Cools
Brecht Cools, Willebroek BE
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20140138299 | MEMBRANE DISTILLATION APPARATUS - Described herein is air gap membrane distillation apparatus comprising a module ( | 05-22-2014 |
Jan Cools, Herent BE
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20100130586 | DIAGNOSIS AND TREATMENT OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA - The present invention relates to the field of biotechnological means to diagnose or treat T-cell acute lymphoblastic leukaemia. More particularly, the invention relates to methods to diagnose T-cell acute lymphoblastic leukaemia via determining the presence of a duplication of the MYB gene in cells taken from patients. The invention further relates to inhibitors capable of neutralizing the biological activity of MYB alone, or in combination with inhibitors capable of neutralizing the biological activity of NOTCH1, which can be used to treat T-cell acute lymphoblastic leukaemia. | 05-27-2010 |
Jan Cools, Leuven BE
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20090075972 | Use of Midostaurin for Treating Gastrointestinal Stromal Tumors - The present invention relates to the use of midostaurin, in free form or in pharmaceutically acceptable salt form in the manufacture of a pharmaceutical composition for the treatment of gastrointestinal stromal tumors, and to a method of treatment of warm-blooded animals, preferably humans, in which a therapeutically effective dose of midostaurin is administered to an animal suffering from said disease or condition. | 03-19-2009 |
20090076024 | Episomal Fusion Gene - The present invention relates to an episomal structure expressing a functional oncogene, whereby said oncogene is a fusion gene of two chromosomal gene fragments. More specifically, the invention relates to a NUP214-ABL1 fusion product, important in the development of T-cell acute lymphoblastic leukemia, to methods to detect the fusion and to methods to prevent the oncogenic activity of said fusion product. | 03-19-2009 |
20110033911 | Episomal fusion gene - The present invention relates to an episomal structure expressing a functional oncogene, whereby said oncogene is a fusion gene of two chromosomal gene fragments. More specifically, the invention relates to a NUP214-ABL1 fusion product, important in the development of T-cell acute lymphoblastic leukemia, to methods to detect the fusion and to methods to prevent the oncogenic activity of said fusion product. | 02-10-2011 |
Jan Jozef Cools, Balen BE
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20080308535 | Atmospheric-Pressure Plasma Jet - A plasma jet apparatus for performing plasma processing of an article includes: an elongated central electrode ( | 12-18-2008 |
Marina Cools, Relie BE
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20090298897 | Treatment of Inflammatory Disorders With Triazole Compounds - The present invention relates to the use of triazole compounds for reducing inflammation and treating inflammation-associated disorders. | 12-03-2009 |
Marina Cools, Turnhout BE
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20120184537 | [1,4]-BENZODIAZEPINES AS VASOPRESSIN V2 RECEPTOR ANTAGONISTS - The invention relates to a novel class of [1,4]-benzodiazepine derivatives, processes for their preparation, intermediates usable in these processes, and pharmaceutical compositions containing the compounds. Other aspects of the invention are directed to the use of said [1,4]-benzodiazepine derivatives in therapy based on the capability of said compounds to interfere with the binding of the peptide hormone, vasopressin, to its receptors. In particular as vasopressin V2 receptor antagonists and therefore useful for treating involving increased vascular resistance, cardiac insufficiency, and water retention. | 07-19-2012 |
Marina Lucie Louise Cools, Retie BE
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20090192206 | MERCAPTOIMIDAZOLES AS CCR2 RECEPTOR ANTAGONISTS - The present invention relates to a compound of formula (I) | 07-30-2009 |