distribution with respect to the three-dimensional matrix. The first and second characteristics can selected a composition, polymer, particle size, particle size distribution, type of bioactive agent, type of bioactive agent combination, bioactive agent concentration, amount of bioactive agent, rate of bioactive agent release, mechanical strength, flexibility, rigidity, color, radiotranslucency, radiopaqueness, or the like. | 12-13-2012 |
20130056211 | POLYAMINE-DIHYDROXYBENZOIC ACID CONJUGATE HYDROGELS AS IRON CHELATORS - Compositions and methods for making a composition comprising a polymer and one or more chelators covalently coupled to polymer, wherein the one or more chelators has a benzene ring with more than one hydroxyl group at any position that is free, or a derivative of the chelator, or a salt of the chelator and methods of use. | 03-07-2013 |
20130149383 | SUSTAINED RELEASE PARTICLE FORMULATIONS OF GUAIFENESIN - Sustained release particle formulations formed from a hydrophobic wax matrix and guaifenesin. | 06-13-2013 |
20130195791 | CONJUGATES COMPRISING AN N-OXIME BOND AND ASSOCIATED METHODS - Conjugates comprising a N-oxime bond are disclosed. In one embodiment, a suitable conjugate is represented by the following Formula (I): | 08-01-2013 |
20130216621 | BIFUNCTIONAL CONJUGATE COMPOSITIONS AND ASSOCIATED METHODS - Bifunctional conjugate compositions are provided comprising a Signal-1 moiety bound to a first polymer carrier, wherein the combined size of the Signal-1 moiety and the first polymer carrier is about 1 nanometer to about 500 nanometers; and a Signal-2 moiety bound to a second polymer carrier, wherein the combined size of the Signal-2 moiety and the second polymer carrier is about 1 nanometer to about 500 nanometers. In some embodiments, the Signal-1 moiety and the Signal-2 moiety are bound to the same polymer carrier. Associated methods are also provided. | 08-22-2013 |
20140131043 | SWELLABLE POLYMER WITH ANIONIC SITES - The invention is directed to stable crosslinked water-soluble swellable polymers and methods for making same. More particularly, the invention relates to a composition comprising expandable polymeric particles having anionic sites and labile crosslinkers and stable crosslinkers, said particle mixed with a fluid and a cationic crosslinker that is capable of further crosslinking the particle on degradation of the labile crosslinker and exposure of the anionic sites so as to form a gel. A particularly important use is as an injection fluid in petroleum production, where the expandable polymeric particles are injected into target zone and when the heat and/or suitable pH of the target zone cause degradation of the labile crosslinker and the particle expands, the cationic crosslinker crosslinks the polymer to form a gel, thus diverting water to lower permeability regions and improving oil recovery. | 05-15-2014 |
20140144628 | CROSSLINKING OF SWELLABLE POLYMER WITH PEI - The invention is directed to stable and labile crosslinked water swellable polymeric microparticles that can be further gelled, methods for making same, and their various uses in the hygiene and medical arts, gel electrophoresis, packaging, agriculture, the cable industry, information technology, in the food industry, papermaking, use as flocculation aids, and the like. More particularly, the invention relates to a composition comprising expandable polymeric microparticles having labile crosslinkers and stable crosslinkers, said microparticle mixed with a fluid and an unreacted tertiary crosslinker comprising PEI or other polyamine based tertiary crosslinker that is capable of further crosslinking the microparticle on degradation of the labile crosslinker and swelling of the particle, so as to form a stable gel. A particularly important use is as an injection fluid in petroleum production, where the expandable polymeric microparticles are injected into a well and when the heat and/or pH of the well cause degradation of the labile crosslinker and when the microparticle expands, the tertiary crosslinker crosslinks the polymer to form a stable gel, thus diverting water to lower permeability regions and improving oil recovery. | 05-29-2014 |
20140162912 | SWELLABLE POLYMER WITH CATIONIC SITES - The invention is directed to long lasting crosslinked water-soluble swellable polymers, methods for making same, and their uses. More particularly, the invention relates to a composition comprising expandable polymeric particles having cationic sites as well as labile crosslinkers and stable crosslinkers, said particle mixed with a fluid. A particularly important use is as an injection fluid in petroleum production, where the expandable polymeric particles are injected into a target zones in the reservoirs and when the heat and/or a suitable pH in the reservoir cause degradation of the labile crosslinker and when the particle expands, the cationic sites in the polymer adsorb to negative sites of the rock in the formation, thus diverting water to lower permeability regions and improving oil recovery. However, many other uses are possible. | 06-12-2014 |
20140196894 | FLUORESCENT TAGS FOR DETECTION OF SWELLABLE POLYMERS - The invention is directed to stable crosslinked swellable fluorescently tagged polymeric microparticles, methods for making same, and their various uses. A particularly important use is as an injection fluid in petroleum production, where the expandable polymeric particles are injected into target zone and when the heat and/or suitable pH of the target zone cause degradation of the labile crosslinker and the microparticles expand. The swelled polymer diverts water to lower permeability regions and improves oil recovery. The tags allow monitoring of the presence and concentration of the tagged microparticles and ultimately allow evaluation of the performance of such treatments. Detection of polymeric microparticles in producing wells can be instructive for teaching about the character and extent of thief zones in the subsurface. Better knowledge of the reservoir flow will enable improved application of the gel treatments, improved oil recovery, and allow improved forecasting using simulation modeling. | 07-17-2014 |
20140200678 | BIOMATERIALS WITH MICROSPHERE GRADIENTS AND CORE AND SHELL MICROSPHERES - Methods can prepare tissue engineering scaffolds that include a plurality of biocompatible core/shell microspheres linked together to form a three-dimensional matrix. The matrix can include a plurality of pores for growing cells. The biocompatible microspheres can include first and second sets of microspheres. The first set of microspheres can have a first characteristic, and a first predetermined spatial distribution with respect to the three-dimensional matrix. The second set of microspheres can have a second characteristic that is different from the first characteristic, and a second predetermined spatial distribution that is different from the first predetermined spatial distribution with respect to the three-dimensional matrix. The first and second characteristics can selected a composition, polymer, particle size, particle size distribution, type of bioactive agent, type of bioactive agent combination, bioactive agent concentration, amount of bioactive agent, rate of bioactive agent release, mechanical strength, flexibility, rigidity, color, radiotranslucency, radiopaqueness, or the like. | 07-17-2014 |
20140202693 | NANOGELS FOR DELAYED GELATION - The instant application relates to nanogels or compositions that hold multivalent metal ions until some level of nanogel degradation has occurred, then slowly release the multivalent metal ions for gelation with carboxylate containing polymers. Compositions comprising such nanogels, together with polymers that can be crosslinked with multivalent metal ions, allow the deployment of such mixtures in various applications, and greatly increased gelation times. | 07-24-2014 |
20140209305 | DELAYED GELLING AGENTS - The disclosure is directed to polyelectrolyte complex nanoparticles that can be used to deliver agents deep into hydrocarbon reservoirs. Methods of making and using said polyelectrolyte complex nanoparticles are also provided. | 07-31-2014 |
20140219997 | Templated Islet Cells and Small Islet Cell Clusters for Diabetes Treatment - A population of small reaggregated islets or clusters engineered from individual islet cells and having improved characteristics as compared to native isolated islets. | 08-07-2014 |
20140238702 | LOW PH CROSSLINKING OF POLYMERS - The invention is directed to polymers that self-crosslink at acidic pH or can be crosslinked by phenolic agents in brine. Such polymers have lower viscosity and can be pumped deep into reservoirs, where they will cross link in situ, thus increasing their viscosity and/or form a gel and blocking thief zones. Methods of making and using such polymers are also provided. | 08-28-2014 |
20140294980 | SUSTAINED RELEASE PARTICLE FORMULATIONS - Particles for delivery of active ingredients formed from an active ingredient and a hydrophobic matrix, as well as methods for making such particles. | 10-02-2014 |
20150080333 | HYALURONIC ACID PARTICLES AND THEIR USE IN BIOMEDICAL APPLICATIONS - Hyaluronic acid particles and their use in biomedical applications are provided. In one embodiment, an HA particle comprising a plurality of free polymer chains extending from a surface of the particle such that the polymer chains are capable of association with polymers or with polymer chains on a surface of other particles is provided. | 03-19-2015 |