Christiano
Angela Christiano, Mahwah, NJ US
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20150071934 | Methods For Regulating Hair Growth Disorders - The invention provides for methods for treating a hair loss disorder in a subject by administering a FGF13 inhibitor. The invention further provides for methods for treating a hair growth disorder in a subject by administering a FGF13 activator. | 03-12-2015 |
Angela Christiano, Upper Saddle River, NJ US
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20130324586 | Inhibition of Hairless Protein mRNA - Methods for inhibition of hairless protein mRNA using RNA interference is described, in particular methods for hair removal. Also described are nucleic acid constructs for RNAi-mediated inhibition of hairless protein mRNA and compositions including such constructs. | 12-05-2013 |
Angela M. Christiano, Saddle River, NJ US
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20080287359 | CADHERIN-11-MEDIATED MODULATION OF HAIR GROWTH - The present invention provides for methods of inhibiting hair growth, comprising decreasing the level of CAD1 1 mRNA and/or protein in hair follicle cells of a subject. The present invention further provides for methods of promoting hair growth, comprising increasing the level of CADI 1 mKNA and/or protein in hair follicle cells of a subject. The invention also provides for transgenic animals with aberrancies in CADI 1 expression, and for assay systems (including transgenic animals and cell-based systems) that may be used to identify agents that decrease or increase CADI 1 expression. | 11-20-2008 |
20100137416 | CADHERIN-11-MEDIATED MODULATION OF HAIR GROWTH - The present invention provides for methods of inhibiting hair growth, comprising decreasing the level of CAD1 1 mRNA and/or protein in hair follicle cells of a subject. The present invention further provides for methods of promoting hair growth, comprising increasing the level of CADI 1 mKNA and/or protein in hair follicle cells of a subject. The invention also provides for transgenic animals with aberrancies in CADI 1 expression, and for assay systems (including transgenic animals and cell-based systems) that may be used to identify agents that decrease or increase CADI 1 expression. | 06-03-2010 |
20110189199 | METHODS FOR P2RY5 MEDIATED REGULATION OF HAIR GROWTH AND MUTANTS THEREOF - The invention provides for a method for screening compounds that bind to and modulate the hair-specific G-protein coupled receptor, P2RY5. The invention further provides for methods for controlling hair growth by administering a P2RY5 modulating compound to a subject. | 08-04-2011 |
20120003244 | METHODS FOR APCDD1 MEDIATED REGULATION OF HAIR GROWTH AND PIGMENTATION AND MUTANTS THEREOF - The invention provides for methods for controlling hair growth by administering an APCDD1 modulating compound to a subject. The invention further provides for a method for screening compounds that bind to and modulate APCDD1. | 01-05-2012 |
20140134188 | Methods for P2RY5 Mediated Regulation of Hair Growth and Mutants Thereof - The invention provides for a method for screening compounds that bind to and modulate the hair-specific G-protein coupled receptor, P2RY5. The invention farther provides for methods for controlling hair growth by administering a P2RY5 modulating compound to a subject. | 05-15-2014 |
Angela M. Christiano, Upper Saddle River, NJ US
Patent application number | Description | Published |
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20090208484 | R-SPONDIN COMPOSITIONS AND METHODS OF USE THEREOF - The invention provides for a method for screening compounds that bind to and modulate a regulator of Wnt signaling, R-spondin 4. The invention further provides for methods for diagnosing a keratin-related abnormality, such as anonychia congenital, in a subject. The invention also provides for isolated RSPO4 mutant molecules. | 08-20-2009 |
20100303767 | METHODS FOR COMPACT AGGREGATION OF DERMAL CELLS - The invention provides for a method for aggregating dermal papilla cells or dermal sheath cells or a combination thereof, the method comprising: growing dermal papilla cells or dermal sheath cells or a combination thereof in suspension culture; and contacting the culture with an effective amount of an enzyme, wherein a substrate of the enzyme is an extracellular matrix molecule in the suspension culture, so as to aggregate dermal papilla cells or dermal sheath cells. The culture may be a hanging drop culture and the enzyme may be a hyaluronidase. | 12-02-2010 |
Angela M. Christiano, Mahwah, NJ US
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20130078244 | METHODS FOR DETECTING AND REGULATING ALOPECIA AREATA AND GENE COHORTS THEREOF - The invention provides for methods for controlling hair growth by administering a HLDGC modulating compound to a subject. The invention further provides for a method for screening compounds that bind to and modulate polypeptides encoded by HLDGC genes. The invention also provides methods of detecting the presence of or a predisposition to a hair-loss disorder in a human subject as well as methods of treating such disorders. | 03-28-2013 |
20140065153 | Methods for Treating Hair Loss Disorders - The invention provides for methods for treating a hair loss disorder in a subject by administering a JAK/STAT inhibitor. | 03-06-2014 |
Angela M. Christiano, West Orange, NJ US
Patent application number | Description | Published |
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20090004169 | Nucleic Acids For Inhibiting Hairless Protein Expression and Methods of Use Thereof - The present invention provides DNAzymes and ribozymes that specifically cleave Hairless protein mRNA. The present invention also provides antisense oligonucleotides that specifically inhibit translation of Hairless Protein mRNA. The present invention also provides various methods of inhibiting the expression of Hairless Protein. Finally the invention provides pharmaceutical compositions containing the instant DNAzymes, ribozymes and antisense oligonucleotides as active ingredients. | 01-01-2009 |
20100221318 | NUCLEIC ACIDS FOR INHIBITING HAIRLESS PROTEIN EXPRESSION AND METHODS OF USE THEREOF - The present invention provides DNAzymes and ribozymes that specifically cleave Hairless protein mRNA. The present invention also provides antisense oligonucleotides that specifically inhibit translation of Hairless Protein mRNA. The present invention also provides various methods of inhibiting the expression of Hairless Protein. Finally the invention provides pharmaceutical compositions containing the instant DNAzymes, ribozymes and antisense oligonucleotides as active ingredients. | 09-02-2010 |
Fabio Fortunato Christiano, Itapira-Sp BR
Patent application number | Description | Published |
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20130316599 | CONNECTOR FOR TERMINATING TO A TERMINAL POST - A connector for terminating to a terminal post. The connector has a connector body and a lever. The connector body has clamping arms, with the clamping arms having outwardly directed cam surfaces. The lever is connected to the connector body for pivotal movement thereabout between an unclamped position and a clamped position. The lever has activation members with inwardly directed cam surfaces. The rotation of the lever from the unclamped position to the clamped position causes the inwardly directed cam surface to progressively engage the outwardly directed cam surfaces, causing the clamping arms to be moved toward each other thereby clamping the connector to the terminal post without the need for tools. | 11-28-2013 |
20140363997 | CONNECTOR WITH RESILIENT LATCHES TO ACCOMMODATE MOUNTING TO CURVED OR ARCUATE SURFACES - An electrical connector and method for mounting to mating member with an arcuate cylindrical member. The electrical connector includes a housing and a mounting member extending from the housing. The mounting member has latching members and a mating member receiving section. The mating member receiving section has an arcuate configuration which cooperates with the arcuate cylindrical member to maintain the electrical connector on the arcuate cylindrical member. The latching members have latching arms, with each latching arm having an arcuate configuration which cooperates with the a surface of the mating member to prevent unwanted rotation of the electrical connector relative to the mating member. | 12-11-2014 |
20150056862 | BULB SOCKET - A bulb socket for receiving a bulb therein. The bulb socket includes a first portion and a second portion. The first portion has a bulb receiving opening. The second portion extends from the first portion. The second portion has first outside surfaces which are tapered inward, such that the perimeter of the second portion proximate the first portion is less than the perimeter of the second portion spaced from the first portion. The second portion does not obstruct the performance of the bulb, allowing approximately all of the light capacity of the bulb to be utilized. | 02-26-2015 |
John P. Christiano, Old Lyme, CT US
Patent application number | Description | Published |
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20120090819 | HEATER-COOLER SYSTEM FOR A BARREL OF AN EXTRUDER AND A METHOD OF USING THE SAME - A heater-cooler system for a barrel of an extruder is disclosed. The system includes a heater adapted to be in thermal communication with at least a portion of a barrel of an extruder. The system further includes a shroud assembly that defines a cavity. The shroud assembly encloses the heater. The shroud assembly has an intake port and an exhaust port. A valve is in fluid communication with the exhaust port. The valve is moveable between an open position and a closed position. When the valve is in the closed position the exhaust port is substantially sealed. When the valve is moved between the closed position and the open position or is in the open position the cavity is in fluid communication an area outside of the cavity through the exhaust port. | 04-19-2012 |
20140265059 | APPARATUS FOR MANUFACTURING AND PROCESSING FILMS HAVING STRIPS OF INCREASED THICKNESS - A device for producing film includes a die defining a die outlet through which molten polymer is extruded. The polymer is suitable for producing one of a pre-stretch film and a conventional stretch film. The device includes a film producing device spaced apart from the die. One or more coolant supplies are positioned proximate the film producing device for directing a stream of coolant onto the molten polymer positioned on the film producing device and/or between the die and film producing device, for producing film having strips of increased thickness. | 09-18-2014 |
20140272305 | APPARATUS FOR MANUFACTURING AND PROCESSING PRE-STRETCH FILMS HAVING STRIPS OF INCREASED THICKNESS - A device for producing pre-stretch film includes a die defining a die outlet through which molten polymer is extruded. The polymer is suitable for producing the pre-stretch film. A film producing device is spaced apart from the die. One or more coolant supplies are positioned proximate the film producing device for directing a stream of coolant onto the molten polymer positioned on the film producing device. | 09-18-2014 |
20140272306 | APPARATUS FOR MANUFACTURING AND PROCESSING PRE-STRETCH FILMS HAVING STRIPS OF INCREASED THICKNESS - A method for maximizing a width of a pre-stretch film includes providing polymer being suitable for producing the pre-stretch film. A pre-stretch film having strips of increased thickness is produced. The method includes coordinating a thickness of the strips of increased thickness with a formation of edge thickening caused by neck-in during stretching of the pre-stretch film. | 09-18-2014 |
Steven P. Christiano, Spartanburg, SC US
Patent application number | Description | Published |
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20140296379 | AMINE-TERMINATED, SUBSTANTIALLY LINEAR SILOXANE COMPOUND AND EPOXY PRODUCTS MADE WITH THE SAME - An amine-terminated, substantially linear siloxane compound comprises siloxane repeating units conforming to specified structures, one of which contains pendant aromatic groups. The amine-terminated, substantially linear siloxane compound further comprises amine-substituted terminal siloxy groups. An epoxy product is made by reacting an epoxy resin and the amine-terminated, substantially linear siloxane compound. | 10-02-2014 |