Chernikova
Anna Grigorievna Chernikova, Moscow RU
Patent application number | Description | Published |
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20160000379 | METHOD AND APPARATUS FOR DYNAMIC ASSESSMENT AND PROGNOSIS OF THE RISKS OF DEVELOPING PATHOLOGICAL STATES - A method and apparatus for health risk assessment by means of measuring and evaluating the functional state of the mechanisms of physiological adaptation of human organism comprises recording analog signals of heartbeat intervals, filtering the analog signals of heartbeat intervals, converting the analog signals to digital signals of heartbeat intervals, transmitting the digital signals of heartbeat intervals to a central processing unit, detecting R-peaks from the digital signals of heartbeat intervals, measuring time intervals between two consecutive said R-peaks, calculating heartbeat variability parameters from said heartbeat intervals, calculating degree of tension (DT) of regulatory mechanisms and their functional reserve (FR) based on said heartbeat variability parameters, calculating plurality of functional states based on the DT and FR, and calculating posteriori probabilities based on plurality of functional states, wherein probabilities of health risk is determined based on values of DT, FR, at least one functional state and the posteriori probabilities. | 01-07-2016 |
Tatjana Chernikova, Tashkent UZ
Patent application number | Description | Published |
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20090255014 | Transgenic organisms with lower growth temperature - The invention relates to the growth temperature of organisms, especially plants and microorganisms and the manipulation of the tolerable cultivation temperature. More specifically, the present invention relates to the expression of heterologous proteins in microorganisms, and especially to the heterologous expression of heat sensitive proteins in bacteria, either gram-negative or gram-positive. In a first aspect, the present invention provides a method for manipulation of cells and the resultant cells, wherein at least one gene from a psychrophilic micro organism coding for at least one chaperone or chaperonin is expressed. Such cells are selected among cultivated eukaryotic cells, i.e. animal and plant cells and entire plants, gram-negative and gram-positive bacteria, fungi and yeasts. | 10-08-2009 |
Tatyana Chernikova, Tashkent UZ
Patent application number | Description | Published |
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20090305339 | Polypeptides With Laccase Activity - The invention relates to a new laccase from rumen, namely the RL5 laccase. In particular, the invention relates to a polypeptide comprising the amino acid sequence shown in | 12-10-2009 |
Tatyana Chernikova, Braunschweig DE
Patent application number | Description | Published |
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20080261267 | Cellulases from Rumen - The invention provides polypeptides coding for new cellulases from rumen, particularly from rumen ecosystem. The invention also relates to functional fragments or functional derivatives thereof as well as to nucleic acids encoding the polypeptides of the invention, vectors and host cells containing said nucleic acids, a method for producing the polypeptides and the use of the polypeptides according to the present invention for various industrial purposes and medical treatments. | 10-23-2008 |
20090078384 | Esterases from rumen - The invention provides polypeptides coding for new esterases from rumen. The invention also relates to functional fragments or functional derivatives thereof as well as to nucleic acids encoding the polypeptides of the invention, vectors and host cells containing said nucleic acids, a method for producing the polypeptides and the use of the polypeptides according to the present invention for various industrial purposes and medical treatments. The invention also relate to the conversion of said esterases into lipases. | 03-26-2009 |
20120231972 | Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same - The present invention relates to a probe compound that can comprise any substrate or metabolite of an enzymatic reaction in addition to an indicator component, such as, for example, a fluorescence dye, or the like. Moreover, the present invention relates to means for detecting enzymes in form of an array, which comprises any number of probe compounds of the invention which each comprise a different metabolite of interconnected metabolites representing the central pathways in all forms of life. Moreover, the present invention relates to a method for detecting enzymes involving the application of cell extracts or the like to the array of the invention which leads to reproducible enzymatic reactions with the substrates. These specific enzymatic reactions trigger the indicator (e.g. a fluorescence signal) and bind the enzymes to the respective cognate substrates. Moreover, the invention relates to means for isolating enzymes in form of nanoparticles coated with the probe compound of the invention. The immobilisation of the cognate substrates or metabolites on the surface of nanoparticles by means of the probe compounds allows capturing and isolating the respective enzyme, e.g. for subsequent sequencing. | 09-13-2012 |