Patent application number | Description | Published |
20140152957 | OPTIC NEUROPATHY DETECTION WITH THREE-DIMENSIONAL OPTICAL COHERENCE TOMOGRAPHY - Based on optical coherence tomography (OCT) imaging of a portion of an eye, a mask of an anatomical feature is derived. Using the mask as a reference, a scan path is determined that is at least partially fitted to and/or partially enclosing the mask. OCT scan data corresponding to the scan path is acquired and analyzed to detect optic neuropathies. | 06-05-2014 |
20140160263 | DATA VISUALIZATION METHOD AND APPARATUS UTILIZING RECEIVER OPERATING CHARACTERISTIC ANALYSIS - A system and method for presenting experimentally-determined data relating to a region of interest on a medical patient to a user. A computer memory stores a ROC analysis of historical data for a region of interest of a plurality of different subjects. A computer processor is programmed to compare the experimentally-determined data to historical data based on the ROC analysis of the historical data and identify the experimentally-determined data to be utilized in reaching an at least preliminary conclusion regarding the medical patient. A display device is operatively connected to the computer processor to present a visible display graphically depicting a result of the comparison performed by the processor. | 06-12-2014 |
20140218686 | ATTENUATION-BASED OPTIC NEUROPATHY DETECTION WITH THREE-DIMENSIONAL OPTICAL COHERENCE TOMOGRAPHY - Optical coherence tomography (OCT) scan data of a subject is acquired over a region of interest which can include an optic disc or a macula of a retina. Layer boundaries of retinal layers are identified in the OCT scan data to facilitate measurements. In one aspect, a measurement related to ratio value between a total backscattered signal intensity of one or more target layers of the retina and a total backscattered signal intensity of one or more reference layers is computed on a location-by-location basis within a region of interest of the OCT scan data. Measurements can be collected, aggregated, analyzed, and displayed in connection with other information taken or derived from the OCT scan data. | 08-07-2014 |
20140270444 | OPTIC DISC IMAGE SEGMENTATION METHOD AND APPARATUS - Provided is a method of processing image data and detecting a region of an image represented by the image data to be excluded from an analysis of the image. According to the method, image data captured by a medical modality is received. An evaluation of a portion of the image data representing a two-dimensional view of a subject appearing in the image is conducted to locate, in the two-dimensional view, the region to be excluded from the analysis of the image. A feature pertinent to the analysis appearing in a remaining portion of the image, that is outside of the region to be excluded from the analysis located by the evaluation, is detected. | 09-18-2014 |
20140293289 | Method for Generating Two-Dimensional Images From Three-Dimensional Optical Coherence Tomography Interferogram Data - Methods for generating optical coherence tomography intensity maps are provided. A beam of light is generated and divided along a sample path and a reference path. The sample path beam of light is directed to locations in an X-Y plane. Light returned from each of the sample path and the reference path is received. Sets of outputs are generated, each corresponding to light intensities received at different wavelengths of the light source when the beam of light is directed at a particular X-Y plane location, the light intensities including information about a light reflectance distribution within an object in a depth direction Z at the particular X-Y plane location. A set of outputs generated from directing the beam of light at a particular X-Y plane location is high-pass filtered to generate a set of filtered outputs suitable for generating a two-dimensional image intensity map of the object. | 10-02-2014 |
20150015845 | OPTICAL COHERENCE TOMOGRAPHY WITH DYNAMIC FOCUS SWEEPING AND WINDOWED AVERAGING - During scan capture with an OCT imaging system, the focal plane position can be simultaneously shifted over at least a portion of an image range. As a result, a plurality of image frames respectively corresponding to various focal plane positions is acquired. The image frames can be combined to generate a composite image having suitable resolution throughout the image range, including regions associated with weak-intensity or low-reflectance features. Further, windowed averaging can be performed prior to generation of the composite image so that the composite image incorporates weights given to image data in focus. | 01-15-2015 |
20150201829 | GEOGRAPHIC ATROPHY IDENTIFICATION AND MEASUREMENT - Geographic atrophy of the eye can be detected and measured by imaging the eye at a depth greater than the retinal pigment epithelium (RPE) at a plurality of locations of the eye, for example, using optical coherence tomography (OCT); determining a ratio of the intensities of imaging signals of a retinal layer(s) with respect to the intensity of imaging signals of a sub-RPE layer(s) at each location; determining representative values based at least in part on the determined ratios; generating a map of the representative values; and identifying diseased areas from the map. Contours and binary maps may be generated based on the identified diseased areas. The size and shape of the identified areas may be analyzed and monitored over a period of time. | 07-23-2015 |
20150204651 | DETECTION OF MISSAMPLED INTERFEROGRAMS IN FREQUENCY DOMAIN OCT WITH A K-CLOCK - Optical coherence tomography light sources can be non-linear and attempts to linearize them can lead to asynchrony between the light source and A-line scans and missampling in the scans causing signal noise. Accordingly, a system and methods are provided herein to detect missampling by obtaining a plurality of interferograms; providing at least two wavenumber reference signals at different wavenumbers, wherein the wavenumber reference signals comprise attenuated or enhanced portions of each of the plurality of interferograms; aligning each of the plurality of interferograms according to one of the at least two wavenumber reference signals; and for each of the plurality of interferograms, identifying an interferogram as missampled if another of the at least two reference signals does not align with a corresponding reference signal in a statistically significant number of the plurality of interferograms. An optical element, for example, an optical notch, may be used to generate the reference signals. | 07-23-2015 |